High-Pressure Entry into Platencin von Waalboer, Dennis C.J, Schaapman, Mark C, van Delft, Floris L, Rutjes, Floris P.J.T

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A Novel Platinum(II)-Based Bifunctional ADC Linker Benchmarked Using 89Zr-Desferal and Auristatin F-Conjugated Trastuzumab von Sijbrandi, Niels J, Merkul, Eugen, Muns, Joey A, Waalboer, Dennis C J, Adamzek, Kevin, Bolijn, Marije, Montserrat, Veronica, Somsen, Govert W, Haselberg, Rob, Steverink, Paul J G M, Houthoff, Hendrik-Jan, van Dongen, Guus A M S

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Platinum(II) as Bifunctional Linker in Antibody-Drug Conjugate Formation: Coupling of a 4-Nitrobenzo-2-oxa-1,3-diazole Fluorophore to Trastuzumab as a Model von Waalboer, Dennis C. J., Muns, Joey A., Sijbrandi, Niels J., Schasfoort, Richard B. M., Haselberg, Rob, Somsen, Govert W., Houthoff, Hendrik-Jan, van Dongen, Guus A. M. S.

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Discovery of Potent, Orally Bioavailable, Small-Molecule Inhibitors of WNT Signaling from a Cell-Based Pathway Screen von Mallinger, Aurélie, Crumpler, Simon, Pichowicz, Mark, Waalboer, Dennis, Stubbs, Mark, Adeniji-Popoola, Olajumoke, Wood, Bozena, Smith, Elizabeth, Thai, Ching, Henley, Alan T, Georgi, Katrin, Court, William, Hobbs, Steve, Box, Gary, Ortiz-Ruiz, Maria-Jesus, Valenti, Melanie, De Haven Brandon, Alexis, TePoele, Robert, Leuthner, Birgitta, Workman, Paul, Aherne, Wynne, Poeschke, Oliver, Dale, Trevor, Wienke, Dirk, Esdar, Christina, Rohdich, Felix, Raynaud, Florence, Clarke, Paul A, Eccles, Suzanne A, Stieber, Frank, Schiemann, Kai, Blagg, Julian

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Total Synthesis and Absolute Stereochemistry of Integric Acid von Waalboer, Dennis C. J, van Kalkeren, Henri A, Schaapman, Mark C, van Delft, Floris L, Rutjes, Floris P. J. T

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Total Synthesis and Antibiotic Activity of Dehydrohomoplatencin von Waalboer, Dennis C. J., Leenders, Stefan H. A. M., Schülin-Casonato, Tanja, van Delft, Floris L., Rutjes, Floris P. J. T.

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A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease von Dale, Trevor, Clarke, Paul A, Esdar, Christina, Waalboer, Dennis, Adeniji-Popoola, Olajumoke, Ortiz-Ruiz, Maria-Jesus, Mallinger, Aurélie, Samant, Rahul S, Czodrowski, Paul, Musil, Djordje, Schwarz, Daniel, Schneider, Klaus, Stubbs, Mark, Ewan, Ken, Fraser, Elizabeth, TePoele, Robert, Court, Will, Box, Gary, Valenti, Melanie, de Haven Brandon, Alexis, Gowan, Sharon, Rohdich, Felix, Raynaud, Florence, Schneider, Richard, Poeschke, Oliver, Blaukat, Andree, Workman, Paul, Schiemann, Kai, Eccles, Suzanne A, Wienke, Dirk, Blagg, Julian

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1160 Phosphonate-antibody-drug conjugates: a novel immunostimulatory class of ADCs driving inside-out activation of Vγ9Vδ2 T cells leading to selective tumor cell killing von Helden, Mary J van, Elgersma, Ronald C, Kuppeveld, Daphne WJ van, Waalboer, Dennis, Damming, Désirée, Santegoeds-Lenssen, Ellen WH, Leenders, Inge, Laat-Arts, Karin de, Driessen-Engels, Lilian, Paradé, Marc CBC, Winkel, Menno, Scholzen, Anja, Wijk, Daniëlle EJW van, Dobbelsteen, Diels van den, Filiciotto, Genny, Assink, Laura, Rouwette, Myrthe, Spantidea, Panagiota I, Arends, Roel J, Berg, Timo K van den, Kappers, Wendela A, Verheijden, Gijs, Dokter, Wim HA, van der Lee, Miranda MC

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A Ring-Closing Metathesis Approach to Cyclic α,β-Dehydroamino Acids von Hekking, Koen F. W., Waalboer, Dennis C. J., Moelands, Marcel A. H., van Delft, Floris L., Rutjes, Floris P. J. T.

