The discovery of a potent Nav1.3 inhibitor with good oral pharmacokinetics von Pryde, D C, Swain, NA, Stupple, P A, West, C W, Marron, B, Markworth, C J, Printzenhoff, D, Lin, Z, Cox, P J, Suzuki, R, McMurray, S, Waldron, G J, Payne, CE, Warmus, J S, Chapman, M L

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The discovery of a potent Na v 1.3 inhibitor with good oral pharmacokinetics von Pryde, D C, Swain, N A, Stupple, P A, West, C W, Marron, B, Markworth, C J, Printzenhoff, D, Lin, Z, Cox, P J, Suzuki, R, McMurray, S, Waldron, G J, Payne, C E, Warmus, J S, Chapman, M L

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The discovery of a potent series of carboxamide TRPA1 antagonists von Pryde, D. C., Marron, B., West, C. G., Reister, S., Amato, G., Yoger, K., Padilla, K., Turner, J., Swain, N. A., Cox, P. J., Skerratt, S. E., Ryckmans, T., Blakemore, D. C., Warmus, J., Gerlach, A. C.

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Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition von Hasemann, Charles A, Ohren, Jeffrey F, Chen, Huifen, Pavlovsky, Alexander, Whitehead, Christopher, Zhang, Erli, Kuffa, Peter, Yan, Chunhong, McConnell, Patrick, Spessard, Cindy, Banotai, Craig, Mueller, W Thomas, Delaney, Amy, Omer, Charles, Sebolt-Leopold, Judith, Dudley, David T, Leung, Iris K, Flamme, Cathlin, Warmus, Joseph, Kaufman, Michael, Barrett, Stephen, Tecle, Haile

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OA 04.01 Randomized Trial of Systematic Lymph Node Dissection versus Bilateral Mediastinal Lymphadenectomy in Patients with Non-Small Cell Carcinoma von Kuzdzal, J., Hauer, Ł., Hauer, J., Warmus, J., Kocon, P., Trybalski, Ł., Grochowski, Z., Włodarczyk, J., Gil, T., Smęder, T.

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A Novel Nonpeptide HIV-1 Protease Inhibitor: Elucidation of the Binding Mode and Its Application in the Design of Related Analogs von Lunney, Elizabeth A, Hagen, Susan E, Domagala, John M, Humblet, Christine, Kosinski, Janet, Tait, Bradley D, Warmus, Joseph S, Wilson, Michael, Ferguson, Donna

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P2.17-11 Impact of Quantitatively Assessed Emphysema on Chest Tube Drainage After Lobectomy for Non-Small Cell Lung Cancer von Gil, T., Grochowski, Z., Warmus, J., Bederski, K., Kocoń, P., Włodarczyk, J., Trybalski, Ł., Smęder, T., Żanowska, K., Hajder, P., Kołodziejczyk, B., Cieślak, W., Kużdżał, J., Banyś, R.

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Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain von Bagal, Sharan K, Andrews, Mark, Bechle, Bruce M, Bian, Jianwei, Bilsland, James, Blakemore, David C, Braganza, John F, Bungay, Peter J, Corbett, Matthew S, Cronin, Ciaran N, Cui, Jingrong Jean, Dias, Rebecca, Flanagan, Neil J, Greasley, Samantha E, Grimley, Rachel, James, Kim, Johnson, Eric, Kitching, Linda, Kraus, Michelle L, McAlpine, Indrawan, Nagata, Asako, Ninkovic, Sacha, Omoto, Kiyoyuki, Scales, Stephanie, Skerratt, Sarah E, Sun, Jianmin, Tran-Dubé, Michelle, Waldron, Gareth J, Wang, Fen, Warmus, Joseph S

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P2.16-027 Comparison of Single Chest Tube Versus Double Chest Tube Drainage After Lung Resection for the Treatment of Non-Small Cell Lung Cancer von Gil, T., Grochowski, Z., Warmus, J., Gocyk, W., Staniec, B., Bederski, K., Kocoń, P., Włodarczyk, J., Hajder, P., Kołodziejczyk, B., Kużdżał, J.

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Double stenting for malignant airway and esophageal obstructions von Włodarczyk, J., Gil, T., Warmus, J., Grochowski, Z., Gocyk, W., Kocoń, P., Talar, P., Smęder, T., Kużdżał, J.

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Giant oesophageal polyp prolapse von W odarczyk, Janusz, Warmus, Janusz, Gocyk, Wojciech, Ku d a, Jaros aw

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Integrating combinatorial chemistry into the discovery pipeline von Warmus, Joseph S

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F-090 MINIMALLY INVASIVE STRATEGY OF MEDIASTINAL STAGING OF LUNG CANCER von Hauer, J., Trybalski, L., Szlubowski, A., Kocon, P., Talar, P., Warmus, J., Kuzdzal, J.

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F-090MINIMALLY INVASIVE STRATEGY OF MEDIASTINAL STAGING OF LUNG CANCER von Hauer, J., Trybalski, L., Szlubowski, A., Kocon, P., Talar, P., Warmus, J., Kuzdzal, Jaroslaw

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The discovery of a potent Nav1.3 inhibitor with good oral pharmacokineticsAll authors are, or were at the time of the work being undertaken, employees of Pfizer von Pryde, D. C, Swain, N. A, Stupple, P. A, West, C. W, Marron, B, Markworth, C. J, Printzenhoff, D, Lin, Z, Cox, P. J, Suzuki, R, McMurray, S, Waldron, G. J, Payne, C. E, Warmus, J. S, Chapman, M. L

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The discovery of a potent Nav1.3 inhibitor with good oral pharmacokinetics† †All authors are, or were at the time of the work being undertaken, employees of Pfizer von Pryde, D. C., Swain, N. A., Stupple, P. A., West, C. W., Marron, B., Markworth, C. J., Printzenhoff, D., Lin, Z., Cox, P. J., Suzuki, R., McMurray, S., Waldron, G. J., Payne, C. E., Warmus, J. S., Chapman, M. L.

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The discovery of a potent series of carboxamide TRPA1 antagonistsAll authors are either current or former employees of Pfizer.Electronic supplementary information (ESI) available:... von Pryde, D. C, Marron, B, West, C. G, Reister, S, Amato, G, Yoger, K, Padilla, K, Turner, J, Swain, N. A, Cox, P. J, Skerratt, S. E, Ryckmans, T, Blakemore, D. C, Warmus, J, Gerlach, A. C

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Rapid optimization of an ice inhibitor synthesis using multiple reaction conditions in a parallel array von Warmus, Joseph S., Ryder, Todd R., Hodges, John C., Kennedy, Robert M., Brady, Kenneth D.

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Discovery and optimisation of potent and highly subtype selective Nav1.8 inhibitors with reduced cardiovascular liabilities von Bagal, Sharan K, Kemp, Mark I, Bungay, Peter J, Hay, Tanya L, Murata, Yoshihisa, Payne, CElizabeth, Stevens, Edward B, Brown, Alan, Blakemore, David C, Corbett, Matthew S, Miller, Duncan C, Omoto, Kiyoyuki, Warmus, Joseph S

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Characterization of the Antiviral Activity of Highly Substituted Pyrroles: A Novel Class of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitor von Antonucci, T., Warmus, J. S., Hodges, J. C., Nickell, D. G.

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