Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway von Jansz, Natasha, Nesterova, Tatyana, Keniry, Andrew, Iminitoff, Megan, Hickey, Peter F., Pintacuda, Greta, Masui, Osamu, Kobelke, Simon, Geoghegan, Niall, Breslin, Kelsey A., Willson, Tracy A., Rogers, Kelly, Kay, Graham F., Fox, Archa H., Koseki, Haruhiko, Brockdorff, Neil, Murphy, James M., Blewitt, Marnie E.

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The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells von Loughran, Stephen J, Kruse, Elizabeth A, Hacking, Douglas F, de Graaf, Carolyn A, Hyland, Craig D, Willson, Tracy A, Henley, Katya J, Ellis, Sarah, Voss, Anne K, Metcalf, Donald, Hilton, Douglas J, Alexander, Warren S, Kile, Benjamin T

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ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification von Taoudi, Samir, Bee, Thomas, Hilton, Adrienne, Knezevic, Kathy, Scott, Julie, Willson, Tracy A, Collin, Caitlin, Thomas, Tim, Voss, Anne K, Kile, Benjamin T, Alexander, Warren S, Pimanda, John E, Hilton, Douglas J

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Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid-binding residues von Chen, Kelan, Birkinshaw, Richard W, Gurzau, Alexandra D, Wanigasuriya, Iromi, Wang, Ruoyun, Iminitoff, Megan, Sandow, Jarrod J, Young, Samuel N, Hennessy, Patrick J, Willson, Tracy A, Heckmann, Denise A, Webb, Andrew I, Blewitt, Marnie E, Czabotar, Peter E, Murphy, James M

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Suppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regulation of JAK1 and interaction with the adaptor protein Shc-1 von Linossi, Edmond M, Chandrashekaran, Indu R, Kolesnik, Tatiana B, Murphy, James M, Webb, Andrew I, Willson, Tracy A, Kedzierski, Lukasz, Bullock, Alex N, Babon, Jeffrey J, Norton, Raymond S, Nicola, Nicos A, Nicholson, Sandra E

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SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation von Kuang, Zhihe, Lewis, Rowena S, Curtis, Joan M, Zhan, Yifan, Saunders, Bernadette M, Babon, Jeffrey J, Kolesnik, Tatiana B, Low, Andrew, Masters, Seth L, Willson, Tracy A, Kedzierski, Lukasz, Yao, Shenggen, Handman, Emanuela, Norton, Raymond S, Nicholson, Sandra E

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Regulation of hematopoietic stem cells by their mature progeny von de Graaf, Carolyn A., Kauppi, Maria, Baldwin, Tracey, Hyland, Craig D., Metcalf, Donald, Willson, Tracy A., Carpinelli, Marina R., Smyth, Gordon K., Alexander, Warren S., Hilton, Douglas J.

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Leptin can Induce Proliferation, Differentiation, and Functional Activation of Hemopoietic Cells von Gainsford, Timothy, Willson, Tracy A., Metcalf, Donald, Handman, Emanuela, McFarlane, Clare, Ng, Ashley, Nicola, Nicos A., Alexander, Warren S., Hilton, Douglas J.

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Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia von Kile, Benjamin T., Panopoulos, Athanasia D., Stirzaker, Roslynn A., Hacking, Douglas F., Tahtamouni, Lubna H., Willson, Tracy A., Mielke, Lisa A., Henley, Katya J., Zhang, Jian-Guo, Wicks, Ian P., Stevenson, William S., Nurden, Paquita, Watowich, Stephanie S., Justice, Monica J.

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Suppressor Screen in Mpl-/- Mice: c-Myb Mutation Causes Supraphysiological Production of Platelets in the Absence of Thrombopoietin Signaling von Carpinelli, Marina R., Hilton, Douglas J., Metcalf, Donald, Antonchuk, Jennifer L., Hyland, Craig D., Mifsud, Sandra L., Di Rago, Ladina, Hilton, Adrienne A., Willson, Tracy A., Roberts, Andrew W., Ramsay, Robert G., Nicola, Nicos A., Alexander, Warren S.

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ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity von Young, Matthew D., Willson, Tracy A., Wakefield, Matthew J., Trounson, Evelyn, Hilton, Douglas J., Blewitt, Marnie E., Oshlack, Alicia, Majewski, Ian J.

