T cell-intrinsic IL-1R signaling licenses effector cytokine production by memory CD4 T cells von Jain, Aakanksha, Song, Ran, Wakeland, Edward K., Pasare, Chandrashekhar

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RAD51 interconnects between DNA replication, DNA repair and immunity von Bhattacharya, Souparno, Srinivasan, Kalayarasan, Abdisalaam, Salim, Su, Fengtao, Raj, Prithvi, Dozmorov, Igor, Mishra, Ritu, Wakeland, Edward K, Ghose, Subroto, Mukherjee, Shibani, Asaithamby, Aroumougame

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IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility von Song, Ran, Gao, Yajing, Dozmorov, Igor, Malladi, Venkat, Saha, Irene, McDaniel, Margaret M., Parameswaran, Sreeja, Liang, Chaoying, Arana, Carlos, Zhang, Bo, Wakeland, Benjamin, Zhou, Jinchun, Weirauch, Matthew T., Kottyan, Leah C., Wakeland, Edward K., Pasare, Chandrashekhar

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Differential outcome of TRIF-mediated signaling in TLR4 and TLR3 induced DC maturation von Hu, Wei, Jain, Aakanksha, Gao, Yajing, Dozmorov, Igor M., Mandraju, Rajakumar, Wakeland, Edward K., Pasare, Chandrashekhar

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Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice von Hasan, Maroof, Dobbs, Nicole, Khan, Shaheen, White, Michael A, Wakeland, Edward K, Li, Quan-Zhen, Yan, Nan

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Distinct patterns of innate immune activation by clinical isolates of respiratory syncytial virus von Levitz, Ruth, Gao, Yajing, Dozmorov, Igor, Song, Ran, Wakeland, Edward K, Kahn, Jeffrey S

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SLE peripheral blood B cell, T cell and myeloid cell transcriptomes display unique profiles and each subset contributes to the interferon signature von Becker, Amy M, Dao, Kathryn H, Han, Bobby Kwanghoon, Kornu, Roger, Lakhanpal, Shuchi, Mobley, Angela B, Li, Quan-Zhen, Lian, Yun, Wu, Tianfu, Reimold, Andreas M, Olsen, Nancy J, Karp, David R, Chowdhury, Fatema Z, Farrar, J David, Satterthwaite, Anne B, Mohan, Chandra, Lipsky, Peter E, Wakeland, Edward K, Davis, Laurie S

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Obesity-Associated Autoantibody Production Requires AIM to Retain the Immunoglobulin M Immune Complex on Follicular Dendritic Cells von Arai, Satoko, Maehara, Natsumi, Iwamura, Yoshihiro, Honda, Shin-ichiro, Nakashima, Katsuhiko, Kai, Toshihiro, Ogishi, Masato, Morita, Kumiko, Kurokawa, Jun, Mori, Mayumi, Motoi, Yuji, Miyake, Kensuke, Matsuhashi, Nobuyuki, Yamamura, Ken-ichi, Ohara, Osamu, Shibuya, Akira, Wakeland, Edward K., Li, Quan-Zhen, Miyazaki, Toru

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A Tlr7 Translocation Accelerates Systemic Autoimmunity in Murine Lupus von Subramanian, Srividya, Tus, Katalin, Li, Quan-Zhen, Wang, Andrew, Tian, Xiang-Hong, Zhou, Jinchun, Liang, Chaoying, Bartov, Guy, McDaniel, Lisa D., Zhou, Xin J., Schultz, Roger A., Wakeland, Edward K.

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Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity von Raj, Prithvi, Rai, Ekta, Song, Ran, Khan, Shaheen, Wakeland, Benjamin E, Viswanathan, Kasthuribai, Arana, Carlos, Liang, Chaoying, Zhang, Bo, Dozmorov, Igor, Carr-Johnson, Ferdicia, Mitrovic, Mitja, Wiley, Graham B, Kelly, Jennifer A, Lauwerys, Bernard R, Olsen, Nancy J, Cotsapas, Chris, Garcia, Christine K, Wise, Carol A, Harley, John B, Nath, Swapan K, James, Judith A, Jacob, Chaim O, Tsao, Betty P, Pasare, Chandrashekhar, Karp, David R, Li, Quan Zhen, Gaffney, Patrick M, Wakeland, Edward K

