Inhibition of Prolyl Hydroxylases Increases Erythropoietin Production in ESRD von BERNHARDT, Wanja M, WIESENER, Michael S, SCIGALLA, Paul, CHOU, James, SCHMIEDER, Roland E, GUNZLER, Volkmar, ECKARDT, Kai-Uwe

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Renal fibrosis is the common feature of autosomal dominant tubulointerstitial kidney diseases caused by mutations in mucin 1 or uromodulin von Ekici, Arif B., Hackenbeck, Thomas, Morinière, Vincent, Pannes, Andrea, Buettner, Maike, Uebe, Steffen, Janka, Rolf, Wiesener, Antje, Hermann, Ingo, Grupp, Sina, Hornberger, Martin, Huber, Tobias B., Isbel, Nikky, Mangos, George, McGinn, Stella, Soreth-Rieke, Daniela, Beck, Bodo B., Uder, Michael, Amann, Kerstin, Antignac, Corinne, Reis, André, Eckardt, Kai-Uwe, Wiesener, Michael S.

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cfNOMe - A single assay for comprehensive epigenetic analyses of cell-free DNA von Erger, Florian, Nörling, Deborah, Borchert, Domenica, Leenen, Esther, Habbig, Sandra, Wiesener, Michael S, Bartram, Malte P, Wenzel, Andrea, Becker, Christian, Toliat, Mohammad R, Nürnberg, Peter, Beck, Bodo B, Altmüller, Janine

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Mutations in mitochondrial DNA causing tubulointerstitial kidney disease von Connor, Thomas M, Hoer, Simon, Mallett, Andrew, Gale, Daniel P, Gomez-Duran, Aurora, Posse, Viktor, Antrobus, Robin, Moreno, Pablo, Sciacovelli, Marco, Frezza, Christian, Duff, Jennifer, Sheerin, Neil S, Sayer, John A, Ashcroft, Margaret, Wiesener, Michael S, Hudson, Gavin, Gustafsson, Claes M, Chinnery, Patrick F, Maxwell, Patrick H

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Depression, Anxiety, Resilience and Coping Pre and Post Kidney Transplantation - Initial Findings from the Psychiatric Impairments in Kidney Transplantation (PI-KT)-Study von Müller, Helge H, Englbrecht, Matthias, Wiesener, Michael S, Titze, Stephanie, Heller, Katharina, Groemer, Teja W, Schett, Georg, Eckardt, Kai-Uwe, Kornhuber, Johannes, Maler, Juan Manuel

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Biallelic Expression of Mucin-1 in Autosomal Dominant Tubulointerstitial Kidney Disease: Implications for Nongenetic Disease Recognition von Knaup, Karl X, Hackenbeck, Thomas, Popp, Bernt, Stoeckert, Johanna, Wenzel, Andrea, Büttner-Herold, Maike, Pfister, Frederick, Schueler, Markus, Seven, Didem, May, Annette M, Halbritter, Jan, Gröne, Hermann-Josef, Reis, André, Beck, Bodo B, Amann, Kerstin, Ekici, Arif B, Wiesener, Michael S

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Hypoxia-inducible protein 2 is a novel lipid droplet protein and a specific target gene of hypoxia-inducible factor-1 von Gimm, Tina, Wiese, Melanie, Teschemacher, Barbara, Deggerich, Anke, Schödel, Johannes, Knaup, Karl X, Hackenbeck, Thomas, Hellerbrand, Claus, Amann, Kerstin, Wiesener, Michael S, Höning, Stefan, Eckardt, Kai-Uwe, Warneck, Christina

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Hypoxia-inducible Transcription Factors Stabilization in the Thick Ascending Limb Protects against Ischemic Acute Kidney Injury von SCHLEY, Gunnar, KLANKE, Bernd, MAXWELL, Patrick H, WILLAM, Carsten, SCHÖDEL, Johannes, FORSTREUTER, Frauke, SHUKLA, Deepa, KURTZ, Armin, AMANN, Kerstin, WIESENER, Michael S, ROSEN, Seymour, ECKARDT, Kai-Uwe

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Hypoxia inhibits nephrogenesis through paracrine Vegfa despite the ability to enhance tubulogenesis von Schley, Gunnar, Scholz, Holger, Kraus, Andre, Hackenbeck, Thomas, Klanke, Bernd, Willam, Carsten, Wiesener, Michael S., Heinze, Eva, Burzlaff, Nicolai, Eckardt, Kai-Uwe, Buchholz, Bjoern

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Hypoxia, via stabilization of the hypoxia-inducible factor HIF-1α, is a direct and sufficient stimulus for brain-type natriuretic peptide induction von Weidemann, Alexander, Klanke, Bernd, Wagner, Michael, Volk, Tilmann, Willam, Carsten, Wiesener, Michael S., Eckardt, Kai-Uwe, Warnecke, Christina

