Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease von Horii, Mariko, Li, Yingchun, Wakeland, Anna K., Pizzo, Donald P., Nelson, Katharine K., Sabatini, Karen, Laurent, Louise Chang, Liu, Ying, Parast, Mana M.

Volltext

Hypoxia Directs Human Extravillous Trophoblast Differentiation in a Hypoxia-Inducible Factor–Dependent Manner von Wakeland, Anna K, Soncin, Francesca, Moretto-Zita, Matteo, Chang, Ching-Wen, Horii, Mariko, Pizzo, Don, Nelson, Katharine K, Laurent, Louise C, Parast, Mana M

Volltext

Trophoblast lineage specification, differentiation and their regulation by oxygen tension von Chang, Ching-Wen, Wakeland, Anna K, Parast, Mana M

Volltext

Type I Interferons Produced by Resident Renal Cells May Promote End-Organ Disease in Autoantibody-Mediated Glomerulonephritis von Fairhurst, Anna-Marie, Xie, Chun, Fu, Yuyang, Wang, Andrew, Boudreaux, Christopher, Zhou, Xin J, Cibotti, Ricardo, Coyle, Anthony, Connolly, John E, Wakeland, Edward K, Mohan, Chandra

Volltext

CXCR4/CXCL12 Hyperexpression Plays a Pivotal Role in the Pathogenesis of Lupus von Wang, Andrew, Fairhurst, Anna-Marie, Tus, Katalin, Subramanian, Srividya, Liu, Yang, Lin, Fangming, Igarashi, Peter, Zhou, Xin J, Batteux, Frederic, Wong, Donald, Wakeland, Edward K, Mohan, Chandra

Volltext

Systemic IFN-α drives kidney nephritis in B6.Sle123 mice von Fairhurst, Anna-Marie, Mathian, Alexis, Connolly, John E, Wang, Andrew, Gray, Hillery F, George, Tiffany A, Boudreaux, Christopher D, Zhou, Xin J, Li, Quan-Zhen, Koutouzov, Sophie, Banchereau, Jacques, Wakeland, Edward K

Volltext

Dysregulated expression of CXCR4/CXCL12 in subsets of patients with systemic lupus erythematosus von Wang, Andrew, Guilpain, Philippe, Chong, Benjamin F., Chouzenoux, Sandrine, Guillevin, Loïc, Du, Yong, Zhou, Xin J., Lin, Fangming, Fairhurst, Anna‐Marie, Boudreaux, Christopher, Roux, Christian, Wakeland, Edward K., Davis, Laurie S., Batteux, Frederic, Mohan, Chandra

Volltext

Comparative analysis of mouse and human placentae across gestation reveals species-specific regulators of placental development von Soncin, Francesca, Khater, Marwa, To, Cuong, Pizzo, Donald, Farah, Omar, Wakeland, Anna, Arul Nambi Rajan, Kanaga, Nelson, Katharine K, Chang, Ching-Wen, Moretto-Zita, Matteo, Natale, David R, Laurent, Louise C, Parast, Mana M

Volltext

Yaa autoimmune phenotypes are conferred by overexpression of TLR7 von Fairhurst, Anna-Marie, Hwang, Sun-hee, Wang, Andrew, Tian, Xiang-Hong, Boudreaux, Christopher, Zhou, Xin J, Casco, Jose, Li, Quan-Zhen, Connolly, John E, Wakeland, Edward K

Volltext

Toll‐Like Receptor 9 Deficiency Breaks Tolerance to RNA‐Associated Antigens and Up‐Regulates Toll‐Like Receptor 7 Protein in Sle1 Mice von Celhar, Teja, Yasuga, Hiroko, Lee, Hui Yin, Zharkova, Olga, Tripathi, Shubhita, Thornhill, Susannah I., Lu, Hao K., Au, Bijin, Lim, Lina H. K., Thamboo, Thomas P., Akira, Shizuo, Wakeland, Edward K., Connolly, John E., Fairhurst, Anna‐Marie

Volltext

B cell TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in systemic lupus erythematosus-prone mice von Hwang, Sun-Hee, Lee, Huiyin, Yamamoto, Miwako, Jones, Leigh A, Dayalan, Jivanaah, Hopkins, Richard, Zhou, Xin J, Yarovinsky, Felix, Connolly, John E, Curotto de Lafaille, Maria A, Wakeland, Edward K, Fairhurst, Anna-Marie

