Glycogen Synthase Kinase-3 Regulates Mitochondrial Outer Membrane Permeabilization and Apoptosis by Destabilization of MCL-1 von Maurer, Ulrich, Charvet, Céline, Wagman, Allan S., Dejardin, Emmanuel, Green, Douglas R.

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Fatty acid synthase - Modern tumor cell biology insights into a classical oncology target von Buckley, Douglas, Duke, Gregory, Heuer, Timothy S, O'Farrell, Marie, Wagman, Allan S, McCulloch, William, Kemble, George

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Synthesis, Binding Mode, and Antihyperglycemic Activity of Potent and Selective (5-Imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine Inhibitors of Glycogen Syntha... von Wagman, Allan S, Boyce, Rustum S, Brown, Sean P, Fang, Eric, Goff, Dane, Jansen, Johanna M, Le, Vincent P, Levine, Barry H, Ng, Simon C, Ni, Zhi-Jie, Nuss, John M, Pfister, Keith B, Ramurthy, Savithri, Renhowe, Paul A, Ring, David B, Shu, Wei, Subramanian, Sharadha, Zhou, Xiaohui A, Shafer, Cynthia M, Harrison, Stephen D, Johnson, Kirk W, Bussiere, Dirksen E

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Selective Glycogen Synthase Kinase 3 Inhibitors Potentiate Insulin Activation of Glucose Transport and Utilization In Vitro and In Vivo von RING, David B, JOHNSON, Kirk W, WAGMAN, Allan S, HAMMOND, Mary-Ellen Wernette, HARRISON, Stephen D, HENRIKSEN, Erik J, NUSS, John M, GOFF, Dane, KINNICK, Tyson R, MA, Sylvia T, REEDER, John W, SAMUELS, Isa, SLABIAK, Trina

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Discovery and optimization of novel pyridines as highly potent and selective glycogen synthase kinase 3 inhibitors von Ramurthy, Savithri, Pfister, Keith B., Boyce, Rustum S., Brown, Sean P., Costales, Abran Q., Desai, Manoj C., Fang, Eric, Levine, Barry H., Ng, Simon C., Nuss, John M., Ring, David B., Shafer, Cynthia M., Shu, Wei, Subramanian, Sharadha, Wagman, Allan S., Wang, Haixia, Bussiere, Dirksen E.

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Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer von Burger, Matthew T, Pecchi, Sabina, Wagman, Allan, Ni, Zhi-Jie, Knapp, Mark, Hendrickson, Thomas, Atallah, Gordana, Pfister, Keith, Zhang, Yanchen, Bartulis, Sarah, Frazier, Kelly, Ng, Simon, Smith, Aaron, Verhagen, Joelle, Haznedar, Joshua, Huh, Kay, Iwanowicz, Ed, Xin, Xiaohua, Menezes, Daniel, Merritt, Hanne, Lee, Isabelle, Wiesmann, Marion, Kaufman, Susan, Crawford, Kenneth, Chin, Michael, Bussiere, Dirksen, Shoemaker, Kevin, Zaror, Isabel, Maira, Sauveur-Michel, Voliva, Charles F

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Synthesis and Microbiological Evaluation of Novel Tetracyclic Fluoroquinolones von Wagman, Allan S., Cirz, Ryan, McEnroe, Glenn, Aggen, James, Linsell, Martin S., Goldblum, Adam A., Lopez, Sara, Gomez, Marcela, Miller, George, Simons, Lloyd J., Belliotti, Thomas R., Harris, Christina R., Poel, Toni‐Jo, Melnick, Michael J., Gaston, Ricky D., Moser, Heinz E.

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Exploring the active site of the Streptococcus pneumoniae topoisomerase IV–DNA cleavage complex with novel 7,8-bridged fluoroquinolones von Laponogov, Ivan, Pan, Xiao-Su, Veselkov, Dennis A., Cirz, Ryan T., Wagman, Allan, Moser, Heinz E., Fisher, L. Mark, Sanderson, Mark R.

