Development of a Lung Cancer Therapeutic Based on the Tumor Suppressor MicroRNA-34 von WIGGINS, Jason F, RUFFINO, Lynnsie, KELNAR, Kevin, OMOTOLA, Michael, PATRAWALA, Lubna, BROWN, David, BADER, Andreas G

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The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44 von Tang, Dean G, Liu, Can, Kelnar, Kevin, Liu, Bigang, Chen, Xin, Calhoun-Davis, Tammy, Li, Hangwen, Patrawala, Lubna, Yan, Hong, Jeter, Collene, Honorio, Sofia, Wiggins, Jason F, Bader, Andreas G, Fagin, Randy, Brown, David

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Systemic Delivery of Tumor Suppressor microRNA Mimics Using a Neutral Lipid Emulsion Inhibits Lung Tumors in Mice von Trang, Phong, Wiggins, Jason F, Daige, Christopher L, Cho, Chris, Omotola, Michael, Brown, David, Weidhaas, Joanne B, Bader, Andreas G, Slack, Frank J

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Systemic delivery of a miR34a mimic as a potential therapeutic for liver cancer von Daige, Christopher L, Wiggins, Jason F, Priddy, Leslie, Nelligan-Davis, Terri, Zhao, Jane, Brown, David

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The let-7 microRNA reduces tumor growth in mouse models of lung cancer von Esquela-Kerscher, Aurora, Trang, Phong, Wiggins, Jason F., Patrawala, Lubna, Cheng, Angie, Ford, Lance, Weidhaas, Joanne Barnes, Brown, David, Bader, Andreas G., Slack, Frank J.

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Bacillus anthracis Edema Toxin Causes Extensive Tissue Lesions and Rapid Lethality in Mice von Firoved, Aaron M., Miller, Georgina F., Moayeri, Mahtab, Kakkar, Rahul, Shen, Yuequan, Wiggins, Jason F., McNally, Elizabeth M., Tang, Wei-Jen, Leppla, Stephen H.

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Anthrax Protective Antigen Cleavage and Clearance from the Blood of Mice and Rats von Moayeri, Mahtab, Wiggins, Jason F, Leppla, Stephen H

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Arginase Therapy Combines Effectively with Immune Checkpoint Blockade or Agonist Anti-OX40 Immunotherapy to Control Tumor Growth von Badeaux, Mark D., Rolig, Annah S., Agnello, Giulia, Enzler, Danlee, Kasiewicz, Melissa J., Priddy, Leslie, Wiggins, Jason F., Muir, Alexander, Sullivan, Mark R., Van Cleef, Jessica, Daige, Christopher, Vander Heiden, Matthew G., Rajamanickam, Venkatesh, Wooldridge, James E., Redmond, William L., Rowlinson, Scott W.

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Anthrax Lethal Toxin Induces Ketotifen-Sensitive Intradermal Vascular Leakage in Certain Inbred Mice von Gozes, Yehoshua, Moayeri, Mahtab, Wiggins, Jason F, Leppla, Stephen H

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Dph3, a Small Protein Required for Diphthamide Biosynthesis, Is Essential in Mouse Development von Liu, Shihui, Wiggins, Jason F., Sreenath, Taduru, Kulkarni, Ashok B., Ward, Jerrold M., Leppla, Stephen H.

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Mouse Susceptibility to Anthrax Lethal Toxin Is Influenced by Genetic Factors in Addition to Those Controlling Macrophage Sensitivity von MOAYERI, Mahtab, MARTINEZ, Nathaniel W, WIGGINS, Jason, YOUNG, Howard A, LEPPLA, Stephen H

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Cisplatin Inhibition of Anthrax Lethal Toxin von MOAYERI, Mahtab, WIGGINS, Jason F, LINDEMAN, Robin E, LEPPLA, Stephen H

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Regression of murine lung tumors by the let-7 microRNA von Trang, P, Medina, P P, Wiggins, J F, Ruffino, L, Kelnar, K, Omotola, M, Homer, R, Brown, D, Bader, A G, Weidhaas, J B, Slack, F J

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Anthrax Edema Toxin Sensitizes DBA/2J Mice to Lethal Toxin von Firoved, Aaron M, Moayeri, Mahtab, Wiggins, Jason F, Shen, Yuequan, Tang, Wei-Jen, Leppla, Stephen H

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Endocrine Perturbation Increases Susceptibility of Mice to Anthrax Lethal Toxin von Moayeri, Mahtab, Webster, Jeanette I, Wiggins, Jason F, Leppla, Stephen H, Sternberg, Esther M

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Oxidized ATP Protection against Anthrax Lethal Toxin von Moayeri, Mahtab, Wickliffe, Katherine E, Wiggins, Jason F, Leppla, Stephen H

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High density magnetic recording on protein-derived nanoparticles von Hoinville, Jay, Bewick, Angus, Gleeson, David, Jones, Richard, Kasyutich, Oksana, Mayes, Eric, Nartowski, Artur, Warne, Barnaby, Wiggins, Jason, Wong, Kim

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eP258: Pre-analytical considerations are important in the pharmacological assessment of enzyme therapeutics von Thorneloe, Kevin, Daige, Christopher, Wiggins, Jason, Priddy, Leslie, Van Cleef, Jess, Ferrati, Silvia, Sloan, Leslie, Rowlinson, Scott

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Abstract 869: Depletion of blood arginine with pegzilarginase (AEB1102) in combination with anti-PD-L1 increases tumor infiltration by immune cells and enhances antitumor activity von Agnello, Giulia, Badeaux, Mark D., Enzler, Danlee, Priddy, Leslie, Wiggins, Jason F., Daige, Christopher L., Rowlinson, Scott W.

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MRX34, a liposomal miR-34 mimic and potential first-in-class microRNA therapeutic: activity in animal models of liver cancer von Daige, Chris, Priddy, Leslie, Wiggins, Jason, Nelligan-Davis, Terri, Enzler, Danlee, Vadnagara, Komal, Brown, David

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