Pre-diagnostic meat and fibre intakes in relation to colorectal cancer survival in the European Prospective Investigation into Cancer and Nutrition von Ward, Heather A, Norat, Teresa, Overvad, Kim, Dahm, Christina C, Bueno-de-Mesquita, H Bas, Jenab, Mazda, Fedirko, Veronika, van, Duijnhoven Fränzel JB, Skeie, Guri, Romaguera-Bosch, Dora, Tjønneland, Anne, Olsen, Anja, Carbonnel, Franck, Affret, Aurélie, Boutron-Ruault, Marie-Christine, Katzke, Verena, Kühn, Tilman, Aleksandrova, Krassimira, Boeing, Heiner, Trichopoulou, Antonia, Lagiou, Pagona, Bamia, Christina, Palli, Domenico, Sieri, Sabina, Tumino, Rosario, Naccarati, Alessio, Mattiello, Amalia, Peeters, Petra H, Weiderpass, Elisabete, Åsli, Lene Angell, Jakszyn, Paula, Quirós, J Ramón, Sánchez, María-José, Dorronsoro, Miren, Huerta, José-María, Barricarte, Aurelio, Jirström, Karin, Ericson, Ulrika, Johansson, Ingegerd, Gylling, Björn, Bradbury, Kathryn E, Khaw, Kay-Tee, Wareham, Nicholas John, Stepien, Magdalena, Freisling, Heinz, Murphy, Neil, Cross, Amanda J, Riboli, Elio

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Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity von Lotta, Luca A., Mokrosiński, Jacek, Mendes de Oliveira, Edson, Li, Chen, Sharp, Stephen J., Luan, Jian’an, Brouwers, Bas, Ayinampudi, Vikram, Bowker, Nicholas, Kerrison, Nicola, Kaimakis, Vasileios, Hoult, Diana, Stewart, Isobel D., Wheeler, Eleanor, Day, Felix R., Perry, John R.B., Langenberg, Claudia, Wareham, Nicholas J., Farooqi, I. Sadaf

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Mothers after Gestational Diabetes in Australia (MAGDA): A Randomised Controlled Trial of a Postnatal Diabetes Prevention Program von O'Reilly, Sharleen L, Dunbar, James A, Versace, Vincent, Janus, Edward, Best, James D, Carter, Rob, Oats, Jeremy J N, Skinner, Timothy, Ackland, Michael, Phillips, Paddy A, Ebeling, Peter R, Reynolds, John, Shih, Sophy T F, Hagger, Virginia, Coates, Michael, Wildey, Carol

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Supported Telemonitoring and Glycemic Control in People with Type 2 Diabetes: The Telescot Diabetes Pragmatic Multicenter Randomized Controlled Trial von Wild, Sarah H, Hanley, Janet, Lewis, Stephanie C, McKnight, John A, McCloughan, Lucy B, Padfield, Paul L, Parker, Richard A, Paterson, Mary, Pinnock, Hilary, Sheikh, Aziz, McKinstry, Brian

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Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study von Li, Shengxu, Zhao, Jing Hua, Luan, Jian'an, Ekelund, Ulf, Luben, Robert N, Khaw, Kay-Tee, Wareham, Nicholas J, Loos, Ruth J F

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Using human genetics to understand the disease impacts of testosterone in men and women von Ruth, Katherine S, Day, Felix R, Tyrrell, Jessica, Thompson, Deborah J, Wood, Andrew R, Mahajan, Anubha, Beaumont, Robin N, Wittemans, Laura, Martin, Susan, Busch, Alexander S., Erzurumluoglu, A. Mesut, Hollis, Benjamin, O’Mara, Tracy A., McCarthy, Mark I, Langenberg, Claudia, Easton, Douglas F, Wareham, Nicholas J, Burgess, Stephen, Murray, Anna, Ong, Ken K, Frayling, Timothy M, Perry, John R. B.

