Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors von Walker, Nigel P. C, Perlmann, Thomas, Wang, Zhulun, Benoit, Gérard, Liu, Jinsong, Prasad, Srividya, Aarnisalo, Piia, Liu, Xiaohong, Xu, Haoda

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The Crystal Structure of PCSK9: A Regulator of Plasma LDL-Cholesterol von Piper, Derek E., Jackson, Simon, Liu, Qiang, Romanow, William G., Shetterly, Susan, Thibault, Stephen T., Shan, Bei, Walker, Nigel P.C.

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SAR and Mode of Action of Novel Non-Nucleoside Inhibitors of Hepatitis C NS5b RNA Polymerase von Powers, Jay P, Piper, Derek E, Li, Yang, Mayorga, Veronica, Anzola, John, Chen, James M, Jaen, Juan C, Lee, Gary, Liu, Jinqian, Peterson, M. Greg, Tonn, George R, Ye, Qiuping, Walker, Nigel P. C, Wang, Zhulun

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A novel series of IKKβ inhibitors part I: Initial SAR studies of a HTS hit von Cushing, Timothy D., Baichwal, Vijay, Berry, Karen, Billedeau, Roland, Bordunov, Viola, Broka, Chris, Cardozo, Mario, Cheng, Peng, Clark, David, Dalrymple, Stacie, DeGraffenreid, Michael, Gill, Adrian, Hao, Xiaolin, Hawley, Ronald C., He, Xiao, Jaen, Juan C., Labadie, Sharada S., Labelle, Marc, Lehel, Csaba, Lu, Pu-Ping, McIntosh, Joel, Miao, Shichang, Parast, Camran, Shin, Youngsook, Sjogren, Eric B., Smith, Marie-Louise, Talamas, Francisco X., Tonn, George, Walker, Keith M., Walker, Nigel P.C., Wesche, Holger, Whitehead, Chris, Wright, Matt, Browner, Michelle F.

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Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH) von Min, Xiaoshan, Thibault, Stephen T, Porter, Amy C, Gustin, Darin J, Carlson, Timothy J, Xu, Haoda, Lindstrom, Michelle, Xu, Guifen, Uyeda, Craig, Ma, Zhihua, Li, Yihong, Kayser, Frank, Walker, Nigel P.C, Wang, Zhulun

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A novel series of IKKβ inhibitors part II: Description of a potent and pharmacologically active series of analogs von Cushing, Timothy D., Baichwal, Vijay, Berry, Karen, Billedeau, Roland, Bordunov, Viola, Broka, Chris, Browner, Michelle F., Cardozo, Mario, Cheng, Peng, Clark, David, Dalrymple, Stacie, DeGraffenreid, Michael, Gill, Adrian, Hao, Xiaolin, Hawley, Ronald C., He, Xiao, Labadie, Sharada S., Labelle, Marc, Lehel, Csaba, Lu, Pu-Ping, McIntosh, Joel, Miao, Shichang, Parast, Camran, Shin, Youngsook, Sjogren, Eric B., Smith, Marie-Louise, Talamas, Francisco X., Tonn, George, Walker, Keith M., Walker, Nigel P.C., Wesche, Holger, Whitehead, Chris, Wright, Matt, Jaen, Juan C.

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Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4 von Powers, Jay P., Li, Shyun, Jaen, Juan C., Liu, Jinqian, Walker, Nigel P.C., Wang, Zhulun, Wesche, Holger

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proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates von Chan, Joyce C.Y, Piper, Derek E, Cao, Qiong, Liu, Dongming, King, Chadwick, Wang, Wei, Tang, Jie, Liu, Qiang, Higbee, Jared, Xia, Zhen, Di, Yongmei, Shetterly, Susan, Arimura, Ziva, Salomonis, Heather, Romanow, William G, Thibault, Stephen T, Zhang, Richard, Cao, Ping, Yang, Xiao-Ping, Yu, Timothy, Lu, Mei, Retter, Marc W, Kwon, Gayle, Henne, Kirk, Pan, Oscar, Tsai, Mei-Mei, Fuchslocher, Bryna, Yang, Evelyn, Zhou, Lei, Lee, Ki Jeong, Daris, Mark, Sheng, Jackie, Wang, Yan, Shen, Wenyan D, Yeh, Wen-Chen, Emery, Maurice, Walker, Nigel P.C, Shan, Bei, Schwarz, Margrit, Jackson, Simon M

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Discovery and optimization of piperidyl benzamide derivatives as a novel class of 11β-HSD1 inhibitors von Rew, Yosup, McMinn, Dustin L., Wang, Zhulun, He, Xiao, Hungate, Randall W., Jaen, Juan C., Sudom, Athena, Sun, Daqing, Tu, Hua, Ursu, Stefania, Villemure, Elisia, Walker, Nigel P.C., Yan, Xuelei, Ye, Qiuping, Powers, Jay P.

