Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite von Park, Daniel J., Lukens, Amanda K., Neafsey, Daniel E., Schaffner, Stephen F., Chang, Hsiao-Han, Valim, Clarissa, Ribacke, Ulf, Van Tyne, Daria, Galinsky, Kevin, Galligan, Meghan, Becker, Justin S., Ndiaye, Daouda, Mboup, Souleymane, Wiegand, Roger C., Hartl, Daniel L., Sabeti, Pardis C., Wirth, Dyann F., Volkman, Sarah K.

Volltext

Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance von Lukens, Amanda K., Ross, Leila Saxby, Heidebrecht, Richard, Gamo, Francisco Javier, Lafuente-Monasterio, Maria J., Booker, Michael L., Hartl, Daniel L., Wiegand, Roger C., Wirth, Dyann F.

Volltext

A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking von Daniels, Rachel, Volkman, Sarah K, Milner, Danny A, Mahesh, Nira, Neafsey, Daniel E, Park, Daniel J, Rosen, David, Angelino, Elaine, Sabeti, Pardis C, Wirth, Dyann F, Wiegand, Roger C

Volltext

Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum von Van Tyne, Daria, Park, Daniel J, Schaffner, Stephen F, Neafsey, Daniel E, Angelino, Elaine, Cortese, Joseph F, Barnes, Kayla G, Rosen, David M, Lukens, Amanda K, Daniels, Rachel F, Milner, Jr, Danny A, Johnson, Charles A, Shlyakhter, Ilya, Grossman, Sharon R, Becker, Justin S, Yamins, Daniel, Karlsson, Elinor K, Ndiaye, Daouda, Sarr, Ousmane, Mboup, Souleymane, Happi, Christian, Furlotte, Nicholas A, Eskin, Eleazar, Kang, Hyun Min, Hartl, Daniel L, Birren, Bruce W, Wiegand, Roger C, Lander, Eric S, Wirth, Dyann F, Volkman, Sarah K, Sabeti, Pardis C

Volltext

Seeking diagnostic and prognostic biomarkers for childhood bacterial pneumonia in sub-Saharan Africa: study protocol for an observational study von Valim, Clarissa, Olatunji, Yekin Ajauoi, Isa, Yasir Shitu, Salaudeen, Rasheed, Golam, Sarwar, Knol, Edward F, Kanyi, Sheriffo, Jammeh, Abdoulie, Bassat, Quique, de Jager, Wilco, Diaz, Alejandro A, Wiegand, Roger C, Ramirez, Julio, Moses, Marsha A, D’Alessandro, Umberto, Hibberd, Patricia L, Mackenzie, Grant A

Volltext

A High-Throughput Screen Targeting Malaria Transmission Stages Opens New Avenues for Drug Development von Buchholz, Kathrin, Burke, Thomas A., Williamson, Kim C., Wiegand, Roger C., Wirth, Dyann F., Marti, Matthias

Volltext

A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion von Egan, Elizabeth S., Jiang, Rays H. Y., Moechtar, Mischka A., Barteneva, Natasha S., Weekes, Michael P., Nobre, Luis V., Gygi, Steven P., Paulo, Joao A., Frantzreb, Charles, Tani, Yoshihiko, Takahashi, Junko, Watanabe, Seishi, Goldberg, Jonathan, Paul, Aditya S., Brugnara, Carlo, Root, David E., Wiegand, Roger C., Doench, John G., Duraisingh, Manoj T.

Volltext

In Vitro Resistance Selections for Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors Give Mutants with Multiple Point Mutations in the Drug-binding Site and Altered Gro... von Ross, Leila S., Gamo, Francisco Javier, Lafuente-Monasterio, Maria José, Singh, Onkar M.P., Rowland, Paul, Wiegand, Roger C., Wirth, Dyann F.

