Probing Mechanisms and Therapeutic Potential of γ-Secretase in Alzheimer's Disease von Wolfe, Michael S

Volltext

Tau Mutations in Neurodegenerative Diseases von Wolfe, Michael S.

Volltext

Nicastrin functions to sterically hinder γ-secretase–substrate interactions driven by substrate transmembrane domain von Bolduc, David M., Montagna, Daniel R., Gu, Yongli, Selkoe, Dennis J., Wolfe, Michael S.

Volltext

Intramembrane Proteolysis: Theme and Variations von Wolfe, Michael S., Kopan, Raphael

Volltext

Emerging structures and dynamic mechanisms of γ-secretase for Alzheimer's disease von Miao, Yinglong, Wolfe, Michael S

Volltext

Structure and Function of the γ‑Secretase Complex von Wolfe, Michael S

Volltext

The amyloid-beta forming tripeptide cleavage mechanism of γ-secretase von Bolduc, David M, Montagna, Daniel R, Seghers, Matthew C, Wolfe, Michael S, Selkoe, Dennis J

Volltext

Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes von Devkota, Sujan, Zhou, Rui, Nagarajan, Vaishnavi, Maesako, Masato, Do, Hung, Noorani, Arshad, Overmeyer, Caitlin, Bhattarai, Sanjay, Douglas, Justin T., Saraf, Anita, Miao, Yinglong, Ackley, Brian D., Shi, Yigong, Wolfe, Michael S.

Volltext

Unraveling the complexity of γ-secretase von Wolfe, Michael S.

Volltext

Sorting Out Presenilins in Alzheimer’s Disease von Wolfe, Michael S., Yankner, Bruce A.

Volltext

A neurodegeneration checkpoint mediated by REST protects against the onset of Alzheimer’s disease von Aron, Liviu, Qiu, Chenxi, Ngian, Zhen Kai, Liang, Marianna, Drake, Derek, Choi, Jaejoon, Fernandez, Marty A., Roche, Perle, Bunting, Emma L., Lacey, Ella K., Hamplova, Sara E., Yuan, Monlan, Wolfe, Michael S., Bennett, David A., Lee, Eunjung A., Yankner, Bruce A.

Volltext

Mechanisms of γ‑Secretase Activation and Substrate Processing von Bhattarai, Apurba, Devkota, Sujan, Bhattarai, Sanjay, Wolfe, Michael S, Miao, Yinglong

Volltext

Substrate recognition and processing by γ-secretase von Wolfe, Michael S.

Volltext

Therapeutic strategies for Alzheimer's disease von Wolfe, Michael S

Volltext

A Portrait of Alzheimer Secretases: New Features and Familiar Faces von Esler, William P., Wolfe, Michael S.

Volltext

A G-Rich element forms a G-quadruplex and regulates BACE1 mRNA alternative splicing von Fisette, Jean-François, Montagna, Daniel R., Mihailescu, Mihaela-Rita, Wolfe, Michael S.

Volltext

γ-Secretase inhibitors and modulators for Alzheimer's disease von Wolfe, Michael S.

Volltext

Reconstitution of Intramembrane Proteolysis in vitro Reveals That Pure Rhomboid Is Sufficient for Catalysis and Specificity von Urban, Sinisa, Wolfe, Michael S., Südhof, Thomas C.

Volltext

[gamma]-Secretase inhibitors and modulators for Alzheimer's disease von Wolfe, Michael S

Volltext

Effects of presenilin-1 familial Alzheimer’s disease mutations on γ-secretase activation for cleavage of amyloid precursor protein von Do, Hung N., Devkota, Sujan, Bhattarai, Apurba, Wolfe, Michael S., Miao, Yinglong

Volltext