Prediction of biomarkers and therapeutic combinations for anti-PD-1 immunotherapy using the global gene network association von Wu, Chia-Chin, Wang, Y. Alan, Livingston, J. Andrew, Zhang, Jianhua, Futreal, P. Andrew

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Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer von Kapoor, Avnish, Yao, Wantong, Ying, Haoqiang, Hua, Sujun, Liewen, Alison, Wang, Qiuyun, Zhong, Yi, Wu, Chang-Jiun, Sadanandam, Anguraj, Hu, Baoli, Chang, Qing, Chu, Gerald C., Al-Khalil, Ramsey, Jiang, Shan, Xia, Hongai, Fletcher-Sananikone, Eliot, Lim, Carol, Horwitz, Gillian I., Viale, Andrea, Pettazzoni, Piergiorgio, Sanchez, Nora, Wang, Huamin, Protopopov, Alexei, Zhang, Jianhua, Heffernan, Timothy, Johnson, Randy L., Chin, Lynda, Wang, Y. Alan, Draetta, Giulio, DePinho, Ronald A.

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Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma von Chen, Peiwen, Zhao, Di, Li, Jun, Liang, Xin, Li, Jiexi, Chang, Andrew, Henry, Verlene K., Lan, Zhengdao, Spring, Denise J., Rao, Ganesh, Wang, Y. Alan, DePinho, Ronald A.

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Effective combinatorial immunotherapy for penile squamous cell carcinoma von Huang, Tianhe, Cheng, Xi, Chahoud, Jad, Sarhan, Ahmed, Tamboli, Pheroze, Rao, Priya, Guo, Ming, Manyam, Ganiraju, Zhang, Li, Xiang, Yu, Han, Leng, Shang, Xiaoying, Deng, Pingna, Luo, Yanting, Lu, Xuemin, Feng, Shan, Ferrer, Magaly Martinez, Alan Wang, Y., DePinho, Ronald A., Pettaway, Curtis A., Lu, Xin

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Effective combinatorial immunotherapy for castration-resistant prostate cancer von Lu, Xin, Horner, James W., Paul, Erin, Shang, Xiaoying, Troncoso, Patricia, Deng, Pingna, Jiang, Shan, Chang, Qing, Spring, Denise J., Sharma, Padmanee, Zebala, John A., Maeda, Dean Y., Wang, Y. Alan, DePinho, Ronald A.

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USP21 deubiquitinase promotes pancreas cancer cell stemness via Wnt pathway activation von Hou, Pingping, Ma, Xingdi, Zhang, Qiang, Wu, Chang-Jiun, Liao, Wenting, Li, Jun, Wang, Huamin, Zhao, Jun, Zhou, Xin, Guan, Carolyn, Ackroyd, Jeffery, Jiang, Shan, Zhang, Jianhua, Spring, Denise J, Wang, Y Alan, DePinho, Ronald A

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USP14 promotes tryptophan metabolism and immune suppression by stabilizing IDO1 in colorectal cancer von Shi, Dongni, Wu, Xianqiu, Jian, Yunting, Wang, Junye, Huang, Chengmei, Mo, Shuang, Li, Yue, Li, Fengtian, Zhang, Chao, Zhang, Dongsheng, Zhang, Huizhong, Huang, Huilin, Chen, Xin, Wang, Y. Alan, Lin, Chuyong, Liu, Guozhen, Song, Libing, Liao, Wenting

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Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target von Wei, Jun, Marisetty, Anantha, Schrand, Brett, Gabrusiewicz, Konrad, Hashimoto, Yuuri, Ott, Martina, Grami, Zacharia, Kong, Ling-Yuan, Ling, Xiaoyang, Caruso, Hillary, Zhou, Shouhao, Wang, Y Alan, Fuller, Gregory N, Huse, Jason, Gilboa, Eli, Kang, Nannan, Huang, Xingxu, Verhaak, Roel, Li, Shulin, Heimberger, Amy B

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Stromal Modulation Reverses Primary Resistance to Immune Checkpoint Blockade in Pancreatic Cancer von Zhao, Jun, Xiao, Zhilan, Li, Tingting, Chen, Huiqin, Yuan, Ying, Wang, Y. Alan, Hsiao, Cheng-Hui, Chow, Diana S-L, Overwijk, Willem W, Li, Chun

