COPD Subtypes Are Differentially Associated With Cardiovascular Events and COPD Exacerbations von Yang, Han-Mo, Ryu, Min Hyung, Carey, Vincent J, Young, Kendra, Kinney, Gregory L, Dransfield, Mark T, Wade, Raymond C, Wells, James M, Budoff, Matthew, Castaldi, Peter J, Hersh, Craig P, Silverman, Edwin K

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Proteomics and machine learning in the prediction and explanation of low pectoralis muscle area von Enzer, Nicholas A., Chiles, Joe, Mason, Stefanie, Shirahata, Toru, Castro, Victor, Regan, Elizabeth, Choi, Bina, Yuan, Nancy F., Diaz, Alejandro A., Washko, George R., McDonald, Merry-Lynn, Estépar, Raúl San José, Ash, Samuel Y.

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Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes von Ruderfer, Douglas M., Boocock, James, Stahl, Eli A., Charney, Alexander W., Ori, Anil P.S., Alliey-Rodriguez, Ney, Anjorin, Adebayo, Badner, Judith A., Band, Gavin, Bruggeman, Richard, Buccola, Nancy G., Bumpstead, Suzannah J., Casas, Juan P., Chan, Raymond C.K., Chen, Ronald Y.L., Collier, David A., Cormican, Paul, Craddock, Nicholas, Crowley, James J., Curtis, David, Dannlowski, Udo, Davidson, Michael, Demontis, Ditte, Dronov, Serge, Elvsashagen, Torbjorn, Etain, Bruno, Fan, Chun Chieh, Forty, Liz, Fraser, Christine, Garnham, Julie, Gill, Michael, Gillman, Matthew, Gratten, Jacob, Gwilliam, Rhian, Hammer, Christian, Hansen, Thomas, Henskens, Frans A., Jamain, Stephane, Jankowski, Janusz, Joa, Inge, Julia, Antonio, Kandaswamy, Radhika, Kavanagh, David, Keller, Matthew C., Khrunin, Andrey, Lee, Phil H., Legge, Sophie E., Lencz, Todd, Levinson, Douglas F., Levy, Shawn E., Li, Tao, Lin, Kuang, Macek, Milan, McCarley, Robert W., McGuffin, Peter, McInnis, Melvin G., Meijer, Carin J., Melegh, Bela, Mesholam-Gately, Raquelle I., Myin-Germeys, Inez, Nicodemus, Kristin K., Nimgaonkar, Vishwajit, Nordin, Annelie, Nöthen, Markus M., Van Os, Jim, Owen, Michael J., Palmer, Colin N.A., Palotie, Aarno, Papadimitriou, George N., Pato, Michele T., Perlis, Roy H., Petryshen, Tracey L., Plomin, Robert, Potash, James B., Powell, John, Ramos-Quiroga, Josep Antoni, Rautanen, Anna, Reichenberg, Abraham, Ribases, Marta, Rice, John P., Richards, Alexander L., Ricketts, Michelle, Sanchez-Mora, Cristina, Sanders, Alan R., Schall, Ulrich, Serretti, Alessandro, Sham, Pak C., Straub, Richard E., Strauss, John S., Szatkiewicz, Jin P., Thompson, Robert C., Thorgeirsson, Thorgeir E., Treutlein, Jens, Vedder, Helmut, Wang, Qiang, Wu, Jing Qin, Sullivan, Patrick F., Wray, Naomi R., Sklar, Pamela, Kendler, Kenneth S.

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Characterization of subsurface polycyclic aromatic hydrocarbons at the Deepwater Horizon site von Diercks, Arne-R., Highsmith, Raymond C., Asper, Vernon L., Joung, DongJoo, Zhou, Zhengzhen, Guo, Laodong, Shiller, Alan M., Joye, Samantha B., Teske, Andreas P., Guinasso, Norman, Wade, Terry L., Lohrenz, Steven E.

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DNA methylation in mice is influenced by genetics as well as sex and life experience von Grimm, Sara A., Shimbo, Takashi, Takaku, Motoki, Thomas, James W., Auerbach, Scott, Bennett, Brian D., Bucher, John R., Burkholder, Adam B., Day, Frank, Du, Ying, Duncan, Christopher G., French, John E., Foley, Julie F., Li, Jianying, Merrick, B. Alex, Tice, Raymond R., Wang, Tianyuan, Xu, Xiaojiang, Bushel, Pierre R., Fargo, David C., Mullikin, James C., Wade, Paul A.

