Development of Orally Bioavailable and CNS Penetrant Biphenylaminocyclopropane Carboxamide Bradykinin B1 Receptor Antagonists von Kuduk, Scott D., Di Marco, Christina N., Chang, Ronald K., Wood, Michael R., Schirripa, Kathy M., Kim, June J., Wai, Jenny M. C., DiPardo, Robert M., Murphy, Kathy L., Ransom, Richard W., Harrell, C. Meacham, Reiss, Duane R., Holahan, Marie A., Cook, Jacquelynn, Hess, J. Fred, Sain, Nova, Urban, Mark O., Tang, Cuyue, Prueksaritanont, Thomayant, Pettibone, Douglas J., Bock, Mark G.

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Amidine derived inhibitors of acid-sensing ion channel-3 (ASIC3) von Kuduk, Scott D., Chang, Ronald K., Wai, Jenny M.-C., Di Marco, Christina N., Cofre, Victoria, DiPardo, Robert M., Cook, Sean P., Cato, Matthew J., Jovanovska, Aneta, Urban, Mark O., Leitl, Michael, Spencer, Robert H., Kane, Stefanie A., Hartman, George D., Bilodeau, Mark T.

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2,3-Diaminopyridine Bradykinin B1 Receptor Antagonists von Kuduk, Scott D, Ng, Christina, Feng, Dong-Mei, Wai, Jenny M.-C, Chang, Raymond S. L, Harrell, Charles M, Murphy, Kathy L, Ransom, Richard W, Reiss, Duane, Ivarsson, Magnus, Mason, Glenn, Boyce, Susan, Tang, Cuyue, Prueksaritanont, Thomayant, Freidinger, Roger M, Pettibone, Douglas J, Bock, Mark G

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A priori prediction of activity for HIV-1 protease inhibitors employing energy minimization in the active site von Holloway, M. Katharine, Wai, Jenny M, Halgren, Thomas A, Fitzgerald, Paula M. D, Vacca, Joseph P, Dorsey, Bruce D, Levin, Rhonda B, Thompson, Wayne J, Chen, L. Jenny

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Design and Synthesis of a Pro-Drug of Vinblastine Targeted at Treatment of Prostate Cancer with Enhanced Efficacy and Reduced Systemic Toxicity von Brady, Stephen F, Pawluczyk, Joseph M, Lumma, Patricia K, Feng, Dong-Mei, Wai, Jenny M, Jones, Raymond, DeFeo-Jones, Deborah, Wong, Bradley K, Miller-Stein, Cynthia, Lin, Jiunn H, Oliff, Allen, Freidinger, Roger M, Garsky, Victor M

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Potent HIV protease inhibitors: the development of tetrahydrofuranylglycines as novel P2-ligands and pyrazine amides as P3-ligands von Ghosh, Arun K, Thompson, Wayne J, Holloway, M. Katharine, McKee, Sean P, Duong, Tien T, Lee, Hee Yoon, Munson, Peter M, Smith, Anthony M, Wai, Jenny M, Darke, Paul L, Zugay, Joan A, Emini, Emilio A, Schleif, William A, Huff, Joel R, Anderson, Paul S

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A new class of bradykinin B1 receptor antagonists with high oral bioavailability and minimal PXR activity von FENG, Dong-Mei, DIPARDO, Robert M, PETTIBONE, Douglas J, BOCK, Mark G, KUDUK, Scott D, WAI, Jenny M, CHANG, Ronald K, DI MARCO, Christina N, MURPHY, Kathy L, RANSOM, Richard W, REISS, Duane R, CUYUE TANG, PRUEKSARITANONT, Thomayant

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2,3-diaminopyridine as a platform for designing structurally unique nonpeptide bradykinin B1 receptor antagonists von FENG, Dong-Mei, WAI, Jenny M, CUYUE TANG, PRUEKSARITANONT, Thomayant, FREIDINGER, Roger M, PETTIBONE, Douglas J, BOCK, Mark G, KUDUK, Scott D, NG, Christina, MURPHY, Kathy L, RANSOM, Richard W, REISS, Duane, CHANG, Raymond S. L, HARRELL, Charles M, MACNEIL, Tanya

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A series of potent HIV-1 protease inhibitors containing a hydroxyethyl secondary amine transition state isostere: synthesis, enzyme inhibition, and antiviral activity von Tucker, Thomas J, Lumma, William C, Payne, Linda S, Wai, Jenny M, De Solms, S. Jane, Giuliani, Elizabeth A, Darke, Paul L, Heimbach, Jill C, Zugay, Joan A

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Development of Orally Bioavailable and CNS Penetrant Biphenylaminocyclopropane Carboxamide Bradykinin B 1 Receptor Antagonists von Kuduk, Scott D., Di Marco, Christina N., Chang, Ronald K., Wood, Michael R., Schirripa, Kathy M., Kim, June J., Wai, Jenny M. C., DiPardo, Robert M., Murphy, Kathy L., Ransom, Richard W., Harrell, C. Meacham, Reiss, Duane R., Holahan, Marie A., Cook, Jacquelynn, Hess, J. Fred, Sain, Nova, Urban, Mark O., Tang, Cuyue, Prueksaritanont, Thomayant, Pettibone, Douglas J., Bock, Mark G.

