The Cancer Stem Cell Marker Aldehyde Dehydrogenase Is Required to Maintain a Drug-Tolerant Tumor Cell Subpopulation von RAHA, Debasish, WILSON, Timothy R, JING PENG, PETERSON, David, PENG YUE, EVANGELISTA, Marie, WILSON, Catherine, MERCHANT, Mark, SETTLEMAN, Jeff

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Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors von Wilson, Timothy R., Fridlyand, Jane, Yan, Yibing, Penuel, Elicia, Burton, Luciana, Chan, Emily, Peng, Jing, Lin, Eva, Wang, Yulei, Sosman, Jeff, Ribas, Antoni, Li, Jiang, Moffat, John, Sutherlin, Daniel P., Koeppen, Hartmut, Merchant, Mark, Neve, Richard, Settleman, Jeff

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Heterogeneity and clinical significance of ESR1 mutations in ER-positive metastatic breast cancer patients receiving fulvestrant von Spoerke, Jill M., Gendreau, Steven, Walter, Kimberly, Qiu, Jiaheng, Wilson, Timothy R., Savage, Heidi, Aimi, Junko, Derynck, Mika K., Chen, Meng, Chan, Iris T., Amler, Lukas C., Hampton, Garret M., Johnston, Stephen, Krop, Ian, Schmid, Peter, Lackner, Mark R.

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Unicorns, Rhinoceroses and Chemical Bonds von Gribben, Jordan, Wilson, Timothy R, Eberhart, Mark E

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Neuregulin-1-Mediated Autocrine Signaling Underlies Sensitivity to HER2 Kinase Inhibitors in a Subset of Human Cancers von Wilson, Timothy R., Lee, Diana Y., Berry, Leanne, Shames, David S., Settleman, Jeff

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Neoadjuvant letrozole plus taselisib versus letrozole plus placebo in postmenopausal women with oestrogen receptor-positive, HER2-negative, early-stage breast cancer (LORELEI): a m... von Saura, Cristina, MD, Hlauschek, Dominik, MS, Oliveira, Mafalda, MD, Zardavas, Dimitrios, MD, Jallitsch-Halper, Anita, PhD, de la Peña, Lorena, PhD, Nuciforo, Paolo, MD, Ballestrero, Alberto, MD, Dubsky, Peter, MD, Lombard, Janine M, MD, Vuylsteke, Peter, MD, Castaneda, Carlos A, MD, Colleoni, Marco, MD, Santos Borges, Giuliano, MD, Ciruelos, Eva, MD, Fornier, Monica, MD, Boer, Katalin, MD, Bardia, Aditya, MD, Wilson, Timothy R, PhD, Stout, Thomas J, MD, Hsu, Jerry Y, MD, Shi, Yi, PhD, Piccart, Martine, Prof, Gnant, Michael, Prof, Baselga, José, MD, de Azambuja, Evandro, MD

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Principles Determining the Structure of Transition Metals von Riddle, Samuel K., Wilson, Timothy R., Rajivmoorthy, Malavikha, Eberhart, Mark E.

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NTRK gene fusions are detected in both secretory and non‐secretory breast cancers von Maund, Sophia L., Sokol, Ethan S., Ang Houle, Armande, Ross, Jeffrey S., Wilson, Timothy R.

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Multiple PIK3CA mutation clonality correlates with outcomes in taselisib + fulvestrant-treated ER+/HER2-, PIK3CA-mutated breast cancers von Hutchinson, Katherine E, Chen, Jessica W, Savage, Heidi M, Stout, Thomas J, Schimmoller, Frauke, Cortés, Javier, Dent, Susan, Harbeck, Nadia, Jacot, William, Krop, Ian, Trabucco, Sally E, Sivakumar, Smruthy, Sokol, Ethan S, Wilson, Timothy R

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Growth‐rate model predicts in vivo tumor response from in vitro data von Diegmiller, Rocky, Salphati, Laurent, Alicke, Bruno, Wilson, Timothy R., Stout, Thomas J., Hafner, Marc

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Pre‐ and post‐treatment blood‐based genomic landscape of patients with ROS1 or NTRK fusion‐positive solid tumours treated with entrectinib von Dziadziuszko, Rafal, Hung, Tiffany, Wang, Kun, Choeurng, Voleak, Drilon, Alexander, Doebele, Robert C., Barlesi, Fabrice, Wu, Charlie, Dennis, Lucas, Skoletsky, Joel, Woodhouse, Ryan, Li, Meijuan, Chang, Ching‐Wei, Simmons, Brian, Riehl, Todd, Wilson, Timothy R.

