Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma von Ben-Batalla, Isabel, Schultze, Alexander, Wroblewski, Mark, Erdmann, Robert, Heuser, Michael, Waizenegger, Jonas S., Riecken, Kristoffer, Binder, Mascha, Schewe, Denis, Sawall, Stefanie, Witzke, Victoria, Cubas-Cordova, Miguel, Janning, Melanie, Wellbrock, Jasmin, Fehse, Boris, Hagel, Christian, Krauter, Jürgen, Ganser, Arnold, Lorens, James B., Fiedler, Walter, Carmeliet, Peter, Pantel, Klaus, Bokemeyer, Carsten, Loges, Sonja

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Treatment of refractory acute myeloid leukaemia during pregnancy with venetoclax, high‐dose cytarabine and mitoxantrone von Karagiannis, Panagiotis, Alsdorf, Winfried, Tallarek, Ann‐Christin, Blohm, Martin E., Oelrich, Jennyfer, Waizenegger, Jonas S., Wolschke, Christine, Hecher, Kurt, Singer, Dominique, Bokemeyer, Carsten, Fiedler, Walter

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Abstract 3253: Mast cell-derived granzyme b contributes to resistance against anti-angiogenic therapy von Wroblewski, Mark A., Bauer, Raimund, Cubas Córdova, Miguel, Udonta, Florian, Ben Batalla, Isabel, Gensch, Victoria, Sawall, Stefanie, Waizenegger, Jonas S., Pardo Jimeno, Julian, Pantel, Klaus, Bokemeyer, Carsten, Loges, Sonja

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Cyclooxygenase-2 blockade can improve efficacy of VEGF-targeting drugs von Ben-Batalla, Isabel, Cubas-Cordova, Miguel, Udonta, Florian, Wroblewski, Mark, Waizenegger, Jonas S, Janning, Melanie, Sawall, Stefanie, Gensch, Victoria, Zhao, Lin, Martinez-Zubiaurre, Iñigo, Riecken, Kristoffer, Fehse, Boris, Pantel, Klaus, Bokemeyer, Carsten, Loges, Sonja

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AXL Inhibition Represents a Novel Therapeutic Approach in BCR‐ABL Negative Myeloproliferative Neoplasms von Beitzen‐Heineke, Antonia, Berenbrok, Nikolaus, Waizenegger, Jonas, Paesler, Sarina, Gensch, Victoria, Udonta, Florian, Vargas Delgado, Maria Elena, Engelmann, Janik, Hoffmann, Friederike, Schafhausen, Philippe, Amsberg, Gunhild, Riecken, Kristoffer, Beumer, Niklas, Imbusch, Charles D., Lorens, James, Fischer, Thomas, Pantel, Klaus, Bokemeyer, Carsten, Ben‐Batalla, Isabel, Loges, Sonja

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Phase Ib/II Study (NCT02488408 / BGBC003) of Bemcentinib Monotherapy or in Combination with Cytarabine or Decitabine in Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MD... von Loges, Sonja, Heuser, Michael, Chromik, Jolanta, Sutamtewagul, Grerk, Kapp-Schwoerer, Silke, Crugnola, Monica, Di Renzo, Nicola, Lemoli, Roberto Massimo, Mattei, Daniele Giovanni, Ben Batalla, Isabel, Waizenegger, Jonas, Janning, Melanie, Rieckmann, Lisa-Marie, Imbusch, Charles, Beumer, Niklas, Micklam, David, Gorcea-Carson, Claudia, Oliva, Cristina, Fiedler, Walter, Alvarado-Valero, Yesid, McCracken, Nigel, Gjertsen, Bjorn T.

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AML Treatment By the AXL Inhibitor Bemcentinib in Combination with Cytarabine Shows Clinical Efficacy Related to TNFα and Cytotoxic Immune Cells: A Single-Cell Translational Study... von Beumer, Niklas, Waizenegger, Jonas S., Heuser, Michael, Chromik, Jörg, Sutamtewagul, Grerk, Kapp-Schwoerer, Silke, Crugnola, Monica, Di Renzo, Nicola, Lemoli, Roberto M., Mattei, Daniele G., Fiedler, Walter, Alvarado-Valero, Yesid, Micklem, David, Nilsson, Linn H., Madeleine, Noelly, McCracken, Nigel, Oliva, Cristina, Gorcea-Carson, Claudia, Rieckmann, Lisa-Marie, Krause, Jenny, Gensch, Victoria, Ben Batalla, Isabel, Janning, Melanie, Gagliani, Nicola, Brors, Benedikt, Imbusch, Charles D., Gjertsen, Bjorn T., Loges, Sonja

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Mer tyrosine kinase promotes the survival of t(1;19)-positive acute lymphoblastic leukemia (ALL) in the central nervous system (CNS) von Krause, Sarah, Pfeiffer, Christian, Strube, Susanne, Alsadeq, Ameera, Fedders, Henning, Vokuhl, Christian, Loges, Sonja, Waizenegger, Jonas, Ben-Batalla, Isabel, Cario, Gunnar, Möricke, Anja, Stanulla, Martin, Schrappe, Martin, Schewe, Denis M.

