The discovery of a potent Nav1.3 inhibitor with good oral pharmacokinetics von Pryde, D C, Swain, NA, Stupple, P A, West, C W, Marron, B, Markworth, C J, Printzenhoff, D, Lin, Z, Cox, P J, Suzuki, R, McMurray, S, Waldron, G J, Payne, CE, Warmus, J S, Chapman, M L

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The discovery of a potent Na v 1.3 inhibitor with good oral pharmacokinetics von Pryde, D C, Swain, N A, Stupple, P A, West, C W, Marron, B, Markworth, C J, Printzenhoff, D, Lin, Z, Cox, P J, Suzuki, R, McMurray, S, Waldron, G J, Payne, C E, Warmus, J S, Chapman, M L

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A Novel Nonpeptide HIV-1 Protease Inhibitor: Elucidation of the Binding Mode and Its Application in the Design of Related Analogs von Lunney, Elizabeth A, Hagen, Susan E, Domagala, John M, Humblet, Christine, Kosinski, Janet, Tait, Bradley D, Warmus, Joseph S, Wilson, Michael, Ferguson, Donna

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Characterization of the Antiviral Activity of Highly Substituted Pyrroles: A Novel Class of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitor von Antonucci, T., Warmus, J. S., Hodges, J. C., Nickell, D. G.

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Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain von Bagal, Sharan K, Andrews, Mark, Bechle, Bruce M, Bian, Jianwei, Bilsland, James, Blakemore, David C, Braganza, John F, Bungay, Peter J, Corbett, Matthew S, Cronin, Ciaran N, Cui, Jingrong Jean, Dias, Rebecca, Flanagan, Neil J, Greasley, Samantha E, Grimley, Rachel, James, Kim, Johnson, Eric, Kitching, Linda, Kraus, Michelle L, McAlpine, Indrawan, Nagata, Asako, Ninkovic, Sacha, Omoto, Kiyoyuki, Scales, Stephanie, Skerratt, Sarah E, Sun, Jianmin, Tran-Dubé, Michelle, Waldron, Gareth J, Wang, Fen, Warmus, Joseph S

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Integrating combinatorial chemistry into the discovery pipeline von Warmus, Joseph S

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Rapid optimization of an ice inhibitor synthesis using multiple reaction conditions in a parallel array von Warmus, Joseph S., Ryder, Todd R., Hodges, John C., Kennedy, Robert M., Brady, Kenneth D.

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The discovery of a potent Nav1.3 inhibitor with good oral pharmacokineticsAll authors are, or were at the time of the work being undertaken, employees of Pfizer von Pryde, D. C, Swain, N. A, Stupple, P. A, West, C. W, Marron, B, Markworth, C. J, Printzenhoff, D, Lin, Z, Cox, P. J, Suzuki, R, McMurray, S, Waldron, G. J, Payne, C. E, Warmus, J. S, Chapman, M. L

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The discovery of a potent Nav1.3 inhibitor with good oral pharmacokinetics† †All authors are, or were at the time of the work being undertaken, employees of Pfizer von Pryde, D. C., Swain, N. A., Stupple, P. A., West, C. W., Marron, B., Markworth, C. J., Printzenhoff, D., Lin, Z., Cox, P. J., Suzuki, R., McMurray, S., Waldron, G. J., Payne, C. E., Warmus, J. S., Chapman, M. L.

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Chiral lithio formamidines. Are they configurationally stable? von Meyers, A.I., Guiles, Joseph, Warmus, Joseph S., Gonzalez, Michael A.

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Synthesis and transannular diels-alder reactions of (E,E,E)-cyclotetradeca-2,8,10-trienones von Roush, William R., Warmus, Joseph S., Works, Andrea B.

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A modified procedure for the preparation of 2,5-dihydropyrrole (3-pyrroline) von Warmus, Joseph S, Dilley, Garrett J, Meyers, A. I

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Discovery and optimisation of potent and highly subtype selective Nav1.8 inhibitors with reduced cardiovascular liabilities von Bagal, Sharan K, Kemp, Mark I, Bungay, Peter J, Hay, Tanya L, Murata, Yoshihisa, Payne, CElizabeth, Stevens, Edward B, Brown, Alan, Blakemore, David C, Corbett, Matthew S, Miller, Duncan C, Omoto, Kiyoyuki, Warmus, Joseph S

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Chiral formamidines. Asymmetric synthesis of 1,1-disubstituted tetrahydroisoquinolines von Meyers, A.I., Gonzalez, Michael A., Struzka, Vladimir, Akahane, Atsushi, Guiles, Joseph, Warmus, Joseph S.

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Synthesis and Diels-Alder reactions of 2-alkyl-5-methylene-1,3-dioxolan-4-ones and 2-alkyl-3-acyl-5-methylene-1,3-oxazolidin-4-ones: Highly exo and diastereoface selective chiral k... von Roush, William R., Essenfeld, Amy P., Warmus, Joseph S., Brown, Bradley B.

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Effect of dienophile activating group on the stereoselectivity of the intramolecular diels-alder reaction von Roush, William R, Essenfeld, Amy P, Warmus, Joseph S

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Polyaromatic Scavenger Reagents (PAHSR):  A New Methodology for Rapid Purification in Solution-Phase Combinatorial Synthesis von Warmus, Joseph S, da Silva, Marianne I

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Rapid optimization of an ice inhibitor synthesis using multiple reaction conditions in a parallel array: Combinatorial chemistry von WARMUS, J. S, RYDER, T. R, HODGES, J. C, KENNEDY, R. M, BRADY, K. D

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Kinetic isotope effects in the deprotonation of chiral formamidines von WARMUS, J. S, RODKIN, M. A, BARKLEY, R, MEYERS, A. I

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Chiral formamidines. The mechanism of mono- and di-alkylation leading to chiral, non-racemic tetrahydroisoquinolines von Meyers, A.I., Warmus, Joseph S., Gonzalez, Michael A., Guiles, Joseph, Akahane, Atsushi

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