Development and application of a fully automatic multi-function cassette module Mortenon M1 for radiopharmaceutical synthesis von Cui, Fang-Bo, Lv, Xuan, Yan, Cheng-Long, Eng, Wai-Si, Yu, Shan-You, Zheng, Qi-Huang

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[¹⁸F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor von Burns, H. Donald, Van Laere, Koen, Sanabria-Bohórquez, Sandra, Hamill, Terence G, Bormans, Guy, Eng, Wai-si, Gibson, Ray, Ryan, Christine, Connolly, Brett, Patel, Shil, Krause, Stephen, Vanko, Amy, Van Hecken, Anne, Dupont, Patrick, De Lepeleire, Inge, Rothenberg, Paul, Stoch, S. Aubrey, Cote, Josee, Hagmann, William K, Jewell, James P, Lin, Linus S, Liu, Ping, Goulet, Mark T, Gottesdiener, Keith, Wagner, John A, de Hoon, Jan, Mortelmans, Luc, Fong, Tung M, Hargreaves, Richard J

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The Acyclic CB1R Inverse Agonist Taranabant Mediates Weight Loss by Increasing Energy Expenditure and Decreasing Caloric Intake von Addy, Carol, Wright, Hamish, Van Laere, Koen, Gantz, Ira, Erondu, Ngozi, Musser, Bret J., Lu, Kaifeng, Yuan, Jinyu, Sanabria-Bohórquez, Sandra M., Stoch, Aubrey, Stevens, Cathy, Fong, Tung M., De Lepeleire, Inge, Cilissen, Caroline, Cote, Josee, Rosko, Kim, Gendrano, Isaias N., Nguyen, Allison Martin, Gumbiner, Barry, Rothenberg, Paul, de Hoon, Jan, Bormans, Guy, Depré, Marleen, Eng, Wai-si, Ravussin, Eric, Klein, Samuel, Blundell, John, Herman, Gary A., Burns, H. Donald, Hargreaves, Richard J., Wagner, John, Gottesdiener, Keith, Amatruda, John M., Heymsfield, Steven B.

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Benzodiazepine Binding Site Occupancy by the Novel GABAA Receptor Subtype-Selective Drug 7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-tri... von Atack, John R, Wong, Dean F, Fryer, Tim D, Ryan, Christine, Sanabria, Sandra, Zhou, Yun, Dannals, Robert F, Eng, Wai-si, Gibson, Raymond E, Burns, H Donald, Vega, Jose M, Vessy, Laura, Scott-Stevens, Paul, Beech, John S, Baron, Jean-Claude, Sohal, Bindi, Schrag, Michael L, Aigbirhio, Franklin I, McKernan, Ruth M, Hargreaves, Richard J

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In Vitro and in Vivo Properties of 3-tert-Butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)-pyrazolo[1,5-d]-[1,2,4]triazine (MRK-016), a GABAA Receptor α5 S... von Atack, John R., Maubach, Karen A., Wafford, Keith A., O’Connor, Desmond, Rodrigues, A. David, Evans, David C., Tattersall, F. David, Chambers, Mark S., MacLeod, Angus M., Eng, Wai-Si, Ryan, Christine, Hostetler, Eric, Sanabria, Sandra M., Gibson, Raymond E., Krause, Stephen, Burns, H. Donald, Hargreaves, Richard J., Agrawal, Nancy G.B., McKernan, Ruth M., Murphy, M. Gail, Gingrich, Kevin, Dawson, Gerard R., Musson, Donald G., Petty, Kevin J.

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Visualization and quantification of neurokinin-1 (NK1) receptors in the human brain von Hietala, Jarmo, Nyman, Mikko J, Eskola, Olli, Laakso, Aki, Grönroos, Tove, Oikonen, Vesa, Bergman, Jörgen, Haaparanta, Merja, Forsback, Sarita, Marjamäki, Päivi, Lehikoinen, Pertti, Goldberg, Michael, Burns, Donald, Hamill, Terence, Eng, Wai-Si, Coimbra, Alexandre, Hargreaves, Richard, Solin, Olof

