Genome-wide transcription and the implications for genomic organization von Kapranov, Philipp, Willingham, Aarron T., Gingeras, Thomas R.

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RNA Maps Reveal New RNA Classes and a Possible Function for Pervasive Transcription von Kapranov, Philipp, Cheng, Jill, Dike, Sujit, Nix, David A., Duttagupta, Radharani, Willingham, Aarron T., Stadler, Peter F., Hertel, Jana, Hackermüller, Jörg, Hofacker, Ivo L., Bell, Ian, Cheung, Evelyn, Drenkow, Jorg, Dumais, Erica, Patel, Sandeep, Helt, Gregg, Ganesh, Madhavan, Ghosh, Srinka, Piccolboni, Antonio, Sementchenko, Victor, Tammana, Hari, Gingeras, Thomas R.

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Post-transcriptional processing generates a diversity of 5′-modified long and short RNAs von Fejes-Toth, Katalin, Sotirova, Vihra, Sachidanandam, Ravi, Assaf, Gordon, Hannon, Gregory J, Kapranov, Philipp, Foissac, Sylvain, Willingham, Aarron T, Duttagupta, Radha, Dumais, Erica, Gingeras, Thomas R

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TUF Love for “Junk” DNA von Willingham, Aarron T., Gingeras, Thomas R.

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Characterization of MK-4166, a Clinical Agonistic Antibody That Targets Human GITR and Inhibits the Generation and Suppressive Effects of T Regulatory Cells von Sukumar, Selvakumar, Wilson, Douglas C, Yu, Ying, Wong, Jerelyn, Naravula, Saraswathi, Ermakov, Grigori, Riener, Romina, Bhagwat, Bhagyashree, Necheva, Antoaneta S, Grein, Jeff, Churakova, Tatyana, Mangadu, Ruban, Georgiev, Peter, Manfra, Denise, Pinheiro, Elaine M, Sriram, Venkataraman, Bailey, Wendy J, Herzyk, Danuta, McClanahan, Terrill K, Willingham, Aarron, Beebe, Amy M, Sadekova, Svetlana

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Single-stranded microRNA mimics von Chorn, Guillaume, Klein-McDowell, Molly, Zhao, Lihong, Saunders, Matthew A, Flanagan, W Michael, Willingham, Aarron T, Lim, Lee P

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mRNA knockdown by single strand RNA is improved by chemical modifications von Haringsma, Henry J, Li, Jenny J, Soriano, Ferdie, Kenski, Denise M, Flanagan, W Michael, Willingham, Aarron T

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A Drosophila Mechanosensory Transduction Channel von Walker, Richard G., Willingham, Aarron T., Zuker, Charles S.

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siRNA-optimized Modifications for Enhanced In Vivo Activity von Kenski, Denise M, Butora, Gabor, Willingham, Aarron T, Cooper, Abby J, Fu, Wenlang, Qi, Ning, Soriano, Ferdie, Davies, Ian W, Flanagan, W Michael

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Nucleobase and Ribose Modifications Control Immunostimulation by a MicroRNA-122-mimetic RNA von Peacock, Hayden, Fucini, Raymond V, Jayalath, Prasanna, Ibarra-Soza, José M, Haringsma, Henry J, Flanagan, W. Michael, Willingham, Aarron, Beal, Peter A

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Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5'-terminal phosphorylation both in vitro and in vivo von Kenski, Denise M, Cooper, Abby J, Li, Jenny J, Willingham, Aarron T, Haringsma, Henry J, Young, Tracy A, Kuklin, Nelly A, Jones, Jeffrey J, Cancilla, Mark T, McMasters, Daniel R, Mathur, Melina, Sachs, Alan B, Flanagan, W. Michael

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RNAi and HTS: exploring cancer by systematic loss-of-function von Willingham, Aarron T, Deveraux, Quinn L, Hampton, Garret M, Aza-Blanc, Pedro

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Adenosine Modification May Be Preferred for Reducing siRNA Immune Stimulation von Fucini, Raymond V., Haringsma, Henry J., Deng, Patricia, Flanagan, W. Michael, Willingham, Aarron T.

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Engineering Oncolytic Coxsackievirus A21 with Small Transgenes and Enabling Cell-Mediated Virus Delivery by Integrating Viral cDNA into the Genome von Sam, Miranda, Selman, Mohammed, Zhao, Weilong, Jung, Jiwon, Willingham, Aarron, Phan, Uyen, Starling, Gary C, Gao, Qinshan

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In Vivo Activity and Duration of Short Interfering RNAs Containing a Synthetic 5′-Phosphate von Kenski, Denise M., Willingham, Aarron T., Haringsma, Henry J., Li, Jenny J., Flanagan, W. Michael

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Investigating combination benefit of PD1 and LAG3 co-blockade using an engineered cellular bioassay von Bhagwat, Bhagyashree, de Waal Malefyt, Rene, Willingham, Aarron

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Establishment of engineered cell-based assays mediating LAG3 and PD1 immune suppression enables potency measurement of blocking antibodies and assessment of signal transduction von Bhagwat, Bhagyashree, Cherwinski, Holly, Sathe, Manjiri, Seghezzi, Wolfgang, McClanahan, Terrill K., de Waal Malefyt, Rene, Willingham, Aarron

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The developmental transcriptome of Drosophila melanogaster von Graveley, Brenton R., Brooks, Angela N., Carlson, Joseph W., Duff, Michael O., Landolin, Jane M., Yang, Li, Artieri, Carlo G., van Baren, Marijke J., Boley, Nathan, Booth, Benjamin W., Brown, James B., Cherbas, Lucy, Davis, Carrie A., Dobin, Alex, Li, Renhua, Lin, Wei, Malone, John H., Mattiuzzo, Nicolas R., Miller, David, Sturgill, David, Tuch, Brian B., Zaleski, Chris, Zhang, Dayu, Blanchette, Marco, Dudoit, Sandrine, Eads, Brian, Green, Richard E., Hammonds, Ann, Jiang, Lichun, Kapranov, Phil, Langton, Laura, Perrimon, Norbert, Sandler, Jeremy E., Wan, Kenneth H., Willingham, Aarron, Zhang, Yu, Zou, Yi, Andrews, Justen, Bickel, Peter J., Brenner, Steven E., Brent, Michael R., Cherbas, Peter, Gingeras, Thomas R., Hoskins, Roger A., Kaufman, Thomas C., Oliver, Brian, Celniker, Susan E.

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Site-Specific Antibody Conjugation Using Modified Bisected N‑Glycans: Method Development and Potential toward Tunable Effector Function von Hsu, Yen-Pang, Nourzaie, Omar, Tocher, Ariel E., Nerella, Kavitha, Ermakov, Grigori, Jung, Jiwon, Fowler, Alexandra, Wu, Peidong, Ayesa, Umme, Willingham, Aarron, Beaumont, Maribel, Ingale, Sampat

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Discovery and Evaluation of TLR-Targeted Immune Agonists von Chernyak, Natalia, Bhagwat, Bhagyashree, Naravula, Saraswathi, Chen, Ying, Solban, Nicolas, Zhang, Fan, Kofman, Esther, Raoufi, Fahimeh, Dang, Xibei, Bao, Jianming, Tomazela, Daniela, Baily, Marc, Geierstanger, Bernhard, Flygare, John A., Han, Jin-Hwan, Willingham, Aarron, Seganish, W. Michael

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