A spatially anchored transcriptomic atlas of the human kidney papilla identifies significant immune injury in patients with stone disease von Canela, Victor Hugo, Bowen, William S., Ferreira, Ricardo Melo, Syed, Farooq, Lingeman, James E., Sabo, Angela R., Barwinska, Daria, Winfree, Seth, Lake, Blue B., Cheng, Ying-Hua, Gaut, Joseph P., Ferkowicz, Michael, LaFavers, Kaice A., Zhang, Kun, Coe, Fredric L., Worcester, Elaine, Jain, Sanjay, Eadon, Michael T., Williams, James C., El-Achkar, Tarek M.

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Selective TRIF-dependent signaling by a synthetic toll-like receptor 4 agonist von Bowen, William S, Minns, Laurie A, Johnson, David A, Mitchell, Thomas C, Hutton, Melinda M, Evans, Jay T

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Local immunomodulation with Fas ligand-engineered biomaterials achieves allogeneic islet graft acceptance von Headen, Devon M., Woodward, Kyle B., Coronel, María M., Shrestha, Pradeep, Weaver, Jessica D., Zhao, Hong, Tan, Min, Hunckler, Michael D., Bowen, William S., Johnson, Christopher T., Shea, Lonnie, Yolcu, Esma S., García, Andrés J., Shirwan, Haval

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A Novel Form of 4-1BBL Prevents Cancer Development via Nonspecific Activation of CD4 + T and Natural Killer Cells von Barsoumian, Hampartsoum B, Batra, Lalit, Shrestha, Pradeep, Bowen, William S, Zhao, Hong, Egilmez, Nejat K, Gomez-Gutierrez, Jorge G, Yolcu, Esma S, Shirwan, Haval

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Two distinct phenotypes of calcium oxalate stone formers could imply different long-term risks for renal function von Williams, James C., Bowen, William S., Lingeman, James E., Rivera, Marcelino, Worcester, Elaine M., El-Achkar, Tarek M.

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Interaction of Thiostrepton and Elongation Factor-G with the Ribosomal Protein L11-binding Domain von Bowen, William S., Van Dyke, Natalya, Murgola, Emanuel J., Lodmell, J. Stephen, Hill, Walter E.

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Local immunomodulation Fas ligand-engineered biomaterials achieves allogeneic islet graft acceptance von Headen, Devon M, Woodward, Kyle B, Coronel, María M, Shrestha, Pradeep, Weaver, Jessica D, Zhao, Hong, Tan, Min, Hunckler, Michael D, Bowen, William S, Johnson, Christopher T, Shea, Lonnie, Yolcu, Esma S, García, Andrés J, Shirwan, Haval

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Characterization of TRIF selectivity in the AGP class of lipid A mimetics: Role of secondary lipid chains von Khalaf, Juhienah K., Bowen, William S., Bazin, Hélène G., Ryter, Kendal T., Livesay, Mark T., Ward, Jon R., Evans, Jay T., Johnson, David A.

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The ‘Ethereal’ nature of TLR4 agonism and antagonism in the AGP class of lipid A mimetics von Bazin, Hélène G., Murray, Tim J., Bowen, William S., Mozaffarian, Afsaneh, Fling, Steven P., Bess, Laura S., Livesay, Mark T., Arnold, Jeffrey S., Johnson, Craig L., Ryter, Kendal T., Cluff, Christopher W., Evans, Jay T., Johnson, David A.

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A Spatial Atlas of the Human Kidneys of Cell Types and Functional Tissue Units Identified in Highly Multiplexed Immunofluorescence Images: FR-OR57 von Winfree, Seth, Sabo, Angela R., Barwinska, Daria, Cheng, Ying-Hua, Bowen, William S., Ferkowicz, Michael J., Ferreira, Ricardo Melo, Kaushal, Madhurima, Gaut, Joseph, Eadon, Michael T., El-Achkar, Tarek M., Jain, Sanjay

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Transcriptomic Mapping of the Human Kidney Papilla Reveals Myeloid Immune Activation and Matrix Remodeling Pathways in Stone Disease: PO0526 von Canela, Victor Hugo, Bowen, William S., ferreira, Ricardo Melo, Lake, Blue, Zhang, Kun, Jain, Sanjay, Eadon, Michael T., Williams, James C., El-Achkar, Tarek M.

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Display of CD47 protein on pancreatic islet grafts improves engraftment following intraportal transplantation von Shrestha, Pradeep, Bowen, William S., Batra, Lalit, Tan, Min, Yolcu, Esma S., Shirwan, Haval

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CD47 Overcomes Early Loss of Pancreatic Islet Grafts Transplanted Intraportally von Shrestha, Pradeep, Bowen, William S, Batra, Lalit, Tan, Min, Yolcu, Esma S, Shirwan, Haval

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A Spatially Anchored Transcriptomic Atlas of the Human Kidney Papilla Identifies Significant Immune Injury and Matrix Remodeling in Stone Disease Patients: FR-OR09 von Sabo, Angela R., Canela, Victor Hugo, Bowen, William S., ferreira, Ricardo Melo, Barwinska, Daria, Winfree, Seth, Lake, Blue, Cheng, Ying-Hua, LaFavers, Kaice A., Zhang, Kun, Coe, Fredric L., Worcester, Elaine M., Jain, Sanjay, Eadon, Michael T., Williams, James C., El-Achkar, Tarek M.

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Abstract 4145: A novel form of 4-1BB agonist shows robust immune protection against various tumor types through CD4+ memory-like T and NK cell axis von Shirwan, Haval, Barsoumian, Hampartsoum B., Batra, Lalit, Shrestha, Pradeep, Bowen, William S., Zhao, Hong, Egilmez, Nejat K., Gomez-Gutierrez, Jorge G., Yolcu, Esma S.

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A novel agonist of CD137 immune checkpoint stimulator serves as a cancer immunoprevention agent with efficacy against various tumor types von Batra, Lalit, Barsoumian, Hampartsoum B., Shrestha, Pradeep, Hawthorne, Jenci L., Bowen, William S., Zhao, Hong, Egilmez, Nejat K., Gomez-Gutierrez, Jorge G., Shirwan, Haval, Yolcu, Esma S.

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A novel form of 4-1BBL prevents cancer development via non-specific activation of CD4+ T and Natural Killer cells von Barsoumian, Hampartsoum B., Batra, Lalit, Shrestha, Pradeep, Bowen, William S., Zhao, Hong, Egilmez, Nejat K., Gomez-Gutierrez, Jorge G., Yolcu, Esma S., Shirwan, Haval

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PD-L1-engineered pancreatic islet grafts overcome rejection in allogeneic recipients von Batra, Lalit, Shrestha, Pradeep, Yolcu, Esma S., Zhao, Hong, Bowen, William S., Woodward, Kyle B., Coronel, María M., Tan, Min, García, Andrés J., Shirwan, Haval

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The Transient Display of a Chimeric PD-L1 Protein on Pancreatic Islets Promotes Indefinite Survival in Allogeneic Recipients von Batra, Lalit, Shrestha, Pradeep, Yolcu, Esma S, Zhao, Hong, Bowen, William S, Woodward, Kyle B, Coronel, María M, Tan, Min, García, Andrés J, Shirwan, Haval

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SA-FasL-engineered PEG microgels as a novel means of modulating immune response to allogeneic islet grafts von Shirwan, Haval, Woodward, Kyle B., Headen, Devon M., Zhao, Hong, Shrestha, Pradeep, Tan, Min, Bowen, William S., Coronel, María M., Hunckler, Michael D., Weaver, Jessica D., Yolcu, Esma S., García, Andrés J.

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