Concise Review: Erythroid Versus Myeloid Lineage Commitment: Regulating the Master Regulators von Wolff, Linda, Humeniuk, Rita

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UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes von Sera, Yasuyuki, Nakata, Yuichiro, Ueda, Takeshi, Yamasaki, Norimasa, Koide, Shuhei, Kobayashi, Hiroshi, Ikeda, Ken-ichiro, Kobatake, Kohei, Iwasaki, Masayuki, Oda, Hideaki, Wolff, Linda, Kanai, Akinori, Nagamachi, Akiko, Inaba, Toshiya, Sotomaru, Yusuke, Ichinohe, Tatsuo, Koizumi, Miho, Miyakawa, Yoshihiko, Honda, Zen-ichiro, Iwama, Atsushi, Suda, Toshio, Takubo, Keiyo, Honda, Hiroaki

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p15Ink4b Functions in determining hematopoietic cell fates: Implications for its role as a tumor suppressor von Wolff, Linda, Bies, Juraj

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Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2 von Ueda, Takeshi, Nagamachi, Akiko, Takubo, Keiyo, Yamasaki, Norimasa, Matsui, Hirotaka, Kanai, Akinori, Nakata, Yuichiro, Ikeda, Kenichiro, Konuma, Takaaki, Oda, Hideaki, Wolff, Linda, Honda, Zen-ichiro, Wu, Xudong, Helin, Kristian, Iwama, Atsushi, Suda, Toshio, Inaba, Toshiya, Honda, Hiroaki

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Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus von Li, Qing, Haigis, Kevin M., McDaniel, Andrew, Harding-Theobald, Emily, Kogan, Scott C., Akagi, Keiko, Wong, Jasmine C.Y., Braun, Benjamin S., Wolff, Linda, Jacks, Tyler, Shannon, Kevin

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Identification of cooperative genes for E2A‐PBX1 to develop acute lymphoblastic leukemia von Sera, Yasuyuki, Yamasaki, Norimasa, Oda, Hideaki, Nagamachi, Akiko, Wolff, Linda, Inukai, Takeshi, Inaba, Toshiya, Honda, Hiroaki

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Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression von Ueda, Takeshi, Nakata, Yuichiro, Nagamachi, Akiko, Yamasaki, Norimasa, Kanai, Akinori, Sera, Yasuyuki, Sasaki, Masato, Matsui, Hirotaka, Honda, Zen-ichiro, Oda, Hideaki, Wolff, Linda, Inaba, Toshiya, Honda, Hiroaki

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Three Murine Leukemia Virus Integration Regions within 100 Kilobases Upstream of c-myb Are Proximal to the 5′ Regulatory Region of the Gene through DNA Looping von Zhang, Junfang, Markus, Jan, Bies, Juraj, Paul, Thomas, Wolff, Linda

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Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras von Lauchle, Jennifer O., Kim, Doris, Le, Doan T., Akagi, Keiko, Crone, Michael, Krisman, Kimberly, Warner, Kegan, Bonifas, Jeannette M., Li, Qing, Coakley, Kristen M., Diaz-Flores, Ernesto, Gorman, Matthew, Przybranowski, Sally, Tran, Mary, Kogan, Scott C., Roose, Jeroen P., Copeland, Neal G., Jenkins, Nancy A., Parada, Luis, Wolff, Linda, Sebolt-Leopold, Judith, Shannon, Kevin

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Covalent Attachment of the SUMO-1 Protein to the Negative Regulatory Domain of the c-Myb Transcription Factor Modifies Its Stability and Transactivation Capacity von Bies, Juraj, Markus, Ján, Wolff, Linda

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Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency von Ikeda, Kenichiro, Ueda, Takeshi, Yamasaki, Norimasa, Nakata, Yuichiro, Sera, Yasuyuki, Nagamachi, Akiko, Miyama, Takahiko, Kobayashi, Hiroshi, Takubo, Keiyo, Kanai, Akinori, Oda, Hideaki, Wolff, Linda, Honda, Zen-ichiro, Ichinohe, Tatsuo, Matsubara, Akio, Suda, Toshio, Inaba, Toshiya, Honda, Hiroaki

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Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia von Nakata, Yuichiro, Ueda, Takeshi, Nagamachi, Akiko, Yamasaki, Norimasa, Ikeda, Ken-ichiro, Sera, Yasuyuki, Takubo, Keiyo, Kanai, Akinori, Oda, Hideaki, Sanada, Masashi, Ogawa, Seishi, Tsuji, Kohichiro, Ebihara, Yasuhiro, Wolff, Linda, Honda, Zen-ichiro, Suda, Toshio, Inaba, Toshiya, Honda, Hiroaki

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PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomas von Baron, Beverly W, Anastasi, John, Hyjek, Elizabeth M, Bies, Juraj, Reddy, Poluru L, Dong, Jingfang, Joseph, Loren, Thirman, Michael J, Wroblewski, Kristen, Wolff, Linda, Baron, Joseph M

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Stress-induced Inactivation of the c-Myb Transcription Factor through Conjugation of SUMO-2/3 Proteins von Šramko, Marek, Markus, Ján, Kabát, Juraj, Wolff, Linda, Bies, Juraj

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CIZ1, a p21Cip1/Waf1-interacting protein, functions as a tumor suppressor in vivo von Nishibe, Rio, Watanabe, Wataru, Ueda, Takeshi, Yamasaki, Norimasa, Koller, Richard, Wolff, Linda, Honda, Zen-ichiro, Ohtsubo, Motoaki, Honda, Hiroaki

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Loss of the tumor suppressor p15Ink4b enhances myeloid progenitor formation from common myeloid progenitors von Rosu-Myles, Michael, Taylor, Barbara J, Wolff, Linda

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Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies von Wong, Jasmine C.Y., Zhang, Yan, Lieuw, Kenneth H., Tran, Mary T., Forgo, Erna, Weinfurtner, Kelley, Alzamora, Pilar, Kogan, Scott C., Akagi, Keiko, Wolff, Linda, Le Beau, Michelle M., Killeen, Nigel, Shannon, Kevin

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A Moloney Murine Leukemia Virus-Based Retrovirus with 4070A Long Terminal Repeat Sequences Induces a High Incidence of Myeloid as Well as Lymphoid Neoplasms von Wolff, Linda, Koller, Richard, Hu, Xinrong, Anver, Miriam R

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Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, Causes Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7 von Nagamachi, Akiko, Matsui, Hirotaka, Asou, Hiroya, Ozaki, Yuko, Aki, Daisuke, Kanai, Akinori, Takubo, Keiyo, Suda, Toshio, Nakamura, Takuro, Wolff, Linda, Honda, Hiroaki, Inaba, Toshiya

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Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents von Dail, Monique, Li, Qing, McDaniel, Andrew, Wong, Jason, Akagi, Keiko, Huang, Ben, Kang, Hio Chung, Kogan, Scott C, Shokat, Kevan, Wolff, Linda, Braun, Benjamin S, Shannon, Kevin

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