Large-scale association analyses identify host factors influencing human gut microbiome composition von Kurilshikov, Alexander, Medina-Gomez, Carolina, Bacigalupe, Rodrigo, Radjabzadeh, Djawad, Wang, Jun, Demirkan, Ayse, Le Roy, Caroline I., Raygoza Garay, Juan Antonio, Finnicum, Casey T., Liu, Xingrong, Zhernakova, Daria V., Bonder, Marc Jan, Hansen, Tue H., Frost, Fabian, Rühlemann, Malte C., Turpin, Williams, Moon, Jee-Young, Kim, Han-Na, Lüll, Kreete, Barkan, Elad, Shah, Shiraz A., Fornage, Myriam, Szopinska-Tokov, Joanna, Wallen, Zachary D., Borisevich, Dmitrii, Agreus, Lars, Andreasson, Anna, Bang, Corinna, Bedrani, Larbi, Bell, Jordana T., Bisgaard, Hans, Boehnke, Michael, Boomsma, Dorret I., Burk, Robert D., Claringbould, Annique, Croitoru, Kenneth, Davies, Gareth E., van Duijn, Cornelia M., Duijts, Liesbeth, Falony, Gwen, Fu, Jingyuan, van der Graaf, Adriaan, Hansen, Torben, Homuth, Georg, Hughes, David A., Ijzerman, Richard G., Jackson, Matthew A., Jaddoe, Vincent W. V., Joossens, Marie, Jørgensen, Torben, Keszthelyi, Daniel, Knight, Rob, Laakso, Markku, Laudes, Matthias, Launer, Lenore J., Lieb, Wolfgang, Lusis, Aldons J., Masclee, Ad A. M., Moll, Henriette A., Mujagic, Zlatan, Qibin, Qi, Rothschild, Daphna, Shin, Hocheol, Sørensen, Søren J., Steves, Claire J., Thorsen, Jonathan, Timpson, Nicholas J., Vieira-Silva, Sara, Völker, Uwe, Völzke, Henry, Võsa, Urmo, Wade, Kaitlin H., Walter, Susanna, Watanabe, Kyoko, Weiss, Stefan, Weiss, Frank U., Weissbrod, Omer, Westra, Harm-Jan, Willemsen, Gonneke, Payami, Haydeh, Jonkers, Daisy M. A. E., Arias Vasquez, Alejandro, de Geus, Eco J. C., Stokholm, Jakob, Segal, Eran, Kim, Hyung-Lae, Kaplan, Robert C., Spector, Tim D., Uitterlinden, Andre G., Rivadeneira, Fernando, Franke, Andre, Lerch, Markus M., Franke, Lude, Sanna, Serena, D’Amato, Mauro, Pedersen, Oluf, Paterson, Andrew D., Kraaij, Robert, Raes, Jeroen, Zhernakova, Alexandra

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Response to: “Importance of method assumptions: Response to: “Challenges in undertaking nonlinear Mendelian randomization”” von Wade, KH, Timpson, NJ, Hamilton, FW, Sattar, N, Carslake, D, Davey Smith, G

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Assessing the causal role of adiposity on disordered eating in childhood, adolescence, and adulthood: a Mendelian randomization analysis von Reed, Zoe E, Micali, Nadia, Bulik, Cynthia M, Davey Smith, George, Wade, Kaitlin H

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Variation of all-cause and cause-specific mortality with body mass index in one million Swedish parent-son pairs: An instrumental variable analysis von Wade, Kaitlin H, Carslake, David, Tynelius, Per, Davey Smith, George, Martin, Richard M

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Mendelian randomisation for nutritional psychiatry von Carnegie, Rebecca, Zheng, Jie, Sallis, Hannah M, Jones, Hannah J, Wade, Kaitlin H, Evans, Jonathan, Zammit, Stan, Munafò, Marcus R, Martin, Richard M

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Common variation at 16p11.2 is associated with glycosuria in pregnancy: findings from a genome-wide association study in European women von Lee, MA, McMahon, G, Karhunen, V, Wade, KH, Corbin, LJ, Hughes, DA, Smith, GD, Lawlor, DA, Jarvelin, M-R, Timpson, NJ

