Implementation of a fully integrated continuous manufacturing line for direct compression and coating at a commercial pharmaceutical facility – Part 1: Operational considerations a... von Conway, Stephen L., Rosas, Juan G., Overton, Paul, Tugby, Neil, Cryan, Phillip, Witulski, Frank, Hurley, Samantha, Wareham, Laura, Tantuccio, Anthony, Ramasamy, Manoharan, Lalloo, Anita, Gibbs, Mason, Meyer, Robert F.

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Validating a Numerical Simulation of the ConsiGma(R) Coater von Boehling, Peter, Jacevic, Dalibor, Detobel, Frederik, Holman, James, Wareham, Laura, Metzger, Matthew, Khinast, Johannes G.

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Optimization of Critical Quality Attributes in Tablet Film Coating and Design Space Determination Using Pilot-Scale Experimental Data von Liu, Huolong, Meyer, Robert, Flamm, Matthew, Wareham, Laura, Metzger, Matthew, Tantuccio, Anthony, Yoon, Seongkyu

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High Bulk-Density Amorphous Dispersions to Enable Direct Compression of Reduced Tablet Size Amorphous Dosage Units von Frank, Derek S., Nie, Haichen, Chandra, Anagha, Coelho, Alexander, Dalton, Chad, Dvorak, Hannah, Elkhabaz, Ahmed, Fahy, Mairead, Ormes, James, Parker, Andrew, Punia, Ashish, Rowe, Jasmine, Schenck, Luke, Smith, Daniel, Strotman, Neil A., Wang, Michael, Wareham, Laura

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A cross-platform approach identifies genetic regulators of human metabolism and health von Lotta, Luca A., Pietzner, Maik, Stewart, Isobel D., Wittemans, Laura B. L., Li, Chen, Bonelli, Roberto, Raffler, Johannes, Biggs, Emma K., Oliver-Williams, Clare, Auyeung, Victoria P. W., Luan, Jian’an, Wheeler, Eleanor, Paige, Ellie, Surendran, Praveen, Michelotti, Gregory A., Scott, Robert A., Burgess, Stephen, Zuber, Verena, Sanderson, Eleanor, Koulman, Albert, Imamura, Fumiaki, Forouhi, Nita G., Khaw, Kay-Tee, Griffin, Julian L., Wood, Angela M., Kastenmüller, Gabi, Danesh, John, Butterworth, Adam S., Gribble, Fiona M., Reimann, Frank, Bahlo, Melanie, Fauman, Eric, Wareham, Nicholas J., Langenberg, Claudia

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Assessing the causal association of glycine with risk of cardio-metabolic diseases von Wittemans, Laura B. L., Lotta, Luca A., Oliver-Williams, Clare, Stewart, Isobel D., Surendran, Praveen, Karthikeyan, Savita, Day, Felix R., Koulman, Albert, Imamura, Fumiaki, Zeng, Lingyao, Erdmann, Jeanette, Schunkert, Heribert, Khaw, Kay-Tee, Griffin, Julian L., Forouhi, Nita G., Scott, Robert A., Wood, Angela M., Burgess, Stephen, Howson, Joanna M. M., Danesh, John, Wareham, Nicholas J., Butterworth, Adam S., Langenberg, Claudia

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KSR2 Mutations Are Associated with Obesity, Insulin Resistance, and Impaired Cellular Fuel Oxidation von Pearce, Laura R., Atanassova, Neli, Banton, Matthew C., Bottomley, Bill, van der Klaauw, Agatha A., Revelli, Jean-Pierre, Hendricks, Audrey, Keogh, Julia M., Henning, Elana, Doree, Deon, Jeter-Jones, Sabrina, Garg, Sumedha, Bochukova, Elena G., Bounds, Rebecca, Ashford, Sofie, Gayton, Emma, Hindmarsh, Peter C., Shield, Julian P.H., Crowne, Elizabeth, Barford, David, Wareham, Nick J., O’Rahilly, Stephen, Murphy, Michael P., Powell, David R., Barroso, Ines, Farooqi, I. Sadaf