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Complete genome analysis of three Acinetobacter baumannii clinical isolates in China for insight into the diversification of drug resistance elements von Zhu, Lingxiang, Yan, Zhongqiang, Zhang, Zhaojun, Zhou, Qiming, Zhou, Jinchun, Wakeland, Edward K, Fang, Xiangdong, Xuan, Zhenyu, Shen, Dingxia, Li, Quan-Zhen

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Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians von Molineros, Julio E, Looger, Loren L, Kim, Kwangwoo, Okada, Yukinori, Terao, Chikashi, Sun, Celi, Zhou, Xu-Jie, Raj, Prithvi, Kochi, Yuta, Suzuki, Akari, Akizuki, Shuji, Nakabo, Shuichiro, Bang, So-Young, Lee, Hye-Soon, Kang, Young Mo, Suh, Chang-Hee, Chung, Won Tae, Park, Yong-Beom, Choe, Jung-Yoon, Shim, Seung-Cheol, Lee, Shin-Seok, Zuo, Xiaoxia, Yamamoto, Kazuhiko, Li, Quan-Zhen, Shen, Nan, Porter, Lauren L, Harley, John B, Chua, Kek Heng, Zhang, Hong, Wakeland, Edward K, Tsao, Betty P, Bae, Sang-Cheol, Nath, Swapan K

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Risk factors for ANA positivity in healthy persons von Li, Quan-Zhen, Karp, David R, Quan, Jiexia, Branch, Valerie K, Zhou, Jinchun, Lian, Yun, Chong, Benjamin F, Wakeland, Edward K, Olsen, Nancy J

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Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus von Raj, Prithvi, Song, Ran, Zhu, Honglin, Riediger, Linley, Jun, Dong-Jae, Liang, Chaoying, Arana, Carlos, Zhang, Bo, Gao, Yajing, Wakeland, Benjamin E, Dozmorov, Igor, Zhou, Jinchun, Kelly, Jennifer A, Lauwerys, Bernard R, Guthridge, Joel M, Olsen, Nancy J, Nath, Swapan K, Pasare, Chandrashekhar, van Oers, Nicolai, Gilkeson, Gary, Tsao, Betty P, Gaffney, Patrick M, Gregersen, Peter K, James, Judith A, Zuo, Xiaoxia, Karp, David R, Li, Quan-Zhen, Wakeland, Edward K

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Yaa autoimmune phenotypes are conferred by overexpression of TLR7 von Fairhurst, Anna-Marie, Hwang, Sun-hee, Wang, Andrew, Tian, Xiang-Hong, Boudreaux, Christopher, Zhou, Xin J, Casco, Jose, Li, Quan-Zhen, Connolly, John E, Wakeland, Edward K

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B cell TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in systemic lupus erythematosus-prone mice von Hwang, Sun-Hee, Lee, Huiyin, Yamamoto, Miwako, Jones, Leigh A, Dayalan, Jivanaah, Hopkins, Richard, Zhou, Xin J, Yarovinsky, Felix, Connolly, John E, Curotto de Lafaille, Maria A, Wakeland, Edward K, Fairhurst, Anna-Marie

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Distinct autoantibody profiles across checkpoint inhibitor types and toxicities von Mu-Mosley, Hong, von Itzstein, Mitchell S., Fattah, Farjana, Liu, Jialiang, Zhu, Chengsong, Xie, Yang, Wakeland, Edward K., Park, Jason Y., Kahl, Brad S., Diefenbach, Catherine S., Gerber, David E.

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RNA sensing by conventional dendritic cells is central to the development of lupus nephritis von Celhar, Teja, Hopkins, Richard, Thornhill, Susannah I., De Magalhaes, Raquel, Hwang, Sun-Hee, Lee, Hui-Yin, Yasuga, Hiroko, Jones, Leigh A., Casco, Jose, Lee, Bernett, Thamboo, Thomas P., Zhou, Xin J., Poidinger, Michael, Connolly, John E., Wakeland, Edward K., Fairhurst, Anna-Marie

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Genomic Heterogeneity of Methicillin Resistant Staphylococcus aureus Associated with Variation in Severity of Illness among Children with Acute Hematogenous Osteomyelitis von Gaviria-Agudelo, Claudia, Aroh, Chukwuemika, Tareen, Naureen, Wakeland, Edward K, Kim, MinSoo, Copley, Lawson A

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Delineating the Genetic Basis of Systemic Lupus Erythematosus von Wakeland, Edward K, Liu, Kui, Graham, Robert R, Behrens, Timothy W

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