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Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes von Bradfield, JP, Kember, RL, Ulrich, A, Balkiyarova, Z, Alyass, A, Aris, IM, Bell, JA, Broadaway, KA, Chen, Z, Chai, J-F, Davies, NM, Fernandez-Orth, D, Bustamante, M, Fore, R, Ganguli, A, Heiskala, A, Hottenga, J-J, Íñiguez, C, Kobes, S, Leinonen, J, Lowry, E, Lyytikainen, L-P, Mahajan, A, Pitkänen, N, Schnurr, TM, Have, CT, Strachan, DP, Vogelezang, S, Wade, KH, Wang, CA, Wong, A, Holm, LA, Chesi, A, Choong, C, Cruz, M, Elliott, P, Franks, S, Frithioff-Bøjsøe, C, Gauderman, WJ, Glessner, JT, Griesman, K, Hanson, RL, Kaakinen, M, Kalkwarf, H, Kelly, A, Kindler, J, Kähönen, M, Lanca, C, Lappe, J, Lee, NR, McCormack, S, Mentch, FD, Mitchell, JA, Mononen, N, Niinikoski, H, Oken, E, Pahkala, K, Sim, X, Teo, Y-Y, Adair, LS, Boomsma, DI, De Geus, E, Eriksson, JG, Felix, JF, Gilliland, FD, Biobank, PM, Hansen, T, Hardy, R, Hivert, M-F, Holm, J-C, Jaddoe, VWV, Järvelin, M-R, Lehtimäki, T, Mackey, DA, Meyre, D, Mohlke, KL, Mykkänen, J, Oberfield, S, Pennell, CE, Perry, JRB, Raitakari, O, Rivadeneira, F, Sebert, S, Shepherd, JA, Standl, M, Timpson, NJ, Torrent, M, Willemsen, G, Hypponen, E, Power, C, Early Growth Genetics Consortium, McCarthy, MI, Freathy, RM, Widén, E, Hakonarson, H, Prokopenko, I, Voight, BF, Zemel, BS, Grant, SFA, Cousminer, DL

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Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes von Bradfield, JP, Kember, RL, Ulrich, A, Balkiyarova, Z, Alyass, A, Aris, IM, Bell, JA, Broadaway, KA, Chen, Z, Chai, JF, Davies, NM, Fernandez-Orth, D, Bustamante, M, Fore, R, Ganguli, A, Heiskala, A, Hottenga, JJ, Íñiguez, C, Kobes, S, Leinonen, J, Lowry, E, Lyytikainen, LP, Mahajan, A, Pitkänen, N, Schnurr, TM, Have, CT, Strachan, DP, Thiering, E, Vogelezang, S, Wade, KH, Wang, CA, Wong, A, Holm, LA, Chesi, A, Choong, C, Cruz, M, Elliott, P, Franks, S, Frithioff-Bøjsøe, C, Gauderman, WJ, Glessner, JT, Gilsanz, V, Griesman, K, Hanson, RL, Kaakinen, M, Kalkwarf, H, Kelly, A, Kindler, J, Kähönen, M, Lanca, C, Lappe, J, Lee, NR, McCormack, S, Mentch, FD, Mitchell, JA, Mononen, N, Niinikoski, H, Oken, E, Pahkala, K, Sim, X, Teo, YY, Baier, LJ, van Beijsterveldt, T, Adair, LS, Boomsma, DI, de Geus, E, Guxens, M, Eriksson, JG, Felix, JF, Gilliland, FD, Biobank, PM, Hansen, T, Hardy, R, Hivert, MF, Holm, JC, Jaddoe, VWV, Järvelin, MR, Lehtimäki, T, Mackey, DA, Meyre, D, Mohlke, KL, Mykkänen, J, Oberfield, S, Pennell, CE, Perry, JRB, Raitakari, O, Rivadeneira, F, Saw, SM, Sebert, S, Shepherd, JA, Standl, M, Sørensen, TIA, Timpson, NJ, Torrent, M, Willemsen, G, Hypponen, E, Power, C, McCarthy, MI, Freathy, RM, Widén, E

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Assessing the causal role of adiposity on disordered eating in childhood, adolescence, and adulthood: a Mendelian randomization analysis von Reed, ZE, Micali, N, Bulik, CM, Smith, GD, Wade, KH

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Associations of Body Mass and Fat Indexes With Cardiometabolic Traits von Bell, JA, Carslake, D, O'Keeffe, LM, Frysz, M, Howe, LD, Hamer, M, Wade, KH, Timpson, NJ, Davey Smith, G

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Determinants of Intima-Media Thickness in the Young: The ALSPAC Study von Chiesa, ST, Charakida, M, Georgiopoulos, G, Dangardt, F, Wade, KH, Rapala, A, Bhowruth, DJ, Nguyen, HC, Muthurangu, V, Shroff, R, Davey Smith, G, Lawlor, DA, Sattar, N, Timpson, NJ, Hughes, AD, Deanfield, JE

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A Region of sigma super(K) Involved in Promoter Activation by GerE in Bacillus subtilis von Wade, KH, Schyns, G, Opdyke, JA, Moran, CP Jr

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Associations of Y chromosomal haplogroups with cardiometabolic risk factors and subclinical vascular measures in males during childhood and adolescence von O'Keeffe, LM, Howe, LD, Fraser, A, Hughes, AD, Wade, KH, Anderson, EL, Lawlor, DA, Erzurumluoglu, AM, Davey-Smith, G, Rodriguez, S, Stergiakouli, E

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Assessing the Causal Role of Body Mass Index on Cardiovascular Health in Young Adults: Mendelian Randomization and Recall-by-Genotype Analyses von Wade, KH, Chiesa, ST, Hughes, AD, Chaturvedi, N, Charakida, M, Rapala, A, Muthurangu, V, Khan, T, Finer, N, Sattar, N, Howe, LD, Fraser, A, Lawlor, DA, Davey Smith, G, Deanfield, JE, Timpson, NJ

