A highly selective, cell-permeable furin inhibitor BOS-318 rescues key features of cystic fibrosis airway disease von Douglas, Lisa E.J., Reihill, James A., Ho, Melisa W.Y., Axten, Jeffrey M., Campobasso, Nino, Schneck, Jessica L., Rendina, Alan R., Wilcoxen, Keith M., Martin, S. Lorraine

Volltext

In vivo anti-tumor activity of the PARP inhibitor niraparib in homologous recombination deficient and proficient ovarian carcinoma von AlHilli, Mariam M, Becker, Marc A, Weroha, S. John, Flatten, Karen S, Hurley, Rachel M, Harrell, Maria I, Oberg, Ann L, Maurer, Matt J, Hawthorne, Kieran M, Hou, Xiaonan, Harrington, Sean C, McKinstry, Sarah, Meng, X. Wei, Wilcoxen, Keith M, Kalli, Kimberly R, Swisher, Elizabeth M, Kaufmann, Scott H, Haluska, Paul

Volltext

Antibacterial agents based on the cyclic d,l -α-peptide architecture von Ghadiri, M. Reza, Fernandez-Lopez, Sara, Kim, Hui-Sun, Choi, Ellen C, Delgado, Mercedes, Granja, Juan R, Khasanov, Alisher, Kraehenbuehl, Karin, Long, Georgina, Weinberger, Dana A, Wilcoxen, Keith M

Volltext

Antiviral cyclic d, l-α-peptides: Targeting a general biochemical pathway in virus infections von Horne, W. Seth, Wiethoff, Christopher M., Cui, Chunli, Wilcoxen, Keith M., Amorin, Manuel, Ghadiri, M. Reza, Nemerow, Glen R.

Volltext

Design of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylamino-pyrazolo[1,5-a] pyrimidine (NBI 30775/r121919) and structure-activity relationships of a series of potent... von CHEN CHEN, WILCOXEN, Keith M, BOZIGIAN, Haig, GRIGORIADIS, Dimitri E, HUANG, Charles Q, XIE, Yun-Feng, MCCARTHY, James R, WEBB, Thomas R, ZHU, Yun-Fei, SAUNDERS, John, LIU, Xin-Jun, CHEN, Ta-Kung

Volltext

Biomimetic Catalysis of Intermodular Aminoacyl Transfer von Wilcoxen, Keith M, Leman, Luke J, Weinberger, Dana A, Huang, Zheng-Zheng, Ghadiri, M. Reza

Volltext

Functional and Mechanistic Analyses of Biomimetic Aminoacyl Transfer Reactions in de Novo Designed Coiled Coil Peptides via Rational Active Site Engineering von Leman, Luke J, Weinberger, Dana A, Huang, Zheng-Zheng, Wilcoxen, Keith M, Ghadiri, M. Reza

Volltext

Design and synthesis of 3-(2-pyridyl)pyrazolo[1,5-a]pyrimidines as potent CRF1 receptor antagonists von HUANG, Charles Q, WILCOXEN, Keith M, GRIGORIADIS, Dimitri E, MCCARTHY, James R, CHEN CHEN

Volltext

Optimization of 3-phenylpyrazolo[1,5-a]pyrimidines as potent corticotropin-releasing factor-1 antagonists with adequate lipophilicity and water solubility von CHEN CHEN, WILCOXEN, Keith M, HUANG, Charles Q, MCCARTHY, James R, CHEN, Takung, GRIGORIADIS, Dimitri E

Volltext

Synthesis and initial structure–Activity relationships of a novel series of imidazolo[1,2- a]pyrimid-5-ones as potent GnRH receptor antagonists von Wilcoxen, Keith M., Zhu, Yun-Fei, Connors, Patrick J., Saunders, John, Gross, Timothy D., Gao, Yinghong, Reinhart, Greg J., Struthers, R.Scott, Chen, Chen

Volltext

Design, synthesis and structure–Activity relationships of novel imidazolo[1,2- a]pyrimid-5-ones as potent GnRH receptor antagonists von Gross, Timothy D., Zhu, Yun-Fei, Saunders, John, Wilcoxen, Keith M., Gao, Yinghong, Connors, Patrick J., Guo, Zhiqiang, Struthers, R.Scott, Reinhart, Greg J., Chen, Chen

Volltext

N-aroyloxy-2-thiopyridones as efficient oxygen-radical generators: novel time-controlled DNA photocleaving reagents von Theodorakis, Emmanuel A., Wilcoxen, Keith M.

Volltext

correction: Antibacterial agents based on the cyclic d,l - α -peptide architecture von Fernandez-Lopez, Sara, Kim, Hui-Sun, Choi, Ellen C, Delgado, Mercedes, Granja, Juan R, Khasanov, Alisher, Kraehenbuehl, Karin, Long, Georgina, Weinberger, Dana A, Wilcoxen, Keith M, Ghadiri, M. Reza

Volltext

Abstract A258: The PARP inhibitor niraparib demonstrates synergy with chemotherapy in treatment of patient derived Ewing's sarcoma tumorGraft models von Wilcoxen, Keith M., Brooks, David G., Tiruchinapalli, Dhanrajan, Anderson, Nathan, Donaldson, Rodney, Nivens, McIver, Cook, Charlie, Khor, Tin, Lu, Bin, De Oliveira, Elizabeth, Hawley, Erin, Bruckheimer, Elizabeth

Volltext

Four-Atom-Linked Capped Porphyrins:  Synthesis and Characterization von Johnson, Martin R, Seok, Won K, Ma, Wuping, Slebodnick, Carla, Wilcoxen, Keith M, Ibers, James A

Volltext

Abstract 1795: Characterization of a novel series of potent, selective inhibitors of wild type and mutant/fusion anaplastic lymphoma kinase von Wilcoxen, Keith M., Brake, Rachael L., Saffran, Doug, Teffera, Yohannes, Choquette, Deborah, Whittington, Doug, Yu, Violeta, Romero, Karina, Bode, Christiane, Stellwagen, John, Potashman, Michelle, Emkey, Renee, Andrews, Paul, Drew, Allison E., Xu, Man, Szilvassy, Stephen, Al-Assad, Samer, Lewis, Richard T.

Volltext

Design of 2,5-Dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and Structure−Activity Relationships of a Series of Potent a... von Chen, Chen, Wilcoxen, Keith M, Huang, Charles Q, Xie, Yun-Feng, McCarthy, James R, Webb, Thomas R, Zhu, Yun-Fei, Saunders, John, Liu, Xin-Jun, Chen, Ta-Kung, Bozigian, Haig, Grigoriadis, Dimitri E

Volltext

Antiviral cyclic D,L-α-peptides : Targeting a general biochemical pathway in virus infections: Chemistry & Biology of Natural Products, Tetrahedron Prize for Creativity in Organic... von HOME, W. Seth, WIETHOFF, Christopher M, CHUNLI CUI, WILCOXEN, Keith M, AMORIN, Manuel, GHADIRI, M. Reza, NEMEROW, Glen R

Volltext

Design and synthesis of 3-(2-pyridyl)pyrazolo[1,5- a]pyrimidines as potent CRF 1 receptor antagonists von Huang, Charles Q, Wilcoxen, Keith M, Grigoriadis, Dimitri E, McCarthy, James R, Chen, Chen

Volltext

MODULATING CERTAIN TYROSINE KINASES von WILCOXEN KEITH M

Volltext bestellen