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HIF Activation Protects From Acute Kidney Injury von WEIDEMANN, Alexander, BERNHARDT, Wanja M, WILLAM, Carsten, KLANKE, Bernd, DANIEL, Christoph, BUCHHOLZ, Björn, CAMPEAN, Valentina, AMANN, Kerstin, WARNECKE, Christina, WIESENER, Michael S, ECKARDT, Kai-Uwe

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Renal tubular HIF-2α expression requires VHL inactivation and causes fibrosis and cysts von Schietke, Ruth E, Hackenbeck, Thomas, Tran, Maxine, Günther, Regina, Klanke, Bernd, Warnecke, Christina L, Knaup, Karl X, Shukla, Deepa, Rosenberger, Christian, Koesters, Robert, Bachmann, Sebastian, Betz, Peter, Schley, Gunnar, Schödel, Johannes, Willam, Carsten, Winkler, Thomas, Amann, Kerstin, Eckardt, Kai-Uwe, Maxwell, Patrick, Wiesener, Michael S

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Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure von BERNHARDT, Wanja M, CAMPEAN, Valentina, WILLAM, Carsten, WIESENER, Michael S, ECKARDT, Kai-Uwe, KANY, Sarah, JÜRGENSEN, Jan-Steffen, WEIDEMANN, Alexander, WARNECKE, Christina, AREND, Michael, KLAUS, Stephen, GÜNZLER, Volkmar, AMANN, Kerstin

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Discordant Clinical Course of Vitamin-D-Hydroxylase (CYP24A1) Associated Hypercalcemia in Two Adult Brothers With Nephrocalcinosis von Jobst-Schwan, Tilman, Pannes, Andrea, Schlingmann, Karl Peter, Eckardt, Kai-Uwe, Beck, Bodo B., Wiesener, Michael S.

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Tumor suppressor activity and epigenetic inactivation of hepatocyte growth factor activator inhibitor type 2/SPINT2 in papillary and clear cell renal cell carcinoma von MORRIS, Mark R, GENTLE, Dean, LATIF, Farida, MAHER, Eamonn R, ABDULRAHMAN, Mahera, MAINA, Esther N, GUPTA, Kunal, BANKS, Rosamonde E, WIESENER, Michael S, KISHIDA, Takeshi, YAO, Masahiro, TEH, Bin

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Mutual Regulation of Hypoxia-Inducible Factor and Mammalian Target of Rapamycin as a Function of Oxygen Availability von Knaup, Karl X, Jozefowski, Katrin, Schmidt, Regina, Bernhardt, Wanja M, Weidemann, Alexander, Juergensen, Jan Steffen, Warnecke, Christina, Eckardt, Kai-Uwe, Wiesener, Michael S

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Mutation Analysis of Hypoxia-inducible Factors HIF1A and HIF2A in Renal Cell Carcinoma von Morris, Mark R, Hughes, David J, Tian, Ya-Min, Ricketts, Christopher J, Lau, Kah Weng, Gentle, Dean, Shuib, Salwati, Serrano-Fernandez, Pablo, Lubinski, Jan, Wiesener, Michael S, Pugh, Christopher W, Latif, Farida, Ratcliffe, Peter J, Maher, Eamonn R

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Biallelic ANKS6 mutations cause late-onset ciliopathy with chronic kidney disease through YAP dysregulation von Schwarz, Hannah, Popp, Bernt, Airik, Rannar, Torabi, Nasrin, Knaup, Karl X, Stoeckert, Johanna, Wiech, Thorsten, Amann, Kerstin, Reis, André, Schiffer, Mario, Wiesener, Michael S, Schueler, Markus

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Lysyl Oxidases LOX and LOXL2 Are Necessary and Sufficient to Repress E-cadherin in Hypoxia: INSIGHTS INTO CELLULAR TRANSFORMATION PROCESSES MEDIATED BY HIF-1 von Schietke, Ruth, Warnecke, Christina, Wacker, Ingrid, Schödel, Johannes, Mole, David R, Campean, Valentina, Amann, Kerstin, Goppelt-Struebe, Margarete, Behrens, Jürgen, Eckardt, Kai-Uwe, Wiesener, Michael S

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Mutations in PIK3C2A cause syndromic short stature, skeletal abnormalities, and cataracts associated with ciliary dysfunction von Tiosano, Dov, Baris, Hagit N, Chen, Anlu, Hitzert, Marrit M, Schueler, Markus, Gulluni, Federico, Wiesener, Antje, Bergua, Antonio, Mory, Adi, Copeland, Brett, Gleeson, Joseph G, Rump, Patrick, van Meer, Hester, Sival, Deborah A, Haucke, Volker, Kriwinsky, Josh, Knaup, Karl X, Reis, André, Hauer, Nadine N, Hirsch, Emilio, Roepman, Ronald, Pfundt, Rolph, Thiel, Christian T, Wiesener, Michael S, Aslanyan, Mariam G, Buchner, David A

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