Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome von Gray, Elizabeth E, Treuting, Piper M, Woodward, Joshua J, Stetson, Daniel B

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SLC19A1 transports immunoreactive cyclic dinucleotides von Luteijn, Rutger D., Zaver, Shivam A., Gowen, Benjamin G., Wyman, Stacia K., Garelis, Nick E., Onia, Liberty, McWhirter, Sarah M., Katibah, George E., Corn, Jacob E., Woodward, Joshua J., Raulet, David H.

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Cutting edge: Antimalarial drugs inhibit IFN-β production through blockade of cyclic GMP-AMP synthase-DNA interaction von An, Jie, Woodward, Joshua J, Sasaki, Tomikazu, Minie, Mark, Elkon, Keith B

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HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence von Huynh, TuAnh Ngoc, Luo, Shukun, Pensinger, Daniel, Sauer, John-Demian, Tong, Liang, Woodward, Joshua J.

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Antimalarial Drugs as Immune Modulators: New Mechanisms for Old Drugs von An, Jie, Minie, Mark, Sasaki, Tomikazu, Woodward, Joshua J, Elkon, Keith B

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Sustained Control of Pyruvate Carboxylase by the Essential Second Messenger Cyclic di-AMP in Bacillus subtilis von Krüger, Larissa, Herzberg, Christina, Wicke, Dennis, Scholz, Patricia, Schmitt, Kerstin, Turdiev, Asan, Lee, Vincent T, Ischebeck, Till, Stülke, Jörg

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Cyclic dinucleotides at the forefront of innate immunity von Zaver, Shivam A., Woodward, Joshua J.

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A STING-based biosensor affords broad cyclic dinucleotide detection within single living eukaryotic cells von Pollock, Alex J., Zaver, Shivam A., Woodward, Joshua J.

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c-di-AMP Secreted by Intracellular Listeria monocytogenes Activates a Host Type I Interferon Response von Woodward, Joshua J, Iavarone, Anthony T, Portnoy, Daniel A

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Enhanced uptake of potassium or glycine betaine or export of cyclic-di-AMP restores osmoresistance in a high cyclic-di-AMP Lactococcus lactis mutant von Pham, Huong Thi, Nhiep, Nguyen Thi Hanh, Vu, Thu Ngoc Minh, Huynh, TuAnh Ngoc, Zhu, Yan, Huynh, Anh Le Diep, Chakrabortti, Alolika, Marcellin, Esteban, Lo, Raquel, Howard, Christopher B, Bansal, Nidhi, Woodward, Joshua J, Liang, Zhao-Xun, Turner, Mark S

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Too much of a good thing: regulated depletion of c-di-AMP in the bacterial cytoplasm von Huynh, TuAnh Ngoc, Woodward, Joshua J

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The cyclic dinucleotide c-di-AMP is an allosteric regulator of metabolic enzyme function von Sureka, Kamakshi, Choi, Philip H, Precit, Mimi, Delince, Matthieu, Pensinger, Daniel A, Huynh, TuAnh Ngoc, Jurado, Ashley R, Goo, Young Ah, Sadilek, Martin, Iavarone, Anthony T, Sauer, John-Demian, Tong, Liang, Woodward, Joshua J

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Expression of Cyclic GMP‐AMP Synthase in Patients With Systemic Lupus Erythematosus von An, Jie, Durcan, Laura, Karr, Reynold M., Briggs, Tracy A., Rice, Gillian I., Teal, Thomas H., Woodward, Joshua J., Elkon, Keith B.

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N-Ethyl-N-Nitrosourea-Induced Goldenticket Mouse Mutant Reveals an Essential Function of Sting in the In Vivo Interferon Response to Listeria monocytogenes and Cyclic Dinucleotides von Sauer, John-Demian, Sotelo-Troha, Katia, von Moltke, Jakob, Monroe, Kathryn M, Rae, Chris S, Brubaker, Sky W, Hyodo, Mamoru, Hayakawa, Yoshihiro, Woodward, Joshua J, Portnoy, Daniel A, Vance, Russell E

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Replication-Transcription Conflicts Generate R-Loops that Orchestrate Bacterial Stress Survival and Pathogenesis von Lang, Kevin S., Hall, Ashley N., Merrikh, Christopher N., Ragheb, Mark, Tabakh, Hannah, Pollock, Alex J., Woodward, Joshua J., Dreifus, Julia E., Merrikh, Houra

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Inhibition of Cyclic GMP‐AMP Synthase Using a Novel Antimalarial Drug Derivative in Trex1‐Deficient Mice von An, Jie, Woodward, Joshua J., Lai, Weinan, Minie, Mark, Sun, Xizhang, Tanaka, Lena, Snyder, Jessica M., Sasaki, Tomikazu, Elkon, Keith B.

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High-throughput interaction screens illuminate the role of c-di-AMP in cyanobacterial nighttime survival von Rubin, Benjamin E, Huynh, TuAnh Ngoc, Welkie, David G, Diamond, Spencer, Simkovsky, Ryan, Pierce, Emily C, Taton, Arnaud, Lowe, Laura C, Lee, Jenny J, Rifkin, Scott A, Woodward, Joshua J, Golden, Susan S

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Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State von McFarland, Adelle P., Luo, Shukun, Ahmed-Qadri, Fariha, Zuck, Meghan, Thayer, Elizabeth F., Goo, Young Ah, Hybiske, Kevin, Tong, Liang, Woodward, Joshua J.

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c‐di‐AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance and osmoregulation von Whiteley, Aaron T., Garelis, Nicholas E., Peterson, Bret N., Choi, Philip H., Tong, Liang, Woodward, Joshua J., Portnoy, Daniel A.

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Structural and functional studies of pyruvate carboxylase regulation by cyclic di-AMP in lactic acid bacteria von Choi, Philip H., Vu, Thu Minh Ngoc, Pham, Huong Thi, Woodward, Joshua J., Turner, Mark S., Tong, Liang

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