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Cover Feature: Synthesis and Microbiological Evaluation of Novel Tetracyclic Fluoroquinolones (ChemMedChem 20/2017) von Wagman, Allan S., Cirz, Ryan, McEnroe, Glenn, Aggen, James, Linsell, Martin S., Goldblum, Adam A., Lopez, Sara, Gomez, Marcela, Miller, George, Simons, Lloyd J., Belliotti, Thomas R., Harris, Christina R., Poel, Toni‐Jo, Melnick, Michael J., Gaston, Ricky D., Moser, Heinz E.

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4-(Aminoalkylamino)-3-benzimidazole-quinolinones as potent CHK-1 inhibitors von Ni, Zhi-Jie, Barsanti, Paul, Brammeier, Nathan, Diebes, Anthony, Poon, Daniel J., Ng, Simon, Pecchi, Sabina, Pfister, Keith, Renhowe, Paul A., Ramurthy, Savithri, Wagman, Allan S., Bussiere, Dirksen E., Le, Vincent, Zhou, Yasheen, Jansen, Johanna M., Ma, Sylvia, Gesner, Thomas G.

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The Total Synthesis of (±)-Ginkgolide B von Crimmins, Michael T, Pace, Jennifer M, Nantermet, Philippe G, Kim-Meade, Agnes S, Thomas, James B, Watterson, Scott H, Wagman, Allan S

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Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors von Burger, Matthew T, Knapp, Mark, Wagman, Allan, Ni, Zhi-Jie, Hendrickson, Thomas, Atallah, Gordana, Zhang, Yanchen, Frazier, Kelly, Verhagen, Joelle, Pfister, Keith, Ng, Simon, Smith, Aaron, Bartulis, Sarah, Merrit, Hanne, Weismann, Marion, Xin, Xiaohua, Haznedar, Joshua, Voliva, Charles F, Iwanowicz, Ed, Pecchi, Sabina

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Total Synthesis of (±)-Ginkgolide B von Crimmins, Michael T, Pace, Jennifer M, Nantermet, Philippe G, Kim-Meade, Agnes S, Thomas, James B, Watterson, Scott H, Wagman, Allan S

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Simple and Efficient Synthesis of 3,4-Dihydro-2-pyridones via Novel Solid-Supported Aza-Annulation von Wagman, Allan S, Wang, Liang, Nuss, John M

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Design, Synthesis, and Evaluation of Phospholipid Analogs as Inhibitors of the Bacterial Phospholipase C from Bacillus cereus von Martin, Stephen F, Wong, Yue-Ling, Wagman, Allan S

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Abstract 4446: Discovery of tumor types highly susceptible to FASN inhibition and biomarker candidates for clinical analysis von Heuer, Timothy S., Ventura, Richard, Mordec, Kasia, Lai, Julie, Waszczuk, Joanna, Hammonds, Glenn, Fridlib, Marina, Johnson, Russell, Hu, Lily, Wagman, Allan, O'Farrell, Marie, Buckley, Douglas, Kemble, George

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Abstract 1815: Efficacy of FASN-selective small molecule inhibitors in preclinical tumor models von Heuer, Timothy S., Ventura, Richard, Waszczuk, Joanna, Mordec, Kasia, Lai, Julie, Johnson, Russell, Hu, Lilly, Cai, Haiying, Wagman, Allan, Buckley, Douglas, Parish, Stanley T., Bruckheimer, Elizabeth, Kemble, George

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Synthesis and Kinetic Evaluation of Inhibitors of the Phosphatidylinositol-Specific Phospholipase C from Bacillus cereus von Martin, Stephen F, Wagman, Allan S

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A general and efficient route to phosphorodithioate analogs of naturally occurring lipids von Martin, Stephen F, Wagman, Allan S

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A general method for the synthesis of 1,1-difluoroalkylphosphonates von Martin, Stephen F., Dean, Daniel W., Wagman, Allan S.

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