Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1) von Miyashiro, Julie, Woods, Keith W., Park, Chang H., Liu, Xuesong, Shi, Yan, Johnson, Eric F., Bouska, Jennifer J., Olson, Amanda M., Luo, Yan, Fry, Elizabeth H., Giranda, Vincent L., Penning, Thomas D.

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Akt Inhibitor A-443654 Interferes with Mitotic Progression by Regulating Aurora A Kinase Expression von Liu, Xuesong, Shi, Yan, Woods, Keith W., Hessler, Paul, Kroeger, Paul, Wilsbacher, Julie, Wang, Jieyi, Wang, Jean Y., Li, Chunying, Li, Qun, Rosenberg, Saul H., Giranda, Vincent L., Luo, Yan

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Synthesis and Biological Evaluation of 2-Indolyloxazolines as a New Class of Tubulin Polymerization Inhibitors. Discovery of A-289099 as an Orally Active Antitumor Agent von Li, Qun, Woods, Keith W., Claiborne, Akiyo, Gwaltney, II, Stephen L., Barr, Kenneth J., Liu, Gang, Gehrke, Laura, Credo, R.Bruce, Hui, Yu Hua, Lee, Jang, Warner, Robert B., Kovar, Peter, Nukkala, Michael A., Zielinski, Nicolette A., Tahir, Stephen K., Fitzgerald, Michael, Kim, Ki H., Marsh, Kennan, Frost, David, Ng, Shi-Chung, Rosenberg, Saul, Sham, Hing L.

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Pharmacological and Functional Comparison of the Polo-like Kinase Family:  Insight into Inhibitor and Substrate Specificity von Johnson, Eric F, Stewart, Kent D, Woods, Keith W, Giranda, Vincent L, Luo, Yan

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Synthesis and structure–activity relationship of 3,4′-bispyridinylethylenes: Discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment... von Li, Qun, Woods, Keith W., Thomas, Sheela, Zhu, Gui-Dong, Packard, Garrick, Fisher, John, Li, Tongmei, Gong, Jianchun, Dinges, Jurgen, Song, Xiaohong, Abrams, Jason, Luo, Yan, Johnson, Eric F., Shi, Yan, Liu, Xuesong, Klinghofer, Vered, Des Jong, Ron, Oltersdorf, Tilman, Stoll, Vincent S., Jakob, Clarissa G., Rosenberg, Saul H., Giranda, Vincent L.

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Optimal Classes of Chemotherapeutic Agents Sensitized by Specific Small-Molecule Inhibitors of Akt In Vitro and In Vivo von Shi, Yan, Liu, Xuesong, Han, Edward K., Guan, Ran, Shoemaker, Alexander R., Oleksijew, Anatol, Woods, Keith W., Fisher, John P., Klinghofer, Vered, Lasko, Loren, McGonigal, Thomas, Li, Qun, Rosenberg, Saul H., Giranda, Vincent L., Luo, Yan

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Potent, Orally Active Heterocycle-Based Combretastatin A-4 Analogues:  Synthesis, Structure−Activity Relationship, Pharmacokinetics, and In Vivo Antitumor Activity Evaluation von Wang, Le, Woods, Keith W, Li, Qun, Barr, Kenneth J, McCroskey, Richard W, Hannick, Steven M, Gherke, Laura, Credo, R. Bruce, Hui, Yu-Hua, Marsh, Kennan, Warner, Robert, Lee, Jang Y, Zielinski-Mozng, Nicolette, Frost, David, Rosenberg, Saul H, Sham, Hing L

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Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo von Luo, Yan, Shoemaker, Alexander R, Liu, Xuesong, Woods, Keith W, Thomas, Sheela A, de Jong, Ron, Han, Edward K, Li, Tongmei, Stoll, Vincent S, Powlas, Jessica A, Oleksijew, Anatol, Mitten, Michael J, Shi, Yan, Guan, Ran, McGonigal, Thomas P, Klinghofer, Vered, Johnson, Eric F, Leverson, Joel D, Bouska, Jennifer J, Mamo, Mulugeta, Smith, Richard A, Gramling-Evans, Emily E, Zinker, Bradley A, Mika, Amanda K, Nguyen, Phong T, Oltersdorf, Tilman, Rosenberg, Saul H, Li, Qun, Giranda, Vincent L

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Biological Activity of A-289099: An Orally Active Tubulin-binding Indolyloxazoline Derivative von Tahir, Stephen K, Nukkala, Michael A, Zielinski Mozny, Nicolette A, Credo, R Bruce, Warner, Robert B, Li, Qun, Woods, Keith W, Claiborne, Akiyo, Gwaltney, 2nd, Stephen L, Frost, David J, Sham, Hing L, Rosenberg, Saul H, Ng, Shi-Chung

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Aminopyrimidinone Cdc7 Kinase Inhibitors von Woods, Keith W., Lai, Chunqiu, Miyashiro, Julie M., Tong, Yunsong, Florjancic, Alan S., Han, Edward K., Soni, Niru, Shi, Yan, Lasko, Loren, Leverson, Joel D., Johnson, Eric F., Shoemaker, Alexander R., Penning, Thomas D.