Volltext

KLF13 promotes SLE pathogenesis by modifying chromatin accessibility of key proinflammatory cytokine genes von Wang, Andrew, Fairhurst, Anna-Marie, Liu, Kui, Wakeland, Benjamin, Barnes, Spencer, Malladi, Venkat S., Viswanathan, Kasthuribai, Arana, Carlos, Dozmorov, Igor, Singhar, Amrita, Du, Yong, Imam, Marjaan, Moses, Angela, Chen, Christian, Sunkavalli, Ashwini, Casco, Jose, Rakheja, Dinesh, Li, Quan-Zhen, Mohan, Chandra, Clayberger, Carol, Wakeland, Edward K., Khan, Shaheen

Volltext

RNA sensing by conventional dendritic cells is central to the development of lupus nephritis von Celhar, Teja, Hopkins, Richard, Thornhill, Susannah I., De Magalhaes, Raquel, Hwang, Sun-Hee, Lee, Hui-Yin, Yasuga, Hiroko, Jones, Leigh A., Casco, Jose, Lee, Bernett, Thamboo, Thomas P., Zhou, Xin J., Poidinger, Michael, Connolly, John E., Wakeland, Edward K., Fairhurst, Anna-Marie

Volltext

Autoantibody profiling to identify individuals at risk for systemic lupus erythematosus von Wandstrat, Amy E., Carr-Johnson, Ferdicia, Branch, Valerie, Gray, Hillery, Fairhurst, Anna-Marie, Reimold, Andreas, Karp, David, Wakeland, Edward K., Olsen, Nancy J.

Volltext

Fatty Acid Amide Hydrolase Regulates Peripheral B Cell Receptor Revision, Polyreactivity, and B1 Cells in Lupus von Pathak, Simanta, Kumar, Kirthi Raman, Kanta, Hasna, Carr-Johnson, Ferdicia, Han, Jie, Bashmakov, Anna, Faure, Lionel, Ding, Huihua, Vanarsa, Kamala, Khan, Shaheen, Li, Quan-Zhen, Chapman, Kent, Wakeland, Edward K, Mohan, Chandra

Volltext

Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans von Liu, Kui, Li, Quan-Zhen, Delgado-Vega, Angelica M, Abelson, Anna-Karin, Sánchez, Elena, Kelly, Jennifer A, Li, Li, Liu, Yang, Zhou, Jinchun, Yan, Mei, Ye, Qiu, Liu, Shenxi, Xie, Chun, Zhou, Xin J, Chung, Sharon A, Pons-Estel, Bernardo, Witte, Torsten, de Ramón, Enrique, Bae, Sang-Cheol, Barizzone, Nadia, Sebastiani, Gian Domenico, Merrill, Joan T, Gregersen, Peter K, Gilkeson, Gary G, Kimberly, Robert P, Vyse, Timothy J, Kim, Il, D'Alfonso, Sandra, Martin, Javier, Harley, John B, Criswell, Lindsey A, Wakeland, Edward K, Alarcón-Riquelme, Marta E, Mohan, Chandra

Volltext

Role of autocrine bone morphogenetic protein signaling in trophoblast stem cells von Au, Jennie, Requena, Daniela F., Rishik, Hannah, Kallol, Sampada, Tekkatte, Chandana, Farah, Omar A., Kittle, Ryan, Meads, Morgan, Wakeland, Anna, Soncin, Francesca

Volltext

BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a ΔNp63+ cytotrophoblast stem cell state von Li, Yingchun, Moretto-Zita, Matteo, Soncin, Francesca, Wakeland, Anna, Wolfe, Lynlee, Leon-Garcia, Sandra, Pandian, Raj, Pizzo, Donald, Cui, Li, Nazor, Kristopher, Loring, Jeanne F, Crum, Christopher P, Laurent, Louise C, Parast, Mana M

Volltext

The expression of CXCR4/CXCL12 determines subsets of patients in systemic lupus erythematosus von Guilpain, Philippe, Wang, Andrew, Chong, Benjamin F, Chouzenoux, Sandrine, Guillevin, Loic, Zhou, Xin J, Lin, Fangming, Fairhurst, Anna-Marie, Boudreaux, Christopher, Roux, Christian, Wakeland, Edward K, Davis, Laurie, Batteux, Frederic, Mohan, Chandra

Volltext

B cell-TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in SLE-prone mice von Hwang, Sun-Hee, Lee, Huiyin, Yamamoto, Miwako, Jones, Leigh A, Dayalan, Jivanaah, Hopkins, Richard, Zhou, Xin J, Yarovinsky, Felix, Connolly, John E, de Lafaille, Maria A Curotto, Wakeland, Edward K., Fairhurst, Anna-Marie

Volltext