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The Conserved SOCS Box Motif in Suppressors of Cytokine Signaling Binds to Elongins B and C and May Couple Bound Proteins to Proteasomal Degradation von Zhang, Jian-Guo, Farley, Alison, Nicholson, Sandra E., Willson, Tracy A., Zugaro, Lisa M., Simpson, Richard J., Moritz, Robert L., Cary, Dale, Richardson, Rachael, Hausmann, George, Kile, Benjamin J., Stephen B. H. Kent, Alexander, Warren S., Metcalf, Donald, Hilton, Douglas J., Nicola, Nicos A., Baca, Manuel

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SPRY Domain-Containing SOCS Box Protein 2: Crystal Structure and Residues Critical for Protein Binding von Kuang, Zhihe, Yao, Shenggen, Xu, Yibin, Lewis, Rowena S., Low, Andrew, Masters, Seth L., Willson, Tracy A., Kolesnik, Tatiana B., Nicholson, Sandra E., Garrett, Thomas J.P., Norton, Raymond S.

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Biological Evidence That SOCS-2 Can Act Either as an Enhancer or Suppressor of Growth Hormone Signaling von Greenhalgh, Christopher J, Metcalf, Donald, Thaus, Anne L, Corbin, Jason E, Uren, Rachel, Morgan, Phillip O, Fabri, Louis J, Zhang, Jian-Guo, Martin, Helene M, Willson, Tracy A, Billestrup, Nils, Nicola, Nicos A, Baca, Manuel, Alexander, Warren S, Hilton, Douglas J

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Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice von Stevenson, William S., Hyland, Craig D., Zhang, Jian-Guo, Morgan, Phillip O., Willson, Tracy A., Gill, Anthony, Hilton, Adrienne A., Viney, Elizabeth M., Bahlo, Melanie, Masters, Seth L., Hennebry, Sarah, Richardson, Samantha J., Nicola, Nicos A., Metcalf, Donald, Hilton, Douglas J., Roberts, Andrew W., Alexander, Warren S.

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Differential in vivo roles of Mpl cytoplasmic tyrosine residues in murine hematopoiesis and myeloproliferative disease von Behrens, Kira, Kauppi, Maria, Viney, Elizabeth M., Kueh, Andrew J., Hyland, Craig D., Willson, Tracy A., Salleh, Liam, de Graaf, Carolyn A., Babon, Jeffrey J., Herold, Marco J., Nicola, Nicos A., Alexander, Warren S.

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Suppressor of Cytokine Signaling (SOCS)-5 Is a Potential Negative Regulator of Epidermal Growth Factor Signaling von Nicholson, Sandra E., Metcalf, Donald, Sprigg, Naomi S., Columbus, Ruth, Walker, Francesca, Silva, Anabel, Cary, Dale, Willson, Tracy A., Zhang, Jian-Guo, Hilton, Douglas J., Alexander, Warren S., Nicola, Nicos A.

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SMCHD1's ubiquitin-like domain is required for N-terminal dimerization and chromatin localization von Gurzau, Alexandra D., Horne, Christopher R., Mok, Yee-Foong, Iminitoff, Megan, Willson, Tracy A., Young, Samuel N., Blewitt, Marnie E., Murphy, James M.

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Development of Hydrocephalus in Mice Lacking SOCS7 von Krebs, Danielle L., Metcalf, Donald, Merson, Tobias D., Voss, Anne K., Thomas, Tim, Zhang, Jian-Guo, Rakar, Steven, O'Bryan, Moira K., Wilson, Tracy A., Viney, Elizabeth M., Mielke, Lisa A., Nicola, Nicos A., Hilton, Douglas J., Alexander, Warren S.

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Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome von Witkowski, Matthew T, Hu, Yifang, Roberts, Kathryn G, Boer, Judith M, McKenzie, Mark D, Liu, Grace J, Le Grice, Oliver D, Tremblay, Cedric S, Ghisi, Margherita, Willson, Tracy A, Horstmann, Martin A, Aifantis, Iannis, Cimmino, Luisa, Frietze, Seth, den Boer, Monique L, Mullighan, Charles G, Smyth, Gordon K, Dickins, Ross A

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