Identification and biological activity of 6-alkyl-substituted 3-methyl-pyridine-2-carbonyl amino dimethyl-benzoic acid EP4 antagonists von Blanco, Maria-Jesus, Vetman, Tatiana, Chandrasekhar, Srinivasan, Fisher, Matthew J., Harvey, Anita, Kuklish, Steven L., Chambers, Mark, Lin, Chaohua, Mudra, Daniel, Oskins, Jennifer, Wang, Xu-Shan, Yu, Xiao-Peng, Warshawsky, Alan M.

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Discovery of LY3104607: A Potent and Selective G Protein-Coupled Receptor 40 (GPR40) Agonist with Optimized Pharmacokinetic Properties to Support Once Daily Oral Treatment in Patie... von Hamdouchi, Chafiq, Maiti, Pranab, Warshawsky, Alan M, DeBaillie, Amy C, Otto, Keith A, Wilbur, Kelly L, Kahl, Steven D, Patel Lewis, Anjana, Cardona, Guemalli R, Zink, Richard W, Chen, Keyue, CR, Siddaramaiah, Lineswala, Jayana P, Neathery, Grace L, Bouaichi, Cecilia, Diseroad, Benjamin A, Campbell, Alison N, Sweetana, Stephanie A, Adams, Lisa A, Cabrera, Over, Ma, Xiaosu, Yumibe, Nathan P, Montrose-Rafizadeh, Chahrzad, Chen, Yanyun, Miller, Anne Reifel

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Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1 von Partridge, Katherine M., Antonysamy, Stephen, Bhattachar, Shobha N., Chandrasekhar, Srinivasan, Fisher, Matthew J., Fretland, Adrian, Gooding, Karen, Harvey, Anita, Hughes, Norman E., Kuklish, Steven L., Luz, John G., Manninen, Peter R., McGee, James E., Mudra, Daniel R., Navarro, Antonio, Norman, Bryan H., Quimby, Steven J., Schiffler, Matthew A., Sloan, Ashley V., Warshawsky, Alan M., Weller, Jennifer M., York, Jeremy S., Yu, Xiao-Peng

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Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors von Kuklish, Steven L., Antonysamy, Stephen, Bhattachar, Shobha N., Chandrasekhar, Srinivasan, Fisher, Matthew J., Fretland, Adrian J., Gooding, Karen, Harvey, Anita, Hughes, Norman E., Luz, John G., Manninen, Peter R., McGee, James E., Navarro, Antonio, Norman, Bryan H., Partridge, Katherine M., Quimby, Steven J., Schiffler, Matthew A., Sloan, Ashley V., Warshawsky, Alan M., York, Jeremy S., Yu, Xiao-Peng

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Discovery of potent aryl-substituted 3-[(3-methylpyridine-2-carbonyl) amino]-2,4-dimethyl-benzoic acid EP4 antagonists with improved pharmacokinetic profile von Blanco, Maria-Jesus, Vetman, Tatiana, Chandrasekhar, Srinivasan, Fisher, Matthew J., Harvey, Anita, Chambers, Mark, Lin, Chaohua, Mudra, Daniel, Oskins, Jennifer, Wang, Xu-Shan, Yu, Xiao-Peng, Warshawsky, Alan M.

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Discovery of substituted-2,4-dimethyl-(naphthalene-4-carbonyl)amino-benzoic acid as potent and selective EP4 antagonists von Blanco, Maria-Jesus, Vetman, Tatiana, Chandrasekhar, Srinivasan, Fisher, Matthew J., Harvey, Anita, Mudra, Daniel, Wang, Xu-Shan, Yu, Xiao-Peng, Schiffler, Matthew A., Warshawsky, Alan M.

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2-Alkoxydihydrocinnamates as PPAR agonists. Activity modulation by the incorporation of phenoxy substituents von Martín, José A., Brooks, Dawn A., Prieto, Lourdes, González, Rosario, Torrado, Alicia, Rojo, Isabel, López de Uralde, Beatriz, Lamas, Carlos, Ferritto, Rafael, Dolores Martín-Ortega, María, Agejas, Javier, Parra, Francisco, Rizzo, John R., Rhodes, Gary A., Robey, Roger L., Alt, Charles A., Wendel, Samuel R., Zhang, Tony Y., Reifel-Miller, Anne, Montrose-Rafizadeh, Chahrzad, Brozinick, Joseph T., Hawkins, Eric, Misener, Elizabeth A., Briere, Daniel A., Ardecky, Robert, Fraser, James D., Warshawsky, Alan M.

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Discovery and characterization of a potent and selective EP4 receptor antagonist von Schiffler, Matthew A., Chandrasekhar, Srinivasan, Fisher, Matthew J., Harvey, Anita, Kuklish, Steven L., Wang, Xu-Shan, Warshawsky, Alan M., York, Jeremy S., Yu, Xiao-Peng

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Asymmetric total synthesis of dibenzocyclooctadiene lignans (-)-schizandrin and (-)-isoschizandrin. Structure revision of (+)-isoschizandrin von Warshawsky, Alan M, Meyers, A. I

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Analgesic and anti‐inflammatory properties of novel, selective, and potent EP4 receptor antagonists von Chandrasekhar, Srinivasan, Yu, Xiao‐Peng, Harvey, Anita K., Oskins, Jennifer L., Lin, Chaohua, Wang, Xushan, Blanco, Maria‐Jesus, Fisher, Matthew J., Kuklish, Steven L., Schiffler, Matthew A., Vetman, Tatiana, Warshawsky, Alan M., York, Jeremy S., Bendele, Alison M., Chambers, Mark G.

