Simultaneous JAK/FGFR Inhibition Restores Anti-AR Sensitivity in CRPC

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Lineage plasticity in prostate cancer depends on FGFR and JAK/STAT inflammatory signaling von Chan, J., Zaidi, S., Love, J., Zhao, J., Setty, M., Wadosky, K., Gopalan, A., Choo, Z.N., Persad, S., Chaudhary, O., Xu, T., Masilionis, I., Morris, M., Mazutis, L., Chaligne, R., Chen, Y., Goodrich, D., Karthaus, W., Pe’er, D., Sawyers, C.

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Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity von Pearson, Joel D., Huang, Katherine, Pacal, Marek, McCurdy, Sean R., Lu, Suying, Aubry, Arthur, Yu, Tao, Wadosky, Kristine M., Zhang, Letian, Wang, Tao, Gregorieff, Alex, Ahmad, Mohammad, Dimaras, Helen, Langille, Ellen, Cole, Susan P.C., Monnier, Philippe P., Lok, Benjamin H., Tsao, Ming-Sound, Akeno, Nagako, Schramek, Daniel, Wikenheiser-Brokamp, Kathryn A., Knudsen, Erik S., Witkiewicz, Agnieszka K., Wrana, Jeffrey L., Goodrich, David W., Bremner, Rod

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Notch signaling suppresses neuroendocrine differentiation and alters the immune microenvironment in advanced prostate cancer von Ku, Sheng-Yu, Wang, Yanqing, Garcia, Maria Mica, Yamada, Yasutaka, Mizuno, Kei, Long, Mark D, Rosario, Spencer, Chinnam, Meenalakshmi, Al Assaad, Majd, Puca, Loredana, Kim, Min Jin, Bakht, Martin K, Venkadakrishnan, Varadha Balaji, Robinson, Brian D, Acosta, Andrés M, Wadosky, Kristine M, Mosquera, Juan Miguel, Goodrich, David W, Beltran, Himisha

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