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GDF15 mediates the effects of metformin on body weight and energy balance von Coll, Anthony P., Chen, Michael, Taskar, Pranali, Rimmington, Debra, Patel, Satish, Tadross, John A., Cimino, Irene, Yang, Ming, Welsh, Paul, Virtue, Samuel, Goldspink, Deborah A., Miedzybrodzka, Emily L., Konopka, Adam R., Esponda, Raul Ruiz, Huang, Jeffrey T.-J., Tung, Y. C. Loraine, Rodriguez-Cuenca, Sergio, Tomaz, Rute A., Harding, Heather P., Melvin, Audrey, Yeo, Giles S. H., Preiss, David, Vidal-Puig, Antonio, Vallier, Ludovic, Nair, K. Sreekumaran, Wareham, Nicholas J., Ron, David, Gribble, Fiona M., Reimann, Frank, Sattar, Naveed, Savage, David B., Allan, Bernard B., O’Rahilly, Stephen

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A cross-platform approach identifies genetic regulators of human metabolism and health von Lotta, Luca A., Pietzner, Maik, Stewart, Isobel D., Wittemans, Laura B. L., Li, Chen, Bonelli, Roberto, Raffler, Johannes, Biggs, Emma K., Oliver-Williams, Clare, Auyeung, Victoria P. W., Luan, Jian’an, Wheeler, Eleanor, Paige, Ellie, Surendran, Praveen, Michelotti, Gregory A., Scott, Robert A., Burgess, Stephen, Zuber, Verena, Sanderson, Eleanor, Koulman, Albert, Imamura, Fumiaki, Forouhi, Nita G., Khaw, Kay-Tee, Griffin, Julian L., Wood, Angela M., Kastenmüller, Gabi, Danesh, John, Butterworth, Adam S., Gribble, Fiona M., Reimann, Frank, Bahlo, Melanie, Fauman, Eric, Wareham, Nicholas J., Langenberg, Claudia

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Causal associations between cardiorespiratory fitness and type 2 diabetes von Cai, Lina, Gonzales, Tomas, Wheeler, Eleanor, Kerrison, Nicola D., Day, Felix R., Langenberg, Claudia, Perry, John R. B., Brage, Soren, Wareham, Nicholas J.

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Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene von Kentistou, Katherine A., Luan, Jian’an, Wittemans, Laura B. L., Hambly, Catherine, Klaric, Lucija, Kutalik, Zoltán, Speakman, John R., Wareham, Nicholas J., Kendall, Timothy J., Langenberg, Claudia, Wilson, James F., Joshi, Peter K., Morton, Nicholas M.

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Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors von Lotta, Luca A, Wittemans, Laura B. L, Zuber, Verena, Stewart, Isobel D, Sharp, Stephen J, Luan, Jian’an, Day, Felix R, Li, Chen, Bowker, Nicholas, Cai, Lina, De Lucia Rolfe, Emanuella, Khaw, Kay-Tee, Perry, John R. B, O’Rahilly, Stephen, Scott, Robert A, Savage, David B, Burgess, Stephen, Wareham, Nicholas J, Langenberg, Claudia

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Assessing the causal association of glycine with risk of cardio-metabolic diseases von Wittemans, Laura B. L., Lotta, Luca A., Oliver-Williams, Clare, Stewart, Isobel D., Surendran, Praveen, Karthikeyan, Savita, Day, Felix R., Koulman, Albert, Imamura, Fumiaki, Zeng, Lingyao, Erdmann, Jeanette, Schunkert, Heribert, Khaw, Kay-Tee, Griffin, Julian L., Forouhi, Nita G., Scott, Robert A., Wood, Angela M., Burgess, Stephen, Howson, Joanna M. M., Danesh, John, Wareham, Nicholas J., Butterworth, Adam S., Langenberg, Claudia

