Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease von Horii, Mariko, Li, Yingchun, Wakeland, Anna K., Pizzo, Donald P., Nelson, Katharine K., Sabatini, Karen, Laurent, Louise Chang, Liu, Ying, Parast, Mana M.

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Hypoxia Directs Human Extravillous Trophoblast Differentiation in a Hypoxia-Inducible Factor–Dependent Manner von Wakeland, Anna K, Soncin, Francesca, Moretto-Zita, Matteo, Chang, Ching-Wen, Horii, Mariko, Pizzo, Don, Nelson, Katharine K, Laurent, Louise C, Parast, Mana M

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Trophoblast lineage specification, differentiation and their regulation by oxygen tension von Chang, Ching-Wen, Wakeland, Anna K, Parast, Mana M

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Comparative analysis of mouse and human placentae across gestation reveals species-specific regulators of placental development von Soncin, Francesca, Khater, Marwa, To, Cuong, Pizzo, Donald, Farah, Omar, Wakeland, Anna, Arul Nambi Rajan, Kanaga, Nelson, Katharine K, Chang, Ching-Wen, Moretto-Zita, Matteo, Natale, David R, Laurent, Louise C, Parast, Mana M

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Yaa autoimmune phenotypes are conferred by overexpression of TLR7 von Fairhurst, Anna-Marie, Hwang, Sun-hee, Wang, Andrew, Tian, Xiang-Hong, Boudreaux, Christopher, Zhou, Xin J, Casco, Jose, Li, Quan-Zhen, Connolly, John E, Wakeland, Edward K

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Toll‐Like Receptor 9 Deficiency Breaks Tolerance to RNA‐Associated Antigens and Up‐Regulates Toll‐Like Receptor 7 Protein in Sle1 Mice von Celhar, Teja, Yasuga, Hiroko, Lee, Hui Yin, Zharkova, Olga, Tripathi, Shubhita, Thornhill, Susannah I., Lu, Hao K., Au, Bijin, Lim, Lina H. K., Thamboo, Thomas P., Akira, Shizuo, Wakeland, Edward K., Connolly, John E., Fairhurst, Anna‐Marie

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B cell TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in systemic lupus erythematosus-prone mice von Hwang, Sun-Hee, Lee, Huiyin, Yamamoto, Miwako, Jones, Leigh A, Dayalan, Jivanaah, Hopkins, Richard, Zhou, Xin J, Yarovinsky, Felix, Connolly, John E, Curotto de Lafaille, Maria A, Wakeland, Edward K, Fairhurst, Anna-Marie

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KLF13 promotes SLE pathogenesis by modifying chromatin accessibility of key proinflammatory cytokine genes von Wang, Andrew, Fairhurst, Anna-Marie, Liu, Kui, Wakeland, Benjamin, Barnes, Spencer, Malladi, Venkat S., Viswanathan, Kasthuribai, Arana, Carlos, Dozmorov, Igor, Singhar, Amrita, Du, Yong, Imam, Marjaan, Moses, Angela, Chen, Christian, Sunkavalli, Ashwini, Casco, Jose, Rakheja, Dinesh, Li, Quan-Zhen, Mohan, Chandra, Clayberger, Carol, Wakeland, Edward K., Khan, Shaheen

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RNA sensing by conventional dendritic cells is central to the development of lupus nephritis von Celhar, Teja, Hopkins, Richard, Thornhill, Susannah I., De Magalhaes, Raquel, Hwang, Sun-Hee, Lee, Hui-Yin, Yasuga, Hiroko, Jones, Leigh A., Casco, Jose, Lee, Bernett, Thamboo, Thomas P., Zhou, Xin J., Poidinger, Michael, Connolly, John E., Wakeland, Edward K., Fairhurst, Anna-Marie

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CXCR4/CXCL12 Hyperexpression Plays a Pivotal Role in the Pathogenesis of Lupus von Wang, Andrew, Fairhurst, Anna-Marie, Tus, Katalin, Subramanian, Srividya, Liu, Yang, Lin, Fangming, Igarashi, Peter, Zhou, Xin J, Batteux, Frederic, Wong, Donald, Wakeland, Edward K, Mohan, Chandra

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Type I Interferons Produced by Resident Renal Cells May Promote End-Organ Disease in Autoantibody-Mediated Glomerulonephritis von Fairhurst, Anna-Marie, Xie, Chun, Fu, Yuyang, Wang, Andrew, Boudreaux, Christopher, Zhou, Xin J, Cibotti, Ricardo, Coyle, Anthony, Connolly, John E, Wakeland, Edward K, Mohan, Chandra

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Autoantibody profiling to identify individuals at risk for systemic lupus erythematosus von Wandstrat, Amy E., Carr-Johnson, Ferdicia, Branch, Valerie, Gray, Hillery, Fairhurst, Anna-Marie, Reimold, Andreas, Karp, David, Wakeland, Edward K., Olsen, Nancy J.

