Regulation of T cell alloimmunity by PI3Kγ and PI3Kδ von Uehara, Mayuko, McGrath, Martina M., Ohori, Shunsuke, Solhjou, Zhabiz, Banouni, Naima, Routray, Sujit, Evans, Catherine, DiNitto, Jonathan P., Elkhal, Abdallah, Turka, Laurence A., Strom, Terry B., Tullius, Stefan G., Winkler, David G., Azzi, Jamil, Abdi, Reza

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Sclerostin promotes the apoptosis of human osteoblastic cells: a novel regulation of bone formation von Sutherland, May Kung, Geoghegan, James C., Yu, Changpu, Turcott, Eileen, Skonier, John E., Winkler, David G., Latham, John A.

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The Selective Phosphoinoside-3-Kinase p110δ Inhibitor IPI-3063 Potently Suppresses B Cell Survival, Proliferation, and Differentiation von Chiu, Honyin, Mallya, Sharmila, Nguyen, Phuongthao, Mai, Annie, Jackson, Leandra V, Winkler, David G, DiNitto, Jonathan P, Brophy, Erin E, McGovern, Karen, Kutok, Jeffery L, Fruman, David A

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PI3Kγ is a molecular switch that controls immune suppression von Kaneda, Megan M., Messer, Karen S., Ralainirina, Natacha, Li, Hongying, Leem, Christopher J., Gorjestani, Sara, Woo, Gyunghwi, Nguyen, Abraham V., Figueiredo, Camila C., Foubert, Philippe, Schmid, Michael C., Pink, Melissa, Winkler, David G., Rausch, Matthew, Palombella, Vito J., Kutok, Jeffery, McGovern, Karen, Frazer, Kelly A., Wu, Xuefeng, Karin, Michael, Sasik, Roman, Cohen, Ezra E. W., Varner, Judith A.

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Sclerostin Inhibition of Wnt-3a-induced C3H10T1/2 Cell Differentiation Is Indirect and Mediated by Bone Morphogenetic Proteins von Winkler, David G., Sutherland, May S. Kung, Ojala, Ethan, Turcott, Eileen, Geoghegan, James C., Shpektor, Diana, Skonier, John E., Yu, Changpu, Latham, John A.

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Unique regulation of SOST, the sclerosteosis gene, by BMPs and steroid hormones in human osteoblasts von Sutherland, May Kung, Geoghegan, James C, Yu, Changpu, Winkler, David G, Latham, John A

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Osteocyte control of bone formation via sclerostin, a novel BMP antagonist von Winkler, David G., Sutherland, May Kung, Geoghegan, James C., Yu, Changpu, Hayes, Trenton, Skonier, John E., Shpektor, Diana, Jonas, Mechtild, Kovacevich, Brian R., Staehling-Hampton, Karen, Appleby, Mark, Brunkow, Mary E., Latham, John A.

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Noggin and Sclerostin Bone Morphogenetic Protein Antagonists Form a Mutually Inhibitory Complex von Winkler, David G, Yu, Changpu, Geoghegan, James C, Ojala, Ethan W, Skonier, John E, Shpektor, Diana, Sutherland, May K, Latham, John A

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Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)‑γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate von Evans, Catherine A, Liu, Tao, Lescarbeau, André, Nair, Somarajan J, Grenier, Louis, Pradeilles, Johan A, Glenadel, Quentin, Tibbitts, Thomas, Rowley, Ann M, DiNitto, Jonathan P, Brophy, Erin E, O’Hearn, Erin L, Ali, Janid A, Winkler, David G, Goldstein, Stanley I, O’Hearn, Patrick, Martin, Christian M, Hoyt, Jennifer G, Soglia, John R, Cheung, Culver, Pink, Melissa M, Proctor, Jennifer L, Palombella, Vito J, Tremblay, Martin R, Castro, Alfredo C

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Complement C3a, CpG oligos, and DNA/C3a complex stimulate IFN-α production in a receptor for advanced glycation end product-dependent manner von Ruan, Benfang Helen, Li, Xin, Winkler, Aaron R, Cunningham, Kristina M, Kuai, Jun, Greco, Rita M, Nocka, Karl H, Fitz, Lori J, Wright, Jill F, Pittman, Debra D, Tan, Xiang-Yang, Paulsen, Janet E, Lin, Lih Ling, Winkler, David G

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TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines von Kuai, Jun, Gregory, Bernard, Hill, Andrew, Pittman, Debra D., Feldman, Jeffrey L., Brown, Tom, Carito, Brenda, O’Toole, Margot, Ramsey, Renee, Adolfsson, Oskar, Shields, Kathleen M., Dower, Ken, Hall, J. Perry, Kurdi, Yahya, Beech, Jonathan T., Nanchahal, Jagdeep, Feldmann, Marc, Foxwell, Brian M., Brennan, Fionula M., Winkler, David G., Lin, Lih-Ling

