A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination von Wang, Anderson T., Kim, Taeho, Wagner, John E., Conti, Brooke A., Lach, Francis P., Huang, Athena L., Molina, Henrik, Sanborn, Erica M., Zierhut, Heather, Cornes, Belinda K., Abhyankar, Avinash, Sougnez, Carrie, Gabriel, Stacey B., Auerbach, Arleen D., Kowalczykowski, Stephen C., Smogorzewska, Agata

Volltext

Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links von Rickman, Kimberly A, Noonan, Raymond J, Lach, Francis P, Sridhar, Sunandini, Wang, Anderson T, Abhyankar, Avinash, Huang, Athena, Kelly, Michael, Auerbach, Arleen D, Smogorzewska, Agata

Volltext

SLFN11 informs on standard of care and novel treatments in a wide range of cancer models von Winkler, Claudia, Armenia, Joshua, Jones, Gemma N., Tobalina, Luis, Sale, Matthew J., Petreus, Tudor, Baird, Tarrion, Serra, Violeta, Wang, Anderson T., Lau, Alan, Garnett, Mathew J., Jaaks, Patricia, Coker, Elizabeth A., Pierce, Andrew J., O’Connor, Mark J., Leo, Elisabetta

Volltext

Human SNM1A and XPF-ERCC1 collaborate to initiate DNA interstrand cross-link repair von Wang, Anderson T, Sengerová, Blanka, Cattell, Emma, Inagawa, Takabumi, Hartley, Janet M, Kiakos, Konstantinos, Burgess-Brown, Nicola A, Swift, Lonnie P, Enzlin, Jacqueline H, Schofield, Christopher J, Gileadi, Opher, Hartley, John A, McHugh, Peter J

Volltext

SnapShot: Fanconi Anemia and Associated Proteins von Wang, Anderson T., Smogorzewska, Agata

Volltext

XPF-ERCC1 Participates in the Fanconi Anemia Pathway of Cross-Link Repair von Bhagwat, Nikhil, Olsen, Anna L., Wang, Anderson T., Hanada, Katsuhiro, Stuckert, Patricia, Kanaar, Roland, D'Andrea, Alan, Niedernhofer, Laura J., McHugh, Peter J.

Volltext

Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair von Sengerová, Blanka, Wang, Anderson T., McHugh, Peter J.

Volltext

Identification of a Molecularly-Defined Subset of Breast and Ovarian Cancer Models that Respond to WEE1 or ATR Inhibition, Overcoming PARP Inhibitor Resistance von Serra, Violeta, Wang, Anderson T, Castroviejo-Bermejo, Marta, Polanska, Urszula M, Palafox, Marta, Herencia-Ropero, Andrea, Jones, Gemma N, Lai, Zhongwu, Armenia, Joshua, Michopoulos, Filippos, Llop-Guevara, Alba, Brough, Rachel, Gulati, Aditi, Pettitt, Stephen J, Bulusu, Krishna C, Nikkilä, Jenni, Wilson, Zena, Hughes, Adina, Wijnhoven, Paul W G, Ahmed, Ambar, Bruna, Alejandra, Gris-Oliver, Albert, Guzman, Marta, Rodríguez, Olga, Grueso, Judit, Arribas, Joaquin, Cortés, Javier, Saura, Cristina, Lau, Alan, Critchlow, Susan, Dougherty, Brian, Caldas, Carlos, Mills, Gordon B, Barrett, J Carl, Forment, Josep V, Cadogan, Elaine, Lord, Christopher J, Cruz, Cristina, Balmaña, Judith, O'Connor, Mark J

