Rare variant contribution to human disease in 281,104 UK Biobank exomes von Wang, Quanli, Dhindsa, Ryan S., Carss, Keren, Harper, Andrew R., Nag, Abhishek, Tachmazidou, Ioanna, Vitsios, Dimitrios, Deevi, Sri V. V., Mackay, Alex, Muthas, Daniel, Hühn, Michael, Monkley, Susan, Olsson, Henric, Wasilewski, Sebastian, Smith, Katherine R., March, Ruth, Platt, Adam, Haefliger, Carolina, Petrovski, Slavé

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Collagen type III alpha 1 is a gastro-oesophageal reflux disease susceptibility gene and a male risk factor for hiatus hernia von Asling, B, Jirholt, J, Hammond, P, Knutsson, M, Walentinsson, A, Davidson, G, Agreus, L, Lehmann, A, Lagerstrom-Fermer, M

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Collagen type III alpha I is a gastro-oesophageal reflux disease susceptibility gene and a male risk factor for hiatus hernia von Åsling, B, Jirholt, J, Hammond, P, Knutsson, M, Walentinsson, A, Davidson, G, Agreus, L, Lehmann, A, Lagerström-Fermer, M

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Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences von Burren, Oliver S., Dhindsa, Ryan S., Deevi, Sri V. V., Wen, Sean, Nag, Abhishek, Mitchell, Jonathan, Hu, Fengyuan, Loesch, Douglas P., Smith, Katherine R., Razdan, Neetu, Olsson, Henric, Platt, Adam, Vitsios, Dimitrios, Wu, Qiang, Codd, Veryan, Nelson, Christopher P., Samani, Nilesh J., March, Ruth E., Wasilewski, Sebastian, Carss, Keren, Fabre, Margarete, Wang, Quanli, Pangalos, Menelas N., Petrovski, Slavé

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Cardiac biopsies reveal differences in transcriptomics between left and right ventricle in patients with or without diagnostic signs of heart failure von Frisk, Christoffer, Das, Sarbashis, Eriksson, Maria J., Walentinsson, Anna, Corbascio, Matthias, Hage, Camilla, Kumar, Chanchal, Ekström, Mattias, Maret, Eva, Persson, Hans, Linde, Cecilia, Persson, Bengt

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Critical differences in drug metabolic properties of human hepatic cellular models, including primary human hepatocytes, stem cell derived hepatocytes, and hepatoma cell lines von Kvist, Alexander J., Kanebratt, Kajsa P., Walentinsson, Anna, Palmgren, Henrik, O'Hara, Matthew, Björkbom, Anders, Andersson, Linda C., Ahlqvist, Marie, Andersson, Tommy B.

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Transcriptomics of cardiac biopsies reveals differences in patients with or without diagnostic parameters for heart failure with preserved ejection fraction von Das, Sarbashis, Frisk, Christoffer, Eriksson, Maria J., Walentinsson, Anna, Corbascio, Matthias, Hage, Camilla, Kumar, Chanchal, Asp, Michaela, Lundeberg, Joakim, Maret, Eva, Persson, Hans, Linde, Cecilia, Persson, Bengt

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Epigenetic modulators link mitochondrial redox homeostasis to cardiac function in a sex-dependent manner von ElBeck, Zaher, Hossain, Mohammad Bakhtiar, Siga, Humam, Oskolkov, Nikolay, Karlsson, Fredrik, Lindgren, Julia, Walentinsson, Anna, Koppenhöfer, Dominique, Jarvis, Rebecca, Bürli, Roland, Jamier, Tanguy, Franssen, Elske, Firth, Mike, Degasperi, Andrea, Bendtsen, Claus, Menzies, Robert I., Streckfuss-Bömeke, Katrin, Kohlhaas, Michael, Nickel, Alexander G., Lund, Lars H., Maack, Christoph, Végvári, Ákos, Betsholtz, Christer

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Novel genetic marker for dilated end stage oesophagus and oesophageal adenocarcinoma risk? Response von Asling, B, Jirholt, J, Hammond, P, Knutsson, M, Walentinsson, A, Davidson, G, Agreus, L, Lehmann, A, Lagerstrom-Fermer, M

