Structural characterization of the Streptococcus pneumoniae carbohydrate substrate‐binding protein SP0092 von Culurgioni, Simone, Tang, Minzhe, Walsh, Martin Austin

Volltext

AI-Driven Discovery of SARS-CoV‑2 Main Protease Fragment-like Inhibitors with Antiviral Activity In Vitro von Saramago, Luiz Carlos, Santana, Marcos V., Gomes, Bárbara Figueira, Dantas, Rafael Ferreira, Senger, Mario R., Oliveira Borges, Pedro Henrique, Ferreira, Vivian Neuza dos Santos, dos Santos Rosa, Alice, Tucci, Amanda Resende, Dias Miranda, Milene, Lukacik, Petra, Strain-Damerell, Claire, Owen, C. David, Walsh, Martin Austin, Ferreira, Sabrina Baptista, Silva-Junior, Floriano Paes

Volltext

SynchLink: an iOS app for ISPyB von Ginn, Helen Mary, Mostefaoui, Ghita Kouadri, Levik, Karl Erik, Grimes, Jonathan Mark, Walsh, Martin Austin, Ashton, Alun William, Stuart, David Ian

Volltext

High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells von Griner, Lesley A. Mathews, Guha, Rajarshi, Shinn, Paul, Young, Ryan M., Keller, Jonathan M., Liu, Dongbo, Goldlust, Ian S., Yasgar, Adam, McKnight, Crystal, Boxer, Matthew B., Duveau, Damien Y., Jiang, Jian-Kang, Michael, Sam, Mierzwa, Tim, Huang, Wenwei, Walsh, Martin J., Mott, Bryan T., Patel, Paresma, Leister, William, Maloney, David J., Leclair, Christopher A., Rai, Ganesha, Jadhav, Ajit, Peyser, Brian D., Austin, Christopher P., Martin, Scott E., Simeonov, Anton, Ferrer, Marc, Staudt, Louis M., Thomas, Craig J.

Volltext

Comparison of bivalent and monovalent SARS-CoV-2 variant vaccines: the phase 2 randomized open-label COVAIL trial von Branche, Angela R., Rouphael, Nadine G., Diemert, David J., Falsey, Ann R., Losada, Cecilia, Baden, Lindsey R., Frey, Sharon E., Whitaker, Jennifer A., Little, Susan J., Anderson, Evan J., Walter, Emmanuel B., Novak, Richard M., Rupp, Richard, Jackson, Lisa A., Babu, Tara M., Kottkamp, Angelica C., Luetkemeyer, Anne F., Immergluck, Lilly C., Presti, Rachel M., Bäcker, Martín, Winokur, Patricia L., Mahgoub, Siham M., Goepfert, Paul A., Fusco, Dahlene N., Malkin, Elissa, Bethony, Jeffrey M., Walsh, Edward E., Graciaa, Daniel S., Samaha, Hady, Sherman, Amy C., Walsh, Stephen R., Abate, Getahun, Oikonomopoulou, Zacharoula, El Sahly, Hana M., Martin, Thomas C. S., Kamidani, Satoshi, Smith, Michael J., Ladner, Benjamin G., Porterfield, Laura, Dunstan, Maya, Wald, Anna, Davis, Tamia, Atmar, Robert L., Mulligan, Mark J., Lyke, Kirsten E., Posavad, Christine M., Meagher, Megan A., Stephens, David S., Neuzil, Kathleen M., Abebe, Kuleni, Hill, Heather, Albert, Jim, Telu, Kalyani, Mu, Jinjian, Lewis, Teri C., Giebeig, Lisa A., Eaton, Amanda, Netzl, Antonia, Wilks, Samuel H., Türeli, Sina, Makhene, Mamodikoe, Crandon, Sonja, Montefiori, David C., Makowski, Mat, Smith, Derek J., Nayak, Seema U., Roberts, Paul C., Beigel, John H.