Volltext

Fragment-Based Discovery of Novel MUS81 Inhibitors von Collie, Gavin W., Börjesson, Ulf, Chen, Yunhua, Dong, Zhiqiang, Di Fruscia, Paolo, Gohlke, Andrea, Hoyle, Anna, Hunt, Thomas A., Jesani, Mehul H., Luo, Haiou, Luptak, Jakub, Milbradt, Alexander G., Narasimhan, Priyanka, Packer, Martin, Patel, Saleha, Qiao, Jingchuan, Storer, R. Ian, Stubbs, Christopher J., Tart, Jonathan, Truman, Caroline, Wang, Anderson T., Wheeler, Matthew G., Winter-Holt, Jon

Volltext

Identification of human reductases that activate the dinitrobenzamide mustard prodrug PR-104A: A role for NADPH:cytochrome P450 oxidoreductase under hypoxia von Guise, Chris P., Wang, Anderson T., Theil, Anke, Bridewell, David J., Wilson, William R., Patterson, Adam V.

Volltext

Abstract 3721: A camptothecin-containing nanoparticle-drug conjugate combination with DDR agents provides a novel approach to increasing therapeutic index von Oplustil O’Connor, Lenka, Wang, Anderson T., Jones, David R., Odedra, Rajesh, Spreadborough, Michael, Wilson, Joanne, Smith, Aaron, Cotton, Peter, Reens, Jaimini, Barnes, Jen, Sheridan, Victoria, Eliasof, Scott, Tellez, Andres, Lau, Alan, Sadler, Claire, O’Connor, Mark J.

Volltext

Apollo: a healer of the genome? von Wang, Anderson T, McHugh, Peter J

Volltext

Identifying and overcoming a mechanism of resistance to WEE1 kinase inhibitor AZD1775 in high grade serous ovarian cancer cells

Volltext

Abstract B32: CRLX101, an investigational camptothecin-containing nanoparticle-drug conjugate, combined with DDR agents provides a novel approach to increasing therapeutic index von O'Connor, Lenka Oplustil, Wang, Anderson T., Jones, David, Odedra, Rajesh, Spreadborough, Michael, Wilson, Joanne, Smith, Aaron, Cotton, Peter, Reens, Jaimini, Barnes, Jen, Sheridan, Victoria, Tellez, Andres, Lau, Alan, Sadler, Claire, O'Connor, Mark J., Eliasof, Scott

Volltext

Apollo: A healer of the genome? von Wang, Anderson T., McHugh, Peter J.

Volltext

“Misinterpretation” of a histone mark is linked to aberrant stem cells and cancer development von Akihiko Yoshimura, Richard A. Franklin

Volltext

Identification of a Molecularly-Defined Subset of Breast and Ovarian Cancer Models that Respond to WEE1 or ATR Inhibition, Overcoming PARP Inhibitor Resistance von Serra, Violeta, Wang, Anderson T, Castroviejo-Bermejo, Marta, Polanska, Urszula, Palafox, Marta, Herencia Ropero, Andrea, Jones, Gemma, Lai, Zhongwu, Armenia, Joshua, Michopoulos, Filippos, Llop-Guevara, Alba, Brough, Rachel, Gulati, Aditi, Pettitt, Stephen, Bulusu, Krishna C, Nikkila, Jenni, Wilson, Zena, Hughes, Adina, Wijnhoven, Paul W.G, Ahmed, Ambar, Bruna, Alejandra, Gris-Oliver, Albert, Guzmán, Marta, Rodríguez, Olga, Grueso, Judit, Arribas, Joaquín V, Cortés, Javier, Saura Manich, Cristina, Lau, Alan, Critchlow, Susan, Dougherty, Brian, Caldas, Carlos, Mills, Gordon, Barrett, J. Carl, Forment, Josep V, Cadogan, Elaine, Lord, Christopher J, Cruz Zambrano, Cristina, Balmaña Gelpí, Judith, O'Connor, Mark J, Universitat Autònoma de Barcelona