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Rare and common genetic determinants of metabolic individuality and their effects on human health von Surendran, Praveen, Stewart, Isobel D., Au Yeung, Victoria P. W., Pietzner, Maik, Raffler, Johannes, Wörheide, Maria A., Li, Chen, Smith, Rebecca F., Wittemans, Laura B. L., Bomba, Lorenzo, Menni, Cristina, Zierer, Jonas, Rossi, Niccolò, Sheridan, Patricia A., Watkins, Nicholas A., Mangino, Massimo, Hysi, Pirro G., Di Angelantonio, Emanuele, Falchi, Mario, Spector, Tim D., Soranzo, Nicole, Michelotti, Gregory A., Arlt, Wiebke, Lotta, Luca A., Denaxas, Spiros, Hemingway, Harry, Gamazon, Eric R., Howson, Joanna M. M., Wood, Angela M., Danesh, John, Wareham, Nicholas J., Kastenmüller, Gabi, Fauman, Eric B., Suhre, Karsten, Butterworth, Adam S., Langenberg, Claudia

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Evidence of a Causal Association Between Insulinemia and Endometrial Cancer: A Mendelian Randomization Analysis von Nead, Kevin T, Sharp, Stephen J, Thompson, Deborah J, Painter, Jodie N, Savage, David B, Semple, Robert K, Barker, Adam, Perry, John R B, Attia, John, Dunning, Alison M, Easton, Douglas F, Holliday, Elizabeth, Lotta, Luca A, O'Mara, Tracy, McEvoy, Mark, Pharoah, Paul D P, Scott, Rodney J, Spurdle, Amanda B, Langenberg, Claudia, Wareham, Nicholas J, Scott, Robert A

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Oxidation-Specific Biomarkers, Lipoprotein(a), and Risk of Fatal and Nonfatal Coronary Events von Tsimikas, Sotirios, MD, Mallat, Ziad, MD, PhD, Talmud, Philippa J., DSc, Kastelein, John J.P., MD, PhD, Wareham, Nicholas J., MBBS, PhD, Sandhu, Manjinder S., PhD, Miller, Elizabeth R., BS, Benessiano, Joelle, MD, PhD, Tedgui, Alain, PhD, Witztum, Joseph L., MD, Khaw, Kay-Tee, MBBChir, Boekholdt, S. Matthijs, MD, PhD

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GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health von Zhao, Yajie, Stankovic, Stasa, Koprulu, Mine, Wheeler, Eleanor, Day, Felix R., Lango Allen, Hana, Kerrison, Nicola D., Pietzner, Maik, Loh, Po-Ru, Wareham, Nicholas J., Langenberg, Claudia, Ong, Ken K., Perry, John R. B.

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Association Between Low-Density Lipoprotein Cholesterol–Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis von Lotta, Luca A, Sharp, Stephen J, Burgess, Stephen, Perry, John R. B, Stewart, Isobel D, Willems, Sara M, Luan, Jian’an, Ardanaz, Eva, Arriola, Larraitz, Balkau, Beverley, Boeing, Heiner, Deloukas, Panos, Forouhi, Nita G, Franks, Paul W, Grioni, Sara, Kaaks, Rudolf, Key, Timothy J, Navarro, Carmen, Nilsson, Peter M, Overvad, Kim, Palli, Domenico, Panico, Salvatore, Quirós, Jose-Ramón, Riboli, Elio, Rolandsson, Olov, Sacerdote, Carlotta, Salamanca-Fernandez, Elena, Slimani, Nadia, Spijkerman, Annemieke M. W, Tjonneland, Anne, Tumino, Rosario, van der A, Daphne L, van der Schouw, Yvonne T, McCarthy, Mark I, Barroso, Inês, O’Rahilly, Stephen, Savage, David B, Sattar, Naveed, Langenberg, Claudia, Scott, Robert A, Wareham, Nicholas J

