CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines von Merk, Daniel J, Paul, Linda, Tsiami, Foteini, Hohenthanner, Helen, Kouchesfahani, Ghazal Mohseni, Haeusser, Lara A, Walter, Bianca, Brown, Adam, Persky, Nicole S, Root, David E, Tabatabai, Ghazaleh

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Alternative splicing of Apoptosis Stimulating Protein of TP53-2 (ASPP2) results in an oncogenic isoform promoting migration and therapy resistance in soft tissue sarcoma (STS) von Tsintari, Vasileia, Walter, Bianca, Fend, Falko, Overkamp, Mathis, Rothermundt, Christian, Lopez, Charles D., Schittenhelm, Marcus M., Kampa-Schittenhelm, Kerstin M.

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Functionally-instructed modifiers of response to ATR inhibition in experimental glioma von Walter, Bianca, Hirsch, Sophie, Kuhlburger, Laurence, Stahl, Aaron, Schnabel, Leonard, Wisser, Silas, Haeusser, Lara A, Tsiami, Foteini, Plöger, Sarah, Aghaallaei, Narges, Dick, Advaita M, Skokowa, Julia, Schmees, Christian, Templin, Markus, Schenke-Layland, Katja, Tatagiba, Marcos, Nahnsen, Sven, Merk, Daniel J, Tabatabai, Ghazaleh

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Multiparametric Longitudinal Profiling of RCAS-tva-Induced PDGFB-Driven Experimental Glioma von Becker, Hannes, Castaneda-Vega, Salvador, Patzwaldt, Kristin, Przystal, Justyna M., Walter, Bianca, Michelotti, Filippo C., Canjuga, Denis, Tatagiba, Marcos, Pichler, Bernd, Beck, Susanne C., Holland, Eric C., la Fougère, Christian, Tabatabai, Ghazaleh

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Alternative splicing of Apoptosis Stimulating Protein of TP53-2 von Tsintari, Vasileia, Walter, Bianca, Fend, Falko, Overkamp, Mathis, Rothermundt, Christian, Lopez, Charles D, Schittenhelm, Marcus M, Kampa-Schittenhelm, Kerstin M

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ATRT-32. GENOME-WIDE CRISPR AND SMALL-MOLECULE SCREENS UNCOVER TARGETABLE DEPENDENCIES IN AT/RTs von Merk, Daniel, Hirsch, Sophie, Walter, Bianca, Häusser, Lara, Persky, Nicole, Root, David, Schüller, Ulrich, Tabatabai, Ghazaleh

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EXTH-74. ATR INHIBITION IN EXPERIMENTAL GLIOMA von Walter, Bianca, Schnabel, Leonard, Hirsch, Sophie, Stahl, Aaron, Haeusser, Lara, Tsiami, Foteini, Kuhlburger, Laurence, Nahnsen, Sven, Templin, Markus, Schenke-Layland, Katja, Merk, Daniel, Tabatabai, Ghazaleh

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ATRT-19. Functional genomics reveal distinct modulators of response to CDK4/6 inhibitors in ATRTs von Merk, Daniel, Hirsch, Sohpie, Tsiami, Foteini, Walter, Bianca, Haeusser, Lara, Babaei, Sepideh, Admard, Jakob, Casadei, Nicolas, Roggia, Cristiana, Spohn, Michael, Schittenhelm, Jens, Singer, Stephan, Schüller, Ulrich, Piccioni, Federica, Persky, Nicole, Root, David, Claassen, Manfred, Tatagiba, Marcos, Tabatabai, Ghazaleh

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Dysregulation of the ASPP Protein Family (Apoptosis Stimulating Proteins of TP53) Is a Common Feature in High-Risk Acute Myeloid Leukemia (AML) von Kampa-Schittenhelm, Kerstin Maria, Kaiser, Max, Bajrami Saipi, Mihada, Walter, Bianca, Blumenstock, Gunnar, Kanz, Lothar, Schittenhelm, Marcus M

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EXTH-48. NOVEL COMBINATION THERAPY IN PRECLINICAL GLIOMA MODELS USING THE CELL CYCLE STABILIZING COMPOUND ARGYRIN F AND CHECKPOINT INHIBITION von Walter, Bianca, Canjuga, Denis, Yuez, Simge G, Ghosh, Michael, Bozko, Przemyslaw, Przystal, Justyna, Govindarajan, Parameswari, Anderle, Nicole, Keller, Anna-Lena, Tatagiba, Marcos, Schenke-Layland, Katja, Rammensee, Hans-Georg, Stevanovic, Stefan, Malek, Nisar P, Schmees, Christian, Tabatabai, Ghazaleh

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EXTH-69. FUNCTIONAL GENOMICS UNCOVER GENETIC DEPENDENCIES IN ATRTS von Merk, Daniel, Hirsch, Sophie, Tsiami, Foteini, Walter, Bianca, Haeusser, Lara, Babaei, Sepideh, Admard, Jakob, Casadei, Nicolas, Roggia, Cristiana, Spohn, Michael, Schittenhelm, Jens, Singer, Stephan, Schüller, Ulrich, Piccioni, Federica, Persky, Nicole, Root, David, Claassen, Manfred, Tatagiba, Marcos, Tabatabai, Ghazaleh