Volltext

Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer von Lin, WeiYu, Xu, Daqi, Austin, Cary D, Caplazi, Patrick, Senger, Kate, Sun, Yonglian, Jeet, Surinder, Young, Judy, Delarosa, Donnie, Suto, Eric, Huang, Zhiyu, Zhang, Juan, Yan, Donghong, Corzo, Cesar, Barck, Kai, Rajan, Sharmila, Looney, Carrie, Gandham, Vineela, Lesch, Justin, Liang, Wei-Ching, Mai, Elaine, Ngu, Hai, Ratti, Navneet, Chen, Yongmei, Misner, Dinah, Lin, Tori, Danilenko, Dimitry, Katavolos, Paula, Doudemont, Estelle, Uppal, Hirdesh, Eastham, Jeffrey, Mak, Judy, de Almeida, Patricia E, Bao, Katherine, Hadadianpour, Azadeh, Keir, Mary, Carano, Richard A D, Diehl, Lauri, Xu, Min, Wu, Yan, Weimer, Robby M, DeVoss, Jason, Lee, Wyne P, Balazs, Mercedesz, Walsh, Kevin, Alatsis, Kathila R, Martin, Flavius, Zarrin, Ali A

Volltext

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids von Reimer, Katharina C., Nagai, James S., Varghese, Finny S., Overheul, Gijs J., Roverts, Rona, Willemsen, Brigith, Beukenboom, Marcel, Dunnen, Wilfred den, Triana, Sergio H., Timm, Marie-Cherelle, van den Berge, Bartholomeus T., Nlandu, Quincy, Heijnert, Joelle, Bindels, Eric M.J., Hoogenboezem, Remco M., Mooren, Fieke, Kuppe, Christoph, Grünberg, Katrien, Steenbergen, Eric J., Czogalla, Jan, Sommerdijk, Nico, Akiva, Anat, Boor, Peter, Huber, Tobias B., Bar-David, Elad, Barr, Haim, Boby, Melissa L., Borden, Bruce, Bowman, Gregory R., Brun, Juliane, BVNBS, Sarma, Carbery, Anna, Chernychenko, Eugene, Clyde, Austin, Coffland, Joseph E., Cole, Jason, Cox, Lisa, Dudgeon, Tim, Dunnett, Louise, Erez, Noam, Fate, Gwen, Ferrins, Lori, Foster, Richard, Foster, Holly, Gabizon, Ronen, Gawriljuk, Victor O., Gehrtz, Paul, Gileadi, Carina, Giroud, Charline, Glen, Robert, Gorichko, Marian, Griffen, Ed J., Heer, Jag, Hill, Michelle, Horrell, Sam, Jajack, Andrew, De Jonghe, Steven, Kantsadi, Anastassia L., Koekemoer, Lizbe, Lee, Alpha A., Lefker, Bruce A., Macdonald, Hannah Bruce, Maclean, Beth, McCorkindale, Willam, McGovern, Briana L., Michurin, Oleg, Morris, Aaron, Morris, Garret M., Neyts, Johan, Oliva, Glaucius, Overheul, Gijs J., Owen, David, Psenak, Vladimir, Pai, Ruby, Paran, Nir, Perry, Benjamin, Pingle, Maneesh, Politi, Boaz, Powell, Ailsa, Puni, Reut, Resnick, Efrat, Rosales, Romel, Schofield, Chris, Shafeev, Mikhail, Sittner, Assa, Skyner, Rachael, Spencer, John, Tamir, Hadas, Tennant, Rachael, Tumber, Anthony, van Rij, Ronald P., Voelz, Vincent, Volkamer, Andra, von Delft, Annette, White, Kris M., Wright, Nathan, Zidane, Hadeer, Costa, Ivan G., Schneider, Rebekka K., Smeets, Bart

