A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy von Li, John Y., Perry, Samuel R., Muniz-Medina, Vanessa, Wang, Xinzhong, Wetzel, Leslie K., Rebelatto, Marlon C., Hinrichs, Mary Jane Masson, Bezabeh, Binyam Z., Fleming, Ryan L., Dimasi, Nazzareno, Feng, Hui, Toader, Dorin, Yuan, Andy Q., Xu, Lan, Lin, Jia, Gao, Changshou, Wu, Herren, Dixit, Rakesh, Osbourn, Jane K., Coats, Steven R.

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Properties of Human IgG1s Engineered for Enhanced Binding to the Neonatal Fc Receptor (FcRn) von Dall'Acqua, William F., Kiener, Peter A., Wu, Herren

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Characterization of Disulfide Bond Rebridged Fab–Drug Conjugates Prepared Using a Dual Maleimide Pyrrolobenzodiazepine Cytotoxic Payload von Ruddle, Ben T., Fleming, Ryan, Wu, Herren, Gao, Changshou, Dimasi, Nazzareno

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A Hoechst Reporter Enables Visualization of Drug Engagement In Vitro and In Vivo: Toward Safe and Effective Nanodrug Delivery von Miyazaki, Takuya, Chen, Shaoyi, Florinas, Stelios, Igarashi, Kazunori, Matsumoto, Yu, Yamasoba, Tatsuya, Xu, Ze-Qi, Wu, Herren, Gao, Changshou, Kataoka, Kazunori, Christie, R. James, Cabral, Horacio

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DLL4-Notch Signaling Mediates Tumor Resistance to Anti-VEGF Therapy In Vivo von LI, Ji-Liang, SAINSON, Richard C. A, WU, Herren, CHOWDHURY, Partha S, RUSSELL, Angela J, MONTGOMERY, Craig P, POULSOM, Richard, HARRIS, Adrian L, EIN OON, Chern, TURLEY, Helen, LEEK, Russell, SHELDON, Helen, BRIDGES, Esther, SHI, Wen, SNELL, Cameron, BOWDEN, Emma T

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A Diene‐Containing Noncanonical Amino Acid Enables Dual Functionality in Proteins: Rapid Diels–Alder Reaction with Maleimide or Proximity‐Based Dimerization von St. Amant, Andre H., Huang, Fengying, Lin, Jia, Rickert, Keith, Oganesyan, Vaheh, Lemen, Daniel, Mao, Shenlan, Harper, Jay, Marelli, Marcello, Wu, Herren, Gao, Changshou, Read de Alaniz, Javier, Christie, R. James

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Regulation of antibody-mediated complement-dependent cytotoxicity by modulating the intrinsic affinity and binding valency of IgG for target antigen von Wang, Bo, Yang, Chunning, Jin, Xiaofang, Du, Qun, Wu, Herren, Dall'Acqua, William, Mazor, Yariv

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Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE von Coyle, Anthony J, Tian, Jane, Avalos, Ana Maria, Mao, Su-Yau, Chen, Bo, Senthil, Kannaki, Wu, Herren, Parroche, Peggy, Drabic, Stacey, Golenbock, Douglas, Sirois, Cherilyn, Hua, Jing, An, Ling Ling, Audoly, Laurent, La Rosa, Greg, Bierhaus, Angelika, Naworth, Peter, Marshak-Rothstein, Ann, Crow, Mary K, Fitzgerald, Katherine A, Latz, Eicke, Kiener, Peter A

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MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function von Kolbeck, Roland, PhD, Kozhich, Alexander, PhD, Koike, Masamichi, PhD, Peng, Li, PhD, Andersson, Cecilia K., PhD, Damschroder, Melissa M., BA, Reed, Jennifer L., PhD, Woods, Robert, MS, Dall'Acqua, William W., PhD, Stephens, Geoffrey L., PhD, Erjefalt, Jonas S., PhD, Bjermer, Leif, MD, Humbles, Alison A., PhD, Gossage, David, MD, Wu, Herren, PhD, Kiener, Peter A., PhD, Spitalny, George L., PhD, Mackay, Charles R., PhD, Molfino, Nestor A., MD, Coyle, Anthony J., PhD

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Structural characterization of a human Fc fragment engineered for lack of effector functions von Oganesyan, Vaheh, Gao, Changshou, Shirinian, Lena, Wu, Herren, Dall'Acqua, William F.