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Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer von Dey, Prasenjit, Baddour, Joelle, Muller, Florian, Wu, Chia Chin, Wang, Huamin, Liao, Wen-Ting, Lan, Zangdao, Chen, Alina, Gutschner, Tony, Kang, Yaan, Fleming, Jason, Satani, Nikunj, Zhao, Di, Achreja, Abhinav, Yang, Lifeng, Lee, Jiyoon, Chang, Edward, Genovese, Giannicola, Viale, Andrea, Ying, Haoqiang, Draetta, Giulio, Maitra, Anirban, Wang, Y. Alan, Nagrath, Deepak, DePinho, Ronald A.

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Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth von Hu, Baoli, Wang, Qianghu, Wang, Y. Alan, Hua, Sujun, Sauvé, Charles-Etienne Gabriel, Ong, Derrick, Lan, Zheng D., Chang, Qing, Ho, Yan Wing, Monasterio, Marta Moreno, Lu, Xin, Zhong, Yi, Zhang, Jianhua, Deng, Pingna, Tan, Zhi, Wang, Guocan, Liao, Wen-Ting, Corley, Lynda J., Yan, Haiyan, Zhang, Junxia, You, Yongping, Liu, Ning, Cai, Linbo, Finocchiaro, Gaetano, Phillips, Joanna J., Berger, Mitchel S., Spring, Denise J., Hu, Jian, Sulman, Erik P., Fuller, Gregory N., Chin, Lynda, Verhaak, Roeland G.W., DePinho, Ronald A.

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Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression von Wang, Guocan, Lu, Xin, Dey, Prasenjit, Deng, Pingna, Wu, Chia Chin, Jiang, Shan, Fang, Zhuangna, Zhao, Kun, Konaparthi, Ramakrishna, Hua, Sujun, Zhang, Jianhua, Li-Ning-Tapia, Elsa M, Kapoor, Avnish, Wu, Chang-Jiun, Patel, Neelay Bhaskar, Guo, Zhenglin, Ramamoorthy, Vandhana, Tieu, Trang N, Heffernan, Tim, Zhao, Di, Shang, Xiaoying, Khadka, Sunada, Hou, Pingping, Hu, Baoli, Jin, Eun-Jung, Yao, Wantong, Pan, Xiaolu, Ding, Zhihu, Shi, Yanxia, Li, Liren, Chang, Qing, Troncoso, Patricia, Logothetis, Christopher J, McArthur, Mark J, Chin, Lynda, Wang, Y Alan, DePinho, Ronald A

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Oncogenic KRAS-Driven Metabolic Reprogramming in Pancreatic Cancer Cells Utilizes Cytokines from the Tumor Microenvironment von Dey, Prasenjit, Li, Jun, Zhang, Jianhua, Chaurasiya, Surendra, Strom, Anders, Wang, Huamin, Liao, Wen-Ting, Cavallaro, Frederick, Denz, Parker, Bernard, Vincent, Yen, Er-Yen, Genovese, Giannicola, Gulhati, Pat, Liu, Jielin, Chakravarti, Deepavali, Deng, Pingna, Zhang, Tingxin, Carbone, Federica, Chang, Qing, Ying, Haoqiang, Shang, Xiaoying, Spring, Denise J., Ghosh, Bidyut, Putluri, Nagireddy, Maitra, Anirban, Wang, Y. Alan, DePinho, Ronald A.

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Oncogenic Kras drives invasion and maintains metastases in colorectal cancer von Boutin, Adam T, Liao, Wen-Ting, Wang, Melody, Hwang, Soyoon Sarah, Karpinets, Tatiana V, Cheung, Hannah, Chu, Gerald C, Jiang, Shan, Hu, Jian, Chang, Kyle, Vilar, Eduardo, Song, Xingzhi, Zhang, Jianhua, Kopetz, Scott, Futreal, Andrew, Wang, Y Alan, Kwong, Lawrence N, DePinho, Ronald A