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Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension von Zhu, Gui-Dong, Gandhi, Viraj B, Gong, Jianchun, Thomas, Sheela, Woods, Keith W, Song, Xiaohong, Li, Tongmei, Diebold, R. Bruce, Luo, Yan, Liu, Xuesong, Guan, Ran, Klinghofer, Vered, Johnson, Eric F, Bouska, Jennifer, Olson, Amanda, Marsh, Kennan C, Stoll, Vincent S, Mamo, Mulugeta, Polakowski, James, Campbell, Thomas J, Martin, Ruth L, Gintant, Gary A, Penning, Thomas D, Li, Qun, Rosenberg, Saul H, Giranda, Vincent L

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Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors von Woods, Keith W., Fischer, John P., Claiborne, Akiyo, Li, Tongmei, Thomas, Sheela A., Zhu, Gui-Dong, Diebold, Robert B., Liu, Xuesong, Shi, Yan, Klinghofer, Vered, Han, Edward K., Guan, Ran, Magnone, Shayna R., Johnson, Eric F., Bouska, Jennifer J., Olson, Amanda M., Jong, Ron de, Oltersdorf, Tilman, Luo, Yan, Rosenberg, Saul H., Giranda, Vincent L., Li, Qun

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Benzimidazolones and indoles as non-thiol farnesyltransferase inhibitors based on tipifarnib scaffold: synthesis and activity von Li, Qun, Li, Tongmei, Woods, Keith W., Gu, Wen-Zhen, Cohen, Jerry, Stoll, Vincent S., Galicia, Tomas, Hutchins, Charles, Frost, David, Rosenberg, Saul H., Sham, Hing L.

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The Endocyclic Restriction Test:  Oxygen Transfer from N-Sulfonyl Oxaziridines to Alkenes von Anderson, David R, Woods, Keith W, Beak, Peter

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Isoquinoline–pyridine-based protein kinase B/Akt antagonists: SAR and in vivo antitumor activity von Zhu, Gui-Dong, Gong, Jianchun, Claiborne, Akiyo, Woods, Keith W., Gandhi, Viraj B., Thomas, Sheela, Luo, Yan, Liu, Xuesong, Shi, Yan, Guan, Ran, Magnone, Shayna R., Klinghofer, Vered, Johnson, Eric F., Bouska, Jennifer, Shoemaker, Alexander, Oleksijew, Anatol, Stoll, Vincent S., Jong, Ron De, Oltersdorf, Tilman, Li, Qun, Rosenberg, Saul H., Giranda, Vincent L.

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Design, synthesis, and activity of achiral analogs of 2-quinolones and indoles as non-thiol farnesyltransferase inhibitors von Li, Qun, Woods, Keith W., Wang, Weibo, Lin, Nan-Horng, Claiborne, Akiyo, Gu, Wen-zhen, Cohen, Jerry, Stoll, Vincent S., Hutchins, Charles, Frost, David, Rosenberg, Saul H., Sham, Hing L.

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Identification of a novel 3,5-disubstituted pyridine as a potent, selective, and orally active inhibitor of Akt1 kinase von Thomas, Sheela A., Li, Tongmei, Woods, Keith W., Song, Xiaohong, Packard, Garrick, Fischer, John P., Diebold, Robert B., Liu, Xuesong, Shi, Yan, Klinghofer, Vered, Johnson, Eric F., Bouska, Jennifer J., Olson, Amanda, Guan, Ran, Magnone, Shayna R., Marsh, Kennan, Luo, Yan, Rosenberg, Saul H., Giranda, Vincent L., Li, Qun

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Thiazole analogues of the NSAID indomethacin as selective COX-2 Inhibitors von Woods, Keith W., McCroskey, Richard W., Michaelides, Michael R., Wada, Carol K., Hulkower, Keren I., Bell, Randy L.

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Synthesis and activity of 1-aryl-1'-imidazolyl methyl ethers as non-thiol farnesyltransferase inhibitors von QUN LI, WANG, Gary T, HUTCHINS, Charles, FROST, David, ROSENBERG, Saul H, SHAM, Hing L, TONGMEI LI, GWALTNEY, Stephen L, WOODS, Keith W, CLAIBORNE, Akiyo, XILU WANG, WENDY GU, COHEN, Jerry, STOLL, Vincent S

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Heteroarylmethoxyphenylalkoxyiminoalkylcarboxylic Acids as Leukotriene Biosynthesis Inhibitors von Kolasa, Teodozyj, Gunn, David E, Bhatia, Pramila, Woods, Keith W, Gane, Todd, Stewart, Andrew O, Bouska, Jennifer B, Harris, Richard R, Hulkower, Keren I, Malo, Peter E, Bell, Randy L, Carter, George W, Brooks, Clint D. W

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