Disruption of Runx1 and Runx3 Leads to Bone Marrow Failure and Leukemia Predisposition due to Transcriptional and DNA Repair Defects von Wang, Chelsia Qiuxia, Krishnan, Vaidehi, Tay, Lavina Sierra, Chin, Desmond Wai Loon, Koh, Cai Ping, Chooi, Jing Yuan, Nah, Giselle Sek Suan, Du, Linsen, Jacob, Bindya, Yamashita, Namiko, Lai, Soak Kuan, Tan, Tuan Zea, Mori, Seiichi, Tanuichi, Ichiro, Tergaonkar, Vinay, Ito, Yoshiaki, Osato, Motomi

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Gamma/delta T cells as cellular vehicles for anti-tumor immunity von Wang, Chelsia Qiuxia, Lim, Pei Yu, Tan, Andy Hee-Meng

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Hematopoietic stem cells acquire survival advantage by loss of RUNX1 methylation identified in familial leukemia von Matsumura, Takayoshi, Nakamura-Ishizu, Ayako, Muddineni, Siva Sai Naga Anurag, Tan, Darren Qiancheng, Wang, Chelsia Qiuxia, Tokunaga, Kenji, Tirado-Magallanes, Roberto, Sian, Stephanie, Benoukraf, Touati, Okuda, Tsukasa, Asou, Norio, Matsuoka, Masao, Osato, Motomi, Suda, Toshio

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Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy von Khattar, Ekta, Maung, Kyaw Ze Ya, Chew, Chen Li, Ghosh, Arkasubhra, Mok, Michelle Meng Huang, Lee, Pei, Zhang, Jun, Chor, Wei Hong Jeff, Cildir, Gökhan, Wang, Chelsia Qiuxia, Mohd-Ismail, Nur Khairiah, Chin, Desmond Wai Loon, Lee, Soo Chin, Yang, Henry, Shin, Yong-Jae, Nam, Do-Hyun, Chen, Liming, Kumar, Alan Prem, Deng, Lih Wen, Ikawa, Masahito, Gunaratne, Jayantha, Osato, Motomi, Tergaonkar, Vinay

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Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance von Numata, Akihiko, Kwok, Hui Si, Zhou, Qi-Ling, Li, Jia, Tirado-Magallanes, Roberto, Angarica, Vladimir Espinosa, Hannah, Rebecca, Park, Jihye, Wang, Chelsia Qiuxia, Krishnan, Vaidehi, Rajagopalan, Deepa, Zhang, Yanzhou, Zhou, Siqin, Welner, Robert S., Osato, Motomi, Jha, Sudhakar, Bohlander, Stefan K., Göttgens, Berthold, Yang, Henry, Benoukraf, Touati, Lough, John W., Bararia, Deepak, Tenen, Daniel G.

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Highly efficient Runx1 enhancer eR1-mediated genetic engineering for fetal, child and adult hematopoietic stem cells von Koh, Cai Ping, Bahirvani, Avinash Govind, Wang, Chelsia Qiuxia, Yokomizo, Tomomasa, Ng, Cherry Ee Lin, Du, Linsen, Tergaonkar, Vinay, Voon, Dominic Chih-Cheng, Kitamura, Hiroaki, Hosoi, Hiroki, Sonoki, Takashi, Michelle, Mok Meng Huang, Tan, Lii Jye, Niibori-Nambu, Akiko, Zhang, Yi, Perkins, Archibald S., Hossain, Zakir, Tenen, Daniel G., Ito, Yoshiaki, Venkatesh, Byrappa, Osato, Motomi

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Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis von Jacob, Bindya, Osato, Motomi, Yamashita, Namiko, Wang, Chelsia Qiuxia, Taniuchi, Ichiro, Littman, Dan R., Asou, Norio, Ito, Yoshiaki

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Runx3 deficiency results in myeloproliferative disorder in aged mice von Wang, Chelsia Qiuxia, Motoda, Lena, Satake, Masanobu, Ito, Yoshiaki, Taniuchi, Ichiro, Tergaonkar, Vinay, Osato, Motomi

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An Inhibitory Role for Human CD96 Endodomain in T Cell Anti-Tumor Responses von Wang, Chelsia Qiuxia, Choy, Fong Chan, Sanny, Arleen, Murakami, Takashi, Tan, Andy Hee-Meng, Lam, Kong-Peng

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Hematopoiesis specific loss of Cdk2 and Cdk4 results in increased erythrocyte size and delayed platelet recovery following stress von Jayapal, Senthil Raja, Wang, Chelsia Qiuxia, Bisteau, Xavier, Caldez, Matias J, Lim, Shuhui, Tergaonkar, Vinay, Osato, Motomi, Kaldis, Philipp

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379 Engineering of gamma/delta T cells derived from cord blood for chimeric antigen receptor-T cell therapies von Wang, Chelsia Qiuxia, Cheung, Alice, Tan, Andy Hee-Meng