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Telomere dysfunction induces metabolic and mitochondrial compromise von Sahin, Ergün, Colla, Simona, Liesa, Marc, Moslehi, Javid, Müller, Florian L., Guo, Mira, Cooper, Marcus, Kotton, Darrell, Fabian, Attila J., Walkey, Carl, Maser, Richard S., Tonon, Giovanni, Foerster, Friedrich, Xiong, Robert, Wang, Y. Alan, Shukla, Sachet A., Jaskelioff, Mariela, Martin, Eric S., Heffernan, Timothy P., Protopopov, Alexei, Ivanova, Elena, Mahoney, John E., Kost-Alimova, Maria, Perry, Samuel R., Bronson, Roderick, Liao, Ronglih, Mulligan, Richard, Shirihai, Orian S., Chin, Lynda, DePinho, Ronald A.

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Passenger deletions generate therapeutic vulnerabilities in cancer von Muller, Florian L., Colla, Simona, Aquilanti, Elisa, Manzo, Veronica E., Genovese, Giannicola, Lee, Jaclyn, Eisenson, Daniel, Narurkar, Rujuta, Deng, Pingna, Nezi, Luigi, Lee, Michelle A., Hu, Baoli, Hu, Jian, Sahin, Ergun, Ong, Derrick, Fletcher-Sananikone, Eliot, Ho, Dennis, Kwong, Lawrence, Brennan, Cameron, Wang, Y. Alan, Chin, Lynda, DePinho, Ronald A.

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Telomerase Reactivation following Telomere Dysfunction Yields Murine Prostate Tumors with Bone Metastases von Ding, Zhihu, Wu, Chang-Jiun, Jaskelioff, Mariela, Ivanova, Elena, Kost-Alimova, Maria, Protopopov, Alexei, Chu, Gerald C., Wang, Guocan, Lu, Xin, Labrot, Emma S., Hu, Jian, Wang, Wei, Xiao, Yonghong, Zhang, Hailei, Zhang, Jianhua, Zhang, Jingfang, Gan, Boyi, Perry, Samuel R., Jiang, Shan, Li, Liren, Horner, James W., Wang, Y. Alan, Chin, Lynda, DePinho, Ronald A.

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Loss of FOXO1 Cooperates with TMPRSS2-ERG Overexpression to Promote Prostate Tumorigenesis and Cell Invasion von Yang, Yinhui, Blee, Alexandra M, Wang, Dejie, An, Jian, Pan, Yunqian, Yan, Yuqian, Ma, Tao, He, Yundong, Dugdale, Joseph, Hou, Xiaonan, Zhang, Jun, Weroha, S John, Zhu, Wei-Guo, Wang, Y Alan, DePinho, Ronald A, Xu, Wanhai, Huang, Haojie

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Telomere dysfunction activates YAP1 to drive tissue inflammation von Chakravarti, Deepavali, Hu, Baoli, Mao, Xizeng, Rashid, Asif, Li, Jiexi, Li, Jun, Liao, Wen-ting, Whitley, Elizabeth M., Dey, Prasenjit, Hou, Pingping, LaBella, Kyle A., Chang, Andrew, Wang, Guocan, Spring, Denise J., Deng, Pingna, Zhao, Di, Liang, Xin, Lan, Zhengdao, Lin, Yiyun, Sarkar, Sharmistha, Terranova, Christopher, Deribe, Yonathan Lissanu, Blutt, Sarah E., Okhuysen, Pablo, Zhang, Jianhua, Vilar, Eduardo, Nielsen, Ole Haagen, Dupont, Andrew, Younes, Mamoun, Patel, Kalyani R., Shroyer, Noah F., Rai, Kunal, Estes, Mary K., Wang, Y. Alan, Bertuch, Alison A., DePinho, Ronald A.

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p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation von DePinho, Ronald A, Zheng, Hongwu, Ying, Haoqiang, Yan, Haiyan, Kimmelman, Alec C, Hiller, David J, Chen, An-Jou, Perry, Samuel R, Tonon, Giovanni, Chu, Gerald C, Ding, Zhihu, Stommel, Jayne M, Dunn, Katherine L, Wiedemeyer, Ruprecht, You, Mingjian J, Brennan, Cameron, Wang, Y. Alan, Ligon, Keith L, Wong, Wing H, Chin, Lynda

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