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Improving target cell specificity using a novel monovalent bispecific IgG design von Mazor, Yariv, Oganesyan, Vaheh, Yang, Chunning, Hansen, Anna, Wang, Jihong, Liu, Hongji, Sachsenmeier, Kris, Carlson, Marcia, Gadre, Dhanesh V, Borrok, Martin Jack, Yu, Xiang-Qing, Dall'Acqua, William, Wu, Herren, Chowdhury, Partha Sarathi

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Development of a fluorescent reporter system for monitoring ER stress in Chinese hamster ovary cells and its application for therapeutic protein production von Roy, Gargi, Zhang, Shu, Li, Lina, Higham, Eileen, Wu, Herren, Marelli, Marcello, Bowen, Michael A

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A Therapeutic Uricase with Reduced Immunogenicity Risk and Improved Development Properties von Nyborg, Andrew C, Ward, Chris, Zacco, Anna, Chacko, Benoy, Grinberg, Luba, Geoghegan, James C, Bean, Ryan, Wendeler, Michaela, Bartnik, Frank, O'Connor, Ellen, Gruia, Flaviu, Iyer, Vidyashankara, Feng, Hui, Roy, Varnika, Berge, Mark, Miner, Jeffrey N, Wilson, David M, Zhou, Dongmei, Nicholson, Simone, Wilker, Clynn, Wu, Chi Y, Wilson, Susan, Jermutus, Lutz, Wu, Herren, Owen, David A, Osbourn, Jane, Coats, Steven, Baca, Manuel

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Respiratory Syncytial Virus-Neutralizing Monoclonal Antibodies Motavizumab and Palivizumab Inhibit Fusion von Huang, Kelly, Incognito, Len, Cheng, Xing, Ulbrandt, Nancy D, Wu, Herren

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Development of Motavizumab, an Ultra-potent Antibody for the Prevention of Respiratory Syncytial Virus Infection in the Upper and Lower Respiratory Tract von Wu, Herren, Pfarr, David S., Johnson, Syd, Brewah, Yambasu A., Woods, Robert M., Patel, Nita K., White, Wendy I., Young, James F., Kiener, Peter A.

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A Nanoparticle Platform To Evaluate Bioconjugation and Receptor-Mediated Cell Uptake Using Cross-Linked Polyion Complex Micelles Bearing Antibody Fragments von Florinas, Stelios, Liu, Marc, Fleming, Ryan, Van Vlerken-Ysla, Lilian, Ayriss, Joanne, Gilbreth, Ryan, Dimasi, Nazzareno, Gao, Changshou, Wu, Herren, Xu, Ze-Qi, Chen, Shaoyi, Dirisala, Anjaneyulu, Kataoka, Kazunori, Cabral, Horacio, Christie, R. James

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Enhancement of Immune Effector Functions by Modulating IgG's Intrinsic Affinity for Target Antigen von Mazor, Yariv, Yang, Chunning, Borrok, M Jack, Ayriss, Joanne, Aherne, Karen, Wu, Herren, Dall'Acqua, William F

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Recombinant human B cell repertoires enable screening for rare, specific, and natively paired antibodies von Rajan, Saravanan, Kierny, Michael R., Mercer, Andrew, Wu, Jincheng, Tovchigrechko, Andrey, Wu, Herren, Dall′Acqua, William F., Xiao, Xiaodong, Chowdhury, Partha S.

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Correction: Upregulation of annexin A1 protein expression in the intratumoral vasculature of human non-small-cell lung carcinoma and rodent tumor models von Allen, Kevin L, Cann, Jennifer, Zhao, Weiguang, Peterson, Norman, Lazzaro, Michelle, Zhong, Haihong, Wu, Herren, Dall'Acqua, William F, Borrok, M Jack, Damschroder, Melissa M, Tsui, Ping, Li, Qing

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Upregulation of annexin A1 protein expression in the intratumoral vasculature of human non-small-cell lung carcinoma and rodent tumor models von Allen, Kevin L, Cann, Jennifer, Zhao, Weiguang, Peterson, Norman, Lazzaro, Michelle, Zhong, Haihong, Wu, Herren, Dall'Acqua, William F, Borrok, M Jack, Damschroder, Melissa M, Tsui, Ping, Li, Qing

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