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Integrin-α9 overexpression underlies the niche-independent maintenance of leukemia stem cells in acute myeloid leukemia von Niibori-Nambu, Akiko, Wang, Chelsia Qiuxia, Chin, Desmond Wai Loon, Chooi, Jing Yuan, Hosoi, Hiroki, Sonoki, Takashi, Tham, Cheng-Yong, Nah, Giselle Sek Suan, Cirovic, Branko, Tan, Darren Qiancheng, Takizawa, Hitoshi, Sashida, Goro, Goh, Yufen, Tng, Jiaqi, Fam, Wee Nih, Fullwood, Melissa Jane, Suda, Toshio, Yang, Henry, Tergaonkar, Vinay, Taniuchi, Ichiro, Li, Shang, Chng, Wee Joo, Osato, Motomi

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Activation of NOTCH signaling impedes cell proliferation and survival in acute megakaryoblastic leukemia von Ong, Kelly Ooi Kee, Mok, Michelle Meng Huang, Niibori-Nambu, Akiko, Du, Linsen, Yanagida, Masatoshi, Wang, Chelsia Qiuxia, Bahirvani, Avinash Govind, Chin, Desmond Wai Loon, Koh, Cai Ping, Ng, King Pan, Yamashita, Namiko, Jacob, Bindya, Yokomizo, Tomomasa, Takizawa, Hitoshi, Matsumura, Takayoshi, Suda, Toshio, Lau, Jie-ying Amelia, Tan, Tuan Zea, Mori, Seiichi, Yang, Henry, Iwasaki, Masayuki, Minami, Takashi, Asou, Norio, Sun, Qiao-Yang, Ding, Ling-Wen, Koeffler, H. Phillip, Tenen, Daniel G., Shimizu, Ritsuko, Yamamoto, Masayuki, Ito, Yoshiaki, Kham, Shirley Kow Yin, Yeoh, Allen Eng-Juh, Chng, Wee Joo, Osato, Motomi

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RUNX1-ETO (RUNX1-RUNX1T1) induces myeloid leukemia in mice in an age-dependent manner von Abdallah, Mohamed Gaber, Niibori-Nambu, Akiko, Morii, Mariko, Yokomizo, Takako, Yokomizo, Tomomasa, Ideue, Takako, Kubota, Sho, Teoh, Vania Swee Imm, Mok, Michelle Meng Huang, Wang, Chelsia Qiuxia, Omar, Abdellah Ali, Tokunaga, Kenji, Iwanaga, Eisaku, Matsuoka, Masao, Asou, Norio, Nakagata, Naomi, Araki, Kimi, AboElenin, Mabrouk, Madboly, Sayed Hamada, Sashida, Goro, Osato, Motomi

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Aberrant activation of the GIMAP enhancer by oncogenic transcription factors in T-cell acute lymphoblastic leukemia von Liau, W S, Tan, S H, Ngoc, P C T, Wang, C Q, Tergaonkar, V, Feng, H, Gong, Z, Osato, M, Look, A T, Sanda, T

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Cyclin A2 regulates erythrocyte morphology and numbers von Jayapal, Senthil Raja, Ang, Heather Yin-Kuan, Wang, Chelsia Qiuxia, Bisteau, Xavier, Caldez, Matias J, Xuan, Gan Xiao, Yu, Weimiao, Tergaonkar, Vinay, Osato, Motomi, Lim, Bing, Kaldis, Philipp

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Runx family genes, niche, and stem cell quiescence von Wang, Chelsia Qiuxia, Jacob, Bindya, Nah, Giselle Sek Suan, Osato, Motomi

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RUNX1 point mutations potentially identify a subset of early immature T-cell acute lymphoblastic leukaemia that may originate from differentiated T-cells von Mok, Michelle Meng Huang, Du, Linsen, Wang, Chelsia Qiuxia, Tergaonkar, Vinay, Liu, Te Chih, Yin Kham, Shirley Kow, Sanda, Takaomi, Yeoh, Allen Eng-Juh, Osato, Motomi

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Kinetin riboside preferentially induces apoptosis by modulating Bcl-2 family proteins and caspase-3 in cancer cells von Choi, Bo-Hwa, Kim, Wanil, Wang, Qiuxia Chelsia, Kim, Dong-Chan, Tan, Swee Ngin, Yong, Jean Wan Hong, Kim, Kyong-Tai, Yoon, Ho Sup

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Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance von Numata, Akihiko, Kwok, Hui Si, Zhou, Qi-Ling, Li, Jia, Tirado-Magallanes, Roberto, Angarica, Vladimir Espinosa, Hannah, Rebecca, Park, Jihye, Wang, Chelsia Qiuxia, Krishnan, Vaidehi, Rajagopalan, Deepa, Zhang, Yanzhou, Zhou, Siqin, Welner, Robert S, Osato, Motomi, Jha, Sudhakar, Bohlander, Stefan K, Göttgens, Berthold, Yang, Henry, Benoukraf, Touati, Lough, John W, Bararia, Deepak, Tenen, Daniel G

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