The BCR-ABL story: bench to bedside and back von Wong, Stephane, Witte, Owen N

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Will PAXgene substitute formalin? A morphological and molecular comparative study using a new fixative system von Belloni, Benedetta, Lambertini, Chiara, Nuciforo, Paolo, Phillips, Jay, Bruening, Eric, Wong, Stephane, Dummer, Reinhard

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Phosphoinositide 3-kinase signaling is essential for ABL oncogene–mediated transformation of B-lineage cells von Kharas, Michael G., Deane, Jonathan A., Wong, Stephane, O’Bosky, Karen R., Rosenberg, Naomi, Witte, Owen N., Fruman, David A.

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Cell context–specific effects of the BCR-ABL oncogene monitored in hematopoietic progenitors von Wong, Stephane, McLaughlin, Jami, Cheng, Donghui, Witte, Owen N.

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Positron emission tomography imaging analysis of G2A as a negative modifier of lymphoid leukemogenesis initiated by the BCR-ABL oncogene von Le, Lu Q, Kabarowski, Janusz H.S, Wong, Stephane, Nguyen, Khoi, Gambhir, Sanjiv S, Witte, Owen N

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International Scale (IS)-Standardized BCR-ABL1 Digital Polymerase Chain Reaction (dPCR) Assays Using ABL1, BCR, and GUS Control Genes for Measuring Deep Molecular Response (MR) in... von Huang, Alice, Salcius, Jennifer, Wong, Connie, Wong, Stephane, Wang, Sha-Sha

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BCR/ABL Inhibition by an Escort/Phosphatase Fusion Protein von Lim, Young-Mi, Wong, Stephane, Lau, Gary, Witte, Owen N., Colicelli, John

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IL-3 Receptor Signaling Is Dispensable for BCR-ABL-Induced Myeloproliferative Disease von Wong, Stephane, McLaughlin, Jami, Cheng, Donghui, Shannon, Kevin, Robb, Lorraine, Witte, Owen N.

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Abstract 3491: Absolute quantification of EGFR activation and resistance mutations as well as copy number in circulating nucleic acids by droplet digital PCR von Kristof, Jessica, Bruening, Eric, Wong, Stephane, Sankar, Sabita

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Regulation of the Oncogenic Activity of BCR-ABL by a Tightly Bound Substrate Protein RIN1 von Afar, Daniel E.H, Han, Limin, McLaughlin, Jami, Wong, Stephane, Dhaka, Ajay, Parmar, Kalindi, Rosenberg, Naomi, Witte, Owen N, Colicelli, John

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Abstract CT237: Evaluation of in vivo chimeric antigen receptor (CAR) transgene levels in patients (pts) treated with tisagenlecleucel von Awasthi, Rakesh, Mueller, Karen Thudium, Yanik, Gregory A., Tam, Constantine S., Rives, Susana, McGuirk, Joseph P., Pulsipher, Michael A., Boyer, Michael W., Jaeger, Ulrich, Baruchel, Andre, Myers, Gary D., Borchmann, Peter, Schuster, Stephen J., Stefanski, Heather, Bishop, Michael, Waldron, Edward R., Anak, Ozlem, Chakraborty, Abhijit, Bleickardt, Eric, Wong, Stephane, Pacaud, Lida Bubuteishvili, Waller, Edmund K., Maude, Shannon L.

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Abstract CT077: Potential utility of minimal residual disease (MRD) to identify relapse in pediatric and young adult (AYA) B-cell acute lymphoblastic leukemia (B-ALL) patients trea... von Pulsipher, Michael A., Han, Xia, Quigley, Máire, Kari, Gabor, Rives, Susana, Laetsch, Theodore W., Myers, Gary D., Hiramatsu, Hidefumi, Yanik, Gregory A., Qayed, Muna, Driscoll, Timothy, Boyer, Michael W., Stefanski, Heather, Buchner, Jochen, Baruchel, Andre, Bader, Peter, Yi, Lan, Kalfoglou, Creton, Robins, Harlan, Yusko, Erik, Gorgun, Gullu, Bleickardt, Eric, Wong, Stephane, Grupp, Stephan A.

