Comparative performance evaluation and systematic screening of solvents in a range of Grignard reactions von KADAM, Asha, NGUYEN, Mylinh, KOPACH, Michael, RICHARDSON, Paul, GALLOU, Fabrice, WANE, Zhao-Kui, WEI ZHANG

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Imidazotriazines: Spleen Tyrosine Kinase (Syk) Inhibitors Identified by Free-Energy Perturbation (FEP) von Lovering, Frank, Aevazelis, Cristina, Chang, Jeanne, Dehnhardt, Christoph, Fitz, Lori, Han, Seungil, Janz, Kristin, Lee, Julie, Kaila, Neelu, McDonald, Joseph, Moore, William, Moretto, Alessandro, Papaioannou, Nikolaos, Richard, David, Ryan, Mark S., Wan, Zhao-Kui, Thorarensen, Atli

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Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S)-2,2-Difluorocyclopropyl)((1 R,5 S)-3-(2-((1-methyl-1 H-pyrazol-4-yl)amino)pyrimidin-4-... von Fensome, Andrew, Ambler, Catherine M, Arnold, Eric, Banker, Mary Ellen, Brown, Matthew F, Chrencik, Jill, Clark, James D, Dowty, Martin E, Efremov, Ivan V, Flick, Andrew, Gerstenberger, Brian S, Gopalsamy, Ariamala, Hayward, Matthew M, Hegen, Martin, Hollingshead, Brett D, Jussif, Jason, Knafels, John D, Limburg, David C, Lin, David, Lin, Tsung H, Pierce, Betsy S, Saiah, Eddine, Sharma, Raman, Symanowicz, Peter T, Telliez, Jean-Baptiste, Trujillo, John I, Vajdos, Felix F, Vincent, Fabien, Wan, Zhao-Kui, Xing, Li, Yang, Xiaojing, Yang, Xin, Zhang, Liying

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Structure-Based Optimization of Protein Tyrosine Phosphatase 1B Inhibitors:  From the Active Site to the Second Phosphotyrosine Binding Site von Wilson, Douglas P, Wan, Zhao-Kui, Xu, Wei-Xin, Kirincich, Steven J, Follows, Bruce C, Joseph-McCarthy, Diane, Foreman, Kenneth, Moretto, Alessandro, Wu, Junjun, Zhu, Min, Binnun, Eva, Zhang, Yan-Ling, Tam, May, Erbe, David V, Tobin, James, Xu, Xin, Leung, Louis, Shilling, Adam, Tam, Steve Y, Mansour, Tarek S, Lee, Jinbo

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Assessing IRAK4 Functions in ABC DLBCL by IRAK4 Kinase Inhibition and Protein Degradation von Zhang, Jing, Fu, Liqiang, Shen, Bin, Liu, Yingtao, Wang, Wenqian, Cai, Xin, Kong, Linglong, Yan, Yilin, Meng, Ryan, Zhang, Zhuming, Chen, Ying-Nan P., Liu, Qian, Wan, Zhao-Kui, Zhou, Tianyuan, Wang, Xiaotao, Gavine, Paul, Del Rosario, Amanda, Ahn, Kay, Philippar, Ulrike, Attar, Ricardo, Yang, Jennifer, Xu, Yanping, Edwards, James P., Dai, Xuedong

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Asymmetric Ni(II)/Cr(II)-Mediated Coupling Reaction:  Catalytic Process von Choi, Hyeong-wook, Nakajima, Katsumasa, Demeke, Damtew, Kang, Fu-An, Jun, Hyuk-Sang, Wan, Zhao-Kui, Kishi, Yoshito

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Oxidative Palladium Catalysis in SNAr Reactions Leading to Heteroaryl Ethers from Pyridotriazol-1-yloxy Heterocycles with Aryl Boronic Acids von Wacharasindhu, Sumrit, Bardhan, Sujata, Wan, Zhao-Kui, Tabei, Keiko, Mansour, Tarek S

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Phosphonium-mediated cyclization of N-(2-aminophenyl)thioureas: efficient synthesis of 2-aminobenzimidazoles von Wan, Zhao-Kui, Ousman, Erena Farah, Papaioannou, Nikolaos, Saiah, Eddine

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Asymmetric Ni(II)/Cr(II)-Mediated Coupling Reaction:  Stoichiometric Process von Wan, Zhao-Kui, Choi, Hyeong-wook, Kang, Fu-An, Nakajima, Katsumasa, Demeke, Damtew, Kishi, Yoshito

