Activation of Benznidazole by Trypanosomal Type I Nitroreductases Results in Glyoxal Formation von HALL, Belinda S, WILKINSON, Shane R

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Trypanocidal drugs: mechanisms, resistance and new targets von Wilkinson, Shane R., Kelly, John M.

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mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes von Wilkinson, Shane R, Taylor, Martin C, Horn, David, Kelly, John M, Cheeseman, Ian

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Challenges in Chagas Disease Drug Development von Francisco, Amanda F, Jayawardhana, Shiromani, Olmo, Francisco, Lewis, Michael D, Wilkinson, Shane R, Taylor, Martin C, Kelly, John M

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Novel 3-Nitro-1H-1,2,4-triazole-Based Amides and Sulfonamides as Potential Antitrypanosomal Agents von Papadopoulou, Maria V, Bloomer, William D, Rosenzweig, Howard S, Chatelain, Eric, Kaiser, Marcel, Wilkinson, Shane R, McKenzie, Caroline, Ioset, Jean-Robert

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Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite von Piacenza, Lucía, Peluffo, Gonzalo, Alvarez, María Noel, Kelly, John M, Wilkinson, Shane R, Radi, Rafael

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Exploiting the Drug-Activating Properties of a Novel Trypanosomal Nitroreductase von HALL, Belinda S, XINGHUA WU, LONGQIN HU, WILKINSON, Shane R

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Targeting the Substrate Preference of a Type I Nitroreductase To Develop Antitrypanosomal Quinone-Based Prodrugs von HALL, Belinda S, MEREDITH, Emma Louise, WILKINSON, Shane R

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Evaluating 5-Nitrofurans as Trypanocidal Agents von BOT, Christopher, HALL, Belinda S, ALVAREZ, Guzman, DI MAIO, Rossanna, GONZALEZ, Mercedes, CERECETTO, Hugo, WILKINSON, Shane R

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The Trypanosoma cruzi vitamin C dependent peroxidase confers protection against oxidative stress but is not a determinant of virulence von Taylor, Martin C, Lewis, Michael D, Fortes Francisco, Amanda, Wilkinson, Shane R, Kelly, John M

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Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase overexpression von Piacenza, Lucía, Irigoín, Florencia, Alvarez, María Noel, Peluffo, Gonzalo, Taylor, Martin C, Kelly, John M, Wilkinson, Shane R, Radi, Rafael

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Nifurtimox Activation by Trypanosomal Type I Nitroreductases Generates Cytotoxic Nitrile Metabolites von Hall, Belinda S., Bot, Christopher, Wilkinson, Shane R.

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Preclinical Studies in Anti-Trypanosomatidae Drug Development von Perdomo, Cintya, Aguilera, Elena, Corvo, Ileana, Faral-Tello, Paula, Serna, Elva, Robello, Carlos, Wilkinson, Shane R., Yaluff, Gloria, Alvarez, Guzmán

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Validation of spermidine synthase as a drug target in African trypanosomes von Taylor, Martin C, Kaur, Harparkash, Blessington, Bernard, Kelly, John M, Wilkinson, Shane R

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Unraveling the antitrypanosomal mechanism of benznidazole and related 2‐nitroimidazoles: From prodrug activation to DNA damage von Dattani, Ambika, Drammeh, Isatou, Mahmood, Aishah, Rahman, Mahbubur, Szular, Joanna, Wilkinson, Shane R.

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Trypanocidal Activity of Aziridinyl Nitrobenzamide Prodrugs von BOT, Chris, HALL, Belinda S, BASHIR, Noosheen, TAYLOR, Martin C, HELSBY, Nuala A, WILKINSON, Shane R

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Substoichiometric Levels of Cu2+ Ions Accelerate the Kinetics of Fiber Formation and Promote Cell Toxicity of Amyloid-β from Alzheimer Disease von Sarell, Claire J., Wilkinson, Shane R., Viles, John H.

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Evaluating Aziridinyl Nitrobenzamide Compounds as Leishmanicidal Prodrugs von VOAK, Andrew A, SEIFERT, Karin, HELSBY, Nuala A, WILKINSON, Shane R

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Deciphering the interstrand crosslink DNA repair network expressed by Trypanosoma brucei von Dattani, Ambika, Wilkinson, Shane R.

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Dissecting the interstrand crosslink DNA repair system of Trypanosoma cruzi von Martinez, Monica Zavala, Olmo, Francisco, Taylor, Martin C., Caudron, Fabrice, Wilkinson, Shane R.

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