Identification of novel genetic susceptibility loci for thoracic and abdominal aortic aneurysms via genome-wide association study using the UK Biobank Cohort von Ashvetiya, Tamara, Fan, Sherry X., Chen, Yi-Ju, Williams, Charles H., O'Connell, Jeffery R., Perry, James A., Hong, Charles C.

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Identifying genetic variants associated with the ICD10 (International Classification of Diseases10)-based diagnosis of cerebrovascular disease using a large-scale biomedical databa... von Alkhalfan, Fahad, Gyftopoulos, Alex, Chen, Yi-Ju, Williams, Charles H, Perry, James A, Hong, Charles C

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Inhibition of GPR68 kills glioblastoma in zebrafish xenograft models von Neitzel, Leif R, Fuller, Daniela T, Williams, Charles H, Hong, Charles C

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GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment von Williams, Charles H, Neitzel, Leif R, Cornell, Jessica, Rea, Samantha, Mills, Ian, Silver, Maya S, Ahmad, Jovanni D, Birukov, Konstantin G, Birukova, Anna, Brem, Henry, Tyler, Betty, Bar, Eli E, Hong, Charles C

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Twists in Catalysis: Alternating Conformations of Escherichia coli Thioredoxin Reductase von Lennon, Brett W., Williams, Charles H., Ludwig, Martha L.

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GPR68 Inhibition with a Novel Group of Ogremorphin Inhibitors Upregulate Endothelial Barrier Function and Protect Against Bacterial Pathogens or Acidosis‐induced Inflammation in Lu... von Karki, Pratap, Ke, Yunbo, Williams, Charles H., Hong, Charles C., Birukov, Konstantin G., Birukova, Anna A.

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BMPing Up Healing Capacity with FKBP12 Ligand von Williams, Charles H., Hong, Charles C.

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Assessment of the therapeutic efficacy of artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in northern KwaZulu-Natal: an observational cohort... von Vaughan-Williams, Charles H, Raman, Jaishree, Raswiswi, Eric, Immelman, Etienne, Reichel, Holger, Gate, Kelly, Knight, Steve

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Hypoplastic Left Heart Syndrome Sequencing Reveals a Novel NOTCH1 Mutation in a Family with Single Ventricle Defects von Durbin, Matthew D., Cadar, Adrian G., Williams, Charles H., Guo, Yan, Bichell, David P., Su, Yan Ru, Hong, Charles C.

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The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of t... von Arscott, L D, Gromer, S, Schirmer, R H, Becker, K, Williams, Jr, C H

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Studies of an active site mutant of the selenoprotein thioredoxin reductase: The Ser-Cys-Cys-Ser motif of the insect orthologue is not sufficient to replace the Cys-Sec dyad in the... von Johansson, Linda, Arscott, L. David, Ballou, David P., Williams, Charles H., Arnér, Elias S.J.

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High Content Screening for Modulators of Cardiovascular or Global Developmental Pathways in Zebrafish von Williams, Charles H., Hong, Charles C.

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Acid−Base Catalysis in the Mechanism of Thioredoxin Reductase from Drosophila melanogaster von Huang, Hsin-Hung, Arscott, L. David, Ballou, David P, Williams, Charles H

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Mechanism-Based Inactivation of Thioredoxin Reductase from Plasmodium falciparum by Mannich Bases. Implication for Cytotoxicity von Davioud-Charvet, Elisabeth, McLeish, Michael J, Veine, Donna M, Giegel, David, Arscott, L. David, Andricopulo, Adriano D, Becker, Katja, Müller, Sylke, Schirmer, R. Heiner, Williams, Charles H, Kenyon, George L

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Treatment of Severe Acute Respiratory Distress Syndrome: A Final Report on a Phase I Study von Hardaway, Robert M., Harke, Henning, Tyroch, Alan H., Williams, Charles H., Vazquez, Yvonne, Krause, Gary F.

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A REVIEW: MALIGNANT HYPERTHERMIA‐A GENETIC DISEASE OF SODIUM CHANNEL FUNCTION von Williams, Charles H.

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Malignant Hyperthermia: A secondary factor, i.e., intense peripheral vasoconstriction, drives heat retention von Williams, Charles H

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Malignant hyperthermia: A runaway thermogenic futile cycle at the sodium channel level von Williams, Charles H.

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Large scale zebrafish-based in vivo small molecule screen von Hao, Jijun, Williams, Charles H, Webb, Morgan E, Hong, Charles C

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Role of Active Site Tyrosine Residues in Catalysis by Human Glutathione Reductase von Krauth-Siegel, R. Luise, Arscott, L. David, Schönleben-Janas, Annette, Schirmer, R. Heiner, Williams, Charles H

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