Combination of Antibody That Inhibits Ligand-Independent HER3 Dimerization and a p110α Inhibitor Potently Blocks PI3K Signaling and Growth of HER2+ Breast Cancers von GARRETT, Joan T, SUTTON, Cammie R, KURUPI, Richard, BIALUCHA, Carl Uli, ETTENBERG, Seth A, COLLINS, Scott D, QING SHENG, WALLWEBER, Jerry, DEFAZIO-ELI, Lisa, ARTEAGA, Carlos L

Volltext

Abstract 1558: Association of ErbB/HER biomarkers with antitumor activity of the anti-ErbB3/HER3 monoclonal antibody KTN3379 in SCCHN von Alvarado, Diego, Wallweber, Jerry, Seibel, Scott, Chenna, Ahmed, Ravanera, Roy, Huang, Weidong, Stathas, David, Theobald, Paul, LaVallee, Theresa M.

Volltext

Abstract 1196: Combination of neuregulin with EGFR activation signatures predict activity of the anti-ErbB3 antibody KTN3379 in SCCHN von Ligon, Gwenda F., Lillquist, Jay S., Seibel, Scott B., Wallweber, Jerry, Neumeister, Veronique, Rimm, David L., LaVallee, Theresa M., Alvarado, Diego

Volltext

Abstract 5461: A HER3 antibody that blocks ligand-independent HER2-HER3 dimerization sensitizes to HER2 and PI3K inhibitors von Garrett, Joan T., Sutton, Cammie R., Bialucha, Carl Uli, Ettenberg, Seth A., Wallweber, Jerry, DeFazio-Eli, Lisa, Arteaga, Carlos L.

Volltext

Abstract 3029: Profiling HER3/ErbB3 activation in formalin-fixed, paraffin-embedded (FFPE) breast tumor samples that express high and low HER2/ErbB2 levels using proximity-based im... von Wallweber, Jerry, Chenna, Ahmed, Ravanera, Roy, Huang, Weidong, Stathas, David, Marshall, Gayle, Womack, Chris, Pritchard, Alison, Thress, Ken, Barrett, Carl, Petropoulos, Christos, DeFazio Eli, Lisa, Winslow, John

Volltext

Abstract LB-323: Subclassification of squamous cell carcinomas of the head and neck based on HER/ErbB and c-MET receptor protein expression and activation profiles von Wallweber, Jerry, Badal, Youssouf, Twomey, Brian, Dang, Tam, Bose, Jolly, Dao-Pick, Trang, Zhang, Jianhuan, Stathas, Dave, Dua, Rajiv, Sherwood, Tom, Huang, Weidong, Parry, Gordon, Oliner, Kelly, Winslow, John W.

Volltext

Abstract LB-66: Quantitative assessment of HER/erbB receptor protein expression and activation status in FFPE tumor samples identifies an activated HER1 signature in squamous cell... von Wallweber, Jerry W., Dang, Tam, Twomey, Brian, Dao-Pick, Trang, Bose, Jolly, Zhang, Jianhuan, Nguyen, Xuan-Thao, Stathas, Dave, Mukherjee, Ali, Dua, Rajiv, Sherwood, Tom, Huang, Weidong, Parry, Gordon, Oliner, Kelly, Winslow, John

Volltext