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C‐Terminal Modification and Multimerization Increase the Efficacy of a Proline‐Rich Antimicrobial Peptide von Li, Wenyi, O'Brien‐Simpson, Neil M., Yao, Shenggen, Tailhades, Julien, Reynolds, Eric C., Dawson, Raymond M., Otvos, Laszlo, Hossain, Mohammed Akhter, Separovic, Frances, Wade, John D.

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Dosage compensation and DNA methylation landscape of the X chromosome in mouse liver von Duncan, Christopher G., Grimm, Sara A., Morgan, Daniel L., Bushel, Pierre R., Bennett, Brian D., Roberts, John D., Tyson, Frederick L., Merrick, B. Alex, Wade, Paul A.

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Multidimensional biomarker predicts disease control in response to immunotherapy in recurrent or metastatic head and neck squamous-cell carcinoma von Flanagan, Kevin C., Earls, Jon, Schillebeeckx, Ian, Hiken, Jeffrey, Wellinghoff, Rachel L., LaFranzo, Natalie A., Bradley, Zachary S., Babbitt, Joey, Westra, William H., Hsu, Raymond, Nadauld, Lincoln, Mcleod, Howard, Firth, Sean D., Sharp, Brittany, Fuller, Josh, Vavinskaya, Vera, Sutton, Leisa, Deichaite, Ida, Bailey, Samuel D., Sandulache, Vlad C., Rendo, Matthew J., Macdonald, Orlan K., Welaya, Karim, Wade, James L., Pippas, Andrew W., Slim, Jennifer, Bank, Bruce, Saccaro, Steven J., Sui, Xingwei, Akhtar, Adil, Balaraman, Savitha, Kossman, Steven E., Sonnier, Scott A., Shenkenberg, Todd D., Alexander, Warren L., Price, Katherine A., Bane, Charles L., Ley, Jessica, Messina, David N., Glasscock, Jarret I., Cohen, Ezra E. W., Adkins, Douglas R., Duncavage, Eric J.

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The mutational constraint spectrum quantified from variation in 141,456 humans (vol 581, pg 434, 2020) von Karczewski, Konrad J., Francioli, Laurent C., Tiao, Grace, Cummings, Beryl B., Alfoldi, Jessica, Wang, Qingbo, Collins, Ryan L., Laricchia, Kristen M., Ganna, Andrea, Birnbaum, Daniel P., Gauthier, Laura D., Brand, Harrison, Solomonson, Matthew, Watts, Nicholas A., Rhodes, Daniel, Singer-Berk, Moriel, England, Eleina M., Seaby, Eleanor G., Kosmicki, Jack A., Walters, Raymond K., Tashman, Katherine, Farjoun, Yossi, Banks, Eric, Poterba, Timothy, Wang, Arcturus, Seed, Cotton, Whiffin, Nicola, Chong, Jessica X., Samocha, Kaitlin E., Pierce-Hoffman, Emma, Zappala, Zachary, O'Donnell-Luria, Anne H., Minikel, Eric Vallabh, Weisburd, Ben, Lek, Monkol, Ware, James S., Vittal, Christopher, Armean, Irina M., Bergelson, Louis, Cibulskis, Kristian, Connolly, Kristen M., Covarrubias, Miguel, Donnelly, Stacey, Ferriera, Steven, Gabriel, Stacey, Gentry, Jeff, Gupta, Namrata, Jeandet, Thibault, Kaplan, Diane, Llanwarne, Christopher, Munshi, Ruchi, Novod, Sam, Petrillo, Nikelle, Roazen, David, Ruano-Rubio, Valentin, Saltzman, Andrea, Schleicher, Molly, Soto, Jose, Tibbetts, Kathleen, Tolonen, Charlotte, Wade, Gordon, Talkowski, Michael E., Aggregation, Genome, Neale, Benjamin M., Daly, Mark J., MacArthur, Daniel G.

