PIK3CA mutation, but not PTEN loss of function, determines the sensitivity of breast cancer cells to mTOR inhibitory drugs von Weigelt, B, Warne, P H, Downward, J

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Rictor is a novel target of p70 S6 kinase-1 von Treins, C, Warne, P H, Magnuson, M A, Pende, M, Downward, J

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Phosphatidylinositol-3-OH kinase direct target of Ras von Rodriguez-Viciana, Pablo, Warne, Patricia H, Dhand, Ritu, Vanhaesebroeck, Bart, Gout, Ivan, Fry, Michael J, Waterfield, Michael D, Downward, Julian

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Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro von Warne, Patricia H, Vician, Pablo Rodrigueza, Downward, Julian

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Activation of phosphoinositide 3‐kinase by interaction with Ras and by point mutation von Rodriguez‐Viciana, P., Warne, P. H., Vanhaesebroeck, B., Waterfield, M. D., Downward, J.

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Murine Ksr interacts with MEK and inhibits Ras-induced transformation von Denouel-Galy, A., Douville, E.M., Warne, P.H., Papin, C., Laugier, D., Calothy, G., Downward, J., Eychène, A.

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Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway von Khwaja, Asim, Rodriguez-Viciana, Pablo, Wennström, Stefan, Warne, Patricia H., Downward, Julian

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Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras von Rodriguez-Viciana, Pablo, Warne, Patricia H, Khwaja, Asim, Marte, Barbara M, Pappin, Darryl, Das, Pamela, Waterfield, Michael D, Ridley, Anne, Downward, Julian

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R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways von Marte, Barbara M., Rodriguez-Viciana, Pablo, Wennström, Stefan, Warne, Patricia H., Downward, Julian

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Stimulation of p21ras upon T-cell activation von Downward, Julian, Graves, Jonathan D., Warne, Patricia H., Rayter, Sydonia, Cantrell, Doreen A.

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Regulators of Mitotic Arrest and Ceramide Metabolism Are Determinants of Sensitivity to Paclitaxel and Other Chemotherapeutic Drugs von Swanton, Charles, Marani, Michela, Pardo, Olivier, Warne, Patricia H., Kelly, Gavin, Sahai, Erik, Elustondo, Frédéric, Chang, Jenny, Temple, Jillian, Ahmed, Ahmed A., Brenton, James D., Downward, Julian, Nicke, Barbara

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Binding of Ras to Phosphoinositide 3-Kinase p110α Is Required for Ras- Driven Tumorigenesis in Mice von Gupta, Surbhi, Ramjaun, Antoine R., Haiko, Paula, Wang, Yihua, Warne, Patricia H., Nicke, Barbara, Nye, Emma, Stamp, Gordon, Alitalo, Kari, Downward, Julian

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Phosphatidylinositol 3$^{\prime}$ Kinase: One of the Effectors of Ras [and Discussion] von Rodriguez-Viciana, Pablo, Marte, Barbara M., Warne, Patricia H., Downward, Julian, Karin, M., Marshall, C. J.

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CUTL1 is a target of TGFβ signaling that enhances cancer cell motility and invasiveness von Michl, Patrick, Ramjaun, Antoine R., Pardo, Olivier E., Warne, Patricia H., Wagner, Martin, Poulsom, Richard, D’Arrigo, Corrado, Ryder, Kenneth, Menke, Andre, Gress, Thomas, Downward, Julian

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Placental-type alkaline phosphatase in cervical neoplasia von MCLAUGHLIN, P. J, WARNE, P. H, HUTCHINSON, G. E, JOHNSON, P. M, TUCKER, D. F

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The growth factor IL-2 activates p21ras proteins in normal human T lymphocytes von Graves, JD, Downward, J, Izquierdo-Pastor, M, Rayter, S, Warne, PH, Cantrell, DA

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Involvement of MINK, a Ste20 Family Kinase, in Ras Oncogene-Induced Growth Arrest in Human Ovarian Surface Epithelial Cells von Nicke, Barbara, Bastien, Julie, Khanna, Sophia J., Warne, Patricia H., Cowling, Victoria, Cook, Simon J., Peters, Gordon, Delpuech, Oona, Schulze, Almut, Berns, Katrien, Mullenders, Jasper, Beijersbergen, Roderick L., Bernards, René, Ganesan, Trivadi S., Downward, Julian, Hancock, David C.

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The transcriptional response to Raf activation is almost completely dependent on Mitogen-activated Protein Kinase Kinase activity and shows a major autocrine component von Schulze, Almut, Nicke, Barbara, Warne, Patricia H, Tomlinson, Simon, Downward, Julian

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Fibroblast Growth Factor 2-Mediated Translational Control of IAPs Blocks Mitochondrial Release of Smac/DIABLO and Apoptosis in Small Cell Lung Cancer Cells von Pardo, Olivier E., Lesay, Adeline, Arcaro, Alexandre, Lopes, Rita, Ng, Bee Ling, Warne, Patricia H., McNeish, Iain A., Tetley, Teresa D., Lemoine, Nicholas R., Mehmet, Huseyin, Seckl, Michael J., Downward, Julian

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p110δ , a Novel Phosphoinositide 3-Kinase in Leukocytes von Vanhaesebroeck, Bart, Welham, Melanie J., Kotani, Kei, Stein, Rob, Warne, Patricia H., Zvelebil, Marketa J., Higashi, Kyoichiro, Volinia, Stefano, Downward, Julian, Waterfield, Michael D.

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