Enhanced CAR–T cell activity against solid tumors by vaccine boosting through the chimeric receptor von Ma, Leyuan, Dichwalkar, Tanmay, Chang, Jason Y. H., Cossette, Benjamin, Garafola, Daniel, Zhang, Angela Q., Fichter, Michael, Wang, Chensu, Liang, Simon, Silva, Murillo, Kumari, Sudha, Mehta, Naveen K., Abraham, Wuhbet, Thai, Nikki, Li, Na, Wittrup, K. Dane, Irvine, Darrell J.

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What, Why, Where, and When: Bringing Timing to Immuno-Oncology von Rothschilds, Adrienne M., Wittrup, K. Dane

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Spatiotemporally programming cytokine immunotherapies through protein engineering von Santollani, Luciano, Wittrup, K Dane

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A modeling analysis of the effects of molecular size and binding affinity on tumor targeting von Schmidt, Michael M, Wittrup, K Dane

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Maximizing response to intratumoral immunotherapy in mice by tuning local retention von Momin, Noor, Palmeri, Joseph R., Lutz, Emi A., Jailkhani, Noor, Mak, Howard, Tabet, Anthony, Chinn, Magnolia M., Kang, Byong H., Spanoudaki, Virginia, Hynes, Richard O., Wittrup, K. Dane

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An engineered protein antagonist of K-Ras/B-Raf interaction von Kauke, Monique J., Traxlmayr, Michael W., Parker, Jillian A., Kiefer, Jonathan D., Knihtila, Ryan, McGee, John, Verdine, Greg, Mattos, Carla, Wittrup, K. Dane

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Biophysical properties of the clinical-stage antibody landscape von Jain, Tushar, Sun, Tingwan, Durand, Stéphanie, Hall, Amy, Houston, Nga Rewa, Nett, Juergen H., Sharkey, Beth, Bobrowicz, Beata, Caffry, Isabelle, Yu, Yao, Cao, Yuan, Lynaugh, Heather, Brown, Michael, Baruah, Hemanta, Gray, Laura T., Krauland, Eric M., Xu, Yingda, Vásquez, Maximiliano, Wittrup, K. Dane

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Reduction of Nonspecificity Motifs in Synthetic Antibody Libraries von Kelly, Ryan L., Le, Doris, Zhao, Jessie, Wittrup, K. Dane

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Antibody tumor penetration: Transport opposed by systemic and antigen-mediated clearance von Thurber, Greg M., Schmidt, Michael M., Wittrup, K. Dane

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Yeast surface display for protein engineering and characterization von Gai, S Annie, Wittrup, K Dane

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Manipulating the Selection Forces during Affinity Maturation to Generate Cross-Reactive HIV Antibodies von Wang, Shenshen, Mata-Fink, Jordi, Kriegsman, Barry, Hanson, Melissa, Irvine, Darrell J., Eisen, Herman N., Burton, Dennis R., Wittrup, K. Dane, Kardar, Mehran, Chakraborty, Arup K.

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A mechanistic compartmental model for total antibody uptake in tumors von Thurber, Greg M., Dane Wittrup, K.

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Picomolar Affinity Fibronectin Domains Engineered Utilizing Loop Length Diversity, Recursive Mutagenesis, and Loop Shuffling von Hackel, Benjamin J., Kapila, Atul, Dane Wittrup, K.

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Antigen specificity can be irrelevant to immunocytokine efficacy and biodistribution von Tzeng, Alice, Kwan, Byron H., Opel, Cary F., Navaratna, Tejas, Wittrup, K. Dane

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Computational design of antibody-affinity improvement beyond in vivo maturation von Wittrup, K Dane, Tidor, Bruce, Lippow, Shaun M

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Directed evolution of a secretory leader for the improved expression of heterologous proteins and full-length antibodies in Saccharomyces cerevisiae von Rakestraw, J. Andy, Sazinsky, Stephen L, Piatesi, Andrea, Antipov, Eugene, Wittrup, K. Dane

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Practical Theoretic Guidance for the Design of Tumor-Targeting Agents von Wittrup, K. Dane, Thurber, Greg M., Schmidt, Michael M., Rhoden, John J.

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Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies von Lutz, Emi A., Agarwal, Yash, Momin, Noor, Cowles, Sarah C., Palmeri, Joseph R., Duong, Ellen, Hornet, Vladlena, Sheen, Allison, Lax, Brianna M., Rothschilds, Adrienne M., Irvine, Darrell J., Spranger, Stefani, Wittrup, K. Dane

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Synergistic Innate and Adaptive Immune Response to Combination Immunotherapy with Anti-Tumor Antigen Antibodies and Extended Serum Half-Life IL-2 von Zhu, Eric F., Gai, Shuning A., Opel, Cary F., Kwan, Byron H., Surana, Rishi, Mihm, Martin C., Kauke, Monique J., Moynihan, Kelly D., Angelini, Alessandro, Williams, Robert T., Stephan, Matthias T., Kim, Jacob S., Yaffe, Michael B., Irvine, Darrell J., Weiner, Louis M., Dranoff, Glenn, Wittrup, K. Dane

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Directed evolution of broadly crossreactive chemokine-blocking antibodies efficacious in arthritis von Angelini, Alessandro, Miyabe, Yoshishige, Newsted, Daniel, Kwan, Byron H., Miyabe, Chie, Kelly, Ryan L., Jamy, Misha N., Luster, Andrew D., Wittrup, K. Dane

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