Diversity in the origins of proteostasis networks — a driver for protein function in evolution von Powers, Evan T., Balch, William E.

Volltext

From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations von Veit, Gudio, Avramescu, Radu G, Chiang, Annette N, Houck, Scott A, Cai, Zhiwei, Peters, Kathryn W, Hong, Jeong S, Pollard, Harvey B, Guggino, William B, Balch, William E, Skach, William R, Cutting, Garry R, Frizzell, Raymond A, Sheppard, David N, Cyr, Douglas M, Sorscher, Eric J, Brodsky, Jeffrey L, Lukacs, Gergely L

Volltext

Adapting Proteostasis for Disease Intervention von Balch, William E, Morimoto, Richard I, Dillin, Andrew, Kelly, Jeffery W

Volltext

Biological and chemical approaches to diseases of proteostasis deficiency von Powers, Evan T, Morimoto, Richard I, Dillin, Andrew, Kelly, Jeffery W, Balch, William E

Volltext

Tracing genetic diversity captures the molecular basis of misfolding disease von Zhao, Pei, Wang, Chao, Sun, Shuhong, Wang, Xi, Balch, William E.

Volltext

COPII cage assembly factor Sec13 integrates information flow regulating endomembrane function in response to human variation von Anglès, Frédéric, Gupta, Vijay, Wang, Chao, Balch, William E.

Volltext

Functional amyloid--from bacteria to humans von Fowler, Douglas M, Koulov, Atanas V, Balch, William E, Kelly, Jeffery W

Volltext

Functional amyloid formation within mammalian tissue von Fowler, Douglas M, Koulov, Atanas V, Alory-Jost, Christelle, Marks, Michael S, Balch, William E, Kelly, Jeffery W

Volltext

Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells von Pipalia, Nina H., Subramanian, Kanagaraj, Mao, Shu, Ralph, Harold, Hutt, Darren M., Scott, Samantha M., Balch, William E., Maxfield, Frederick R.

Volltext

Modulation of the maladaptive stress response to manage diseases of protein folding von Roth, Daniela Martino, Hutt, Darren M, Tong, Jiansong, Bouchecareilh, Marion, Wang, Ning, Seeley, Theo, Dekkers, Johanna F, Beekman, Jeffrey M, Garza, Dan, Drew, Lawrence, Masliah, Eliezer, Morimoto, Richard I, Balch, William E

Volltext

Structural Basis for Cargo Regulation of COPII Coat Assembly von Stagg, Scott M., LaPointe, Paul, Razvi, Abbas, Gürkan, Cemal, Potter, Clinton S., Carragher, Bridget, Balch, William E.

Volltext

Quantitating the epigenetic transformation contributing to cholesterol homeostasis using Gaussian process von Wang, Chao, Scott, Samantha M., Subramanian, Kanagaraj, Loguercio, Salvatore, Zhao, Pei, Hutt, Darren M., Farhat, Nicole Y., Porter, Forbes D., Balch, William E.

Volltext

The Biological and Chemical Basis for Tissue-Selective Amyloid Disease von Sekijima, Yoshiki, Wiseman, R. Luke, Matteson, Jeanne, Hammarström, Per, Miller, Sean R., Sawkar, Anu R., Balch, William E., Kelly, Jeffery W.

Volltext

Hsp90 Cochaperone Aha1 Downregulation Rescues Misfolding of CFTR in Cystic Fibrosis von Wang, Xiaodong, Venable, John, LaPointe, Paul, Hutt, Darren M., Koulov, Atanas V., Coppinger, Judith, Gurkan, Cemal, Kellner, Wendy, Matteson, Jeanne, Plutner, Helen, Riordan, John R., Kelly, Jeffery W., Yates, John R., Balch, William E.

Volltext

A chaperone trap contributes to the onset of cystic fibrosis von Coppinger, Judith A, Hutt, Darren M, Razvi, Abbas, Koulov, Atanas V, Pankow, Sandra, Yates, 3rd, John R, Balch, William E

Volltext

NPC1/NPC2 function as a tag team duo to mobilize cholesterol von Subramanian, Kanagaraj, Balch, William E

Volltext

Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis von Hutt, Darren M, Herman, David, Rodrigues, Ana P C, Noel, Sabrina, Pilewski, Joseph M, Matteson, Jeanne, Hoch, Ben, Kellner, Wendy, Kelly, Jeffery W, Schmidt, Andre, Thomas, Philip J, Matsumura, Yoshihiro, Skach, William R, Gentzsch, Martina, Riordan, John R, Sorscher, Eric J, Okiyoneda, Tsukasa, Yates, John R, Lukacs, Gergely L, Frizzell, Raymond A, Manning, Gerard, Gottesfeld, Joel M, Balch, William E

Volltext

Quantitative Analysis of the Proteome Response to the Histone Deacetylase Inhibitor (HDACi) Vorinostat in Niemann-Pick Type C1 disease von Subramanian, Kanagaraj, Rauniyar, Navin, Lavalleé-Adam, Mathieu, Yates, John R., Balch, William E.

Volltext

Proteostatic Hotspots in Amyloid Fibrils Protect Us from Neurodegeneration von Singh, Jay Kumar, Balch, William E.

Volltext

Biological and structural basis for Aha1 regulation of Hsp90 ATPase activity in maintaining proteostasis in the human disease cystic fibrosis von Koulov, Atanas V, LaPointe, Paul, Lu, Bingwen, Razvi, Abbas, Coppinger, Judith, Dong, Meng-Qiu, Matteson, Jeanne, Laister, Rob, Arrowsmith, Cheryl, Yates, 3rd, John R, Balch, William E

Volltext