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Design and Synthesis of 2-Methyl-2-{4-[2-(5-methyl-2-aryloxazol- 4-yl)ethoxy]phenoxy}propionic Acids:  A New Class of Dual PPARα/γ Agonists von Brooks, Dawn A, Etgen, Garret J, Rito, Christopher J, Shuker, Anthony J, Dominianni, Samuel J, Warshawsky, Alan M, Ardecky, Robert, Paterniti, James R, Tyhonas, John, Karanewsky, Donald S, Kauffman, Raymond F, Broderick, Carol L, Oldham, Brian A, Montrose-Rafizadeh, Chahzrad, Winneroski, Leonard L, Faul, Margaret M, McCarthy, James R

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Design and synthesis of novel and potent amide linked PPARγ/δ dual agonists von Shi, Qing, Canada, Emily J., Xu, Yanping, Warshawsky, Alan M., Etgen, Garret J., Broderick, Carol L., Clutinger, Cathleen K., Irwin, Lynnie A., Laurila, Michael E., Montrose-Rafizadeh, Chahrzad, Oldham, Brian A., Wang, Minmin, Winneroski, Leonard L., Xie, Chaoyu, York, Jeremy S., Yumibe, Nathan P., Zink, Richard W., Mantlo, Nathan

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Tetrahydroisoquinoline PPARγ agonists: Design of novel, highly selective non-TZD antihyperglycemic agents von Henry, James R., Li, Yihong, Warshawsky, Alan M., Brozinick, Joseph T., Hawkins, Eric D., Misener, Elizabeth A., Briere, Daniel A., Montrose-Rafizadeh, Chahrzad, Zink, Richard W., Yumibe, Nathan P., Ajamie, Rose T., Wilken, Brad, Devanarayan, Viswanath

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Synthesis and evaluation of aminomethyl dihydrocinnamates as a new class of PPAR ligands von Warshawsky, Alan M., Alt, Charles A., Brozinick, Joseph T., Harkness, Allen R., Hawkins, Eric D., Henry, James R., Matthews, Donald P., Miller, Anne R., Misener, Elizabeth A., Montrose-Rafizadeh, Chahrzad, Rhodes, Gary A., Shen, Quanrong, Vance, Jennifer A., Udodong, Uko E., Wang, Minmin, Zhang, Tony Y., Zink, Richard W.

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Inhibition of thrombin activatable fibrinolysis inhibitor by cysteine derivatives von Do, Yee H., Gifford-Moore, Donetta S., Beight, Douglas W., Rathnachalam, Radhakrishnan, Klimkowski, Valentine J., Warshawsky, Alan M., Lu, Deshun

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An approach toward the ophiobolane sesterterpenes: synthesis of the ceroplastin nucleus von Dauben, William G, Warshawsky, Alan M

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Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1 von Partridge, Katherine M., Antonysamy, Stephen, Bhattachar, Shobha N., Chandrasekhar, Srinivasan, Fisher, Matthew J., Fretland, Adrian, Gooding, Karen, Harvey, Anita, Hughes, Norman E., Kuklish, Steven L., Luz, John G., Manninen, Peter R., McGee, James E., Mudra, Daniel R., Navarro, Antonio, Norman, Bryan H., Quimby, Steven J., Schiffler, Matthew A., Sloan, Ashley V., Warshawsky, Alan M., Weller, Jennifer M., York, Jeremy S., Yu, Xiao-Peng

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Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors von Kuklish, Steven L., Antonysamy, Stephen, Bhattachar, Shobha N., Chandrasekhar, Srinivasan, Fisher, Matthew J., Fretland, Adrian J., Gooding, Karen, Harvey, Anita, Hughes, Norman E., Luz, John G., Manninen, Peter R., McGee, James E., Navarro, Antonio, Norman, Bryan H., Partridge, Katherine M., Quimby, Steven J., Schiffler, Matthew A., Sloan, Ashley V., Warshawsky, Alan M., York, Jeremy S., Yu, Xiao-Peng

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Synthesis of N,N‘-Orthogonally Protected (S)-Piperazine-2-carboxylic Acid von Warshawsky, Alan M, Patel, Meena V, Chen, Teng-Man

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Tetrahydroisoquinoline PPARgamma agonists: design of novel, highly selective non-TZD antihyperglycemic agents von Henry, James R, Li, Yihong, Warshawsky, Alan M, Brozinick, Joseph T, Hawkins, Eric D, Misener, Elizabeth A, Briere, Daniel A, Montrose-Rafizadeh, Chahrzad, Zink, Richard W, Yumibe, Nathan P, Ajamie, Rose T, Wilken, Brad, Devanarayan, Viswanath

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