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Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis von Benyamin, Beben, Esko, Tonu, Ried, Janina S., Radhakrishnan, Aparna, Vermeulen, Sita H., Traglia, Michela, Gögele, Martin, Anderson, Denise, Broer, Linda, Podmore, Clara, Luan, Jian’an, Kutalik, Zoltan, Sanna, Serena, van der Meer, Peter, Tanaka, Toshiko, Wang, Fudi, Westra, Harm-Jan, Franke, Lude, Mihailov, Evelin, Milani, Lili, Hälldin, Jonas, Winkelmann, Juliane, Meitinger, Thomas, Thiery, Joachim, Peters, Annette, Waldenberger, Melanie, Rendon, Augusto, Jolley, Jennifer, Sambrook, Jennifer, Kiemeney, Lambertus A., Sweep, Fred C., Sala, Cinzia F., Schwienbacher, Christine, Pichler, Irene, Hui, Jennie, Demirkan, Ayse, Isaacs, Aaron, Amin, Najaf, Steri, Maristella, Waeber, Gérard, Verweij, Niek, Powell, Joseph E., Nyholt, Dale R., Heath, Andrew C., Madden, Pamela A. F., Visscher, Peter M., Wright, Margaret J., Montgomery, Grant W., Martin, Nicholas G., Hernandez, Dena, Bandinelli, Stefania, van der Harst, Pim, Uda, Manuela, Vollenweider, Peter, Scott, Robert A., Langenberg, Claudia, Wareham, Nicholas J., van Duijn, Cornelia, Beilby, John, Pramstaller, Peter P., Hicks, Andrew A., Ouwehand, Willem H., Oexle, Konrad, Gieger, Christian, Metspalu, Andres, Camaschella, Clara, Toniolo, Daniela, Swinkels, Dorine W., Whitfield, John B.

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Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome von Day, Felix R., Hinds, David A., Tung, Joyce Y., Stolk, Lisette, Styrkarsdottir, Unnur, Saxena, Richa, Bjonnes, Andrew, Broer, Linda, Dunger, David B., Halldorsson, Bjarni V., Lawlor, Debbie A., Laval, Guillaume, Mathieson, Iain, McCardle, Wendy L., Louwers, Yvonne, Meun, Cindy, Ring, Susan, Scott, Robert A., Sulem, Patrick, Uitterlinden, André G., Wareham, Nicholas J., Thorsteinsdottir, Unnur, Welt, Corrine, Stefansson, Kari, Laven, Joop S. E., Ong, Ken K., Perry, John R. B.

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Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension von Padmanabhan, Sandosh, Melander, Olle, Johnson, Toby, Di Blasio, Anna Maria, Lee, Wai K, Gentilini, Davide, Hastie, Claire E, Menni, Cristina, Monti, Maria Cristina, Delles, Christian, Laing, Stewart, Corso, Barbara, Navis, Gerjan, Kwakernaak, Arjan J, van der Harst, Pim, Bochud, Murielle, Maillard, Marc, Burnier, Michel, Hedner, Thomas, Kjeldsen, Sverre, Wahlstrand, Björn, Sjögren, Marketa, Fava, Cristiano, Montagnana, Martina, Danese, Elisa, Torffvit, Ole, Hedblad, Bo, Snieder, Harold, Connell, John M C, Brown, Morris, Samani, Nilesh J, Farrall, Martin, Cesana, Giancarlo, Mancia, Giuseppe, Signorini, Stefano, Grassi, Guido, Eyheramendy, Susana, Wichmann, H Erich, Laan, Maris, Strachan, David P, Sever, Peter, Shields, Denis Colm, Stanton, Alice, Vollenweider, Peter, Teumer, Alexander, Völzke, Henry, Rettig, Rainer, Newton-Cheh, Christopher, Arora, Pankaj, Zhang, Feng, Soranzo, Nicole, Spector, Timothy D, Lucas, Gavin, Kathiresan, Sekar, Siscovick, David S, Luan, Jian'an, Loos, Ruth J F, Wareham, Nicholas J, Penninx, Brenda W, Nolte, Ilja M, McBride, Martin, Miller, William H, Nicklin, Stuart A, Baker, Andrew H, Graham, Delyth, McDonald, Robert A, Pell, Jill P, Sattar, Naveed, Welsh, Paul, Munroe, Patricia, Caulfield, Mark J, Zanchetti, Alberto, Dominiczak, Anna F

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