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The mutational constraint spectrum quantified from variation in 141,456 humans (vol 581, pg 434, 2020) von Gudmundsson, Sanna, Karczewski, Konrad J., Francioli, Laurent C., Tiao, Grace, Cummings, Beryl B., Alfoldi, Jessica, Wang, Qingbo, Collins, Ryan L., Laricchia, Kristen M., Ganna, Andrea, Birnbaum, Daniel P., Gauthier, Laura D., Brand, Harrison, Solomonson, Matthew, Watts, Nicholas A., Rhodes, Daniel, Singer-Berk, Moriel, England, Eleina M., Seaby, Eleanor G., Kosmicki, Jack A., Walters, Raymond K., Tashman, Katherine, Farjoun, Yossi, Banks, Eric, Poterba, Timothy, Wang, Arcturus, Seed, Cotton, Whiffin, Nicola, Chong, Jessica X., Samocha, Kaitlin E., Pierce-Hoffman, Emma, Zappala, Zachary, O'Donnell-Luria, Anne H., Minikel, Eric Vallabh, Weisburd, Ben, Lek, Monkol, Ware, James S., Vittal, Christopher, Armean, Irina M., Bergelson, Louis, Cibulskis, Kristian, Connolly, Kristen M., Covarrubias, Miguel, Donnelly, Stacey, Ferriera, Steven, Gabriel, Stacey, Gentry, Jeff, Gupta, Namrata, Jeandet, Thibault, Kaplan, Diane, Llanwarne, Christopher, Munshi, Ruchi, Novod, Sam, Petrillo, Nikelle, Roazen, David, Ruano-Rubio, Valentin, Saltzman, Andrea, Schleicher, Molly, Soto, Jose, Tibbetts, Kathleen, Tolonen, Charlotte, Wade, Gordon, Talkowski, Michael E., Neale, Benjamin M., Daly, Mark J., MacArthur, Daniel G.

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Willingness to Take, Use of, and Indications for Pre-exposure Prophylaxis Among Men Who Have Sex With Men—20 US Cities, 2014 von Hoots, Brooke E., Finlayson, Teresa, Nerlander, Lina, Paz-Bailey, Gabriela

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Modern External Ring Fixation Versus Internal Fixation for Treatment of Severe Open Tibial Fractures: A Randomized Clinical Trial (FIXIT Study) von Major Extremity Trauma Research Consortium (METRC), Major Extremity Trauma Research Consortium (METRC)

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An Open Drug Discovery Competition: Experimental Validation of Predictive Models in a Series of Novel Antimalarials von Tse, Edwin G, Aithani, Laksh, Anderson, Mark, Cardoso-Silva, Jonathan, Cincilla, Giovanni, Conduit, Gareth J, Galushka, Mykola, Guan, Davy, Hallyburton, Irene, Irwin, Benedict W. J, Kirk, Kiaran, Lehane, Adele M, Lindblom, Julia C. R, Lui, Raymond, Matthews, Slade, McCulloch, James, Motion, Alice, Ng, Ho Leung, Öeren, Mario, Robertson, Murray N, Spadavecchio, Vito, Tatsis, Vasileios A, van Hoorn, Willem P, Wade, Alexander D, Whitehead, Thomas M, Willis, Paul, Todd, Matthew H

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Transport and Management of Patients With Confirmed or Suspected Ebola Virus Disease von Isakov, Alexander, MD, MPH, Miles, Wade, NRP, Gibbs, Shawn, PhD, MBA, Lowe, John, PhD, Jamison, Aaron, NRP, Swansiger, Raymond, PA-C, MPAS

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Phase 2 trial of three schedules of CUE-101 administered before surgery or chemoradiotherapy in HLA-A0201 positive patients with HPV16+ OPSCC von Zaretsky, Jesse Meir, Ley, Jessica C., Oppelt, Peter John, Mullins, Riley, Barrett, Thomas, Jackson, Ryan, Pipkorn, Patrik, Paniello, Randal C, Rich, Jason, Liu, Jingxia, Pennock, Sarah, Cohen, Jared, Thorstad, Wade, Quayle, Steven N, Moniz, Raymond, Goel, Apollina, Levisetti, Matteo, Suri, Anish, Puram, Sidharth, Adkins, Douglas