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Bemcentinib (Oral AXL Inhibitor) in Combination with Low-Dose Cytarabine Is Well Tolerated and Efficacious in Older Relapsed AML Patients.Updates from the Ongoing Phase II Trial (N... von Loges, Sonja, Sutamtewagul, Grerk, Heuser, Michael, Chromik, Jörg, Kapp-Schwoerer, Silke, Crugnola, Monica, Di Renzo, Nicola, Lemoli, Roberto M., Mattei, Daniele Giovanni, Ben Batalla, Isabel, Hellesøy, Monica, Waizenegger, Jonas, Janning, Melanie, Imbusch, Charles D., Beumer, Niklas, Rayford, Austin, Nautiyal, Jaya, Berkman-Gottlieb, Tzivia, Micklem, David, Gabra, Hani, Gorcea-Carson, Claudia, Lorens, James B., Fiedler, Walter, Alvarado, Yesid, Gjertsen, Bjorn T., Rieckmann, Lisa-Marie

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Blockade of Mer By the Small Molecule Inhibitor R992 Inhibits Multiple Myeloma and Its Associated Bone Disease By Restoring the Perturbed Bone Homeostasis von Engelmann, Janik, Ben Batalla, Isabel, Taipaleenmäki, Hanna, Riecken, Kristoffer, Gensch, Victoria, Paesler, Sarina, Berenbrok, Nikolaus, Vargas, Maria Elena, Waizenegger, Jonas, Fehse, Boris, Pantel, Klaus, Darwish, Ihab S, Bhamidipati, Somasekhar, Masuda, Esteban, Bokemeyer, Carsten, Hesse, Eric, Loges, Sonja

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Abstract 5830: Presence of androgens improves efficacy of PD1 blockade von Vargas-Delgado, María Elena, Meier, Lara, Waizenegger, Jonas, Oberbauer, Julia, Berenbrok, Nikolaus, Engelmann, Janik, Gensch, Victoria, Heilmann, Franziska, Reinert, Jochim, Riecken, Kristoffer, Fehse, Boris, Lotter, Hannelore, Schwinge, Dorothee, Schramm, Christoph, Mittruecker, Hans-Willi, Ben-Batalla, Isabel, Loges, Sonja

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Abstract 1189: MERTK is a target in the microenviroenment of osteolytic bone metastasis von Engelmann, Janik, Zarrer, Jennifer, Riecken, Kristoffer, Waizenegger, Jonas, Vargas-Delgado, Maria Elena, Meier, Lara, Bokemeyer, Carsten, Pantel, Klaus, Alberto, Emily, Ghosh, Sourav, Rothlin, Carla, Hesse, Eric, Taipaleenmäki, Hanna, Ben-Batalla, Isabel, Loges, Sonja

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AXL Inhibition Represents a Novel Therapeutic Approach in BCR-ABL Negative Myeloproliferative Neoplasms von Beitzen-Heineke, Antonia, Berenbrok, Nikolaus, Waizenegger, Jonas, Paesler, Sarina, Gensch, Victoria, Udonta, Florian, Vargas Delgado, Maria Elena, Engelmann, Janik, Hoffmann, Friederike, Schafhausen, Philippe, von Amsberg, Gunhild, Riecken, Kristoffer, Beumer, Niklas, Imbusch, Charles D., Lorens, James, Fischer, Thomas, Pantel, Klaus, Bokemeyer, Carsten, Ben-Batalla, Isabel, Loges, Sonja

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Feasibility studies for a dust observatory between earth and the asteroid belt von Srama, Ralf, Klinkner, Sabine, Fugmann, Martin, Lengowski, Michael, Gläser, Jan, Simolka, Jonas, Sommer, Maximilian, Strack, Heiko, Acker, Denis, Barth, Nadine, Eckstein, Sergej, Filatov, Michael, Gutierrez, Elizabeth, Maydali, Aren, Merz, Florian A., Meyer, Tristan, Pippert, Adrian, Starzmann, Dominik, Stucke, Marvin B., Waizenegger, Kevin

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