Volltext

Effect of Convalescent Plasma on Organ Support–Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial von Estcourt, Lise J, Turgeon, Alexis F, McQuilten, Zoe K, McVerry, Bryan J, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M, Arnold, Donald M, Beane, Abigail, Bégin, Philippe, van Bentum-Puijk, Wilma, Berry, Lindsay R, Bhimani, Zahra, Birchall, Janet E, Bonten, Marc J. M, Bradbury, Charlotte A, Brunkhorst, Frank M, Buxton, Meredith, Callum, Jeannie L, Chassé, Michaël, Cheng, Allen C, Cove, Matthew E, Daly, James, Derde, Lennie, Detry, Michelle A, De Jong, Menno, Evans, Amy, Fergusson, Dean A, Fish, Matthew, Fitzgerald, Mark, Foley, Claire, Goossens, Herman, Gordon, Anthony C, Gosbell, Iain B, Green, Cameron, Haniffa, Rashan, Harvala, Heli, Higgins, Alisa M, Hills, Thomas E, Hoad, Veronica C, Horvat, Christopher, Huang, David T, Hudson, Cara L, Ichihara, Nao, Laing, Emma, Lamikanra, Abigail A, Lamontagne, François, Lawler, Patrick R, Linstrum, Kelsey, Litton, Edward, Lorenzi, Elizabeth, MacLennan, Sheila, Marshall, John, McAuley, Daniel F, McDyer, John F, McGlothlin, Anna, McGuinness, Shay, Miflin, Gail, Montgomery, Stephanie, Mouncey, Paul R, Murthy, Srinivas, Nichol, Alistair, Parke, Rachael, Parker, Jane C, Priddee, Nicole, Purcell, Damian F. J, Reyes, Luis F, Richardson, Peter, Robitaille, Nancy, Rowan, Kathryn M, Rynne, Jennifer, Saito, Hiroki, Santos, Marlene, Saunders, Christina T, Serpa Neto, Ary, Seymour, Christopher W, Silversides, Jon A, Tinmouth, Alan A, Triulzi, Darrell J, Turner, Anne M, van de Veerdonk, Frank, Walsh, Timothy S, Wood, Erica M, Berry, Scott, Lewis, Roger J, Menon, David K, McArthur, Colin, Zarychanski, Ryan, Angus, Derek C, Webb, Steve A, Roberts, David J, Shankar-Hari, Manu

Volltext

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis von Anastasiou, Dimitrios, Yu, Yimin, Israelsen, William J, Jiang, Jian-Kang, Boxer, Matthew B, Hong, Bum Soo, Tempel, Wolfram, Dimov, Svetoslav, Shen, Min, Jha, Abhishek, Yang, Hua, Mattaini, Katherine R, Metallo, Christian M, Fiske, Brian P, Courtney, Kevin D, Malstrom, Scott, Khan, Tahsin M, Kung, Charles, Skoumbourdis, Amanda P, Veith, Henrike, Southall, Noel, Walsh, Martin J, Brimacombe, Kyle R, Leister, William, Lunt, Sophia Y, Johnson, Zachary R, Yen, Katharine E, Kunii, Kaiko, Davidson, Shawn M, Christofk, Heather R, Austin, Christopher P, Inglese, James, Harris, Marian H, Asara, John M, Stephanopoulos, Gregory, Salituro, Francesco G, Jin, Shengfang, Dang, Lenny, Auld, Douglas S, Park, Hee-Won, Cantley, Lewis C, Thomas, Craig J, Vander Heiden, Matthew G

Volltext

Exome copy number variant detection, analysis, and classification in a large cohort of families with undiagnosed rare genetic disease von Lemire, Gabrielle, Sanchis-Juan, Alba, Russell, Kathryn, Baxter, Samantha, Chao, Katherine R., Singer-Berk, Moriel, Groopman, Emily, Wong, Isaac, England, Eleina, Goodrich, Julia, Pais, Lynn, Austin-Tse, Christina, DiTroia, Stephanie, O’Heir, Emily, Ganesh, Vijay S., Wojcik, Monica H., Evangelista, Emily, Snow, Hana, Osei-Owusu, Ikeoluwa, Fu, Jack, Singh, Mugdha, Mostovoy, Yulia, Huang, Steve, Garimella, Kiran, Kirkham, Samantha L., Neil, Jennifer E., Shao, Diane D., Walsh, Christopher A., Argilli, Emanuela, Le, Carolyn, Sherr, Elliott H., Gleeson, Joseph G., Shril, Shirlee, Schneider, Ronen, Hildebrandt, Friedhelm, Sankaran, Vijay G., Madden, Jill A., Genetti, Casie A., Beggs, Alan H., Agrawal, Pankaj B., Bujakowska, Kinga M., Place, Emily, Pierce, Eric A., Donkervoort, Sandra, Bönnemann, Carsten G., Gallacher, Lyndon, Stark, Zornitza, Tan, Tiong Yang, White, Susan M., Töpf, Ana, Straub, Volker, Fleming, Mark D., Pollak, Martin R., Õunap, Katrin, Pajusalu, Sander, Donald, Kirsten A., Bruwer, Zandre, Ravenscroft, Gianina, Laing, Nigel G., MacArthur, Daniel G., Rehm, Heidi L., Talkowski, Michael E., Brand, Harrison, O’Donnell-Luria, Anne

Volltext

Duration of noninvasive respiratory support and risk for bronchopulmonary dysplasia or death von Gentle, Samuel J., Carper, Benjamin, Laughon, Matthew M., Jensen, Erik A., Williams, Austin, Travers, Colm P., Ambalavanan, Namasivayam, Lal, Charitharth V., Carlo, Waldemar A.