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ER+, HER2- advanced breast cancer treated with taselisib and fulvestrant: genomic landscape and associated clinical outcomes von Chen, Jessica W, Jacot, William, Cortés, Javier, Krop, Ian E, Dent, Susan, Harbeck, Nadia, De Laurentiis, Michelino, Diéras, Véronique, Im, Young-Hyuck, Stout, Thomas J, Schimmoller, Frauke, Savage, Heidi M, Hutchinson, Katherine E, Wilson, Timothy R

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High heregulin expression is associated with activated HER3 and may define an actionable biomarker in patients with squamous cell carcinomas of the head and neck von Shames, David S, Carbon, Juliet, Walter, Kim, Jubb, Adrian M, Kozlowski, Cleopatra, Januario, Tom, Do, An, AnDo, Fu, Ling, Xiao, Yuanyuan, Raja, Rajiv, Jiang, Brittany, Malekafzali, Ashi, Stern, Howard, Settleman, Jeff, Wilson, Timothy R, Hampton, Garret M, Yauch, Robert L, Pirzkall, Andrea, Amler, Lukas C

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MET gene amplification is a mechanism of resistance to entrectinib in ROS1+ NSCLC von Tyler, Logan C., Le, Anh T., Chen, Nan, Nijmeh, Hala, Bao, Liming, Wilson, Timothy R., Chen, David, Simmons, Brian, Turner, Kristen M., Perusse, Dean, Kasibhatla, Shailaja, Christiansen, Jason, Dudek, Arkadiusz Z., Doebele, Robert C.

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Ancestry-associated co-alteration landscape of KRAS and EGFR-altered non-squamous NSCLC von Sisoudiya, Saumya D., Houle, Armande Ang, Fernando, Tharu, Wilson, Timothy R., Schutzman, Jennifer L., Lee, Jessica, Schrock, Alexa, Sokol, Ethan S., Sivakumar, Smruthy, Shi, Zhen, Pathria, Gaurav

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Targeted biomarker profiling of matched primary and metastatic estrogen receptor positive breast cancers von Schleifman, Erica B, Desai, Rupal, Spoerke, Jill M, Xiao, Yuanyuan, Wong, Cheryl, Abbas, Ilma, O'Brien, Carol, Patel, Rajesh, Sumiyoshi, Teiko, Fu, Ling, Tam, Rachel N, Koeppen, Hartmut, Wilson, Timothy R, Raja, Rajiv, Hampton, Garret M, Lackner, Mark R

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Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1–2 trials von Doebele, Robert C, Drilon, Alexander, Paz-Ares, Luis, Siena, Salvatore, Shaw, Alice T, Farago, Anna F, Blakely, Collin M, Seto, Takashi, Cho, Byung Chul, Tosi, Diego, Besse, Benjamin, Chawla, Sant P, Bazhenova, Lyudmila, Krauss, John C, Chae, Young Kwang, Barve, Minal, Garrido-Laguna, Ignacio, Liu, Stephen V, Conkling, Paul, John, Thomas, Fakih, Marwan, Sigal, Darren, Loong, Herbert H, Buchschacher, Gary L, Garrido, Pilar, Nieva, Jorge, Steuer, Conor, Overbeck, Tobias R, Bowles, Daniel W, Fox, Elizabeth, Riehl, Todd, Chow-Maneval, Edna, Simmons, Brian, Cui, Na, Johnson, Ann, Eng, Susan, Wilson, Timothy R, Demetri, George D

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Measurement of Health-Related Quality of Life in the Early Follow-Up of Colon and Rectal Cancer von Wilson, Timothy R, Alexander, David J, Kind, P

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Chemotherapy and TRAIL-mediated colon cancer cell death: the roles of p53, TRAIL receptors, and c-FLIP von Galligan, Leeona, Longley, Daniel B, McEwan, Miranda, Wilson, Timothy R, McLaughlin, Kirsty, Johnston, Patrick G

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Updated Integrated Analysis of the Efficacy and Safety of Entrectinib in Patients With NTRK Fusion-Positive Solid Tumors von Demetri, George D, De Braud, Filippo, Drilon, Alexander, Siena, Salvatore, Patel, Manish R, Cho, Byoung Chul, Liu, Stephen V, Ahn, Myung-Ju, Chiu, Chao-Hua, Lin, Jessica J, Goto, Koichi, Lee, Jeeyun, Bazhenova, Lyudmila, John, Thomas, Fakih, Marwan, Chawla, Sant P, Dziadziuszko, Rafal, Seto, Takashi, Heinzmann, Sebastian, Pitcher, Bethany, Chen, David, Wilson, Timothy R, Rolfo, Christian

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