Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics von Paik, David T., Chandy, Mark, Wu, Joseph C.

Volltext

Stem Cell Imaging: From Bench to Bedside von Nguyen, Patricia K., Riegler, Johannes, Wu, Joseph C.

Volltext

Production of De Novo Cardiomyocytes: Human Pluripotent Stem Cell Differentiation and Direct Reprogramming von Burridge, Paul W., Keller, Gordon, Gold, Joseph D., Wu, Joseph C.

Volltext

Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis von Wirka, Robert C., Wagh, Dhananjay, Paik, David T., Pjanic, Milos, Nguyen, Trieu, Miller, Clint L., Kundu, Ramen, Nagao, Manabu, Coller, John, Koyano, Tiffany K., Fong, Robyn, Woo, Y. Joseph, Liu, Boxiang, Montgomery, Stephen B., Wu, Joseph C., Zhu, Kuixi, Chang, Rui, Alamprese, Melissa, Tallquist, Michelle D., Kim, Juyong B., Quertermous, Thomas

Volltext

Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies von Lee, Andrew S, Tang, Chad, Rao, Mahendra S, Weissman, Irving L, Wu, Joseph C

Volltext

Strategies for Improving the Maturity of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes von Tu, Chengyi, Chao, Benjamin S, Wu, Joseph C

Volltext

Shifting machine learning for healthcare from development to deployment and from models to data von Zhang, Angela, Xing, Lei, Zou, James, Wu, Joseph C.

Volltext

Chemically defined generation of human cardiomyocytes von Burridge, Paul W, Matsa, Elena, Shukla, Praveen, Lin, Ziliang C, Churko, Jared M, Ebert, Antje D, Lan, Feng, Diecke, Sebastian, Huber, Bruno, Mordwinkin, Nicholas M, Plews, Jordan R, Abilez, Oscar J, Cui, Bianxiao, Gold, Joseph D, Wu, Joseph C

Volltext

A computational model of induced pluripotent stem‐cell derived cardiomyocytes incorporating experimental variability from multiple data sources von Kernik, Divya C., Morotti, Stefano, Wu, HaoDi, Garg, Priyanka, Duff, Henry J., Kurokawa, Junko, Jalife, José, Wu, Joseph C., Grandi, Eleonora, Clancy, Colleen E.

Volltext

Use of Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes in Preclinical Cancer Drug Cardiotoxicity Testing: A Scientific Statement From the American Heart Association von Gintant, Gary, Burridge, Paul, Gepstein, Lior, Harding, Sian, Herron, Todd, Hong, Charles, Jalife, José, Wu, Joseph C

Volltext

FDA Modernization Act 2.0: transitioning beyond animal models with human cells, organoids, and AI/ML-based approaches von Zushin, Peter-James H, Mukherjee, Souhrid, Wu, Joseph C

Volltext

Personalized medicine in cardio-oncology: the role of induced pluripotent stem cell von Sayed, Nazish, Ameen, Mohamed, Wu, Joseph C

Volltext

Global Epigenomic Reconfiguration During Mammalian Brain Development von Lister, Ryan, Mukamel, Eran A., Nery, Joseph R., Urich, Mark, Puddifoot, Clare A., Johnson, Nicholas D., Lucero, Jacinta, Huang, Yun, Dwork, Andrew J., Schultz, Matthew D., Yu, Miao, Tonti-Filippini, Julian, Heyn, Holger, Hu, Shijun, Wu, Joseph C., Rao, Anjana, Esteller, Manel, He, Chuan, Haghighi, Fatemeh G., Sejnowski, Terrence J., Behrens, M. Margarita, Ecker, Joseph R.

Volltext

Use of human induced pluripotent stem cell–derived cardiomyocytes to assess drug cardiotoxicity von Sharma, Arun, McKeithan, Wesley L., Serrano, Ricardo, Kitani, Tomoya, Burridge, Paul W., del Álamo, Juan C., Mercola, Mark, Wu, Joseph C.

Volltext

Human Induced Pluripotent Stem Cells as a Platform for Personalized and Precision Cardiovascular Medicine von Matsa, Elena, Ahrens, John H, Wu, Joseph C

Volltext

Genome Editing of Isogenic Human Induced Pluripotent Stem Cells Recapitulates Long QT Phenotype for Drug Testing von Wang, Yongming, PhD, Liang, Ping, MD, PhD, Lan, Feng, PhD, Wu, Haodi, PhD, Lisowski, Leszek, PhD, Gu, Mingxia, MD, PhD, Hu, Shijun, PhD, Kay, Mark A., MD, PhD, Urnov, Fyodor D., PhD, Shinnawi, Rami, PhD, Gold, Joseph D., PhD, Gepstein, Lior, MD, PhD, Wu, Joseph C., MD, PhD

Volltext

Elucidating effects of environmental exposure using human‐induced pluripotent stem cell disease modeling von Chandy, Mark, Obal, Detlef, Wu, Joseph C

Volltext

Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy von Lee, Jaecheol, Termglinchan, Vittavat, Diecke, Sebastian, Itzhaki, Ilanit, Lam, Chi Keung, Garg, Priyanka, Lau, Edward, Greenhaw, Matthew, Seeger, Timon, Wu, Haodi, Zhang, Joe Z., Chen, Xingqi, Gil, Isaac Perea, Ameen, Mohamed, Sallam, Karim, Rhee, June-Wha, Churko, Jared M., Chaudhary, Rinkal, Chour, Tony, Wang, Paul J., Snyder, Michael P., Chang, Howard Y., Karakikes, Ioannis, Wu, Joseph C.

Volltext

Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis von Churko, Jared M., Garg, Priyanka, Treutlein, Barbara, Venkatasubramanian, Meenakshi, Wu, Haodi, Lee, Jaecheol, Wessells, Quinton N., Chen, Shih-Yu, Chen, Wen-Yi, Chetal, Kashish, Mantalas, Gary, Neff, Norma, Jabart, Eric, Sharma, Arun, Nolan, Garry P., Salomonis, Nathan, Wu, Joseph C.

Volltext

Large-Scale Single-Cell RNA-Seq Reveals Molecular Signatures of Heterogeneous Populations of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells von Paik, David T, Tian, Lei, Lee, Jaecheol, Sayed, Nazish, Chen, Ian Y, Rhee, Siyeon, Rhee, June-Wha, Kim, Youngkyun, Wirka, Robert C, Buikema, Jan W, Wu, Sean M, Red-Horse, Kristy, Quertermous, Thomas, Wu, Joseph C

Volltext