Volltext

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis von Anastasiou, Dimitrios, Yu, Yimin, Israelsen, William J, Jiang, Jian-Kang, Boxer, Matthew B, Hong, Bum Soo, Tempel, Wolfram, Dimov, Svetoslav, Shen, Min, Jha, Abhishek, Yang, Hua, Mattaini, Katherine R, Metallo, Christian M, Fiske, Brian P, Courtney, Kevin D, Malstrom, Scott, Khan, Tahsin M, Kung, Charles, Skoumbourdis, Amanda P, Veith, Henrike, Southall, Noel, Walsh, Martin J, Brimacombe, Kyle R, Leister, William, Lunt, Sophia Y, Johnson, Zachary R, Yen, Katharine E, Kunii, Kaiko, Davidson, Shawn M, Christofk, Heather R, Austin, Christopher P, Inglese, James, Harris, Marian H, Asara, John M, Stephanopoulos, Gregory, Salituro, Francesco G, Jin, Shengfang, Dang, Lenny, Auld, Douglas S, Park, Hee-Won, Cantley, Lewis C, Thomas, Craig J, Vander Heiden, Matthew G

Volltext

Outcomes following small bowel obstruction due to malignancy in the national audit of small bowel obstruction von Acheson, Austin, Hamady, Zaed, Marriott, Paul J., Maynard, Nick, Singh, Pritam, Tierney, Gillian, Verjee, Azmina, Wild, Jonathan RL, Abdulaal, Y., Anderson, D., Boulton, R., Borg, C., Bouras, G., Brown, L., Cook, T., Dowson, H., Farag, S., Faulkner, G., Harikrishnan, A., Kallam, R., Lazim, T., Mathur, P., Maude, K., McArthur, D., Messenger, D., Singh, B., Peristerakis, I., Qureshi, A., Shah, P., Smith, I., Ventham, N., Akram, F., Aldred, E., Ali, A., Asour, A., Azhar, B., Berger, C., Bhasin, S., Broadhurst, J., Butcher, K., Conn, G., Cooper, S., Crook, R., da Silva, L., Dindyal, S., El-Sharif, M., Elsaid, N., Fisher, O., Francis, N., Fung, D., Groundwater, E., Hanna, T., Healy, R., Heller, S., Hicks, G., Ng, P., Hossaini, S., Hubbard, T., Iqbal, M., Jokhan, S., Kane, E., Khan, T., Lau, A., Lim, J., Lloyd, P., Mistry, P., Mohamed, E., Moore, N., Murgitroyd, E., Mykoniatis, I., O'Hara, R., Olivier, J., Payne, C., Phelan, L., Rangarajan, K., Rehman, A., Rehan, S., Saghir, T., Shields, T., Smith, F., Tongo, F., Turnbull, A., Whyler, M., Williamson, A., Wong, J., Athersmith, M., Blake, L., Deputy, M., Gunasekaran, S., Heard, R., Kshatriya, K., Kumar, S., Ng, C., Oke, O., Pouzi, M., Richards, E., Swinkin, M., Takacs, K., Valero, C., Venza, M.

Volltext

Preconditioning Shields Against Vascular Events in Surgery (SAVES), a multicentre feasibility trial of preconditioning against adverse events in major vascular surgery: study proto... von Healy, Donagh, Clarke-Moloney, Mary, Gaughan, Brendan, O'Daly, Siobhan, Hausenloy, Derek, Sharif, Faisal, Newell, John, O'Donnell, Martin, Grace, Pierce, Forbes, John F, Cullen, Walter, Kavanagh, Eamon, Burke, Paul, Cross, Simon, Dowdall, Joseph, McMonagle, Morgan, Fulton, Greg, Manning, Brian J, Kheirelseid, Elrasheid A H, Leahy, Austin, Moneley, Daragh, Naughton, Peter, Boyle, Emily, McHugh, Seamus, Madhaven, Prakash, O'Neill, Sean, Martin, Zenia, Courtney, Donal, Tubassam, Muhammed, Sultan, Sherif, McCartan, Damian, Medani, Mekki, Walsh, Stewart