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Systemic IFN-α drives kidney nephritis in B6.Sle123 mice von Fairhurst, Anna-Marie, Mathian, Alexis, Connolly, John E, Wang, Andrew, Gray, Hillery F, George, Tiffany A, Boudreaux, Christopher D, Zhou, Xin J, Li, Quan-Zhen, Koutouzov, Sophie, Banchereau, Jacques, Wakeland, Edward K

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Fatty Acid Amide Hydrolase Regulates Peripheral B Cell Receptor Revision, Polyreactivity, and B1 Cells in Lupus von Pathak, Simanta, Kumar, Kirthi Raman, Kanta, Hasna, Carr-Johnson, Ferdicia, Han, Jie, Bashmakov, Anna, Faure, Lionel, Ding, Huihua, Vanarsa, Kamala, Khan, Shaheen, Li, Quan-Zhen, Chapman, Kent, Wakeland, Edward K, Mohan, Chandra

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Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans von Liu, Kui, Li, Quan-Zhen, Delgado-Vega, Angelica M, Abelson, Anna-Karin, Sánchez, Elena, Kelly, Jennifer A, Li, Li, Liu, Yang, Zhou, Jinchun, Yan, Mei, Ye, Qiu, Liu, Shenxi, Xie, Chun, Zhou, Xin J, Chung, Sharon A, Pons-Estel, Bernardo, Witte, Torsten, de Ramón, Enrique, Bae, Sang-Cheol, Barizzone, Nadia, Sebastiani, Gian Domenico, Merrill, Joan T, Gregersen, Peter K, Gilkeson, Gary G, Kimberly, Robert P, Vyse, Timothy J, Kim, Il, D'Alfonso, Sandra, Martin, Javier, Harley, John B, Criswell, Lindsey A, Wakeland, Edward K, Alarcón-Riquelme, Marta E, Mohan, Chandra

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The expression of CXCR4/CXCL12 determines subsets of patients in systemic lupus erythematosus von Guilpain, Philippe, Wang, Andrew, Chong, Benjamin F, Chouzenoux, Sandrine, Guillevin, Loic, Zhou, Xin J, Lin, Fangming, Fairhurst, Anna-Marie, Boudreaux, Christopher, Roux, Christian, Wakeland, Edward K, Davis, Laurie, Batteux, Frederic, Mohan, Chandra

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B cell-TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in SLE-prone mice von Hwang, Sun-Hee, Lee, Huiyin, Yamamoto, Miwako, Jones, Leigh A, Dayalan, Jivanaah, Hopkins, Richard, Zhou, Xin J, Yarovinsky, Felix, Connolly, John E, de Lafaille, Maria A Curotto, Wakeland, Edward K., Fairhurst, Anna-Marie

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Systemic IFN‐α drives kidney nephritis in B6. Sle123 mice von Fairhurst, Anna‐Marie, Mathian, Alexis, Connolly, John E., Wang, Andrew, Gray, Hillery F., George, Tiffany A., Boudreaux, Christopher D., Zhou, Xin J., Li, Quan‐Zhen, Koutouzov, Sophie, Banchereau, Jacques, Wakeland, Edward K.

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Dysregulated expression of CXCR4/CXCL12 in subsets of patients with systemic lupus erythematosus von Wang, Andrew, Guilpain, Philippe, Chong, Benjamin F., Chouzenoux, Sandrine, Guillevin, Loïc, Du, Yong, Zhou, Xin J., Lin, Fangming, Fairhurst, Anna‐Marie, Boudreaux, Christopher, Roux, Christian, Wakeland, Edward K., Davis, Laurie S., Batteux, Frederic, Mohan, Chandra

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