Systematic analysis of ribophagy in human cells reveals bystander flux during selective autophagy von An, Heeseon, Harper, J. Wade

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Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval von King, Emily A, Davis, J Wade, Degner, Jacob F

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Building and decoding ubiquitin chains for mitophagy von Harper, J. Wade, Ordureau, Alban, Heo, Jin-Mi

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The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy von Heo, Jin-Mi, Ordureau, Alban, Paulo, Joao A., Rinehart, Jesse, Harper, J. Wade

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Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome von Kim, Woong, Bennett, Eric J., Huttlin, Edward L., Guo, Ailan, Li, Jing, Possemato, Anthony, Sowa, Mathew E., Rad, Ramin, Rush, John, Comb, Michael J., Harper, J. Wade, Gygi, Steven P.

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Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation von Münch, Christian, Harper, J. Wade

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SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway von Gu, Xin, Orozco, Jose M., Saxton, Robert A., Condon, Kendall J., Liu, Grace Y., Krawczyk, Patrycja A., Scaria, Sonia M., Harper, J. Wade, Gygi, Steven P., Sabatini, David M.

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Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways von Schulman, Brenda A., Wade Harper, J.

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The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase von McKenna, Michael J, Sim, Sue Im, Ordureau, Alban, Wei, Lianjie, Harper, J Wade, Shao, Sichen, Park, Eunyong

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Ribosome Abundance Control Via the Ubiquitin–Proteasome System and Autophagy von An, Heeseon, Harper, J. Wade

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Defining human ERAD networks through an integrative mapping strategy von Christianson, John C., Olzmann, James A., Shaler, Thomas A., Sowa, Mathew E., Bennett, Eric J., Richter, Caleb M., Tyler, Ryan E., Greenblatt, Ethan J., Wade Harper, J., Kopito, Ron R.

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Architecture of the human interactome defines protein communities and disease networks von Huttlin, Edward L., Bruckner, Raphael J., Paulo, Joao A., Cannon, Joe R., Ting, Lily, Baltier, Kurt, Colby, Greg, Gebreab, Fana, Gygi, Melanie P., Parzen, Hannah, Szpyt, John, Tam, Stanley, Zarraga, Gabriela, Pontano-Vaites, Laura, Swarup, Sharan, White, Anne E., Schweppe, Devin K., Rad, Ramin, Erickson, Brian K., Obar, Robert A., Guruharsha, K. G., Li, Kejie, Artavanis-Tsakonas, Spyros, Gygi, Steven P., Harper, J. Wade

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Cullin-RING Ubiquitin Ligase Regulatory Circuits: A Quarter Century Beyond the F-Box Hypothesis von Harper, J. Wade, Schulman, Brenda A

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Quantifying Ubiquitin Signaling von Ordureau, Alban, Münch, Christian, Harper, J. Wade

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Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy von Mancias, Joseph D., Wang, Xiaoxu, Gygi, Steven P., Harper, J. Wade, Kimmelman, Alec C.

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Proteome complexity and the forces that drive proteome imbalance von Harper, J. Wade, Bennett, Eric J.

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A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation von Timms, Richard T., Zhang, Zhiqian, Rhee, David Y., Harper, J. Wade, Koren, Itay, Elledge, Stephen J.

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Endosome-ER Contacts Control Actin Nucleation and Retromer Function through VAP-Dependent Regulation of PI4P von Dong, Rui, Saheki, Yasunori, Swarup, Sharan, Lucast, Louise, Harper, J. Wade, De Camilli, Pietro

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Structure of a RING E3 Trapped in Action Reveals Ligation Mechanism for the Ubiquitin-like Protein NEDD8 von Scott, Daniel C., Sviderskiy, Vladislav O., Monda, Julie K., Lydeard, John R., Cho, Shein Ei, Harper, J. Wade, Schulman, Brenda A.

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TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress von An, Heeseon, Ordureau, Alban, Paulo, Joao A., Shoemaker, Christopher J., Denic, Vladimir, Harper, J. Wade

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