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Phosphoproteomics of PLN R14del heart tissue reveals major myocyte degenerate phenotype, and is attenuated by PLN antisense treatment in vitro von Deiman, F E, Davidsson, P, Spater, D, Linders, A N, Dias, I B, Arevalo Gomez, K F, Esquivel-Gaytan, A, Andrysiak, K, Walentinsson, A, Ahlstrom, C, Mullick, A E, Hansson, K M, Bomer, N, Grote Beverborg, N, Van Der Meer, P

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Vasculoprotective properties of plasma lipoproteins from brown bears (Ursus arctos) von Pedrelli, Matteo, Parini, Paolo, Kindberg, Jonas, Arnemo, Jon M., Bjorkhem, Ingemar, Aasa, Ulrika, Westerståhl, Maria, Walentinsson, Anna, Pavanello, Chiara, Turri, Marta, Calabresi, Laura, Öörni, Katariina, Camejo, Gérman, Fröbert, Ole, Hurt-Camejo, Eva

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MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity von Tyka, Karolina, Jörns, Anne, Dunst, Alessia, Tang, Yadi, Bryde, Tenna Holgersen, Mehmeti, Ilir, Walentinsson, Anna, Marselli, Lorella, Cnop, Miriam, Tyrberg, Björn, Marzec, Michal T., Gurgul-Convey, Ewa

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Identification of Proteins Associated with the Early Restoration of Insulin Sensitivity After Biliopancreatic Diversion von Karlsson, Cecilia, Wallenius, Kristina, Walentinsson, Anna, Greasley, Peter J, Miliotis, Tasso, Hammar, Mårten, Iaconelli, Amerigo, Tapani, Sofia, Raffaelli, Marco, Mingrone, Geltrude, Carlsson, Björn

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P3247Polymorphisms of the ALOX5AP gene (5-lipoxygenase activating protein) are associated with increased cardiovascular risk in patients with acute coronary syndrome: Analysis of P... von Balendran, C., Eriksson, N., Whatling, C., Walentinsson, A., Skrtic, S., Akerblom, A., Jensevik, K., Wallentin, L.

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The inducible β5i proteasome subunit contributes to proinsulin degradation in GRP94 deficient β cells and is overexpressed in type 2 diabetes pancreatic islets von Khilji, Muhammad Saad, Bresson, Sophie Emilie, Verstappen, Danielle, Pihl, Celina, Andersen, Phillip Alexander Keller, Agergaard, Jette Bach, Dahlby, Tina, Holgersen Bryde, Tenna, Klindt, Kristian, Nielsen, Christian Kronborg, Walentinsson, Anna, Zivkovic, Dusan, Bousquet, Marie-Pierre, Tyrberg, Bjørn, Richardson, Sarah J, Morgan, Noel G, Mandrup-Poulsen, Thomas, Marzec, Michal Tomasz

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An epigenetic circuit linking oxidative stress and DNA hydroxymethylation in heart failure von Elbeck, Z, Hossain, M.B, Franzen, O, Siga, H, Karlsson, F, Walentinsson, A, Moosmang, S, Milting, H, Lund, L.H, Vegvari, A, Knoll, R

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VENTHEART is required for cardiomyocyte specification and function von Jonsson Boezelman, M, Dashi, A, Tan, W, Pan, B, Ilmari, A.M, Tiang, Z, Hartman, R.J.G, Anen, C.G.O, Liu, Z, Wu, J.J, Bin, G, Lim, B, Walentinsson, A, Foo, R.S

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Athero-protective properties of plasma lipoproteins from brown bears (URSUS ARCTOS) during hibernation and active state von Pedrelli, M., Parini, P., Kindberg, J., Arnemo, J.M., Björkhem, I., Aasa, U., Westerstahl, M., Walentinsson, A., Öörni, K., Camejo, G., Frobert, O., Hurt-Camejo, E.

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Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio Tests von Frånberg, Mattias, Gertow, Karl, Hamsten, Anders, Lagergren, Jens, Sennblad, Bengt

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4-aminobutyrate aminotransferase (ABAT): genetic and pharmacological evidence for an involvement in gastro esophageal reflux disease von Jirholt, Johan, Asling, Bengt, Hammond, Paul, Davidson, Geoffrey, Knutsson, Mikael, Walentinsson, Anna, Jensen, Jörgen M, Lehmann, Anders, Agreus, Lars, Lagerström-Fermer, Maria

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