Inhibition of HIV replication by amino-sugar derivatives von Fleet, George W.J., Karpas, Abraham, Dwek, Raymond A., Fellows, Linda E., Tyms, A.S., Petursson, Sigthor, Namgoong, Sung K., Ramsden, Nigel G., Smith, Paul W., Son, Jong Chan, Wilson, Francis, Witty, David R., Jacob, Gary S., Rademacher, Thomas W.

Volltext

Synthesis of oxetanocin von Wilson, F.X., Fleet, G.W.J., Vogt, K., Wang, Y., Witty, D.R., Choi, S., Storer, R., Myers, P.L., Wallis, C.J.

Volltext

Practical synthesis of deoxymannojirimycin and mannonolactam from L-gulonolactone.: Synthesis of L-deoxymannojirimycin and L-mannonolactam from D-gulonolactone von Fleet, George W.J., Ramsden, Nigel G., Witty, David R.

Volltext

A practical synthesis of deoxymannojirimycin and of (2s,3R,4R,5R)-3,4,5-trihydroxypipecolic acid from D-glucose von Fleet, George W.J., Ramsden, Nigel G., Witty, David R

Volltext

The antimicrobial natural product chuangxinmycin and Some synthetic analogues are potent and selective inhibitors of bacterial tryptophanyl tRNA synthetase von Brown, Murray J., Carter, Paul S., Fenwick, Ashley E., Fosberry, Andrew P., Hamprecht, Dieter W., Hibbs, Martin J., Jarvest, Richard L., Mensah, Lucy, Milner, Peter H., O'Hanlon, Peter J., Pope, Andrew J., Richardson, Christine M., West, Andrew, Witty, David R.

Volltext

Ring contraction of 2-o-trifluoromethanesulphonates of α-hydroxy-γ-lactones to oxetane carboxylic esters von Witty, D.R, Fleet, G.W.J, Vogt, K, Wilson, F.X, Wang, Y, Storer, R, Myers, P.L, Wallis, C.J

Volltext

Bicyclic heteroarylpiperazines as selective brain penetrant 5-HT6 receptor antagonists von AHMED, Mahmood, BRIGGS, Michael A, JOHNSON, Christopher N, MEDHURST, Andrew D, MITCHELL, Darren J, MOSS, Stephen F, POWLES, Jenifer, SEAL, Jon T, STEAN, Tania O, STEMP, Geoffrey, THOMPSON, Mervyn, TRAIL, Brenda, BROMIDGE, Steven M, UPTON, Neil, WINBORN, Kim, WITTY, David R, BUCK, Tania, CAMPBELL, Lorraine, DEEKS, Nigel J, GARNER, Ashley, GORDON, Laurie, HAMPRECHT, Dieter W, HOLLAND, Vicky

Volltext

Approach to oxetane and furan nucleosides with an anomeric carbon substituent: Nucleophilic substitution at highly hindered α-bromo-oxetane- and -tetrahydrofuran-carboxylates von Choi, S., Witty, D.R., Fleet, G.W.J., Myer, P.L., Storer, R., Wailis, C.J., Watkin, D., Pearce, L.

Volltext

Definition of the heterocyclic pharmacophore of bacterial methionyl tRNA synthetase inhibitors: potent antibacterially active non-quinolone analogues von Jarvest, Richard L, Armstrong, Sula A, Berge, John M, Brown, Pamela, Elder, John S, Brown, Murray J, Copley, Royston C.B, Forrest, Andrew K, Hamprecht, Dieter W, O'Hanlon, Peter J, Mitchell, Darren J, Rittenhouse, Stephen, Witty, David R

Volltext

Ring contraction of 3-deoxy-2-O-trifluoromethanesulphonates of α-hydroxy-γ-lactones to oxetanes von Witty, D.R., Fleet, G.W.J., Choi, S., Vogt, K., Wilson, F.X., Wang, Y., Storer, R., Myers, P.L., Wallis, C.J.

Volltext

Oxetane nucleosides with fluorine and azide substituents : nucleophilic displacements on an oxetane ring von WANG, Y, FLEET, G. W. J, PEACH, J. M, WILSON, F. X, STORER, R, MYERS, P. L, WALLIS, C. J, DOHERTY, O, WATKIN, D. J, VOGT, K, WITTY, D. R

Volltext

Short syntheses of D-deoxymannojirimycin and D-mannonolactam from L-gulonolactone and of L-deoxymannojirimycin and L-mannonolactam from D-gulonolactone von Fleet, George W.J., Ramsden, Nigel G., Witty, David R.

Volltext

Attempted ring contraction of α-triflates of 3-azido- and 3-fluoro-γ-lactones to oxetanes von Elliott, R.P., Fleet, G.W.J., Vogt, K., Wilson, F.X., Wang, Y., Witty, D.R., Storer, R., Myers, P.L., Wallis, C.J.

Volltext

Synthesis of the potent antiviral oxetane nucleoside epinoroxetanocin from D-lyxonolactone von Wang, Y., Fleet, G.W.J., Storer, R., Myers, P.L., Wallis, C.J., Doherty, O., Watkin, D.J., Vogt, K., Witty, D.R., Wilson, F.X., Peach, J.M.

Volltext

Proton abstraction and electrophilic quench at C-2 of imidazolidines von Coldham, Iain, Judkins, Robert A., Witty, David R.

Volltext

N,N′-Bisacylimidazolidines from 1,2-Diamines von Coldham, Iain, Houdayer, Philippe M. A., Judkins, Robert A., Witty, David R.

Volltext

Oxetane nucleosides with fluorine and azide substitutents: nucleophilic displacements on an oxetane ring von Wang, Y., Fleet, G.W.J., Wilson, F.X., Storer, R., Wallis, C.J., Doherty, O., Watkin, D.J., Vogt, K., Witty, D.R., Peach, J.M.

Volltext

One-Pot Synthesis of N,N’-Bisacylimidazolidines; Potential New Acyl Anion Equivalents von Coldham, Iain, Houdayer, Philippe M. A., Judkins, Robert A., Witty, David R.

Volltext

Synthesis of conformationally restricted analogues of the tryptophanyl tRNA synthetase inhibitor indolmycin von Witty, David R., Walker, Graham, Bateson, John H., O'Hanlon, Peter J., Eggleston, Drake S., Haltiwanger, R.Curtis

Volltext

Structure-activity dependency of new bacterial tryptophanyl tRNA synthetase inhibitors von Witty, David R., Walker, Graham, Bateson, John H., O'Hanlon, Peter J., Cassels, Robert

Volltext