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Assessing the causal role of adiposity on early markers of cardiovascular disease: increases in blood pressure, but not metabolic risk factors von Chiesa, STC, Charakida, M, Wade, KH, Hughes, AD, Rapala, A, Khan, T, Fraser, A, Lawlor, DA, Davey Smith, G, Sattar, N, Timpson, NJ, Deanfield, J

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MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations von Hemani, G, Zheng, J, Wade, KH, Laurin, C, Elsworth, B, Burgess, S, Bowden, J, Langdon, R, Tan, V, Yarmolinsky, J, Shihab, HA, Timpson, N, Evans, DM, Relton, C, Martin, RM, Smith, G Davey, Gaunt, TR, Haycock, PC

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A single amino acid substitution in sigma super(E) affects its ability to bind core RNA polymerase von Shuler, M F, Tatti, K M, Wade, KH, Moran, CP Jr

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Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study von Haycock, PC, Burgess, S, Okoli, GN, Bowden, J, Timpson, NJ, Gaunt, TR, Hemani, G, Mangino, M, Ellis, HP, Kurian, KM, Pooley, KA, Chen, WV, Law, MH, Bowdler, LM, Yang, Q, Markus, HS, Hung, RJ, Thompson, DJ, Wolpin, B, Amundadottir, L, Stolzenberg-Solomon, R, Trichopoulou, A, Tumino, R, Svenson, U, van Rij, A, Baas, AF, Bown, MJ, Samani, NJ, Tromp, G, Elmore, JR, Johansson, M, Mckay, J, Gaborieau, V, Brennan, P, Neale, RE, Olson, SH, Risch, HA, Han, J, Abnet, CC, Freedman, ND, Aben, KK, Kiemeney, LA, Turnbull, C, Litchfield, K, Abecasis, GR, Li, Y, Mijatovic, V, Zondervan, KT, Montgomery, GW, van Heel, DA, Sotoodehnia, N, Rosand, J, Brown, WM, Silverman, EK, Hokanson, JE, Morrison, AC, Felix, JF, Petukhova, L, Fan, X, Zhu, C, Langefeld, CD, Wang, F, Lin, X, Rotter, JI, Cotch, MF, Munz, M, Ollila, HM, Hillary, RP, Albagha, O, Zheng, W, Shu, XO, Hüffmeier, U, Kawamura, Y, Otowa, T, Hibberd, ML, Siminovitch, K, Landi, S, Franke, A, Noth, I, Ma, SF, Liu, J, Kim, JW, Delattre, O, Mirabeau, O, Tang, CS, Chang, KP, Martin, NG, Wade, TD, Kubo, M, Nakamura, Y, Kimura, M, Hwang, SJ, Soranzo, N, Manichaikul, AW, Barr, RG, Kahali, B, Wong, TY, Powell, JF, Martin, RM, Davey Smith, G

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A mutation in GerE that affects cotC promoter activation in Bacillus subtilis von Crater, Dinene L., Wade, Kathryn H., Resnekov, Orna, Ichikawa, H.Travis, Kroos, Lee, Brannigan, James A., Moran, Charles P.

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Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes von JP Bradfield, RL Kember, A Ulrich, Z Balkiyarova, A Alyass, IM Aris, JA Bell, KA Broadaway, Z Chen, JF Chai, NM Davies, D Fernandez-Orth, M Bustamante, R Fore, A Ganguli, A Heiskala, JJ Hottenga, C Íñiguez, S Kobes, J Leinonen, E Lowry, LP Lyytikainen, A Mahajan, N Pitkänen, TM Schnurr, CT Have, DP Strachan, E Thiering, S Vogelezang, KH Wade, CA Wang, A Wong, LA Holm, A Chesi, C Choong, M Cruz, P Elliott, S Franks, C Frithioff-Bøjsøe, WJ Gauderman, JT Glessner, V Gilsanz, K Griesman, RL Hanson, M Kaakinen, H Kalkwarf, A Kelly, J Kindler, M Kähönen, C Lanca, J Lappe, NR Lee, S McCormack, FD Mentch, JA Mitchell, N Mononen, H Niinikoski, E Oken, K Pahkala, X Sim, YY Teo, LJ Baier, T van Beijsterveldt, LS Adair, DI Boomsma, E de Geus, M Guxens, JG Eriksson, JF Felix, FD Gilliland, PM Biobank, T Hansen, Rebecca Hardy, MF Hivert, JC Holm, VWV Jaddoe, MR Järvelin, T Lehtimäki, DA Mackey, D Meyre, KL Mohlke, J Mykkänen, S Oberfield, CE Pennell, JRB Perry, O Raitakari, F Rivadeneira, SM Saw, S Sebert, JA Shepherd, M Standl, TIA Sørensen, NJ Timpson, M Torrent, G Willemsen, E Hypponen, C Power, MI McCarthy, RM Freathy, E Widén

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