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Preclinical and clinical pharmacology of TPA023B, a GABAA receptor α2/α3 subtype-selective partial agonist von Atack, JR, Hallett, DJ, Tye, S, Wafford, KA, Ryan, C, Sanabria-Bohórquez, SM, Eng, Wai-si, Gibson, RE, Burns, HD, Dawson, GR, Carling, RW, Street, LJ, Pike, A, De Lepeleire, I, Van Laere, K, Bormans, G, de Hoon, JN, Van Hecken, A, McKernan, RM, Murphy, MG, Hargreaves, RJ

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The plasma–occupancy relationship of the novel GABA A receptor benzodiazepine site ligand, α5IA, is similar in rats and primates von Atack, John R, Eng, Wai‐si, Gibson, Ray E, Ryan, Christine, Francis, Barbara, Sohal, Bindi, Dawson, Gerard R, Hargreaves, Richard J, Burns, H Donald

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The plasma–occupancy relationship of the novel GABAA receptor benzodiazepine site ligand, α5IA, is similar in rats and primates von Atack, John R, Eng, Wai‐si, Gibson, Ray E, Ryan, Christine, Francis, Barbara, Sohal, Bindi, Dawson, Gerard R, Hargreaves, Richard J, Burns, H Donald

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Positron emission tomography neuroreceptor imaging as a tool in drug discovery, research and development von Burns, H Donald, Hamill, Terence G, Eng, Wai-si, Francis, Barbara, Fioravanti, Christine, Gibson, Raymond E

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Development and application of a fully automated multi-function cassette module Mortenon M1 for radiopharmaceutical synthesis von Cui, Fang-Bo, Lv, Xuan, Yan, Cheng-Long, Eng, Wai-Si, Yu, Shan-You, Zheng, Qi-Huang

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The synthesis of several tritiated non-nucleoside, HIV-1 reverse transcriptase inhibitors von Hamill, Terence G., Brenner, Nancy J., Eng, Wai-si, Burns, H. Donald

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Synthesis and bioassay of isoprenoid 3-alkylthio-1,1,1-trifluoro-2-propanones: Potent, selective inhibitors of juvenile hormone esterase von Prestwich, Glenn D., Eng, Wai-Si, Roe, R.Michael, Hammock, Bruce D.

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Syntheses of homologous, tritium-labelled photoaffinity analogs of the natural juvenile hormones JH I, JH II, and JH III von Ujváry, István, Eng, Wai-Si, Prestwich, Glenn D.

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A Cell-Based Radioligand Binding Assay for Farnesyl: Protein Transferase Inhibitors von Lobell, Robert B., Davide, Joseph P., Kohl, Nancy E., Burns, H. Donald, Eng, Wai-Si, Gibson, Raymond E.

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Pharmacological and mechanistic aspects concerning the use of heparin and β-cyclodextrin tetradecasulfate for the treatment of vascular restenosis von Reilly, Christopher F., Fujita, Tsuneo, McFall, Rosemary C., Stabilito, Inez I., Eng, Wai-Si, Johnson, Robert G.

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Neuropeptide Y5 receptor antagonism does not induce clinically meaningful weight loss in overweight and obese adults von Erondu, Ngozi, Gantz, Ira, Musser, Bret, Suryawanshi, Shailaja, Mallick, Madhuja, Addy, Carol, Cote, Josee, Bray, George, Fujioka, Ken, Bays, Harold, Hollander, Priscilla, Sanabria-Bohórquez, Sandra M., Eng, WaiSi, Långström, Bengt, Hargreaves, Richard J., Burns, H. Donald, Kanatani, Akio, Fukami, Takehiro, MacNeil, Douglas J., Gottesdiener, Keith M., Amatruda, John M., Kaufman, Keith D., Heymsfield, Steven B.

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Structure-activity relationships among aromatic analogs of trail-following pheromone of subterranean termites von Prestwich, G.D, Eng, W, Deaton, E, Wichern, D

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A short radiosynthesis of natural juvenile hormone III, methyl [12-3H]-(10R)-10,11-epoxyfarnesoate von Eng, Wai-Si, Prestwich, Glenn D.

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(+)-3-[ 123I]Iodo-MK-801: Synthesis and characterization of binding to the N-methyl-D-aspartate receptor complex von Ransom, Richard W., Eng, Wai-si, Burns, H.Donald, Gibson, Raymond E., Solomon, Howard F.

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