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An Improved Ring-Closing Metathesis Approach to Fluorinated and Trifluoromethylated Nitrogen Heterocycles von De Matteis, Valeria, Dufay, Olivier, Waalboer, Dennis C. J., van Delft, Floris L., Tiebes, Jörg, Rutjes, Floris P. J. T.

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A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease von Dale, Trevor, Clarke, Paul A, Esdar, Christina, Waalboer, Dennis, Adeniji-Popoola, Olajumoke, Ortiz-Ruiz, Maria-Jesus, Mallinger, Aurélie, Samant, Rahul S, Czodrowski, Paul, Musil, Djordje, Schwarz, Daniel, Schneider, Klaus, Stubbs, Mark, Ewan, Ken, Fraser, Elizabeth, TePoele, Robert, Court, Will, Box, Gary, Valenti, Melanie, de Haven Brandon, Alexis, Gowan, Sharon, Rohdich, Felix, Raynaud, Florence, Schneider, Richard, Poeschke, Oliver, Blaukat, Andree, Workman, Paul, Schiemann, Kai, Eccles, Suzanne A, Wienke, Dirk, Blagg, Julian

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Abstract PR02: Identification of a potent and selective chemical probe for exploring the role of CDK8/19 in cancer biology von Clarke, Paul A., Dale, Trevor, Esdar, Christina, Waalboer, Dennis, Adeniji-Popoola, Olajumoke, Ortiz-Ruiz, Maria-Jesus, Mallinger, Aurelie, Ewan, Ken, te Poele, Robert, Gowan, Sharon, Workman, Paul, Schiemann, Kai, Eccles, Suzanne A., Wienke, Dirk, Blagg, Julian

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Abstract 3025: Discovery of preclinical development candidate inhibitors of the mediator complex-associated kinases CDK8 and CDK19 and evaluation of their therapeutic potential von Clarke, Paul, Esdar, Christina, Mallinger, Aurelie, Schiemann, Kai, Waalboer, Dennis, Crumpler, Simon, Rink, Christian, Stieber, Frank, Calderini, Michel, Adeniji-Popoola, Olajumoke, Ortiz-Ruiz, Maria-Jesus, Samant, Rahul S., Czodrowski, Paul, Musil, Djordje, Schwarz, Daniel, Schneider, Klaus, Busch, Michael, Stubbs, Mark, Burke, Rosemary, TePoele, Robert, Gowan, Sharon, Rohdich, Felix, Raynaud, Florence, Schneider, Richard, Poeschke, Oliver, Blaukat, Andree, Urbahns, Klaus, Workman, Paul, Kaufmann, Wolfgang, Simon, Stephanie, Eccles, Suzanne A., Dale, Trevor, Wienke, Dirk, Blagg, Julian

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NOVEL LINKER DRUGS COMPRISING PHOSPHOANTIGENS, NOVEL CONJUGATES AND THEIR USE IN THERAPY von WAALBOER, Dennis, ELGERSMA, Ronald

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Synthesis and Biological Activity of Novel von C.J. Waalboer, Dennis, P.J.T. Rutjes, Floris

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Synthesis and Biological Activity of Novel Platencin Derivatives von Dennis C. J.Waalboer, Floris P. J.T. Rutjes

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CONJUGATES COMPRISING PHOSPHOANTIGENS AND THEIR USE IN THERAPY von WAALBOER, Dennis Christian Johannes, ELGERSMA, Ronald Christiaan

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CONJUGATES COMPRISING PHOSPHOANTIGENS AND THEIR USE IN THERAPY von WAALBOER, Dennis Christian Johannes, ELGERSMA, Ronald Christiaan

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CONJUGATES COMPRISING PHOSPHOANTIGENS AND THEIR USE IN THERAPY von WAALBOER, Dennis Christian Johannes, ELGERSMA, Ronald Christiaan

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CONJUGATES COMPRISING PHOSPHOANTIGENS AND THEIR USE IN THERAPY von ELGERSMA, RONALD CHRISTIAAN, WAALBOER, DENNIS CHRISTIAN JOHANNES

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