Volltext

Responses to Bacteria, Virus, and Malaria Distinguish the Etiology of Pediatric Clinical Pneumonia von Valim, Clarissa, Ahmad, Rushdy, Lanaspa, Miguel, Tan, Yan, Acácio, Sozinho, Gillette, Michael A, Almendinger, Katherine D, Milner, Jr, Danny A, Madrid, Lola, Pellé, Karell, Harezlak, Jaroslaw, Silterra, Jacob, Alonso, Pedro L, Carr, Steven A, Mesirov, Jill P, Wirth, Dyann F, Wiegand, Roger C, Bassat, Quique

Volltext

Genomic sequencing of Plasmodium falciparum malaria parasites from Senegal reveals the demographic history of the population von Chang, Hsiao-Han, Park, Daniel J, Galinsky, Kevin J, Schaffner, Stephen F, Ndiaye, Daouda, Ndir, Omar, Mboup, Souleymane, Wiegand, Roger C, Volkman, Sarah K, Sabeti, Pardis C, Wirth, Dyann F, Neafsey, Daniel E, Hartl, Daniel L

Volltext

Diversity-Oriented Synthesis Probe Targets Plasmodium falciparum Cytochrome b Ubiquinone Reduction Site and Synergizes With Oxidation Site Inhibitors von Lukens, Amanda K., Heidebrecht, Richard W., Mulrooney, Carol, Beaudoin, Jennifer A., Comer, Eamon, Duvall, Jeremy R., Fitzgerald, Mark E., Masi, Daniela, Galinsky, Kevin, Scherer, Christina A., Palmer, Michelle, Munoz, Benito, Foley, Michael, Schreiber, Stuart L., Wiegand, Roger C., Wirth, Dyann F.

Volltext

Diversity-Oriented Synthesis-Facilitated Medicinal Chemistry: Toward the Development of Novel Antimalarial Agents von Comer, Eamon, Beaudoin, Jennifer A, Kato, Nobutaka, Fitzgerald, Mark E, Heidebrecht, Richard W, Lee, Maurice duPont, Masi, Daniela, Mercier, Marion, Mulrooney, Carol, Muncipinto, Giovanni, Rowley, Ann, Crespo-Llado, Keila, Serrano, Adelfa E, Lukens, Amanda K, Wiegand, Roger C, Wirth, Dyann F, Palmer, Michelle A, Foley, Michael A, Munoz, Benito, Scherer, Christina A, Duvall, Jeremy R, Schreiber, Stuart L

Volltext

Transcriptional Categorization of the Etiology of Pneumonia Syndrome in Pediatric Patients in Malaria-Endemic Areas von Silterra, Jacob, Gillette, Michael A., Lanaspa, Miguel, Pellé, Karell G., Valim, Clarissa, Ahmad, Rushdy, Acácio, Sozinho, Almendinger, Katherine D., Tan, Yan, Madrid, Lola, Alonso, Pedro L., Carr, Steven A., Wiegand, Roger C., Bassat, Quique, Mesirov, Jill P., Milner, Danny A., Wirth, Dyann F.

Volltext

Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence von Neafsey, Daniel E, Schaffner, Stephen F, Volkman, Sarah K, Park, Daniel, Montgomery, Philip, Milner, Jr, Danny A, Lukens, Amanda, Rosen, David, Daniels, Rachel, Houde, Nathan, Cortese, Joseph F, Tyndall, Erin, Gates, Casey, Stange-Thomann, Nicole, Sarr, Ousmane, Ndiaye, Daouda, Ndir, Omar, Mboup, Soulyemane, Ferreira, Marcelo U, Moraes, Sandra do Lago, Dash, Aditya P, Chitnis, Chetan E, Wiegand, Roger C, Hartl, Daniel L, Birren, Bruce W, Lander, Eric S, Sabeti, Pardis C, Wirth, Dyann F

Volltext

Genomic Sequencing of Plasmodium falciparum Malaria Parasites from Senegal Reveals the Demographic History of the Population von Chang, Hsiao-Han, Park, Daniel J., Galinsky, Kevin J., Schaffner, Stephen F., Ndiaye, Daouda, Ndir, Omar, Mboup, Souleymane, Wiegand, Roger C., Volkman, Sarah K., Sabeti, Pardis C., Wirth, Dyann F., Neafsey, Daniel E., Hartl, Daniel L.