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Alternative splicing of the tumor suppressor ASPP2 results in a stress-inducible, oncogenic isoform prevalent in acute leukemia von Schittenhelm, Marcus Matthias, Walter, Bianca, Tsintari, Vasileia, Federmann, Birgit, Bajrami Saipi, Mihada, Akmut, Figen, Illing, Barbara, Mau-Holzmann, Ulrike, Fend, Falko, Lopez, Charles Darin, Kampa-Schittenhelm, Kerstin Maria

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Clinical outcome of biomarker-guided therapies in adult patients with tumors of the nervous system von Renovanz, Mirjam, Kurz, Sylvia C, Rieger, Johannes, Walter, Bianca, Becker, Hannes, Hille, Hanni, Bombach, Paula, Rieger, David, Grosse, Lucia, Häusser, Lara, Skardelly, Marco, Merk, Daniel J, Paulsen, Frank, Hoffmann, Elgin, Gani, Cihan, Neumann, Manuela, Beschorner, Rudi, Rieß, Olaf, Roggia, Cristiana, Schroeder, Christopher, Ossowski, Stephan, Armeanu-Ebinger, Sorin, Gschwind, Axel, Biskup, Saskia, Schulze, Martin, Fend, Falko, Singer, Stephan, Zender, Lars, Lengerke, Claudia, Brucker, Sara Yvonne, Engler, Tobias, Forschner, Andrea, Stenzl, Arnulf, Kohlbacher, Oliver, Nahnsen, Sven, Gabernet, Gisela, Fillinger, Sven, Bender, Benjamin, Ernemann, Ulrike, Öner, Öznur, Beha, Janina, Malek, Holly Sundberg, Möller, Yvonne, Ruhm, Kristina, Tatagiba, Marcos, Schittenhelm, Jens, Bitzer, Michael, Malek, Nisar, Zips, Daniel, Tabatabai, Ghazaleh

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Argyrin F Treatment‐Induced Vulnerabilities Lead to a Novel Combination Therapy in Experimental Glioma von Walter, Bianca, Canjuga, Denis, Yüz, Simge G., Ghosh, Michael, Bozko, Przemyslaw, Przystal, Justyna M., Govindarajan, Parameswari, Anderle, Nicole, Keller, Anna‐Lena, Tatagiba, Marcos, Schenke‐Layland, Katja, Rammensee, Hans‐Georg, Stevanovic, Stefan, Malek, Nisar P., Schmees, Christian, Tabatabai, Ghazaleh

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Alternative splicing of the tumor suppressor ASPP2 results in a stress-inducible, oncogenic isoform prevalent in acute leukemiaResearch in context von Marcus Matthias Schittenhelm, Bianca Walter, Vasileia Tsintari, Birgit Federmann, Mihada Bajrami Saipi, Figen Akmut, Barbara Illing, Ulrike Mau-Holzmann, Falko Fend, Charles Darin Lopez, Kerstin Maria Kampa-Schittenhelm

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Experimental glioma with high bHLH expression harbor increased replicative stress and are sensitive toward ATR inhibition von Koch, Marilin Sophia, Czemmel, Stefan, Lennartz, Felix, Beyeler, Sarah, Rajaraman, Srinath, Przystal, Justyna Magdalena, Govindarajan, Parameswari, Canjuga, Denis, Neumann, Manfred, Rizzu, Patrizia, Zwirner, Stefan, Hoetker, Michael Stefan, Zender, Lars, Walter, Bianca, Tatagiba, Marcos, Raineteau, Olivier, Heutink, Peter, Nahnsen, Sven, Tabatabai, Ghazaleh

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Additional file 5 of CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines von Merk, Daniel J., Paul, Linda, Tsiami, Foteini, Hohenthanner, Helen, Kouchesfahani, Ghazal Mohseni, Haeusser, Lara A., Walter, Bianca, Brown, Adam, Persky, Nicole S., Root, David E., Tabatabai, Ghazaleh

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Additional file 4 of CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines von Merk, Daniel J., Paul, Linda, Tsiami, Foteini, Hohenthanner, Helen, Kouchesfahani, Ghazal Mohseni, Haeusser, Lara A., Walter, Bianca, Brown, Adam, Persky, Nicole S., Root, David E., Tabatabai, Ghazaleh

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Additional file 3 of CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines von Merk, Daniel J., Paul, Linda, Tsiami, Foteini, Hohenthanner, Helen, Kouchesfahani, Ghazal Mohseni, Haeusser, Lara A., Walter, Bianca, Brown, Adam, Persky, Nicole S., Root, David E., Tabatabai, Ghazaleh

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Additional file 1 of CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines von Merk, Daniel J., Paul, Linda, Tsiami, Foteini, Hohenthanner, Helen, Kouchesfahani, Ghazal Mohseni, Haeusser, Lara A., Walter, Bianca, Brown, Adam, Persky, Nicole S., Root, David E., Tabatabai, Ghazaleh

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