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2,3-Diaminopyridine Bradykinin B 1 Receptor Antagonists von Kuduk, Scott D., Ng, Christina, Feng, Dong-Mei, Wai, Jenny M.-C., Chang, Raymond S. L., Harrell, Charles M., Murphy, Kathy L., Ransom, Richard W., Reiss, Duane, Ivarsson, Magnus, Mason, Glenn, Boyce, Susan, Tang, Cuyue, Prueksaritanont, Thomayant, Freidinger, Roger M., Pettibone, Douglas J., Bock, Mark G.

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A new class of bradykinin B 1 receptor antagonists with high oral bioavailability and minimal PXR activity von Feng, Dong-Mei, DiPardo, Robert M., Wai, Jenny M., Chang, Ronald K., Di Marco, Christina N., Murphy, Kathy L., Ransom, Richard W., Reiss, Duane R., Tang, Cuyue, Prueksaritanont, Thomayant, Pettibone, Douglas J., Bock, Mark G., Kuduk, Scott D.

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2,3-Diaminopyridine as a platform for designing structurally unique nonpeptide bradykinin B 1 receptor antagonists von Feng, Dong-Mei, Wai, Jenny M., Kuduk, Scott D., Ng, Christina, Murphy, Kathy L., Ransom, Richard W., Reiss, Duane, Chang, Raymond S.L., Harrell, Charles M., MacNeil, Tanya, Tang, Cuyue, Prueksaritanont, Thomayant, Freidinger, Roger M., Pettibone, Douglas J., Bock, Mark G.

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A Priori Prediction of Activity for HIV-1 Protease Inhibitors Employing Energy Minimization in the Active Site von Holloway, M. Katharine, Wai, Jenny M, Halgren, Thomas A, Fitzgerald, Paula M. D, Vacca, Joseph P, Dorsey, Bruce D, Levin, Rhonda B, Thompson, Wayne J, Chen, L. Jenny, deSolms, S. Jane, Gaffin, Neil, Ghosh, Arun K, Giuliani, Elizabeth A, Graham, Samuel L, Guare, James P, Hungate, Randall W, Lyle, Terry A, Sanders, William M, Tucker, Thomas J, Wiggins, Mark, Wiscount, Catherine M, Woltersdorf, Otto W, Young, Steven D, Darke, Paul L, Zugay, Joan A

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A new class of bradykinin B sub(1) receptor antagonists with high oral bioavailability and minimal PXR activity von Feng, Dong-Mei, DiPardo, Robert M, Wai, Jenny M, Chang, Ronald K, Di Marco, Christina N, Murphy, Kathy L, Ransom, Richard W, Reiss, Duane R, Tang, Cuyue, Prueksaritanont, Thomayant, Pettibone, Douglas J, Bock, Mark G, Kuduk, Scott D

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Novel conformationally constrained HIV-1 protease inhibitors: rational design, enzyme inhibition, and X-ray structure of an enzyme-inhibtor complex von Kim, B.Moon, Vacca, Joseph P., Fitzgerald, Paula M.D., Darke, Paul L., Holloway, M.Katharine, Guare, James P., Hanifin, Colleen M., Arford-Bickerstaff, Deborah J., Zugay, Joan A., Wai, Jenny M., Anderson, Paul S., Huff, Joel R.

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Spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's Disease von STAUFFER SHAUN R, FAHR BRUCE, BARROW JAMES C, NEILSON LOU ANNE, WAI JENNY M, EGBERTSON MELISSA S, YANG WENJIN, COBURN CRAIG A, LU WANLI

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2-(Bicyclo)alkylamino-derivatives as mediators of chronic pain and inflammation von SU DAI-SHI, WOOD MICHAEL R, WAI JENNY M

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SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE von EGBERTSON, MELISSA, S, FAHR, BRUCE, BARROW, JAMES, C, WAI, JENNY M, YANG, WENJIN, NEILSON, LOU ANNE, COBURN, CRAIG, A, LU, WANLI, STAUFFER, SHAUN, R

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SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE von EGBERTSON, MELISSA, S, FAHR, BRUCE, BARROW, JAMES, C, WAI, JENNY M, YANG, WENJIN, NEILSON, LOU ANNE, COBURN, CRAIG, A, LU, WANLI, STAUFFER, SHAUN, R

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