Volltext bestellen

Stroke in China: advances and challenges in epidemiology, prevention, and management von Wu, Simiao, Wu, Bo, Liu, Ming, Chen, Zhengming, Wang, Wenzhi, Anderson, Craig S, Sandercock, Peter, Wang, Yongjun, Huang, Yining, Cui, Liying, Pu, Chuanqiang, Jia, Jianping, Zhang, Tong, Liu, Xinfeng, Zhang, Suming, Xie, Peng, Fan, Dongsheng, Ji, Xunming, Wong, Ka-Sing Lawrence, Wang, Longde, Wu, Simiao, Wu, Bo, Liu, Ming, Chen, Zhengming, Wang, Wenzhi, Anderson, Craig S, Sandercock, Peter, Wang, Yongjun, Huang, Yining, Cui, Liying, Pu, Chuanqiang, Jia, Jianping, Zhang, Tong, Liu, Xinfeng, Zhang, Suming, Xie, Peng, Fan, Dongsheng, Ji, Xunming, Wong, Ka-Sing Lawrence, Wang, Longde, Wei, Chenchen, Wang, Yanan, Cheng, Yajun, Liu, Yunhai, Li, Xin, Dong, Qiang, Zeng, Jinsheng, Peng, Bin, Xu, Yun, Yang, Yi, Wang, Yilong, Zhao, Gang, Wang, Wei, Xu, Yuming, Yang, Qingwu, He, Zhiyi, Wang, Shaoshi, You, Chao, Gao, Ying, Zhou, Dong, He, Li, Li, Zixiao, Yang, Jie, Lei, Chunyan, Zhao, Yuhua, Liu, Junfeng, Zhang, Shuting, Tao, Wendan, Hao, Zilong, Wang, Deren, Zhang, Shihong

Volltext

Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host von Ahn, Matae, Anderson, Danielle E., Zhang, Qian, Tan, Chee Wah, Lim, Beng Lee, Luko, Katarina, Wen, Ming, Chia, Wan Ni, Mani, Shailendra, Wang, Loo Chien, Ng, Justin Han Jia, Sobota, Radoslaw M., Dutertre, Charles-Antoine, Ginhoux, Florent, Shi, Zheng-Li, Irving, Aaron T., Wang, Lin-Fa

Volltext

Cabotegravir for HIV Prevention in Cisgender Men and Transgender Women von Landovitz, Raphael J., Donnell, Deborah, Clement, Meredith E., Hanscom, Brett, Cottle, Leslie, Coelho, Lara, Cabello, Robinson, Chariyalertsak, Suwat, Dunne, Eileen F., Frank, Ian, Gallardo-Cartagena, Jorge A., Gaur, Aditya H., Gonzales, Pedro, Tran, Ha V., Hinojosa, Juan C., Kallas, Esper G., Kelley, Colleen F., Losso, Marcelo H., Madruga, J. Valdez, Middelkoop, Keren, Phanuphak, Nittaya, Santos, Breno, Sued, Omar, Valencia Huamaní, Javier, Overton, Edgar T., Swaminathan, Shobha, del Rio, Carlos, Gulick, Roy M., Richardson, Paul, Sullivan, Philip, Piwowar-Manning, Estelle, Marzinke, Mark, Hendrix, Craig, Li, Maoji, Wang, Zhe, Marrazzo, Jeanne, Daar, Eric, Asmelash, Aida, Brown, Todd T., Anderson, Peter, Eshleman, Susan H., Bryan, Marcus, Blanchette, Cheryl, Lucas, Jonathan, Psaros, Christina, Safren, Steven, Sugarman, Jeremy, Scott, Hyman, Eron, Joseph J., Fields, Sheldon D., Sista, Nirupama D., Gomez-Feliciano, Kailazarid, Jennings, Andrea, Kofron, Ryan M., Holtz, Timothy H., Shin, Katherine, Rooney, James F., Smith, Kimberly Y., Spreen, William, Margolis, David, Rinehart, Alex, Adeyeye, Adeola, Cohen, Myron S., McCauley, Marybeth, Grinsztejn, Beatriz

Volltext