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Author Correction: The mutational constraint spectrum quantified from variation in 141,456 humans von Karczewski, Konrad J., Francioli, Laurent C., Tiao, Grace, Cummings, Beryl B., Alföldi, Jessica, Wang, Qingbo, Collins, Ryan L., Laricchia, Kristen M., Ganna, Andrea, Birnbaum, Daniel P., Gauthier, Laura D., Brand, Harrison, Solomonson, Matthew, Watts, Nicholas A., Rhodes, Daniel, Singer-Berk, Moriel, England, Eleina M., Seaby, Eleanor G., Kosmicki, Jack A., Walters, Raymond K., Tashman, Katherine, Farjoun, Yossi, Banks, Eric, Poterba, Timothy, Wang, Arcturus, Seed, Cotton, Whiffin, Nicola, Chong, Jessica X., Samocha, Kaitlin E., Pierce-Hoffman, Emma, Zappala, Zachary, O’Donnell-Luria, Anne H., Minikel, Eric Vallabh, Weisburd, Ben, Lek, Monkol, Ware, James S., Vittal, Christopher, Armean, Irina M., Bergelson, Louis, Cibulskis, Kristian, Connolly, Kristen M., Covarrubias, Miguel, Donnelly, Stacey, Ferriera, Steven, Gabriel, Stacey, Gentry, Jeff, Gupta, Namrata, Jeandet, Thibault, Kaplan, Diane, Llanwarne, Christopher, Munshi, Ruchi, Novod, Sam, Petrillo, Nikelle, Roazen, David, Ruano-Rubio, Valentin, Saltzman, Andrea, Schleicher, Molly, Soto, Jose, Tibbetts, Kathleen, Tolonen, Charlotte, Wade, Gordon, Talkowski, Michael E., Neale, Benjamin M., Daly, Mark J., MacArthur, Daniel G.

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A Prospective Randomized Trial to Assess Fixation Strategies for Severe Open Tibia Fractures: Modern Ring External Fixators Versus Internal Fixation (FIXIT Study) von OʼToole, Robert V, Gary, Joshua L, Reider, Lisa, Bosse, Michael J, Gordon, Wade T, Hutson, James, Quinnan, Stephen M, Castillo, Renan C, Scharfstein, Daniel O, MacKenzie, Ellen J

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Addendum: The mutational constraint spectrum quantified from variation in 141,456 humans von Gudmundsson, Sanna, Karczewski, Konrad J., Francioli, Laurent C., Tiao, Grace, Cummings, Beryl B., Alföldi, Jessica, Wang, Qingbo, Collins, Ryan L., Laricchia, Kristen M., Ganna, Andrea, Birnbaum, Daniel P., Gauthier, Laura D., Brand, Harrison, Solomonson, Matthew, Watts, Nicholas A., Rhodes, Daniel, Singer-Berk, Moriel, England, Eleina M., Seaby, Eleanor G., Kosmicki, Jack A., Walters, Raymond K., Tashman, Katherine, Farjoun, Yossi, Banks, Eric, Poterba, Timothy, Wang, Arcturus, Seed, Cotton, Whiffin, Nicola, Chong, Jessica X., Samocha, Kaitlin E., Pierce-Hoffman, Emma, Zappala, Zachary, O’Donnell-Luria, Anne H., Minikel, Eric Vallabh, Weisburd, Ben, Lek, Monkol, Ware, James S., Vittal, Christopher, Armean, Irina M., Bergelson, Louis, Cibulskis, Kristian, Connolly, Kristen M., Covarrubias, Miguel, Donnelly, Stacey, Ferriera, Steven, Gabriel, Stacey, Gentry, Jeff, Gupta, Namrata, Jeandet, Thibault, Kaplan, Diane, Llanwarne, Christopher, Munshi, Ruchi, Novod, Sam, Petrillo, Nikelle, Roazen, David, Ruano-Rubio, Valentin, Saltzman, Andrea, Schleicher, Molly, Soto, Jose, Tibbetts, Kathleen, Tolonen, Charlotte, Wade, Gordon, Talkowski, Michael E., Neale, Benjamin M., Daly, Mark J., MacArthur, Daniel G.

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Abstract 936: Analysis of cell-free DNA from 32,991 advanced cancers reveals novel co-occurring activating RET alterations and oncogenic signaling pathway aberrations von Reckamp, Karen L., Rich, Thereasa A., Chae, Young Kwang, Doebele, Robert C., Iams, Wade T., Oh, Michael, Raymond, Victoria M., Lanman, Richard B., Stinchcombe, Thomas E., Subbiah, Vivek, Trevarthen, David R., Gautschi, Oliver P.

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Parameter estimation for compact binaries with ground-based gravitational-wave observations using the LALInference software library von Veitch, J., Raymond, V., Farr, B., Farr, W., Graff, P., Vitale, S., Aylott, B., Blackburn, K., Christensen, N., Coughlin, M., Del Pozzo, W., Feroz, F., Gair, J., Haster, C.-J., Kalogera, V., Littenberg, T., Mandel, I., O’Shaughnessy, R., Pitkin, M., Rodriguez, C., Röver, C., Sidery, T., Smith, R., Van Der Sluys, M., Vecchio, A., Vousden, W., Wade, L.

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