Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1 von Rudan Njavro, Jasenka, Klotz, Jakob, Dislich, Bastian, Wanngren, Johanna, Shmueli, Merav D., Herber, Julia, Kuhn, Peer‐Hendrik, Kumar, Rohit, Koeglsperger, Thomas, Conrad, Marcus, Wurst, Wolfgang, Feederle, Regina, Vlachos, Andreas, Michalakis, Stylianos, Jedlicka, Peter, Müller, Stephan A., Lichtenthaler, Stefan F.

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γ‐Secretase modulators show selectivity for γ‐secretase–mediated amyloid precursor protein intramembrane processing von Weber, Tobias A., Lundkvist, Johan, Wanngren, Johanna, Kvartsberg, Hlin, Jin, ShaoBo, Larssen, Pia, Wu, Dan, Oliveira, Daniel V., Minta, Karolina, Brinkmalm, Gunnar, Zetterberg, Henrik, Blennow, Kaj, Nordvall, Gunnar, Winblad, Bengt, Portelius, Erik, Karlström, Helena

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Second Generation γ-Secretase Modulators Exhibit Different Modulation of Notch β and Aβ Production von Wanngren, Johanna, Ottervald, Jan, Parpal, Santiago, Portelius, Erik, Strömberg, Kia, Borgegård, Tomas, Klintenberg, Rebecka, Juréus, Anders, Blomqvist, Jenny, Blennow, Kaj, Zetterberg, Henrik, Lundkvist, Johan, Rosqvist, Susanne, Karlström, Helena

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Mutations in Nicastrin Protein Differentially Affect Amyloid β-Peptide Production and Notch Protein Processing von Pamrén, Annelie, Wanngren, Johanna, Tjernberg, Lars O., Winblad, Bengt, Bhat, Ratan, Näslund, Jan, Karlström, Helena

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Changed membrane integration and catalytic site conformation are two mechanisms behind the increased Aβ42/Aβ40 ratio by presenilin 1 familial Alzheimer-linked mutations von Wanngren, Johanna, Lara, Patricia, Öjemalm, Karin, Maioli, Silvia, Moradi, Nasim, Chen, Lu, Tjernberg, Lars O., Lundkvist, Johan, Nilsson, IngMarie, Karlström, Helena

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The large hydrophilic loop of presenilin 1 is important for regulating gamma-secretase complex assembly and dictating the amyloid beta peptide (Abeta) Profile without affecting Not... von Wanngren, J, Frånberg, J, Svensson, A I, Laudon, H, Olsson, F, Winblad, B, Liu, F, Näslund, J, Lundkvist, J, Karlström, H

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The Large Hydrophilic Loop of Presenilin 1 Is Important for Regulating β-Secretase Complex Assembly and Dictating the Amyloid β Peptide (Aβ) Profile without Affecting Notch Process... von Wanngren, J, Franberg, J, Svensson, AI, Laudon, H, Olsson, F, Winblad, B, Liu, F, Naslund, J, Lundkvist, J, Karlstrom, H

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γ-Secretase modulators show selectivity for γ-secretase–mediated amyloid precursor protein intramembrane processing von Weber, TA, Lundkvist, J, Wanngren, J, Kvartsberg, H, Jin, S, Larssen, P, Wu, D, Oliveira, DV, Minta, K, Brinkmalm, G, Zetterberg, H, Blennow, K, Nordvall, G, Winblad, B, Portelius, E, Karlström, H

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Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons von Pigoni, M, Wanngren, J, Kuhn, P-H, Munro, KM, Gunnersen, JM, Takeshima, H, Feederle, R, Voytyuk, I, De Strooper, B, Levasseur, MD, Hrupka, BJ, Mueller, SA, Lichtenthaler, SF

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Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons von Pigoni, Martina, Wanngren, Johanna, Kuhn, Peer-Hendrik, Munro, Kathryn M, Gunnersen, Jenny M, Takeshima, Hiroshi, Feederle, Regina, Voytyuk, Iryna, De Strooper, Bart, Levasseur, Mikail D, Hrupka, Brian J, Müller, Stephan A, Lichtenthaler, Stefan F

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Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons von Pigoni, Martina, Wanngren, Johanna, Kuhn, Peer-Hendrik, Munro, Kathryn M, Gunnersen, Jenny M, Takeshima, Hiroshi, Feederle, Regina, Voytyuk, Iryna, De Strooper, Bart, Levasseur, Mikail D, Hrupka, Brian J, Müller, Stephan A, Lichtenthaler, Stefan F

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