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Corrigendum: PI3Kγ is a molecular switch that controls immune suppression von Kaneda, Megan M, Messer, Karen S, Ralainirina, Natacha, Li, Hongying, Leem, Christopher J, Gorjestani, Sara, Woo, Gyunghwi, Nguyen, Abraham V, Figueiredo, Camila C, Foubert, Philippe, Schmid, Michael C, Pink, Melissa, Winkler, David G, Rausch, Matthew, Palombella, Vito J, Kutok, Jeffery, McGovern, Karen, Frazer, Kelly A, Wu, Xuefeng, Karin, Michael, Sasik, Roman, Cohen, Ezra E W, Varner, Judith A

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Complex responses to a diverse environment von Collins, Mary, Winkler, David G, Lin, Lih-Ling

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PI3K-δ and PI3K-γ Inhibition by IPI-145 Abrogates Immune Responses and Suppresses Activity in Autoimmune and Inflammatory Disease Models von Winkler, David G., Faia, Kerrie L., DiNitto, Jonathan P., Ali, Janid A., White, Kerry F., Brophy, Erin E., Pink, Melissa M., Proctor, Jennifer L., Lussier, Jennifer, Martin, Christian M., Hoyt, Jennifer G., Tillotson, Bonnie, Murphy, Erin L., Lim, Alice R., Thomas, Brian D., MacDougall, John R., Ren, Pingda, Liu, Yi, Li, Lian-Sheng, Jessen, Katti A., Fritz, Christian C., Dunbar, Joi L., Porter, James R., Rommel, Christian, Palombella, Vito J., Changelian, Paul S., Kutok, Jeffery L.

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Identification of Residues in the Cysteine-rich Domain of Raf-1 That Control Ras Binding and Raf-1 Activity von Winkler, David G., Cutler, Richard E., Drugan, Jonelle K., Campbell, Sharon, Morrison, Deborah K., Cooper, Jonathan A.

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Phosphorylation of Ser-42 and Ser-59 in the N-terminal region of the tyrosine kinase p56(lck) von Winkler, David G, Park, Indal, Kim, TaeUe, Payne, Nicola S

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Corrigendum: PI3K is a molecular switch that controls immune suppression von Kaneda, Megan M, Messer, Karen S, Ralainirina, Natacha, Li, Hongying, Leem, Christopher J, Gorjestani, Sara, Woo, Gyunghwi, Nguyen, Abraham V, Figueiredo, Camila C, Foubert, Philippe, Schmid, Michael C, Pink, Melissa, Winkler, David G, Rausch, Matthew, Palombella, Vito J, Kutok, Jeffery, McGovern, Karen, Frazer, Kelly A, Wu, Xuefeng, Karin, Michael, Sasik, Roman, Cohen, Ezra E. W, Varner, Judith A

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Correction: Corrigendum: PI3Kγ is a molecular switch that controls immune suppression von Kaneda, Megan M., Messer, Karen S., Ralainirina, Natacha, Li, Hongying, Leem, Christopher J., Gorjestani, Sara, Woo, Gyunghwi, Nguyen, Abraham V., Figueiredo, Camila C., Foubert, Philippe, Schmid, Michael C., Pink, Melissa, Winkler, David G., Rausch, Matthew, Palombella, Vito J., Kutok, Jeffery, McGovern, Karen, Frazer, Kelly A., Wu, Xuefeng, Karin, Michael, Sasik, Roman, Cohen, Ezra E. W., Varner, Judith A.

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Erratum: Corrigendum: PI3Kγ is a molecular switch that controls immune suppression von Kaneda, Megan M., Messer, Karen S., Ralainirina, Natacha, Li, Hongying, Leem, Christopher J., Gorjestani, Sara, Woo, Gyunghwi, Nguyen, Abraham V., Figueiredo, Camila C., Foubert, Philippe, Schmid, Michael C., Pink, Melissa, Winkler, David G., Rausch, Matthew, Palombella, Vito J., Kutok, Jeffery, McGovern, Karen, Frazer, Kelly A., Wu, Xuefeng, Karin, Michael, Sasik, Roman, Cohen, Ezra E. W., Varner, Judith A.

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PI3K is a molecular switch that controls immune suppression von Kaneda, Megan M, Messer, Karen S, Ralainirina, Natacha, Li, Hongying, Leem, Christopher J, Gorjestani, Sara, Woo, Gyunghwi, Nguyen, Abraham V, Figueiredo, Camila C, Foubert, Philippe, Schmid, Michael C, Pink, Melissa, Winkler, David G, Rausch, Matthew, Palombella, Vito J, Kutok, Jeffery, McGovern, Karen, Frazer, Kelly A, Wu, Xuefeng, Karin, Michael, Sasik, Roman, Cohen, Ezra E. W, Varner, Judith A

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