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Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors von Lotta, Luca A, Wittemans, Laura B. L, Zuber, Verena, Stewart, Isobel D, Sharp, Stephen J, Luan, Jian’an, Day, Felix R, Li, Chen, Bowker, Nicholas, Cai, Lina, De Lucia Rolfe, Emanuella, Khaw, Kay-Tee, Perry, John R. B, O’Rahilly, Stephen, Scott, Robert A, Savage, David B, Burgess, Stephen, Wareham, Nicholas J, Langenberg, Claudia

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Regional fat depot masses are influenced by protein-coding gene variants von Neville, Matt J, Wittemans, Laura B L, Pinnick, Katherine E, Todorčević, Marijana, Kaksonen, Risto, Pietiläinen, Kirsi H, Luan, Jian'an, Scott, Robert A, Wareham, Nicholas J, Langenberg, Claudia, Karpe, Fredrik

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Engagement, Retention, and Progression to Type 2 Diabetes: A Retrospective Analysis of the Cluster-Randomised "Let's Prevent Diabetes" Trial von Gray, Laura J, Yates, Thomas, Troughton, Jacqui, Khunti, Kamlesh, Davies, Melanie J

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Intakes and sources of dietary sugars and their association with metabolic and inflammatory markers von O’Connor, Laura, PhD, Imamura, Fumiaki, MSc PhD, Brage, Soren, MPhil PhD, Griffin, Simon J., PhD, FRCGP, Wareham, Nicholas J., PhD, FRCP, Forouhi, Nita G., PhD FFPHM

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The cross-sectional association between snacking behaviour and measures of adiposity: the Fenland Study, UK von O’Connor, Laura, Brage, Soren, Griffin, Simon J., Wareham, Nicholas J., Forouhi, Nita G.

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Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene von Kentistou, Katherine A., Luan, Jian’an, Wittemans, Laura B. L., Hambly, Catherine, Klaric, Lucija, Kutalik, Zoltán, Speakman, John R., Wareham, Nicholas J., Kendall, Timothy J., Langenberg, Claudia, Wilson, James F., Joshi, Peter K., Morton, Nicholas M.

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Rare and common genetic determinants of metabolic individuality and their effects on human health von Surendran, Praveen, Stewart, Isobel D., Au Yeung, Victoria P. W., Pietzner, Maik, Raffler, Johannes, Wörheide, Maria A., Li, Chen, Smith, Rebecca F., Wittemans, Laura B. L., Bomba, Lorenzo, Menni, Cristina, Zierer, Jonas, Rossi, Niccolò, Sheridan, Patricia A., Watkins, Nicholas A., Mangino, Massimo, Hysi, Pirro G., Di Angelantonio, Emanuele, Falchi, Mario, Spector, Tim D., Soranzo, Nicole, Michelotti, Gregory A., Arlt, Wiebke, Lotta, Luca A., Denaxas, Spiros, Hemingway, Harry, Gamazon, Eric R., Howson, Joanna M. M., Wood, Angela M., Danesh, John, Wareham, Nicholas J., Kastenmüller, Gabi, Fauman, Eric B., Suhre, Karsten, Butterworth, Adam S., Langenberg, Claudia

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Dietary dairy product intake and incident type 2 diabetes: a prospective study using dietary data from a 7-day food diary von O’Connor, Laura M., Lentjes, Marleen A. H., Luben, Robert N., Khaw, Kay-Tee, Wareham, Nicholas J., Forouhi, Nita G.

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Prospective associations and population impact of sweet beverage intake and type 2 diabetes, and effects of substitutions with alternative beverages von O’Connor, Laura, Imamura, Fumiaki, Lentjes, Marleen A. H., Khaw, Kay-Tee, Wareham, Nicholas J., Forouhi, Nita G.

