Mechanisms of Tamoxifen Resistance: Increased Estrogen Receptor-HER2/neu Cross-Talk in ER/HER2–Positive Breast Cancer von Shou, Jiang, Massarweh, Suleiman, Osborne, C. Kent, Wakeling, Alan E., Ali, Simale, Weiss, Heidi, Schiff, Rachel

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Elevated Levels of Epidermal Growth Factor Receptor/c-erbB2 Heterodimers Mediate an Autocrine Growth Regulatory Pathway in Tamoxifen-Resistant MCF-7 Cells von Knowlden, Janice M, Hutcheson, Iain R, Jones, Helen E, Madden, Tracieann, Gee, Julia M. W, Harper, Maureen E, Barrow, Denise, Wakeling, Alan E, Nicholson, Robert I

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ZD1839 (Iressa): An orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy von WAKELING, Alan E, GUY, Simon P, WOODBURN, Jim R, ASHTON, Susan E, CURRY, Brenda J, BARKER, Andrew J, GIBSON, Keith H

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Mechanisms of tumor regression and resistance to estrogen deprivation and fulvestrant in a model of estrogen receptor- positive, HER-2/neu-positive breast cancer von MASSARWEH, Suleiman, OSBORNE, C. Kent, SHOU JIANG, WAKELING, Alan E, RIMAWI, Mothaffar, MOHSIN, Syed K, HILSENBECK, Susan, SCHIFF, Rachel

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Epidermal growth factor receptor tyrosine kinase inhibitors von Wakeling, Alan E

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Increased constitutive activity of PKB/Akt in tamoxifen resistant breast cancer MCF-7 cells von JORDAN, Nicola J, GEE, Julia M. W, BARROW, Denise, WAKELING, Alan E, NICHOLSON, Robert I

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Comparison of the short-term biological effects of 7α-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)-nonyl]estra-1,3,5, (10)-triene-3,17β-diol (faslodex) versus tamoxifen in postmenopaus... von ROBERTSON, John F, NICHOLSON, Robert I, MORRIS, Charles, DIXON, Michael, BUNDRED, Nigel J, ANDERSON, Elizabeth, RAYTER, Zenon, DOWSETT, Mitchell, FOX, John N, GEE, Julia M. W, WEBSTER, Alan, WAKELING, Alan E

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Oestrogen receptor-mediated modulation of the EGFR/MAPK pathway in tamoxifen-resistant MCF-7 cells von HUTCHESON, Iain R, KNOWLDEN, Janice M, MADDEN, Tracie-Ann, BARROW, Denise, GEE, Julia M. W, WAKELING, Alan E, NICHOLSON, Robert I

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Activation of BAD by Therapeutic Inhibition of Epidermal Growth Factor Receptor and Transactivation by Insulin-like Growth Factor Receptor von Gilmore, Andrew P., Valentijn, Anthony J., Wang, Pengbo, Ranger, Ann M., Bundred, Nigel, O'Hare, Michael J., Wakeling, Alan, Korsmeyer, Stanley J., Streuli, Charles H.

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A potent specific pure antiestrogen with clinical potential von WAKELING, A. E, DUKES, M, BOWLER, J

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Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile and invasive phenotype: inhibition by gefitinib ('Iressa', ZD1839) von Hiscox, Stephen, Morgan, Liam, Barrow, Denise, Dutkowskil, Carol, Wakeling, Alan, Nicholson, Robert I

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ICI 182,780 (Faslodex) : Development of a novel, pure antiestrogen von HOWELL, A, OSBORNE, C. K, MORRIS, C, WAKELING, A. E

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The future of new pure antiestrogens in clinical breast cancer von WAKELING, A. E

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Inhibitors of growth factor signalling von Wakeling, A E

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Growth factors and their receptors: new targets for prostate cancer therapy von Barton, Jeremy, Blackledge, George, Wakeling, Alan

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Multiple responses to EGF receptor activation and their abrogation by a specific EGF receptor tyrosine kinase inhibitor von Harper, Maureen E., Goddard, Lindy, Glynne-Jones, Eve, Assender, Jean, Dutkowski, Carol M., Barrow, Denise, Dewhurst, Odette L., Wakeling, Alan E., Nicholson, Robert I.

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Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation von Oberhammer, F., Wilson, J.W., Dive, C., Morris, I.D., Hickman, J.A., Wakeling, A.E., Walker, P.R., Sikorska, M.

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Points of action of estrogen antagonists and a calmodulin antagonist within the MCF-7 human breast cancer cell cycle von MUSGROVE, E. A, WAKELING, A. E, SUTHERLAND, R. L

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Comparison of the Effects of a Pure Steroidal antiestrogen With Those of Tamoxifen in a Model of Human Breast Cancer von Osborne, C. Kent, Coronado-Heinsohn, Ester B., Hilsenbeck, Susan G., McCue, Bryant L., Wakeling, Alan E., McCleland, Richard A., Manning, David L., Nicholson, Robert I.

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New EGF‐R selective tyrosine kinase inhibitor reveals variable growth responses in prostate carcinoma cell lines PC‐3 and DU‐145 von Jones, Helen E., Dutkowski, Carol M., Barrow, Denise, Harper, Maureen E., Wakeling, Alan E., Nicholson, Robert I.

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