Volltext

Aminoindoles, a Novel Scaffold with Potent Activity against Plasmodium falciparum von BARKER, Robert H, URGAONKAR, Sameer, GUERRERO-BRAVO, Jose E, CRESPO-LLADO, Keila N, SERRANO, Adelfa E, LIN, Jing-Wen, JANSE, Chris J, KHAN, Shahid M, DURAISINGH, Manoj, COLEMAN, Bradley I, ANGULO-BARTUREN, Inigo, JIMENEZ-DIAZ, Maria Belén, MAZITSCHEK, Ralph, MAGAN, Noemi, GOMEZ, Vanesa, FERRER, Santiago, SANTOS MARTINEZ, Maria, WITTLIN, Sergio, PAPASTOGIANNIDIS, Petros, O'SHEA, Thomas, KLINGER, Jeffrey D, BREE, Mark, LEE, Edward, CELATKA, Cassandra, LEVINE, Mikaela, WIEGAND, Roger C, MUNOZ, Benito, WIRTH, Dyann F, CLARDY, Jon, BATHURST, Ian, SYBERTZ, Edmund, SKERLJ, Renato, CORTESE, Joseph F, TYNDALL, Erin, HANLAN LIU, CROMWELL, Mandy, BIR SIDHU, Amar

Volltext

A genome-wide map of diversity in Plasmodium falciparum von Wirth, Dyann F, Volkman, Sarah K, Sabeti, Pardis C, DeCaprio, David, Neafsey, Daniel E, Schaffner, Stephen F, Milner, Danny A, Daily, Johanna P, Sarr, Ousmane, Ndiaye, Daouda, Ndir, Omar, Mboup, Soulyemane, Duraisingh, Manoj T, Lukens, Amanda, Derr, Alan, Stange-Thomann, Nicole, Waggoner, Skye, Onofrio, Robert, Ziaugra, Liuda, Mauceli, Evan, Gnerre, Sante, Jaffe, David B, Zainoun, Joanne, Wiegand, Roger C, Birren, Bruce W, Hartl, Daniel L, Galagan, James E, Lander, Eric S

Volltext

Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria von Heidebrecht, Richard W, Mulrooney, Carol, Austin, Christopher P, Barker, Robert H, Beaudoin, Jennifer A, Cheng, Ken Chih-Chien, Comer, Eamon, Dandapani, Sivaraman, Dick, Justin, Duvall, Jeremy R, Ekland, Eric H, Fidock, David A, Fitzgerald, Mark E, Foley, Michael, Guha, Rajarshi, Hinkson, Paul, Kramer, Martin, Lukens, Amanda K, Masi, Daniela, Marcaurelle, Lisa A, Su, Xin-Zhuan, Thomas, Craig J, Weïwer, Michel, Wiegand, Roger C, Wirth, Dyann, Xia, Menghang, Yuan, Jing, Zhao, Jinghua, Palmer, Michelle, Munoz, Benito, Schreiber, Stuart

Volltext

Human cerebral malaria and Plasmodium falciparum genotypes in Malawi von Milner, Jr, Danny A, Vareta, Jimmy, Valim, Clarissa, Montgomery, Jacqui, Daniels, Rachel F, Volkman, Sarah K, Neafsey, Daniel E, Park, Daniel J, Schaffner, Stephen F, Mahesh, Nira C, Barnes, Kayla G, Rosen, David M, Lukens, Amanda K, Van Tyne, Daria, Wiegand, Roger C, Sabeti, Pardis C, Seydel, Karl B, Glover, Simon J, Kamiza, Steve, Molyneux, Malcolm E, Taylor, Terrie E, Wirth, Dyann F

Volltext

Three-dimensional structure of human cytomegalovirus protease von Shieh, Huey-Sheng, Kurumbail, Ravi G, Stevens, Anna M, Stegeman, Roderick A, Sturman, Eric J, Pak, Jina Y, Wittwer, Arthur J, Palmier, Mark O, Wiegand, Roger C, Holwerda, Barry C, Stallings, William C

Volltext