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Distinctive molecular inhibition mechanisms for selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 von Tu, Hua, Powers, Jay P., Liu, Jinsong, Ursu, Stefania, Sudom, Athena, Yan, Xuelei, Xu, Haoda, Meininger, David, DeGraffenreid, Michael, He, Xiao, Jaen, Juan C., Sun, Daqing, Labelle, Marc, Yamamoto, Hiroshi, Shan, Bei, Walker, Nigel P.C., Wang, Zhulun

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The high-resolution crystal structure of human LCAT von Piper, Derek E, Romanow, William G, Gunawardane, Ruwanthi N, Fordstrom, Preston, Masterman, Stephanie, Pan, Oscar, Thibault, Stephen T, Zhang, Richard, Meininger, David, Schwarz, Margrit, Wang, Zhulun, King, Chadwick, Zhou, Mingyue, Walker, Nigel P C

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Crystal Structures of IRAK-4 Kinase in Complex with Inhibitors: A Serine/Threonine Kinase with Tyrosine as a Gatekeeper von Wang, Zhulun, Liu, Jinsong, Sudom, Athena, Ayres, Merrill, Li, Shyun, Wesche, Holger, Powers, Jay P., Walker, Nigel P.C.

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INT131: A Selective Modulator of PPARγ von Motani, Alykhan, Wang, Zhulun, Weiszmann, Jennifer, McGee, Lawrence R., Lee, Gary, Liu, Qingxiang, Staunton, Jocelyn, Fang, Zexu, Fuentes, Helen, Lindstrom, Michelle, Liu, Jinsong, Biermann, Donna H.T., Jaen, Juan, Walker, Nigel P.C., Learned, R. Marc, Chen, Jin-Long, Li, Yang

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Discovery of potent, selective, and orally bioavailable inhibitors of interleukin-1 receptor-associate kinase-4 von Wang, Zhulun, Sun, Daqing, Johnstone, Sheree, Cao, Zhaodan, Gao, Xiong, Jaen, Juan C., Liu, Jingqian, Lively, Sarah, Miao, Shichang, Sudom, Athena, Tomooka, Craig, Walker, Nigel P.C., Wright, Matthew, Yan, Xuelei, Ye, Qiuping, Powers, Jay P.

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BacMam production of active recombinant lecithin–cholesterol acyltransferase: Expression, purification and characterization von Romanow, William G., Piper, Derek E., Fordstrom, Preston, Thibault, Stephen, Zhou, Mingyue, Walker, Nigel P.C.

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Identification of a PPARδ agonist with partial agonistic activity on PPARγ von Connors, Richard V., Wang, Zhulun, Harrison, Martin, Zhang, Alex, Wanska, Malgorzata, Hiscock, Steve, Fox, Brian, Dore, Michael, Labelle, Marc, Sudom, Athena, Johnstone, Sheree, Liu, Jinsong, Walker, Nigel P.C., Chai, Anne, Siegler, Karen, Li, Yang, Coward, Peter

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Optimization of novel di-substituted cyclohexylbenzamide derivatives as potent 11β-HSD1 inhibitors von McMinn, Dustin L., Rew, Yosup, Sudom, Athena, Caille, Seb, DeGraffenreid, Michael, He, Xiao, Hungate, Randall, Jiang, Ben, Jaen, Juan, Julian, Lisa D., Kaizerman, Jacob, Novak, Perry, Sun, Daqing, Tu, Hua, Ursu, Stefania, Walker, Nigel P.C., Yan, Xuelei, Ye, Qiuping, Wang, Zhulun, Powers, Jay P.

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[2:1] and [2:2] cycloadducts from N-sulfonylamines and azomethines von Lender, Andreas, Walker, Nigel P.C., Schaumann, Ernst

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The high-resolution crystal structure of human LCAT1 von Piper, Derek E., Romanow, William G., Gunawardane, Ruwanthi N., Fordstrom, Preston, Masterman, Stephanie, Pan, Oscar, Thibault, Stephen T., Zhang, Richard, Meininger, David, Schwarz, Margrit, Wang, Zhulun, King, Chadwick, Zhou, Mingyue, Walker, NigelP.C.

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ChemInform Abstract: [2:1] and [2:2] Cycloadducts from N-Sulfonylamines and Azomethines von Lender, Andreas, Walker, Nigel P. C., Schaumann, Ernst

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