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Evaluation of In Vivo CAR Transgene Levels in Relapsed/Refractory Pediatric and Young Adult ALL and Adult DLBCL Tisagenlecleucel-Treated Patients von Awasthi, Rakesh, Mueller, Karen Thudium, Yanik, Gregory A., Tam, Constantine S., Rives, Susana, McGuirk, Joseph P., Pulsipher, Michael A., Boyer, Michael W., Jaeger, Ulrich, Baruchel, Andre, Myers, Gary Douglas, Balke-Want, Hyatt, Schuster, Stephen J., Stefanski, Heather, Bishop, Michael R., Waldron, Edward R., Anak, Özlem, Chakraborty, Abhijit, Bleickardt, Eric, Wong, Stephane, Bubuteishvili Pacaud, Lida, Waller, Edmund K., Maude, Shannon L.

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Molecular Detection of Minimal Residual Disease Precedes Morphological Relapse and Could be Used to Identify Relapse in Pediatric and Young Adult B-Cell Acute Lymphoblastic Leukemi... von Pulsipher, Michael A., Han, Xia, Quigley, Máire, Kari, Gabor, Rives, Susana, Laetsch, Theodore W., Myers, Gary Douglas, Hiramatsu, Hidefumi, Yanik, Gregory A., Qayed, Muna, Driscoll, Timothy, Boyer, Michael W., Stefanski, Heather, Büchner, Jochen, Baruchel, Andre, Bader, Peter, Yi, Lan, Kalfoglou, Creton, Robins, Harlan, Yusko, Erik, Görgün, Güllü, Bleickardt, Eric, Wong, Stephane, Grupp, Stephan A.

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Abstract 39: Clinical assessment of PTEN mutation in FFPE tissue: comparison of Sanger sequencing, immunohistochemistry and chromogenic in situ hybridization methods von Sakrison, Kellen, Wright, Jennifer, Bruening, Eric, Wong, Stephane, Spittle, Cynthia, Sankar, Sabita, Galderisi, Chad

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The BCR-ABL35INS insertion/truncation mutant is kinase-inactive and does not contribute to tyrosine kinase inhibitor resistance in chronic myeloid leukemia von O'Hare, Thomas, Zabriskie, Matthew S., Eide, Christopher A., Agarwal, Anupriya, Adrian, Lauren T., You, Huihong, Corbin, Amie S., Yang, Fei, Press, Richard D., Rivera, Victor M., Toplin, Julie, Wong, Stephane, Deininger, Michael W., Druker, Brian J.

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Treatment-free remission (TFR) in patients (pts) with chronic myeloid leukemia in chronic phase (CML-CP) treated with second-line nilotinib (NIL): First results from the ENESTop st... von Hughes, Timothy P, Boquimpani, Carla, Kim, Dong-Wook, Benyamini, Noam, Clementino, Nelma Cristina D., Shuvaev, Vasily, Ailawadhi, Sikander, Lipton, Jeffrey Howard, Turkina, Anna G., De Paz Arias, Raquel, Moiraghi, Beatriz, Nicolini, Franck E., Dengler, Jolanta, Sacha, Tomasz, Takahashi, Naoto, Fellague-Chebra, Rafik, Acharya, Sandip, Wong, Stephane, Jin, Yu, Mahon, Francois-Xavier

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Will PAXgene substitute formalin? A morphological and molecular comparative study using a new fixative system von BELLONI, Benedetta, LAMBERTINI, Chiara, NUCIFORO, Paolo, PHILLIPS, Jay, BRUENING, Eric, WONG, Stephane, DUMMER, Reinhard

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Will PAXgene substitute formalin? A morphological and molecular comparative study using a new fixative system von Belloni, Benedetta, Lambertini, Chiara, Nuciforo, Paolo, Phillips, Jay, Bruening, Eric, Wong, Stephane, Dummer, Reinhard

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Next-Generation Sequencing of the BCR-ABL1 Kinase Domain and Neighboring Domains Associated with Therapy Resistance von Li, Jin, Liu, Weihua, Yan, Zhenyu, Fang, Peng, Darwanto, Agus, Pelak, Kim, Toplin, Julie, Anoe, Kim, Spittle, Cindy, Galderisi, Chad, Wong, Stephane

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