Volltext

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis von Anastasiou, Dimitrios, Yu, Yimin, Israelsen, William J, Jiang, Jian-kang, Boxer, Matthew B, Hong, Bum Soo, Tempel, Wolfram, Dimov, Svetoslav, Shen, Min, Jha, Abhishek, Yang, Hua, Mattaini, Katherine R, Metallo, Christian M, Fiske, Brian P, Courtney, Kevin D, Malstrom, Scott, Khan, Tahsin M, Kung, Charles, Skoumbourdis, Amanda P, Veith, Henrike, Southall, Noel, Walsh, Martin J, Brimacombe, Kyle R, Leister, William, Lunt, Sophia Y, Johnson, Zachary R, Yen, Katharine E, Kunii, Kaiko, Davidson, Shawn M, Christofk, Heather R, Austin, Christopher P, Inglese, James, Harris, Marian H, Asara, John M, Stephanopoulos, Gregory, Salituro, Francesco G, Jin, Shengfang, Dang, Lenny, Auld, Douglas S, Park, Hee-won, Cantley, Lewis C, Thomas, Craig J, Vander Heiden, Matthew G

Volltext

Preconditioning shields against vascular events in surgery (saves), a multicentre feasibility trial of preconditioning against adverse events in major vascular surgery: study proto... von Healy, Donagh, Clarke-Moloney, Mary, Gaughan, Brendan, O’Daly, Siobhan, Hausenloy, Derek, Sharif, Faisal, Newell, John, O’Donnell, Martin, Grace, Pierce, Forbes, John F, Cullen, Walter, Kavanagh, Eamon, Burke, Paul, Cross, Simon, Dowdall, Joseph, McMonagle, Morgan, Fulton, Greg, Manning, Brian J, Kheirelseid, Elrasheid AH, Leahy, Austin, Moneley, Daragh, Naughton, Peter, Boyle, Emily, McHugh, Seamus, Madhaven, Prakash, O’Neill, Sean, Martin, Zenia, Courtney, Donal, Tubassam, Muhammed, Sultan, Sherif, McCartan, Damian, Medani, Mekki, Walsh, Stewart

Volltext

Erratum: Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis von Anastasiou, Dimitrios, Yu, Yimin, Israelsen, William J, Jiang, Jian-kang, Boxer, Matthew B, Hong, Bum Soo, Tempel, Wolfram, Dimov, Svetoslav, Shen, Min, Jha, Abhishek, Yang, Hua, Mattaini, Katherine R, Metallo, Christian M, Fiske, Brian P, Courtney, Kevin D, Malstrom, Scott, Khan, Tahsin M, Kung, Charles, Skoumbourdis, Amanda P, Veith, Henrike, Southall, Noel, Walsh, Martin J, Brimacombe, Kyle R, Leister, William, Lunt, Sophia Y, Johnson, Zachary R, Yen, Katharine E, Kunii, Kaiko, Davidson, Shawn M, Christofk, Heather R, Austin, Christopher P, Inglese, James, Harris, Marian H, Asara, John M, Stephanopoulos, Gregory, Salituro, Francesco G, Jin, Shengfang, Dang, Lenny, Auld, Douglas S, Park, Hee-Won, Cantley, Lewis C, Thomas, Craig J, Vander Heiden, Matthew G

Volltext

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis von Anastasiou, Dimitrios, Yu, Yimin, Israelsen, William J, Jiang, Jian-kang, Boxer, Matthew B, Hong, Bum Soo, Tempel, Wolfram, Dimov, Svetoslav, Shen, Min, Jha, Abhishek, Yang, Hua, Mattaini, Katherine R, Metallo, Christian M, Fiske, Brian P, Courtney, Kevin D, Malstrom, Scott, Khan, Tahsin M, Kung, Charles, Skoumbourdis, Amanda P, Veith, Henrike, Southall, Noel, Walsh, Martin J, Brimacombe, Kyle R, Leister, William, Lunt, Sophia Y, Johnson, Zachary R, Yen, Katharine E, Kunii, Kaiko, Davidson, Shawn M, Christofk, Heather R, Austin, Christopher P, Inglese, James, Harris, Marian H, Asara, John M, Stephanopoulos, Gregory, Salituro, Francesco G, Jin, Shengfang, Dang, Lenny, Auld, Douglas S, Park, Hee-Won, Cantley, Lewis C, Thomas, Craig J, Vander Heiden, Matthew G

Volltext