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New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries von Shrine, Nick, Guyatt, Anna L., Erzurumluoglu, A. Mesut, Jackson, Victoria E., Hobbs, Brian D., Melbourne, Carl A., Batini, Chiara, Fawcett, Katherine A., Song, Kijoung, Sakornsakolpat, Phuwanat, Boxall, Ruth, Reeve, Nicola F., Obeidat, Ma’en, Zhao, Jing Hua, Wielscher, Matthias, Weiss, Stefan, Kentistou, Katherine A., Cook, James P., Sun, Benjamin B., Zhou, Jian, Hui, Jennie, Karrasch, Stefan, Imboden, Medea, Harris, Sarah E, Marten, Jonathan, Enroth, Stefan, Kerr, Shona M., Surakka, Ida, Vitart, Veronique, Lehtimäki, Terho, Bakke, Per S., Beaty, Terri H., Bossé, Yohan, Brandsma, Corry-Anke, Chen, Zhengming, Crapo, James D., Danesh, John, DeMeo, Dawn L., Dudbridge, Frank, Gieger, Christian, Gulsvik, Amund, Hansell, Anna L., Hao, Ke, Hoffman, Joshua D., Hokanson, John E., Homuth, Georg, Joshi, Peter K., Joubert, Philippe, Langenberg, Claudia, Li, Xuan, Li, Liming, Lin, Kuang, Lind, Lars, Locantore, Nicholas, Luan, Jian’an, Mahajan, Anubha, Maranville, Joseph C., Murray, Alison, Packer, Richard, Parker, Margaret M., Paynton, Megan L., Porteous, David J., Prokopenko, Dmitry, Runz, Heiko, Sin, Don D, Smith, Blair H, Soler Artigas, María, Sparrow, David, Tal-Singer, Ruth, Timmers, Paul R. H. J., Whittaker, John C., Woodruff, Prescott G., Yerges-Armstrong, Laura M., Troyanskaya, Olga G., Raitakari, Olli T., Kähönen, Mika, Polašek, Ozren, Gyllensten, Ulf, Rudan, Igor, Deary, Ian J., Probst-Hensch, Nicole M., Schulz, Holger, James, Alan L, Wilson, James F., Stubbe, Beate, Zeggini, Eleftheria, Jarvelin, Marjo-Riitta, Wareham, Nick, Silverman, Edwin K., Hayward, Caroline, Morris, Andrew P., Butterworth, Adam S., Scott, Robert A., Walters, Robin G., Meyers, Deborah A., Cho, Michael H., Strachan, David P., Hall, Ian P., Tobin, Martin D., Wain, Louise V.

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A new tool for converting food frequency questionnaire data into nutrient and food group values: FETA research methods and availability von Mulligan, Angela A, Luben, Robert N, Bhaniani, Amit, Parry-Smith, David J, O'Connor, Laura, Khawaja, Anthony P, Forouhi, Nita G, Khaw, Kay-Tee

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Separate and combined associations of obesity and metabolic health with coronary heart disease: a pan-European case-cohort analysis von Lassale, Camille, Tzoulaki, Ioanna, Moons, Karel G M, Sweeting, Michael, Boer, Jolanda, Johnson, Laura, Huerta, José María, Agnoli, Claudia, Freisling, Heinz, Weiderpass, Elisabete, Wennberg, Patrik, van der A, Daphne L, Arriola, Larraitz, Benetou, Vassiliki, Boeing, Heiner, Bonnet, Fabrice, Colorado-Yohar, Sandra M, Engström, Gunnar, Eriksen, Anne K, Ferrari, Pietro, Grioni, Sara, Johansson, Matthias, Kaaks, Rudolf, Katsoulis, Michail, Katzke, Verena, Key, Timothy J, Matullo, Giuseppe, Melander, Olle, Molina-Portillo, Elena, Moreno-Iribas, Concepción, Norberg, Margareta, Overvad, Kim, Panico, Salvatore, Quirós, J Ramón, Saieva, Calogero, Skeie, Guri, Steffen, Annika, Stepien, Magdalena, Tjønneland, Anne, Trichopoulou, Antonia, Tumino, Rosario, van der Schouw, Yvonne T, Verschuren, W M Monique, Langenberg, Claudia, Di Angelantonio, Emanuele, Riboli, Elio, Wareham, Nicholas J, Danesh, John, Butterworth, Adam S

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Insights into genetic variants associated with NASH-fibrosis from metabolite profiling von Mann, Jake P, Pietzner, Maik, Wittemans, Laura B, Rolfe, Emmanuela De Lucia, Kerrison, Nicola D, Imamura, Fumiaki, Forouhi, Nita G, Fauman, Eric, Allison, Michael E, Griffin, Jules L, Koulman, Albert, Wareham, Nicholas J, Langenberg, Claudia

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