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Design and optimization of a series of 4-(3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-2-amines: Dual inhibitors of TYK2 and JAK1 von Fensome, Andrew, Ambler, Catherine M., Arnold, Eric, Banker, Mary Ellen, Clark, James D., Dowty, Martin E., Efremov, Ivan V., Flick, Andrew, Gerstenberger, Brian S., Gifford, Roger S., Gopalsamy, Ariamala, Hegen, Martin, Jussif, Jason, Limburg, David C., Lin, Tsung H., Pierce, Betsy S., Sharma, Raman, Trujillo, John I., Vajdos, Felix F., Vincent, Fabien, Wan, Zhao-Kui, Xing, Li, Yang, Xiaojing, Yang, Xin

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Efficient Phosphonium-Mediated Synthesis of 2-Amino-1,3,4-oxadiazoles von Levins, Christopher G, Wan, Zhao-Kui

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The Scope and Mechanism of Phosphonium-Mediated SNAr Reactions in Heterocyclic Amides and Ureas von Wan, Zhao-Kui, Wacharasindhu, Sumrit, Levins, Christopher G, Lin, Melissa, Tabei, Keiko, Mansour, Tarek S

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Discovery of HSD-621 as a Potential Agent for the Treatment of Type 2 Diabetes von Wan, Zhao-Kui, Chenail, Eva, Li, Huan-Qiu, Ipek, Manus, Xiang, Jason, Suri, Vipin, Hahm, Seung, Bard, Joel, Svenson, Kristine, Xu, Xin, Tian, Xianbin, Wang, Mengmeng, Li, Xiangping, Johnson, Christian E, Qadri, Ariful, Panza, Darrell, Perreault, Mylene, Mansour, Tarek S, Tobin, James F, Saiah, Eddine

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An Efficient Direct Amination of Cyclic Amides and Cyclic Ureas von Wan, Zhao-Kui, Wacharasindhu, Sumrit, Binnun, Eva, Mansour, Tarek

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Aminopyrazole Carboxamide Bruton’s Tyrosine Kinase Inhibitors. Irreversible to Reversible Covalent Reactive Group Tuning von Schnute, Mark E, Benoit, Stephen E, Buchler, Ingrid P, Caspers, Nicole, Grapperhaus, Margaret L, Han, Seungil, Hotchandani, Rajeev, Huang, Nelson, Hughes, Robert O, Juba, Brian M, Kim, Kyung-Hee, Liu, Erica, McCarthy, Erin, Messing, Dean, Miyashiro, Joy S, Mohan, Shashi, O’Connell, Thomas N, Ohren, Jeffrey F, Parikh, Mihir D, Schmidt, Michelle, Selness, Shaun R, Springer, John R, Thanabal, Venkataraman, Trujillo, John I, Walker, Daniel P, Wan, Zhao-Kui, Withka, Jane M, Wittwer, Arthur J, Wood, Nancy L, Xing, Li, Zapf, Christoph W, Douhan, John

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Preparation of α-Haloacrylate Derivatives via Dimethyl Sulfoxide-Mediated Selective Dehydrohalogenation von Li, Wei, Li, Jianchang, Wan, Zhao-Kui, Wu, Junjun, Massefski, Walter

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N-Arylation of a hindered indoline as a route to 2-(2-methyl-1-(4-oxo-3,4-dihydrophthalazin-1-yl)-1H-indol-3-yl)acetic acid derivatives von Papaioannou, Nikolaos, Marathias, Vasilios, Wan, Zhao-Kui, Kaila, Neelu, Ali, Zahid, Saiah, Eddine

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Efficacious 11β-Hydroxysteroid Dehydrogenase Type I Inhibitors in the Diet-Induced Obesity Mouse Model von Wan, Zhao-Kui, Chenail, Eva, Xiang, Jason, Li, Huan-Qiu, Ipek, Manus, Bard, Joel, Svenson, Kristine, Mansour, Tarek S, Xu, Xin, Tian, Xianbin, Suri, Vipin, Hahm, Seung, Xing, Yuzhe, Johnson, Christian E, Li, Xiangping, Qadri, Ariful, Panza, Darrell, Perreault, Mylene, Tobin, James F, Saiah, Eddine

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Synthesis of Potent and Orally Efficacious 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor HSD-016 von Wan, Zhao-Kui, Chenail, Eva, Li, Huan-Qiu, Kendall, Christopher, Wang, Youchu, Gingras, Stéphane, Xiang, Jason, Massefski, Walter W, Mansour, Tarek, S, Saiah, Eddine

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Heteroaryl Ethers by Oxidative Palladium Catalysis of Pyridotriazol-1-yloxy Pyrimidines with Arylboronic Acids von Bardhan, Sujata, Wacharasindhu, Sumrit, Wan, Zhao-Kui, Mansour, Tarek S

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